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2011

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Relationships Amongst Chlorella Isolates From The Tropical, Temperate And Antarctic Regions Based On Morphological, Biochemical And Molecular Studies / Shamala Marimuthu, Shamala Marimuthu Jan 2011

Relationships Amongst Chlorella Isolates From The Tropical, Temperate And Antarctic Regions Based On Morphological, Biochemical And Molecular Studies / Shamala Marimuthu, Shamala Marimuthu

Student Works (2010-2019)

Algae from the genus Chlorella are widely distributed on earth, including the Polar Regions. The alga is a model organism for physiology and biochemistry experiments as well as an important organism for biotechnological exploitation. The major objective of this study was to unravel the relationship amongst Chlorella isolates from the Antarctic, sub-Antarctic, tropical and temperate regions based on 18S rDNA sequences as well as morphological and biochemical (fatty acid profiles and pigment composition) features. Eleven isolates of Chlorella, consisting of two Antarctic isolates, one sub–Antarctic isolate, seven tropical isolates and one temperate isolate from the University of Malaya Algae Culture …

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Synthesis Of Bioactive Cyclohexenyl Chalcones And Flavonoid Derivatives / Chee Chin Fei, Chin Fei Chee Jan 2011

Synthesis Of Bioactive Cyclohexenyl Chalcones And Flavonoid Derivatives / Chee Chin Fei, Chin Fei Chee

Student Works (2010-2019)

Flavonoids are a class of natural products that are well known to possess a wide range of pharmacological properties. Due to their recent discovery in modulating muscarinic receptor activity and its inhibitory effect against dengue-2 virus NS3 protease, flavonoids are idea candidates for drug development. This dissertation describes the syntheses of several flavones and some Diels-Alder adducts derived from chalcones. A modified Baker-Venkataraman method has been developed where flavones were prepared in a one-pot procedure from the corresponding 2-hydroxyacetophenones and acyl chlorides under different conditions. When 2-hydroxyacetophenone is heated with a stoichiometric amount of acyl chloride, either in a DBU/pyridine …

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Antioxidant Activity Of Pleurotus Species And Antidiabetic Activity Of Pleurotus Citrinopileatus (Singer) / Rushitha Sadasevevam, Rushitha Sadasevevam Jan 2011

Antioxidant Activity Of Pleurotus Species And Antidiabetic Activity Of Pleurotus Citrinopileatus (Singer) / Rushitha Sadasevevam, Rushitha Sadasevevam

Student Works (2010-2019)

The genus Pleurotus comprises some of the most popular edible mushrooms due to their favourable organoleptic and medicinal properties, vigorous growth and undemanding cultivation conditions. Pleurotus species contain a variety of secondary metabolites including various phenolic compounds which have been said to act as excellent antioxidants and possess antidiabetic activity. The antioxidant activity of mycelial extract of nine Pleurotus species and antidiabetic activity for Pleurotus citrinopileatus was investigated. The total phenolic content in mycelial extract of nine Pleurotus species was assayed by Folin-Ciocalteau’s method while antioxidant activity was determined by two different assays namely scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical …

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Financial Behaviour Under Risk And Uncertainty : Role Of Experience And Emotion / Chak Choy Sim, Choy Sim Chak Jan 2011

Financial Behaviour Under Risk And Uncertainty : Role Of Experience And Emotion / Chak Choy Sim, Choy Sim Chak

Student Works (2010-2019)

In Escherichia coli, the Z ring has the potential to assemble anywhere along the cell length but is restricted to midcell by the action of negative regulatory systems, including Min. In the current model for the Min system, the MinC/MinD division inhibitory complex is evenly distributed on the membrane and can disrupt Z rings anywhere in the cell; however, MinE spatially regulates MinC/MinD by restricting it to the cell poles, thus allowing Z rings formation at midcell. This model assumes that Z rings, formed at different cellular locations have equal sensiticity to MinC/MinD in the absence of MinE. However, there …

