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Work Interrupted: A Questionnaire Assessing The Relationship Between Work-Related Distress And Psychological Adjustment To Cancer, Betsy A. Bates Freed

Antioch University Dissertations & Theses

Cancer is an increasingly survivable disease that significantly impacts the ability of individuals to negotiate successfully the developmental task most distinctly affiliated with middle adulthood: creating meaning through achievement, creativity, and service. For many adults, these goals are accomplished through employment. When cancer intrudes, patients may be deprived of the ability to participate fully in the “generativity” that developmental psychologist Erik Erikson deemed essential to a healthy adulthood. In qualitative studies, patients’ narratives speak of many work-related losses — of routine, normality, economic stability, social connection, purpose, and identity. While psychosocial issues and quality of life are viewed with increasing …

Preliminary Development Of A Q-Sort Measure Of The Adlerian Concept Of Personality Priorities: The Adlerian Personality Priorities Q-Sort (Appqs), Dennis C. Roberts

Antioch University Dissertations & Theses

No abstract provided.

Walking In Two Worlds: Living An Animistic Spiritual Worldview In The Western United States, Joanne Dorpat Halverson

Antioch University Dissertations & Theses

An abundance of culturally derived ideological influences inform our lives. The dominant culture exerts a powerful influence on understandings of reality. For some people, their spiritual way of being in the world deviates from cultural norms. In this qualitative study I sought to understand the lived experience of people who hold an animistic spiritual worldview and yet function well within society. They walk in two worlds. The research design employed both phenomenological and heuristic methods. To understand the socio-cultural-historical context of the study a lengthy background was provided. Six individuals who self-identified as adhering to animistic spirituality living on the …

Integrating Morita Therapy And Art Therapy: An Analysis, Ayako Sato

Antioch University Dissertations & Theses

This study presents therapeutic interventions combining Morita Therapy with art therapy techniques. The author presents literature reviews of art therapy as well as the original Morita Therapy formulated by Shoma Morita, M.D. A new art therapy technique based on the work of Kenji Kitanishi, M.D. (2008) for outpatient treatment is also presented. A case illustration of an eleven‐year‐old Vietnamese‐American boy who presented with high anxiety and school refusal is used as an example of the effective integration of Morita Therapy with art therapy techniques formulated by the author. Even though the boy was not familiar with Morita Therapy principles, the …

The Role Of Nature In John Muir's Conception Of The Good Life, Randy R. Larsen

Antioch University Dissertations & Theses

Aristotle says our best moral guidance comes from considering the lives of exemplary individuals. I explore John Muir, as an exemplar of environmental virtue, and consider the role of Nature in his conception of the good life. I argue his conception consists of a web of virtue including various goods, values, and virtues. I suggest three virtues are cardinal: attentiveness, gratitude and reverence. I explore how Muir cultivated these virtues in Nature.

I argue Muir sought freedom from a popular conception of the good life, grounded in the gilded age values of money and materialism, and was sensitive to the …

Estimating The Efficacy Of Mild Heating Processes Taking Into Account Microbial Non-Linearities: A Case Study On The Thermisation Of A Food Simulant, Vasilis Valdramidis, Brijesh Tiwari, Patrick J. Cullen, Alain Kondjoyan, Jan Van Impe

Articles

Traditional and novel approaches for the calculation of the heat treatment efficiency are compared in this work. The Mild Heat value (MH-value), an alternative approach to the commonly used sterilisation, pasteurisation and cook value (F, P, C–value), is calculated to estimate the efficiency of a mild heat process. MH-value is the time needed to achieve a predefined microbial reduction at a reference temperature and a known thermal resistant constant, z, for log-linear or specific types of non log-linear microbial inactivation kinetics. An illustrative example is given in which microbial inactivation data of Listeria innocua CLIP 20-595 are used for estimating …

Modelling The Effect Of Asparaginase In Reducing Acrylamide Formation In Biscuits, Monica Anese, Barbara Quarta, Jesus Maria Frias

Articles

The influence of asparaginase on acrylamide formation, as well as colour development, in short dough biscuits was studied. In particular, asparaginase concentration, incubation time and temperature were changed according to an experimental design. As acrylamide formation was found to vary significantly between biscuits obtained by using the same ingredients and process, a mixed effect model was used to model variation of acrylamide concentration. By contrast a fixed effect model was used for colour polynomial analysis. Within the range of study, the overall results allowed the best conditions for minimising acrylamide formation to be found. It can be suggested that acrylamide …

