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Articles 42061 - 42090 of 42227
Full-Text Articles in Entire DC Network
An Unexpected Audience: Manner Manuals In Renaissance Europe, Jonathan Leece
An Unexpected Audience: Manner Manuals In Renaissance Europe, Jonathan Leece
The Forum: Journal of History
No abstract provided.
Review Of Williamjames Hull Hoffer, The Caning Of Charles Sumner: Honor, Idealism, And The Origins Of The Civil War, Daniel Lawrence Slusser
Review Of Williamjames Hull Hoffer, The Caning Of Charles Sumner: Honor, Idealism, And The Origins Of The Civil War, Daniel Lawrence Slusser
The Forum: Journal of History
No abstract provided.
Review Of Albert L. Hurtado, Intimate Frontiers; Kent G. Lightfoot, Indians, Missions, And Merchants; And James A. Sandos, Converting California, Hilda Iorga
The Forum: Journal of History
No abstract provided.
Methods Used To Integrate Stem Subjects Into K-12 Technology Education Classrooms, Matt Basilone
Methods Used To Integrate Stem Subjects Into K-12 Technology Education Classrooms, Matt Basilone
OTS Master's Level Projects & Papers
The problem of this study was to determine technology education teachers' use of methods to integrate science, technology, engineering, and mathematics into technology education courses for improved student learning of complex ideas.
A Study Of Poly Lactic Acid Bio-Polymer For Cereal Packaging, George Tuszkiewicz
A Study Of Poly Lactic Acid Bio-Polymer For Cereal Packaging, George Tuszkiewicz
Theses
The aim of this research has provided a technical framework for evaluating Co-Ex film structures of Poly Lactic Acid (PLA) and High Density Polyethylene (HDPE) for Ready to Eat (RTE) cereal primary packaging. This was accomplished through increased percentages of PLA content in each identified film candidate. The foundation for this research is that Bio Polymers are gaining market popularity as a result of the increasing world demand on plastics. As a result of plastics high market volatility and the strain on fossil fuel it has created focused research on Bio Polymers. However, it is widely known there are intrinsic …
Freight Transportation And The Environment: Using Geographic Information Systems To Inform Goods Movement Policy, Arindam Ghosh
Freight Transportation And The Environment: Using Geographic Information Systems To Inform Goods Movement Policy, Arindam Ghosh
Theses
The freight transportation sector is a major emitter of the greenhouse gas carbon dioxide (CO2) which has been recognized by numerous experts and science organizations as a significant contributor to climate change. The purpose of this thesis is to develop a a framework for obtaining the freight flows for containerized goods movement through the U.S. marine, highway, and rail systems and to estimate CO2 emissions associated with the freight traffic along interstate corridors that serve the three major U.S. ports on the West Coast, namely the port of Los Angeles and Long Beach, the Port of Oakland and the Port …
A Thermoelectric Generation Subsystem Model For Heat Recovery Simulations, Andrew Freedman
A Thermoelectric Generation Subsystem Model For Heat Recovery Simulations, Andrew Freedman
Theses
Thermoelectric devices can convert thermal energy directly into electrical energy, or they can work in reverse and use electrical energy to create a temperature gradient for cooling or heating applications. The absence of moving parts, wide range of operating temperatures, scalability, and modular capabilities makes thermoelectrics attractive for energy generation applications. They have been considered for use with vehicle exhausts, co-generation, and other energy recovery from lost heat in thermodynamic cycles. Thermoelectric devices have relatively low efficiencies but there have been recent advances in thermoelectric materials potentially opening the door to more power applications. As material advancements continue and a …
Compact Vision System For Monitoring Of 3d Weld Pool Surface In Pipe Welding, Alexander Phillip Maroudis
Compact Vision System For Monitoring Of 3d Weld Pool Surface In Pipe Welding, Alexander Phillip Maroudis
University of Kentucky Master's Theses
Human welders have long been able to monitor a weld pool and adjust welding parameters accordingly. Automated welding robots can provide consistent movement during the welding process, but lack the ability to monitor the weld pool. A vision system attached to the welding robot could provide a way to monitor the weld pool substantially faster than a human being. Previous vision systems to monitor weld pool surfaces have been developed, but their uses are limited since the system is fixed in place. The compact vision system developed in this research attaches directly to the welding torch, which provides no limitations …