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Peranan Institusi Keagamaan Dan Institusi Pengajian Tinggi Awam (Ipta) Dalam Menganalisis Isu Bioetika : Ke Arah Pembentukan Panduan Kapada Pengguna Bioteknologi Di Malaysia / Rasmuna Mazwan Muhammad, Rasmuna Mazwan Muhammad Jan 2011

Peranan Institusi Keagamaan Dan Institusi Pengajian Tinggi Awam (Ipta) Dalam Menganalisis Isu Bioetika : Ke Arah Pembentukan Panduan Kapada Pengguna Bioteknologi Di Malaysia / Rasmuna Mazwan Muhammad, Rasmuna Mazwan Muhammad

Student Works (2010-2019)

Advancements in science and technology particularly in the field of biotechnology and medicine have given rise to various ethical and moral challenges. In Malaysia, these challenges require deliberation which incorporates the scientific and the religious enterprise. This study documents the various processes involved. It shows that bioethics assessment of issues such as genetically-modified food (GMF), the use of porcine enzyme (in livestock), the use of botox, organ transplantation and stem cell treatment is better addressed by the close collaboration of scholars from the Department of Islamic Development Malaysia, the Selangor Mufti Department and the Institute of Islamic Understanding Malaysia with …

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Phytochemical And Biological Activity Study On Pseuduvaria Rugosa (Annonaceae) / Hairin Taha, Taha Hairin Jan 2011

Phytochemical And Biological Activity Study On Pseuduvaria Rugosa (Annonaceae) / Hairin Taha, Taha Hairin

Student Works (2010-2019)

The study of phytochemical constituents on the bark of Pseuduvaria Rugosa from the family Annonaceae has resulted in the isolation and characterization of aporphine alkaloids, benzo[7]annulene and tripenoids. Six aporphine alkaloids have been isolated from the dichloromethane and methanol crude extract of which three of them are new compounds. The known alkaloids were liriodenine 1, ouregidione 5, and Nmethylouregidione 11, whereas the new alkaloids were 3-amino-1,2-dimethoxy-4,5- dioxoaporphine (pseuduvarine A) 36, N-methyl-3-amino-1,2-dimethoxy-4,5- dioxoaporphine (pseuduvarine B) 37 and 3-hydroxy-1,2-dimethoxy-3,4-dioxoaporphine (pseuduvarine C) 38. The aporphine alkaloids with a substituted amino group at position C-3 in ring A have never been discovered in any …

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Mechanical Properties Of Laser Welded Joints In Dissimilar Alloys / Fathi M. Elmabruk, Fathi M. Elmabruk Jan 2011

Mechanical Properties Of Laser Welded Joints In Dissimilar Alloys / Fathi M. Elmabruk, Fathi M. Elmabruk

Student Works (2010-2019)

The objectives of the present study were as follows: (i) to investigate the feasibility of laser welding in fusing a dissimilar joint of cobalt-chromium and titanium metal alloys (ii) to evaluate the properties of the welded joints between cobalt-chromium and titanium alloys. Thirty plastic models of (1×3×42) mm were prepared with conical shoulder shape as following ISO 6871-1dental base metal casting alloys. Models were divided equally into two experimental groups (15 cobalt-chromium and 15 titanium) and one control group of 26 specimens of cobalt-chromium. Each model was invested and moulded into mould rings with a special investment material. The specimens …

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The Comparison Of Protaper And K-Flexofiles In Preparation Of Curved Canals / Chanderan Shanmugam, Chanderan Shanmugam Jan 2011

The Comparison Of Protaper And K-Flexofiles In Preparation Of Curved Canals / Chanderan Shanmugam, Chanderan Shanmugam

Student Works (2010-2019)

OBJECTIVE: To compare the performance of ProTaper® rotary instruments and stainless steel K-Flexofiles in preparing curved root canals in terms of changes in angle of curvature, apical transportation and production of canal aberrations and also to record the rate of separation of ProTaper® files. STUDY DESIGN: Forty-one human mandibular first molars (mesial roots only each with 2 canals) with canal curvature of 15 to 18 degrees were divided into two groups. Forty-one canals were prepared using ProTaper® rotary instruments while forty-one canals were prepared using K-Flexofiles and Gates-Glidden drills. Digital radiographs obtained were analyzed with various image-analyzing programs. The parameters …