Bioactive Potential And Possible Health Effects Of Edible Brown Seaweeds, Shilpi Gupta, Nissreen Abu-Ghannam

Articles

Marine macroalgae (seaweeds) are rich in bioactive compounds that could potentially be exploited as functional ingredients for both human and animal health applications. Despite the intensive efforts that are being made to isolate and identify new compounds with potential medicinal, health or pharmaceutical activities, very few compounds with real potency are available. Bioactive compounds that are most extensively researched include sulfated polysaccharides, phlorotannins and diterpenes. These compounds have been reported to possess strong anti-viral, anti-tumor and anti-cancer properties. At the same time, the prebiotic health potential of the polysaccharides from seaweeds is also increasingly being studied either by feeding whole …

Application Of Principal Component And Hierarchical Cluster Analysis To Classify Different Spices Based On In Vitro Antioxidant Activity And Individual Polyphenolic Antioxidant Compounds, M. Hossain, A. Patras, Catherine Barry-Ryan, Ana Belen Martin-Diana, N. Brunton

Articles

This study investigated the variations in antioxidant profiles between spices using pattern recognition tools; classification was achieved based on the results of global antioxidant activity assays (2,2-diphenyl-1-picrylhydrazyl [DPPH], oxygen radical absorbance capacity [ORAC], ferric reducing antioxidant power [FRAP], microsomal lipid peroxidation [MLP] and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) [ABTS]), levels of different polyphenolic compounds (gallic acid [GA], carnosol [CAR], carnosic acid [CRA], caffeic acid [CA], rosmarinic acid [RA], luteolin-7-O-glucoside [LOG], apigenin-7-O-glucoside [APOG] and total phenols [TP]) of spices namely rosemary, oregano, marjoram, sage, basil, thyme, fennel, celery, cumin and parsley, commonly consumed in Ireland were analyzed. Rosemary showed the highest antioxidant activity measured …

Phenolic Composition, Antioxidant Capacity And Antibacterial Activity Of Selected Irish Brassica Vegetables, Amit Jaiswal, Gaurav Rajauria, Nissreen Abu-Ghannam, Shilpi Gupta

Articles

Vegetables belonging to the Brassicaceae family are rich in polyphenols, flavonoids and glucosinolates, and their hydrolysis products, which may have antibacterial, antioxidant and anticancer properties. In the present study, phenolic composition, antibacterial activity and antioxidant capacity of selected Brassica vegetables, including York cabbage, Brussels sprouts, broccoli and white cabbage were evaluated after extraction with aqueous methanol. Results obtained showed that York cabbage extract had the highest total phenolic content, which was 33.5, followed by 23.6, 20.4 and 18.4 mg GAE/g of dried weight (dw) of the extracts for broccoli, Brussels sprouts and white cabbage, respectively. All the vegetable extracts had …

The Nature Of Relationship Construction And Maintenance For New College Presidents: An Exploratory Study, Mark Allen

Antioch University Dissertations & Theses

The purpose of this study was to explore the nature of relationships within the context of a new college presidency. The college presidency is unique given the societal importance of higher education and the organizational complexity of academia. To remain relevant in addressing society's needs a president must successfully create an environment receptive to self-examination and change. Central to a president's success is the ability to construct and maintain effective relationships. This exploratory research employed a phenomenological approach, interviewing eleven new college presidents as the primary method for gathering data. Through data analysis the researcher captured a deeper understanding of …

Toward A Theoretical View Of Dance Leadership, Jane Morgan Alexandre

Antioch University Dissertations & Theses

This is a theoretical dissertation, creating a beginning understanding of dance leadership.The subject is absent from both the dance and the leadership literature; therefore the concepts have been developed from the experiences of practice and integrated with concepts from those of outside disciplines through the process of reflective synthesis.In order to create this beginning understanding, dance leadership is established herein in its own domain, separate from both dance and leadership.It is a form of informal leadership—that is, not conferred by title or position within an organization—specifically leading in place, practiced by individual or groups of dancers with the goal of …

Mercury Blastn Biosequence Similarity Search System: Technical Reference Guide, Jeremy Buhler

All Computer Science and Engineering Research

This guide documents the operation of the Mercury BLASTN system for hardware-accelerated DNA similarity search. It includes detailed information on the syntax and limitations of the system's component commands, as well as a description of the system's hardware platform suitable for administrators who need to maintain a Mercury BLASTN system. Mercury BLASTN is a product of the High Performance COmputational Biology Group at Washington University.