Particulate Organic Carbon Fate And Transport In A Lowland, Temperate Watershed, William Isaac Ford Iii
Particulate Organic Carbon Fate And Transport In A Lowland, Temperate Watershed, William Isaac Ford Iii
University of Kentucky Master's Theses
Small lowland agricultural systems promote conditions where benthic biological communities can thrive. These biogeochemical processes have significant impacts on terrestrial ecosystem processes including POC flux and fate, nutrient balances, water quality budges, and aquatic biological functioning. Limited information is available on coupled biological and hydrologic processes in fluvial systems. This study investigates the mixture of biological and hydrologic processes in the benthic layer in order to understand POC cycling in the South Elkhorn system. Further, comprehensive modeling of POC flux in lowland systems has not been performed previously and the behavior of potentially controlling variables, such as hydrologic forcing and …
Kentucky Traffic Collision Facts 2011 Report, Kentucky Transportation Center, Kentucky State Police
Kentucky Traffic Collision Facts 2011 Report, Kentucky Transportation Center, Kentucky State Police
Kentucky Transportation Center Research Report
KENTUCKY’S TRAFFIC COLLISION FACTS report for 2011 is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised Statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize data on traffic collisions for such purposes as will improve the traffic safety program in the Commonwealth. Data contained in this report are based solely on the observations …
Analysis Of The Effects Of 12 Months Accelerated Aging Testing, Obtained At Two Equivalent Aging Programs, On A Medical Grade Proprietary Chevron Pouch, Laurie Carletta Kruczynski
Analysis Of The Effects Of 12 Months Accelerated Aging Testing, Obtained At Two Equivalent Aging Programs, On A Medical Grade Proprietary Chevron Pouch, Laurie Carletta Kruczynski
Theses
The Food and Drug Administration requires that all sterile medical devices be tested and documented for a labeled shelflife. This thesis analyzed the effects of 12 months of accelerated aging testing, obtained at two equivalent aging programs, on a medical-grade chevron pouch constructed from a proprietary BOPET/PE film sealed to 1073B uncoated Tyvek®. The equivalent of 12 of months accelerated aging was obtained at 55°C and 70°C, and samples were also evaluated pre-aging to serve as a baseline for comparison. The aging model was based upon ASTM F-1980, "Standard Guide For Accelerated Aging of Sterile Barrier Systems for Medical Devices" …
Special Issue On Information Dissemination And New Services In P2p Systems, Min Song, Sachin Shetty, Wenbin Jiang, E. K. Park
Special Issue On Information Dissemination And New Services In P2p Systems, Min Song, Sachin Shetty, Wenbin Jiang, E. K. Park
Electrical & Computer Engineering Faculty Publications
Information dissemination is an important P2P application that has received considerable research attention in recent years. P2P information dissemination systems range from simple file sharing applications to more complex systems that allows users to securely and efficiently publish, organize, index, search, update and retrieve data in a distributed storage medium. For complex P2P information dissemination systems, there is a need for features which include security, anonymity, fairness, scalability, resource management, and organization capabilities. For effective information dissemination, following features of P2P systems and infrastructure need to be updated: distributed object location and routing mechanisms, novel approaches to content replication, caching …
Precise Control Of Highly Ordered Arrays Of Nested Semiconductor/Metal Nanotubes, Diefeng Gu, Helmut Baumgart, Kandabara Tapily, Pragya Shrestha, Gon Namkoong, Xianyu Ao, Frank Müller
Precise Control Of Highly Ordered Arrays Of Nested Semiconductor/Metal Nanotubes, Diefeng Gu, Helmut Baumgart, Kandabara Tapily, Pragya Shrestha, Gon Namkoong, Xianyu Ao, Frank Müller
Electrical & Computer Engineering Faculty Publications
Lithographically defined microporous templates in conjunction with the atomic layer deposition (ALD) technique enable remarkable control of complex novel nested nanotube structures. So far three-dimensional control of physical process parameters has not been fully realized with high precision resolution, and requires optimization in order to achieve a wider range of potential applications. Furthermore, the combination of composite insulating oxide layers alternating with semiconducting layers and metals can provide various types of novel applications and eventually provide unique and advanced levels of multifunctional nanoscale devices. Semiconducting TiO2 nanotubes have potential applications in photovoltaic devices. The combination of nanostructured semiconducting materials …