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Malocclusion Status And Orthodontic Treatment Needs Of 14-Year Old Yemeni Adolescents / Rasheed Abdul Salam Al-Maqtari, Rasheed Abdul Salam Al-Maqtari Jan 2011

Malocclusion Status And Orthodontic Treatment Needs Of 14-Year Old Yemeni Adolescents / Rasheed Abdul Salam Al-Maqtari, Rasheed Abdul Salam Al-Maqtari

Student Works (2010-2019)

The aim of this study was to develop a national database on the prevalence, severity of malocclusion and orthodontic treatment needs among Yemeni adolescents. Other variables included were geographical zones, gender and urban-rural locations. A multi-stage stratified random sample of 2400 subjects from 60 schools with equal proportion of male and female were selected from nine governorates covering the whole topography of Yemen (coastal, plateau, mountains, desert and islands). Measuring instruments were the conventional FDI/WHO method of occlusal traits (Baume et al., 1973; Berzoukov et al., 1979) and the Index of Orthodontic Treatment Needs (IOTN), (Brooke and Shaw, 1989; Richmond …

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Genetic Diversity Of Plasmodium Falciparum Isolated From Yemen Based On The Genes Of Merozoite Surface Proteins (Msp-1 And Msp-2) / Nazeh Mohammed Al-Abd Ali, Nazeh Mohammed Al-Abd Ali Jan 2011

Genetic Diversity Of Plasmodium Falciparum Isolated From Yemen Based On The Genes Of Merozoite Surface Proteins (Msp-1 And Msp-2) / Nazeh Mohammed Al-Abd Ali, Nazeh Mohammed Al-Abd Ali

Student Works (2010-2019)

Malaria is a major health problem causing substantial morbidity and mortality with Plasmodium falciparum being the causative agent of the most severe and deadly form of malaria in humans. In Yemen Malaria is one of the most serious health problems. About 60% of the populations live in areas with malaria transmission. P. falciparum is the predominant species and accounts for more than 90% of malaria cases. Information on the nature and extent of genetic diversity within P. falciparum is essential for understanding the mechanism underlying the pathology of malaria, the acquisition of immunity, the spread of drug resistance and the …

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The Effects Flooding On House Prices: Two Case Studies In Malaysia / Abdul Mutalib Bin Mohammad Beksin., Abdul Mutalib Mohammad Beksin Jan 2011

The Effects Flooding On House Prices: Two Case Studies In Malaysia / Abdul Mutalib Bin Mohammad Beksin., Abdul Mutalib Mohammad Beksin

Student Works (2010-2019)

Flooding of residential property is a real and growing phenomenon in the Malaysia and is causing short and long-term detriment of various kinds to its victims. The issue of potential decrease in value of those properties which are located on the floodplain, though much discussed in the media, has received scant attention in the Malaysian research literature. An extensive literature survey of Anglo-Saxon and US origin has revealed a need for methodological innovation in the field of temporal impact of flooding and the inadequacy of the current paradigms for inclusion of insurance into flood modelling. The main thrust of this …

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Multiresidue Determination Of Pesticides In Olive And Palm Oil By Lc-Qtof-Ms / Elham Sobhanzadeh, Elham Sobhanzadeh Jan 2011

Multiresidue Determination Of Pesticides In Olive And Palm Oil By Lc-Qtof-Ms / Elham Sobhanzadeh, Elham Sobhanzadeh

Student Works (2010-2019)

In this study a comprehensive evaluation of two efficient sample treatment methods based on LLE/freezing-out coupled with matrix solid-phase dispersion-sonication (UA-MSPD) and precipitation at low temperature followed by dispersive solid-phase extraction (d-SPE) has been performed for determination of dimethoate, malathion, carbaryl, simazine, terbuthylazine, atrazine and diuron in both olive and palm oil using liquid chromatography time-of-flight mass spectrometry (LC-QTOF-MS) and electrospray as the ionization source. Identification and confirmation of the compounds were based on retention time matching along with the accurate mass measurements of the protonated molecules ([M+H]+) and their main fragment ions. Typical electrospray ionization parameters such as nebulizer …