Joachim Du Bellay's Occasional Poetry: The Poetics Of Female Patronage, Elizabeth Landers

All Theses and Dissertations (ETDs)

This study seeks to demonstrate that female patrons at the Valois court--particularly Marguerite de France, and, to a lesser extent Diane de Poitiers--had a defining influence on both the career and the aesthetic choices of the sixteenth-century French poet Joachim Du Bellay. Although it has often been acknowledged that Du Bellay and Marguerite enjoyed a special relationship, the current study reveals the extent to which Marguerite served as an organizing principal for Du Bellay's entire writing life. As an admired patron, she provided moral support and networking opportunities that encouraged and rewarded Du Bellay's poetic production; her erudition and literary …

Family Policy, Family Resources, And Children's Educational Achievement: A Comparative Study Of 18 Rich Countries, Yung Soo Lee

All Theses and Dissertations (ETDs)

Educational achievement among children is one of the most important concerns for most contemporary societies. While numerous studies have explored factors associated with children's educational achievement, little research fully incorporated multi-level, multi-faceted contexts of child education. More specifically, less attention has been paid to the role of macro-level, policy contexts and their interactions with various aspects of family-level resources. To help fill the gap in the literature, this study investigates: 1) the role of various aspects of family-level resources, that is family financial, human, and social capital, in children's educational achievement,: 2) mediating pathways among those family-level resources, and: 3) …

New Paradigm Of Defibrillation: Towards Painless Therapy, Wenwen Li

All Theses and Dissertations (ETDs)

Sudden cardiac death: SCD) causes approximately 300,000 - 400,000 deaths a year in the United States. It usually starts as ventricular tachycardia: VT) and then degenerates into ventricular fibrillation: VF). Implantable cardioverter defibrillator: ICD) therapy is the only reliable treatment of VT/VF and has been shown to effectively reduce mortality by many clinical trials. However, high-voltage ICD shocks could result in myocardial dysfunction and damage. The majority of patients receiving ICD therapy have a history of coronary disease; their hearts develop myocardium infarction, which could provide a substrate for reentrant tachy-arrhythmias. Other than lethal ventricular tachycardia, atrial fibrillation: AF) became …

The Impacts Of Lead Contamination On The Community Of Herculaneum, Missouri, Jill Mcnew-Birren

All Theses and Dissertations (ETDs)

Lead contamination in Herculaneum, Missouri presents a complex context where the long history of a large lead processing plant has created an environmental health hazard. Local residents have been forced to balance their interest in promoting a clean and healthy local environment against their desire to preserve community identity and honor the history of their city and its most prominent industry. Additionally, contamination and related controversy has substantively impacted this community and its citizens on multiple levels--e. g., education, health, and financial well-being. The study presented in this dissertation explores not only the impact of contamination upon the community, but …

Cardiac Remodeling Of Conduction, Repolarization And Excitation-Contraction Coupling: From Animal Model To Failing Human Heart, Qing Lou

All Theses and Dissertations (ETDs)

Heart failure is one of the leading causes of death worldwide, with rising impact with the increasing ageing population. This is in sharp contrast with the limited and non-ideal therapies available. Approximately 50% of deaths from heart failure are sudden and unexpected, and presumably the consequence of lethal ventricular arrhythmias. Despite significant reduction of mortality from sudden cardiac death achieved by ICDs and drugs such as beta-blockers, there remains a large room for improving the survivability of heart failure patients by advancing our understanding of arrhythmogenesis from molecular level to multi-cellular tissue level. Another important aspect of heart failure is …

Dominant Suppression Of Early Innate Immune Mechanisms By Yersinia Pestis, Paul Price

All Theses and Dissertations (ETDs)

Disease progression of primary pneumonic plague is biphasic, consisting of a pre-inflammatory and a pro-inflammatory phase. Most lung pathogens induce a measureable inflammatory response within a few hours of infection, but Yersinia pestis is strikingly different: the first 36 hours of infection are characterized by rapid bacterial replication in the lung without generating appreciable levels of proinflammatory cytokines/chemokines, histological changes in infected tissue or outward disease symptoms. The ultimate goal of this thesis was to understand the processes that contribute to the pre-inflammatory phase of disease. Upon inhalation of infectious droplets, Y. pestis can interact with a myriad of different …