Global Economies, Regulatory Failure, And Loose Money: Lessons For Regulating The Finance Sector From Iceland's Financial Crisis, Birgir T. Petursson, Andrew P. Morriss
Global Economies, Regulatory Failure, And Loose Money: Lessons For Regulating The Finance Sector From Iceland's Financial Crisis, Birgir T. Petursson, Andrew P. Morriss
Faculty Scholarship
Iceland was the first developed economy to fall into crisis in 2008, with the collapse of its banking sector, currency value, and economy. The collapse threw Iceland into a political crisis and provoked a serious international dispute between Iceland and Britain and the Netherlands over responsibility for the failed banks. Prior to 2008, Iceland had been treated as the poster child for deregulation; since 2008, it has been held up as the poster child for the dangers offinancial liberalization. Neither is accurate. Rather, Iceland presents a cautionary tale about the interrelationships between fiscal and monetary policy and regulatory measures. Excessive …
How To Be A Hero: A Rhetorical Analysis Of Superman's First Appearance In Action Comics, Sevan Michael Paris
How To Be A Hero: A Rhetorical Analysis Of Superman's First Appearance In Action Comics, Sevan Michael Paris
Masters Theses and Doctoral Dissertations
Through a combination of rhetorical heightening, idiom, and structure, Superman creators Jerry Siegel and Joe Shuster influenced their young American audience with the first appearance of Superman in 1938’s Action Comics no. 1. Superman’s lack of distinguishing characteristics, dual identity, and embodiment of American culture allowed the character to become a vehicle for Siegel and Shuster, persuading children to be a helper of those in need and champion of the oppressed. Varying panel size and choosing what to show from what not to show allowed Siegel and Shuster to heighten specific moments within Superman’s story. Through metaphor and symbolic modeling, …
Caught In A Preventive Dragnet: Selective Counterterrorism In A Post 9/11 America, Sahar F. Aziz
Caught In A Preventive Dragnet: Selective Counterterrorism In A Post 9/11 America, Sahar F. Aziz
Faculty Scholarship
While post-9/11 preventive counterterrorism policies have adversely impacted various groups of Americans, no group has been more profoundly affected than the Muslim, Arab, and South Asian communities. Mosque infiltration has become so rampant that some congregants assume they are under surveillance as they fulfill their religious obligations. Government informants have ensnared numerous, seemingly hapless and unsophisticated young men such that Muslims no longer know whom they can trust among each other. Aggressive prosecutions of Muslim charities and individuals across the country have embittered communities that now feel under siege by their government and distrusted by their non-Muslim compatriots.19 Selective counterterrorism …
Soil Fertility And Crop Yields In Long-Term Organic And Conventional Cropping Systems In Eastern Nebraska, Samuel E. Wortman, Tomie D. Galusha, Stephen C. Mason, Charles A. Francis
Soil Fertility And Crop Yields In Long-Term Organic And Conventional Cropping Systems In Eastern Nebraska, Samuel E. Wortman, Tomie D. Galusha, Stephen C. Mason, Charles A. Francis
Department of Agronomy and Horticulture: Faculty Publications
Organic agriculture aims to build soil quality and provide long-term benefits to people and the environment; however, organic practices may reduce crop yields. This long-term study near Mead, NE was conducted to determine differences in soil fertility and crop yields among conventional and organic cropping systems between 1996 and 2007. The conventional system (CR) consisted of corn (Zea mays L.) or sorghum (Sorghum bicolor (L.) Moench)–soybean (Glycine max (L.) Merr.)–sorghum or corn–soybean, whereas the diversified conventional system (DIR) consisted of corn or sorghum– sorghum or corn–soybean–winter wheat (wheat, Triticum aestivum L.). The animal manure-based organic system (OAM) …
Buried Treasure Or Buried Hope? The Status Of Mexico-U.S. Transboundary Aquifers Under International Law, Gabriel E. Eckstein
Buried Treasure Or Buried Hope? The Status Of Mexico-U.S. Transboundary Aquifers Under International Law, Gabriel E. Eckstein
Faculty Scholarship
Transboundary aquifers found along the 2,000 mile-long border between Mexico and the United States are not governed by any treaty. Yet, these aquifers are the primary source of water for many of the twelve million people who live in this parched region. The region’s groundwater, however, is being over-exploited and contaminated, which is threatening the very life that it currently sustains. As populations continue to expand and current rates of haphazard development persist, the absence of an agreement for the management and allocation of this critical resource could lead to bi-national economic, social and environmental tragedies. This study reviews groundwater …
