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2011

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On The Incidence Of Pulmonary Embolism In Spinal Arthrodesis And The Need For Better Evidence And Prevention Guidelines, Zachary J. Senders, Bs, Benjamin Zussman, Bs, James S. Harrop, Md Nov 2011

On The Incidence Of Pulmonary Embolism In Spinal Arthrodesis And The Need For Better Evidence And Prevention Guidelines, Zachary J. Senders, Bs, Benjamin Zussman, Bs, James S. Harrop, Md

JHN Journal

Pulmonary Embolism (PE) is a rare but serious event that may occur after spinal surgery. Vascular endothelial damage during surgery and immobilization of the patient after surgery contribute to a higher risk of thrombosis and subsequent PE. Prophylaxis including intermittent pneumatic compression stockings, heparin, and other interventions is often employed by the treatment team to lower the risk of thromboembolic complications. In orthopedic, trauma, burn and other high-risk surgical patients, the incidence of PE has been thoroughly studied, and this knowledge has been used to establish prophylaxis guidelines specifically for these patients. The incidence of PE in spinal fusion patients, …

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Surgical Management Of Fungal Vertebral Osteomyelitis, Benjamin M. Zussman, Bs, David L. Penn, Ms, James S. Harrop, Md Nov 2011

Surgical Management Of Fungal Vertebral Osteomyelitis, Benjamin M. Zussman, Bs, David L. Penn, Ms, James S. Harrop, Md

JHN Journal

Fungal vertebral osteomyelitis (FVO) is an uncommon but aggressive disease that may cause spinal instability, neurological insult, and possible death. Little data about treatment strategies and patient outcomes exist. A retrospective review of medical and surgical management with follow-up of this disease was performed.

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Bevacizumab: A Controversial Agent Against High-Grade Gliomas, Sussan Salas, Md, Miguel Guzman, Md, Kevin Judy, Md Nov 2011

Bevacizumab: A Controversial Agent Against High-Grade Gliomas, Sussan Salas, Md, Miguel Guzman, Md, Kevin Judy, Md

JHN Journal

Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. Despite the current regimen of surgical resection with subsequent external beam radiotherapy and temozolomide, mean survival is 14.6 months and 2-year survival is 26%. GBM is a highly vascular tumor, a result of its increased expression of vascular endothelial growth factor (VEGF) compared to other brain tumors. VEGF promotes endothelial cell proliferation, and is thought to have a pivotal role during tumor progression. Multiple treatment modalities have targeted VEGF and VEGF receptors (VEGFTs) due to their essential roles in the regulation of angiogenic processes. Bevacizumab is a …

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Case Report On Intracranial Hemorrhage Related To Type I Cryoglobulinemia, Richard Dalyai, Md, L. Fernando Gonzalez, Md Nov 2011

Case Report On Intracranial Hemorrhage Related To Type I Cryoglobulinemia, Richard Dalyai, Md, L. Fernando Gonzalez, Md

JHN Journal

A traumatic intracranial hemorrhage (ICH) is a common neurosurgical pathology that affects about 20 of 100,000 people every year with a mortality of at least 40%. However, a specific etiology, cannot be identified in about 30% of spontaneous ICH. Here, we present a rare case of ICH related to a patient's previously undiagnosed cryoglobinemia.

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Quantification Of Vascular Perfusion In The Spinal Cord After Injury., Ruthie S. Fligor Nov 2011

Quantification Of Vascular Perfusion In The Spinal Cord After Injury., Ruthie S. Fligor

Electronic Theses and Dissertations

Traumatic injury destroys blood vessels at the injury epicenter and is followed by local angiogenesis and regional inflammation. Healing from injury depends on vascular health because blood supply is directly responsible for the health and function of surrounding tissue. This work establishes a new method for qualitatively and quantitatively measuring the blood supply of spinal cord (SC) tissue. Systemically injecting fluorescent microspheres (FMs) and cryostat sectioning SC tissue reveals a novel and potentially powerful way of assessing blood supply. This method is easily incorporated with existing tissue processing protocols because it does not require chemical digestion of the tissue region …

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Back Talk -- Obama And Collection Development, Anthony (Tony) W. Ferguson Nov 2011

Back Talk -- Obama And Collection Development, Anthony (Tony) W. Ferguson

Against the Grain

No abstract provided.