Strategic Management In Nonprofit Mental Health Service Organizations: Understanding Processes And Impact On Performance, Jennifer Schurer Coldiron

All Theses and Dissertations (ETDs)

Managing the performance of social service-providing nonprofit organizations: NPOs) has become more and more complex in the past few decades as executives have had to cope with increasing competition, demands from a diversified set of stakeholders, rapidly changing technologies, and mounting scrutiny from funders and consumers. To help reduce the complexity of strategic management, organizations have been encouraged to adopt formal strategy formation processes, such as highly-structured strategic planning models. However, there are no demonstrated "best practices" or conclusive evidence of the utility of formal strategy formation within the nonprofit sector. The stakes of mismanagement are high for the organizations …

The Earned Income Tax Credit And Financial Capability Among Native Households, Kristen Wagner

All Theses and Dissertations (ETDs)

EITC refunds are often substantial sums of money entering households of working families each year. Many households use the EITC to meet their basic needs such as rent, utilities, food, groceries, clothing, and other household expenses. Other EITC recipients view the tax system as a savings mechanism. This is the first study of how the EITC is being used among Native populations. Study data includes 9,482 household surveys collected in over 80 urban, rural, and reservation communities across the U.S. Surveys were completed by EITC eligible households, both Native and non-Native in tax years 2005 - 2008. Results from this …

Mechanics Of Heart Tube Formation In The Early Chick Embryo, Victor Varner

All Theses and Dissertations (ETDs)

The heart is the first functioning organ to form in the embryo. For decades, biologists have worked to identify many of the genetic and molecular factors involved in heart development, and over the years, these efforts have helped elucidate the vast biochemical signaling networks, which drive cardiac specification and differentiation in the embryo. Still, the biophysical mechanisms which link these molecular factors to actual, physical changes in cardiac morphology remain unclear. The aim of this thesis is to identify some of the mechanical forces which drive heart tube assembly in the early chick embryo. A unique feature of this work …

Quantitative Perfusion-Sensitive Mri Phantoms, Jeff Anderson

All Theses and Dissertations (ETDs)

Perfusion-sensitive MR methods are increasingly utilized in preclinical and clinical MR research studies with the promise of providing quantitative estimates of parameters that describe in vivo microvasculature. One of these techniques, dynamic contrast enhanced: DCE) MRI, has found particularly common use in oncology for the detection, staging, and monitoring of highly vascularized tumors. DCE-MRI has been qualitatively validated by various studies that show a high correlation between modeled parameters from DCE and histologically measured microvascular density: MVD). However, in the absence of a matching "gold-standard" technique, DCE-MRI has not yet been quantitatively validated: i.e., the accuracy of the estimated parameters …

Atrial Arrhythmogenic Substrates: The Role Of Structure And Molecular Remodeling, Christina Ambrosi

All Theses and Dissertations (ETDs)

Atrial tachyarrhythmias, specifically atrial flutter: AFl) and fibrillation: AF), affect over 2.2 million Americans, leading to more hospitalizations than any other cardiac arrhythmia. These arrhythmias are defined by the presence of reentrant circuits of excitation leading to high atrial rates and uncoordinated activation of the ventricles. The underlying mechanisms of AFl/AF have proven complex and, despite a century of research, no one effective treatment has been developed. Surgical ablation and pharmacological therapies are both fraught with risks and potential pro-arrhythmic side effects. Electrical cardioversion, on the other hand, is extremely effective in terminating these arrhythmias, but the high-energy shocks required …

Lustmord And Loving The Other: A History Of Sexual Murder In Modern Germany And Austria (1873-1932), Amber Aragon-Yoshida

All Theses and Dissertations (ETDs)

Lustmord and Loving the Other: A History of Sexual Murder in Modern Germany and Austria: 1873–1932) examines the historical significance of German–speaking Europeans’ responses to crises of modernity vis–Ã –vis their fin de siècle cultural fascination with crimes and representations of Lustmord. I address the emergence and development of the concept of Lustmord, particularly the changing ways in which medical, legal, and criminal experts, survivors, perpetrators, neighbors, the press, and artists understood and attempted to explain this modern phenomenon. I demonstrate the ways in which a society came to name, understand, and, to some degree, even accept a troubling new …