Multilayer Network Resilience Analysis And Experimentation On Geni, Justin P. Rohrer, Egemen K. Çetinkaya, James P. G. Sterbenz
Multilayer Network Resilience Analysis And Experimentation On Geni, Justin P. Rohrer, Egemen K. Çetinkaya, James P. G. Sterbenz
Electrical and Computer Engineering Faculty Research & Creative Works
GENI is evolving to provide a promising environment in which to do experimental research in the resilience and survivability of future networks, by allowing programmable control over topology and mechanism, while providing the scale and global reach needed to conduct network experiments far beyond the capabilities of a conventional testbed. We will use GENI in general, and the GpENI infrastructure (expanding to 40 clusters with 200 nodes worldwide), federated with the larger GENI PlanetLab control framework and interconnected to several ProtoGENI facilities to perform resilience and survivability experiments at scale, both in terms of node count and with the geographic …
Eeg Artifact Removal Using A Wavelet Neural Network, Hoang-Anh T. Nguyen, John Musson, Jiang Li, Frederick Mckenzie, Guangfan Zhang, Roger Xu, Carl Richey, Tom Schnell, Thomas E. Pinelli (Ed.)
Eeg Artifact Removal Using A Wavelet Neural Network, Hoang-Anh T. Nguyen, John Musson, Jiang Li, Frederick Mckenzie, Guangfan Zhang, Roger Xu, Carl Richey, Tom Schnell, Thomas E. Pinelli (Ed.)
Electrical & Computer Engineering Faculty Publications
In this paper we developed a wavelet neural network. (WNN) algorithm for Electroencephalogram (EEG) artifact removal without electrooculographic (EOG) recordings. The algorithm combines the universal approximation characteristics of neural network and the time/frequency property of wavelet. We compared the WNN algorithm with the ICA technique and a wavelet thresholding method, which was realized by using the Stein's unbiased risk estimate (SURE) with an adaptive gradient-based optimal threshold. Experimental results on a driving test data set show that WNN can remove EEG artifacts effectively without diminishing useful EEG information even for very noisy data.
A Systematic Approach For Engagement Analysis Under Multitasking Environments, Guangfan Zhang, John Leddo, Roger Xu, Carl Richey, Tom Schnell, Frederick Mckenzie, Jiang Li, Thomas E. Pinelli (Ed.)
A Systematic Approach For Engagement Analysis Under Multitasking Environments, Guangfan Zhang, John Leddo, Roger Xu, Carl Richey, Tom Schnell, Frederick Mckenzie, Jiang Li, Thomas E. Pinelli (Ed.)
Electrical & Computer Engineering Faculty Publications
An overload condition can lead to high stress for an operator and further cause substantial drops in performance. On the other extreme, in automated systems, an operator may become underloaded; in which case, it is difficult for the operator to maintain sustained attention. When an unexpected event occurs, either internal or external to the automated system, a disengaged operation may neglect, misunderstand, or respond slowly/inappropriately to the situation. In this paper, we discuss a systematic approach monitor for extremes of cognitive workload and engagement in multitasking environments. Inferences of cognitive workload and engagement are based on subjective evaluations, objective performance …
Prediction Of Brain Tumor Progression Using Multiple Histogram Matched Mri Scans, Debrup Banerjee, Loc Tran, Jiang Li, Yuzhong Shen, Frederic Mckenzie, Jihong Wang, Ronald M. Summers (Ed.), Bram Van Ginneken (Ed.)
Prediction Of Brain Tumor Progression Using Multiple Histogram Matched Mri Scans, Debrup Banerjee, Loc Tran, Jiang Li, Yuzhong Shen, Frederic Mckenzie, Jihong Wang, Ronald M. Summers (Ed.), Bram Van Ginneken (Ed.)
Electrical & Computer Engineering Faculty Publications
In a recent study [1], we investigated the feasibility of predicting brain tumor progression based on multiple MRI series and we tested our methods on seven patients' MRI images scanned at three consecutive visits A, B and C. Experimental results showed that it is feasible to predict tumor progression from visit A to visit C using a model trained by the information from visit A to visit B. However, the trained model failed when we tried to predict tumor progression from visit B to visit C, though it is clinically more important. Upon a closer look at the MRI scans …
Automatic Detection Of Aircraft Emergency Landing Sites, Yu-Fei Shen, Zia-Ur Rahman, Dean Krusienski, Jiang Li, Zia-Ur Rahman (Ed.), Stephen E. Reichenbach (Ed.), Mark Allen Neifeld (Ed.)