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Atg Interviews Tim Babbitt And Kevin Sayar, Tom Gilson, Katina Strauch Nov 2011

Atg Interviews Tim Babbitt And Kevin Sayar, Tom Gilson, Katina Strauch

Against the Grain

No abstract provided.

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Atg Interviews John G. Dove, Tom Gilson, Katina Strauch Nov 2011

Atg Interviews John G. Dove, Tom Gilson, Katina Strauch

Against the Grain

No abstract provided.

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Full Page Ads Nov 2011

Full Page Ads

Against the Grain

No abstract provided.

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People Profile: Stephen Rhind-Tutt Nov 2011

People Profile: Stephen Rhind-Tutt

Against the Grain

No abstract provided.

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Book Reviews -- Monographic Musings, Debbie Vaughn Nov 2011

Book Reviews -- Monographic Musings, Debbie Vaughn

Against the Grain

No abstract provided.

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Atg Interviews Stephen Rhind-Tutt, Tom Gilson, Katina Strauch Nov 2011

Atg Interviews Stephen Rhind-Tutt, Tom Gilson, Katina Strauch

Against the Grain

No abstract provided.

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And They Were There: Reports Of Meetings -- Salalm 56 And The 30th Annual Charleston Conference, Sever Bordeianu Nov 2011

And They Were There: Reports Of Meetings -- Salalm 56 And The 30th Annual Charleston Conference, Sever Bordeianu

Against the Grain

No abstract provided.

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From The Reference Desk, Tom Gilson Nov 2011

From The Reference Desk, Tom Gilson

Against the Grain

No abstract provided.

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Detection And Characterization Of A Distinct Bornavirus Lineage From Healthy Canada Geese (Branta Canadensis), Susan Payne, Lina Covaleda, Guo Jianhua, Seth Swafford, John A. Baroch, Pamela J. Ferro, Blanca Lupiani, J Jill Heatley, Ian Tizard Nov 2011

Detection And Characterization Of A Distinct Bornavirus Lineage From Healthy Canada Geese (Branta Canadensis), Susan Payne, Lina Covaleda, Guo Jianhua, Seth Swafford, John A. Baroch, Pamela J. Ferro, Blanca Lupiani, J Jill Heatley, Ian Tizard

United States Department of Agriculture Wildlife Services: Staff Publications

Avian bornaviruses (ABV), identified in 2008, infect captive parrots and macaws worldwide. The natural reservoirs of these viruses are unknown. Reverse transcription-PCR (RT-PCR) was used to screen oropharyngeal/ cloacal swab and brain samples from wild Canada geese (Branta canadensis) for ABV. Approximately 2.9% of swab samples were positive for bornavirus sequences. Fifty-two percent of brain samples from 2 urban flocks also tested positive, and brain isolates were cultured in duck embryo fibroblasts. Phylogenetic analyses placed goose isolates in an independent cluster, and more notably, important regulatory sequences present in Borna disease virus but lacking in psittacine ABVs were …

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The Raf/Mek/Extracellular Signal-Regulated Kinase 1/2 Pathway Can Mediate Growth Inhibitory And Differentiation Signaling Via Androgen Receptor Downregulation In Prostate Cancer Cells., Seung-Keun Hong, Jin-Hwan Kim, Ming-Fong Lin, Jong-In Park Nov 2011

The Raf/Mek/Extracellular Signal-Regulated Kinase 1/2 Pathway Can Mediate Growth Inhibitory And Differentiation Signaling Via Androgen Receptor Downregulation In Prostate Cancer Cells., Seung-Keun Hong, Jin-Hwan Kim, Ming-Fong Lin, Jong-In Park

Journal Articles: Biochemistry & Molecular Biology

Upregulated ERK1/2 activity is correlated with androgen receptor (AR) downregulation in certain prostate cancer (PCa) that exhibits androgen deprivation-induced neuroendocrine differentiation, but its functional relevance requires elucidation. We found that sustained ERK1/2 activation using active Raf or MEK1/2 mutants is sufficient to induce AR downregulation at mRNA and protein levels in LNCaP. Downregulation of AR protein, but not mRNA, was blocked by proteasome inhibitors, MG132 and bortezomib, indicating that the pathway regulation is mediated at multiple points. Ectopic expression of a constitutively active AR inhibited Raf/MEK/ERK-mediated regulation of the differentiation markers, neuron-specific enolase and neutral endopeptidase, and the cyclin-dependent kinase …