Development Of Speed, Memory, And Fluid Reasoning In Children, Duneesha De Alwis

All Theses and Dissertations (ETDs)

Children's memory and higher-order cognitive abilities such as fluid reasoning improve with age, but the relationships between these abilities are not well understood. The developmental cascade model proposed by Fry and Hale: 1996) suggests that age related improvements in speed of processing are related to improvements in working memory, which in turn influence fluid reasoning. Recent research in adults suggests secondary memory is also an important predictor of fluid reasoning. The relations between working memory and fluid reasoning have been studied extensively in both adults and children. However, the relationships between working memory, secondary memory, and fluid reasoning have not …

Real-Time Bioluminescence Imaging Of Salmonella-Neoplastic Cell Interactions, Kelly Flentie

All Theses and Dissertations (ETDs)

Salmonella Typhimurium is a Gram-negative bacterial pathogen and a common cause of gastroenteritis in humans. The organism utilizes a multitude of well-studied virulence factors to invade and replicate in host intestinal epithelial cells and macrophages. Interestingly, Salmonella is also capable of localizing to tumors in in vivo model systems, and while the typical route of Salmonella infection and pathogenesis has been thoroughly investigated, the behavior of Salmonella in the tumor microenvironment has not. Therefore, to investigate Salmonella and host behavior during bacterial-neoplastic cell interactions, I utilized two high-throughput screens. In the first, I designed a bioluminescent transposon-reporter trap to identify …

The Hydrology And Geochemistry Of Urban And Rural Watersheds In East-Central Missouri, Elizabeth Hasenmueller

All Theses and Dissertations (ETDs)

This dissertation examines the physical hydrology and geochemistry of surface waters and shallow groundwaters in east-central Missouri, USA, to determine how runoff differs in flow and quality between urban and natural watersheds. The study employs high frequency in situ monitoring of relevant water quality parameters in tandem with lab analyses of major and minor elements and stable isotope concentrations to address degradation of watersheds by land development and other human activities. Chapter 3 of this dissertation compares three watersheds and their tributaries, each with differing levels of urban land use, which were monitored for more than one year to document …

Systematic Identification Of Independent Functional Non-Coding Rna Genes In Oxytricha Trifallax, Seolkyoung Jung

All Theses and Dissertations (ETDs)

Functional noncoding RNAs participate in a variety of biological processes: for example, modulating translation, catalyzing biochemical reactions, sensing environments etc. Independent of conventional approaches such as transcriptomics and computational comparative analysis, we took advantage of the unusual genomic organization of the ciliated unicellular protozoan Oxytricha trifallax to screen for eukaryotic independent functional noncoding RNA genes. The Oxytricha macronuclear genome consists of thousands of gene-sized "nanochromosomes", each of which usually contains only a single gene. Using a draft Oxytricha trifallax genome assembly and a custom-written noncoding nanochromosome classifier, we identified a subset of nanochromosomes that lack any detectable protein coding gene, …

Significance Of Pyuria In The Diagnosis Of Urinary Tract Infections In Neonates, Arshalooz J Rahman, Farah Naz, Sohail Ashraf

Department of Paediatrics and Child Health

OBJECTIVES: To determine the significance of pyuria as a predictor of culture proven urinary tract infections (UTI) in neonates and to assess the frequency of urinary tract anomalies in neonates with pyuria.

METHODS: Prospective study conducted at the neonatal intensive care unit of a tertiary care hospital; (Liaquat National Hospital Karachi) for a period of 4 months from April 2008 to August 2008. One hundred and ten consecutive infants < or = 28 days of age admitted to the NICU of Liaquat National Hospital for medical reasons were included in the study. Information regarding age, gender, antenatal history, birth weight, clinical examination, laboratory findings and outcome were recorded on a questionnaire. Septic work up was performed and urine samples were collected using urethral catheterization. Patients showing any number of white blood cells on microscopy were included and their urine sent for culture. All patients had Ultrasound done during their hospital stay and those patients with any renal abnormality were further investigated with Micturating cyestoretherogram (MCUG) at 6 weeks.

RESULTS: Out of one hundred and ten patients admitted, thirty five patients showed the presence of pus cells in urine and were included in the study. Of the 35 neonates with …