Automatic Detection Of Aircraft Emergency Landing Sites, Yu-Fei Shen, Zia-Ur Rahman, Dean Krusienski, Jiang Li, Zia-Ur Rahman (Ed.), Stephen E. Reichenbach (Ed.), Mark Allen Neifeld (Ed.)
Electrical & Computer Engineering Faculty Publications
An automatic landing site detection algorithm is proposed for aircraft emergency landing. Emergency landing is an unplanned event in response to emergency situations. If, as is unfortunately usually the case, there is no airstrip or airfield that can be reached by the un-powered aircraft, a crash landing or ditching has to be carried out. Identifying a safe landing site is critical to the survival of passengers and crew. Conventionally, the pilot chooses the landing site visually by looking at the terrain through the cockpit. The success of this vital decision greatly depends on the external environmental factors that can impair …
Effect Of Nitrogen Fertilizer Rate And Harvest Season On Forage Yield, Quality, And Macronutrient Concentrations In Midland Bermuda Grass, Maru K. Kering, John A. Guretzky, Eddie Funderburg, Jagadeesh Mosali
Effect Of Nitrogen Fertilizer Rate And Harvest Season On Forage Yield, Quality, And Macronutrient Concentrations In Midland Bermuda Grass, Maru K. Kering, John A. Guretzky, Eddie Funderburg, Jagadeesh Mosali
Department of Agronomy and Horticulture: Faculty Publications
Bermuda grass [Cynodon dactylon (L.) Pers.] is a major forage for grazing and hay production in the southern United States. The objectives of this study were to determine effects of nitrogen (N) fertilization rate (0, 112, 224, 336, and 448 kg ha−1), split spring and summer applications of N at the 224 and 448 kg ha−1 rates, and harvest periods (spring and summer) on forage yield, crude protein (CP), acid detergent fiber (ADF), neutral detergent fiber (NDF), total digestible nutrients (TDN), and concentrations of phosphorus (P), potassium (K), magnesium (Mg), and calcium (Ca) in Midland Bermuda …
Switchgrass For Forage And Bioenergy: Harvest And Nitrogen Rate Effects On Biomass Yields And Nutrient Composition, John A. Guretzky, Jon T. Biermacher, Billy Cook, Maru K. Kering, Jagadeesh Mosali
Switchgrass For Forage And Bioenergy: Harvest And Nitrogen Rate Effects On Biomass Yields And Nutrient Composition, John A. Guretzky, Jon T. Biermacher, Billy Cook, Maru K. Kering, Jagadeesh Mosali
Department of Agronomy and Horticulture: Faculty Publications
Switchgrass (Panicum virgatum L.) may have value as forage and a bioenergy feedstock. Our objective was to evaluate how harvest system and N fertilizer rates affected biomass yield and nutrient composition of young stands of switchgrass (cv. Alamo) in the southern Great Plains, USA. Nitrogen fertilization increased biomass yields from 10.4, 10.8, and 12.2 Mg ha−1 at 0 kg N ha−1 to 13.7, 14.6, and 21.0 Mg ha−1 at 225 kg N ha−1 when harvested after seed set (October), after frost (December), and twice per year after boot stage (July) and frost, respectively. Nutrient concentrations …
Learning Gains And Response To Digital Lessons On Soil Genesis And Development, Martha Mamo, James A. Ippolito, Timothy A. Kettler, Ronald Reuter, Dennis L. Mccallister, Patricia Morner, Dann E. Husmann, Erin E. Blankenship
Learning Gains And Response To Digital Lessons On Soil Genesis And Development, Martha Mamo, James A. Ippolito, Timothy A. Kettler, Ronald Reuter, Dennis L. Mccallister, Patricia Morner, Dann E. Husmann, Erin E. Blankenship
Department of Agronomy and Horticulture: Faculty Publications
Evolving computer technology is offering opportunities for new online approaches in teaching methods and delivery. Well-designed web-based (online) lessons should reinforce the critical need of the soil science discipline in today's food, energy, and environmental issues, as well as meet the needs of the diverse clientele with interest in agricultural and/ or environmental disciplines. The objectives of the project were to: (1) develop web-based lessons in soil genesis and development and (2) evaluate context-based case studies or application lessons (agronomic, environmental, and ecological situations) to teach soil genesis and development. Six principles lessons, along with three applications lessons, were developed …