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Recollection Is Impaired By The Modification Of Interpretation Bias, Paula T. Hertel, Elaina Vasquez, Amanda Benbow, Megan Hughes Nov 2011

Recollection Is Impaired By The Modification Of Interpretation Bias, Paula T. Hertel, Elaina Vasquez, Amanda Benbow, Megan Hughes

Psychology Faculty Research

The interpretation paradigm of cognitive-bias modification (CBM-I) was modified with instructions used in process-dissociation procedures for the purpose of investigating processes contributing to performance on the transfer task. In Experiment 1 nonanxious students were trained to interpret ambiguous situations in either a negative or benign way (or they read nonambiguous scenarios). They were then asked to respond to new ambiguous situations in the same way as contextually similar analogues during training, or to respond differently. Benign training proactively impaired memory for negative outcomes. This effect was replicated by anxious students in Experiment 2 and discussed with respect to the assumptions …

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The Freshwater Mussels (Mollusca: Bivalvia: Unionoida) Of Nebraska, Ellet Hoke Nov 2011

The Freshwater Mussels (Mollusca: Bivalvia: Unionoida) Of Nebraska, Ellet Hoke

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

This paper reports the results of the first statewide survey of the freshwater mussels of Nebraska. Survey goals were: (1) to document current distributions through collection of recent shells; (2) to document former distributions through collection of relict shells and examination of museum collections; (3) to identify changes in distribution; (4) to identify the primary natural and anthropomorphic factors impacting unionids; and (5) to develop a model to explain the documented distributions. The survey confirmed 30 unionid species and the exotic Corbicula fluminea for the state, and museum vouchers documented one additional unionid species. Analysis of museum records and an …

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Childhood Obesity And Blood Pressure: Back To The Future?, Bonita Falkner, Samuel Gidding Nov 2011

Childhood Obesity And Blood Pressure: Back To The Future?, Bonita Falkner, Samuel Gidding

Department of Pediatrics Faculty Papers

The prevalence of childhood hypertension is increasing.1, 2 Studies that apply the 95th percentile definition and repeat measurements on three separate visits, report a pediatric hypertension prevalence of approximately 3.5%3, 4, and among obese children and adolescents the prevalence of both hypertension and prehypertension is even greater. The recently documented increase in hypertension among the young is due largely to the childhood obesity epidemic and possibly other secular changes in lifestyles. These publications and others confirm that hypertension is a prevalent child health condition, especially among overweight and obese children. A consistent positive association between body …

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Distribution Of Zooplankton In Harlan County Reservoir, Nebraska, Kathy M. Maline, Keith D. Koupal, Brian C. Peterson, W. Wyatt Hoback Nov 2011

Distribution Of Zooplankton In Harlan County Reservoir, Nebraska, Kathy M. Maline, Keith D. Koupal, Brian C. Peterson, W. Wyatt Hoback

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

The objective of this study was to determine the horizontal and vertical distribution of zooplankton in Harlan County Reservoir in order to assist in developing an appropriate zooplankton sampling regime for this and similar Nebraska irrigation reservoirs. Samples were collected at 16 sites distributed across 3 zones of the reservoir monthly in April, May, June, and July of 2007 using a 2.2 L Van Dorn sampler. Samples were collected at depths of 1, 4, and 7 meters, poured through an 80-μm filter, preserved, and identified to the lowest possible taxa. Total zooplankton densities in Harlan County Reservoir were statistically similar …

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A False Start In The Race Against Doping In Sport: Concerns With Cycling’S Biological Passport, Nicholas Hailey Nov 2011

A False Start In The Race Against Doping In Sport: Concerns With Cycling’S Biological Passport, Nicholas Hailey

Duke Law Journal

Professional cycling has suffered from a number of doping scandals. The sport’s governing bodies have responded by implementing an aggressive new antidoping program known as the biological passport. Cycling’s biological passport marks a departure from traditional antidoping efforts, which have focused on directly detecting prohibited substances in a cyclist’s system. Instead, the biological passport tracks biological variables in a cyclist’s blood and urine over time, monitoring for fluctuations that are thought to indirectly reveal the effects of doping. Although this method of indirect detection is promising, it also raises serious legal and scientific concerns. Since its introduction, the cycling community …

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The Utilization Of A Sub-Glottic Endotracheal Tube To Reduce Ventilator Associated Pneumonia Rate, Kenneth Miller Med, Rrt-Nps, Robert Leshko Bs,Rrt, Angela Lutz Bs, Rrt-Nps, Linda Cornman Bs, Rrt-Nps Nov 2011

The Utilization Of A Sub-Glottic Endotracheal Tube To Reduce Ventilator Associated Pneumonia Rate, Kenneth Miller Med, Rrt-Nps, Robert Leshko Bs,Rrt, Angela Lutz Bs, Rrt-Nps, Linda Cornman Bs, Rrt-Nps

Patient Care Services / Nursing

No abstract provided.

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Event Perception, Gabriel A. Radvansky, Jeffrey M. Zacks Nov 2011

Event Perception, Gabriel A. Radvansky, Jeffrey M. Zacks

Psychological & Brain Sciences Faculty Research

Events are central elements of human experience. Formally, they can be individuated in terms of the entities that compose them, the features of those entities, and the relations amongst entities. Psychologically, representations of events capture their spatiotemporal location, the people and objects involved, and the relations between these elements. Here, we present an account of the nature of psychological representations of events and how they are constructed and updated. Event representations are like images in that they are isomorphic to the situations they represent. However, they are like models or language in that they are constructed of components rather than …

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Venous Thromboembolism Risk And Prophylaxis In A Saudi Hospital., Rifat S. Rehmani, Javed I. Memon, Abdulsalam Alaithan, Alaa Ghabashi, Khalida Shahid, Shahid Latif, Munera A. Swailem Nov 2011

Venous Thromboembolism Risk And Prophylaxis In A Saudi Hospital., Rifat S. Rehmani, Javed I. Memon, Abdulsalam Alaithan, Alaa Ghabashi, Khalida Shahid, Shahid Latif, Munera A. Swailem

Saudi Medical Journal

OBJECTIVES: To evaluate the risk factors and physician9s compliance to American College of Chest Physicians (ACCP) guidelines recommendations for venous thromboembolism (VTE) prevention at our hospital. METHODS: This retrospective cohort study was conducted at King Abdulaziz Hospital, Al-Ahsa, Saudi Arabia from November 2009 to December 2009. We used the American College of Chest Physicians (ACCP) 2008 guidelines and Caprini9s scores to assess VTE risk and to determine whether patients had received recommended prophylaxis. All hospital in-patients aged 15 years or above were assessed for risk of VTE by reviewing the hospital chart. A data sheet was developed to obtain the …

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An Infant With Renal And Hepatic Cysts., Mohammed Y. Hasosah, Areej R. Al-Sunaid, Hesham M. Al-Shaalan Nov 2011

An Infant With Renal And Hepatic Cysts., Mohammed Y. Hasosah, Areej R. Al-Sunaid, Hesham M. Al-Shaalan

Saudi Medical Journal

No abstract provided.

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Prevalence Of Igg Antibodies Against Toxoplasma Gondii Among Syrian Females Of Childbearing Age., Mahmood D. Al-Mendalawi, Faraj Barah Nov 2011

Prevalence Of Igg Antibodies Against Toxoplasma Gondii Among Syrian Females Of Childbearing Age., Mahmood D. Al-Mendalawi, Faraj Barah

Saudi Medical Journal

No abstract provided.

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Tragic Rights: The Rights Critique In The Age Of Obama, Robin L. West Nov 2011

Tragic Rights: The Rights Critique In The Age Of Obama, Robin L. West

William & Mary Law Review

No abstract provided.

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Errors Spell Checkers Do Not Correct And Style Sheet, Charles J. Higgins Nov 2011

Errors Spell Checkers Do Not Correct And Style Sheet, Charles J. Higgins

Finance Faculty Works

The article focuses on errors that are not corrected by spell checkers in writing programs and communication devices. It is said that spell checkers may change a written word to an unintended one, as well as may provide autocompletion. A list of words that spell checkers and auto completion programs may confuse is provided. Several words in which writing programs can do little to correct notational styles are also listed.

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Regulating Governmental Data Mining In The United States And Germany: Constitutional Courts, The States, And New Technology, Paul M. Schwartz Nov 2011

Regulating Governmental Data Mining In The United States And Germany: Constitutional Courts, The States, And New Technology, Paul M. Schwartz

William & Mary Law Review

No abstract provided.

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Partisan Conflicts Over Presidential Authority, Jide Nzelibe Nov 2011

Partisan Conflicts Over Presidential Authority, Jide Nzelibe

William & Mary Law Review

No abstract provided.

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