High-Yield Irrigated Maize In The Western U.S. Corn Belt: I. On-Farm Yield, Yield Potential, And Impact Of Agronomic Practices, Patricio Grassini, John Thorburn, Charles Burr, Kenneth Cassman
High-Yield Irrigated Maize In The Western U.S. Corn Belt: I. On-Farm Yield, Yield Potential, And Impact Of Agronomic Practices, Patricio Grassini, John Thorburn, Charles Burr, Kenneth Cassman
Department of Agronomy and Horticulture: Faculty Publications
Quantifying the exploitable gap between average farmer yields and yield potential (YP) is essential to prioritize research and formulate policies for food security at national and international levels. While irrigated maize accounts for 58% of total annual maize production in the Western U.S. Corn Belt, current yield gap in these systems has not been quantified. Our objectives were to quantify YP, yield gaps, and the impact of agronomic practices on both parameters in irrigated maize systems of central Nebraska. The analysis was based on a 3-y database with field-specific values for yield, applied irrigation, and N …
Biological Suppression Of Velvetleaf (Abutilon Theophrasti ) In An Eastern Nebraska Soil, Jane Okalebo, Gary Y. Yuen, Rhae A. Drijber, Erin E. Blankenship, Cafer Eken, John L. Lindquist
Biological Suppression Of Velvetleaf (Abutilon Theophrasti ) In An Eastern Nebraska Soil, Jane Okalebo, Gary Y. Yuen, Rhae A. Drijber, Erin E. Blankenship, Cafer Eken, John L. Lindquist
Department of Agronomy and Horticulture: Faculty Publications
Weed-suppressive soils contain naturally occurring microorganisms that suppress a weed by inhibiting its growth, development, and reproductive potential. Increased knowledge of microbe–weed interactions in such soils could lead to the identification of management practices that create or enhance soil suppressiveness to weeds. Velvetleaf death and growth suppression was observed in a research field (fieldA) that was planted with high populations of velvetleaf, which may have developed via microbial mediated plant–soil feedback. Greenhouse studies were conducted with soil collected from fieldA (soilA) to determine if it was biologically suppressive to velvetleaf. In one study, mortality of velvetleaf …
Universal Binding And Recoil Corrections To Bound State G-Factors, Timothy James Semple Martin
Universal Binding And Recoil Corrections To Bound State G-Factors, Timothy James Semple Martin
University of Kentucky Doctoral Dissertations
The gyromagnetic ratio of bound particles is an active field of experimental and theoretical research. Early measurements of corrections to the bound g-factor came from experiments involving hydrogen-like ions. As the sensitivity of such experiments has increased, it has become possible to instead use them to measure the electron-ion mass ratio -- but only if the theoretical bound g-factor is known with sufficient precision for these systems. By constructing an effective nonrelativistic Lagrangian, we derive leading order binding and recoil corrections for systems comprised of particles with arbitrary spin.
Lagrangians for spin one-half and spin one-theories are developed, …
Evaluation Of The Physicochemical Properties And Stability Of Solid Lipid Nanoparticles Designed For The Delivery Of Dexamethasone To Tumors, Melissa Howard
Evaluation Of The Physicochemical Properties And Stability Of Solid Lipid Nanoparticles Designed For The Delivery Of Dexamethasone To Tumors, Melissa Howard
University of Kentucky Doctoral Dissertations
Pre-clinical and clinical trials suggest that pre-treatment with dexamethasone (Dex) may facilitate enhanced uptake of subsequently administered chemotherapeutic agents. To reduce the side effects associated with systemic administration of Dex, solid lipid nanoparticles (SLNs) containing dexamethasone palmitate (Dex-P) were prepared as a means of achieving tumor-targeted drug delivery. These studies were aimed at evaluating the physicochemical properties and both the physiological and storage stability of the SLNs.
SLNs were prepared using nanotemplate engineering technology. Stearyl alcohol (SA) was used as the lipid phase with Brij® 78 and Polysorbate 60 as surfactants and PEG6000 monostearate as a long-chain PEGylating agent. …