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Self-Healing Polymeric Materials For Potential Dental Application / Sonja Then, Sonja Then Jan 2011

Self-Healing Polymeric Materials For Potential Dental Application / Sonja Then, Sonja Then

Student Works (2010-2019)

Poly(urea-formaldehyde) (PUF) microcapsules that enclose dicyclopentadiene (DCPD) were successfully prepared by in situ polymerization. The effect of diverse process parameters and concentrations of ingredients on the product yield and quality was investigated. After optimizing the procedure high yields of microcapsules were obtained (up to 89%) which appeared in the form of a free-flowing white powder. The morphology of the microcapsules was observed by digital microscopy, optical microscopy (OM), and field emission gun scanning electron microscopy (FESEM). FTIR and 1H-NMR were employed to analyze the chemical structure and content of the core material. The thermal properties were characterized utilizing DSC and …

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Effect Of Plant Growth Regulators On Fruit Growth And Quality Development Of Syzygium Samarangense (Water Apple/Wax Apple) / Adel Mohammed H. Al-Saif, Adel Mohammed H. Al-Saif Jan 2011

Effect Of Plant Growth Regulators On Fruit Growth And Quality Development Of Syzygium Samarangense (Water Apple/Wax Apple) / Adel Mohammed H. Al-Saif, Adel Mohammed H. Al-Saif

Student Works (2010-2019)

The present study was conducted to investigate the effects of Gibberellic Acid (GA3), Naphthalene Acetic Acid (NAA) and N-2-chloro-4-pyridyl-N-phenylurea (CPPU) on the growth and quality development of water apple/ wax apple (Syzygium samarangense). GA3 at the concentrations of 0 (water control) 30, 60 and 90 ppm was used in experiment 1. NAA at the concentrations of 0 (water control), 6, 12 and 18 ppm was used in experiment 2. CPPU at the concentrations of 0 (water control) 10, 15 and 20 ppm was used in experiment 3. The swabbing technique of hormone application was used for all plant growth regulator …

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Physical Properties Of Guanidinium Trifluoromethanesulfonate-Methyldiethanolamine Aqueous Mixtures And Their Co2 Absorption Capacities / Nor Asrina Sairi, Sairi Nor Asrina Jan 2011

Physical Properties Of Guanidinium Trifluoromethanesulfonate-Methyldiethanolamine Aqueous Mixtures And Their Co2 Absorption Capacities / Nor Asrina Sairi, Sairi Nor Asrina

Student Works (2010-2019)

In this work, the physical properties i.e. density, viscosity and CO2 solubility studies were conducted on the aqueous systems of N-methyldiethanolamine (MDEA) and guanidinium trifluoromethanesulfonate [gua][OTf]. The studies were carried out at various concentration of MDEA (1 – 4 M) and [gua][OTf] (0.1 – 2 M). The temperature and pressure were also varied depending on the study involved. The studies on densities and viscosities of binary ([gua][OTf] - H2O) and ternary ([gua][OTf] - MDEA - H2O) systems were carried out at a wide temperature range from 293 to 363 K and at atmospheric pressure. The results show that the density …

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Improvement Of Okra (Abelmoschus Esculentus) Growth, Yield And Qualtiy By Using Plant Growth Regulators In Vivo And In Vitro Conditions / Mekhled Mutiran Alenazi, Mekhled Mutiran Alenazi Jan 2011

Improvement Of Okra (Abelmoschus Esculentus) Growth, Yield And Qualtiy By Using Plant Growth Regulators In Vivo And In Vitro Conditions / Mekhled Mutiran Alenazi, Mekhled Mutiran Alenazi

Student Works (2010-2019)

Studies were conducted to investigate the effects of plant growth regulators on okra growth, yield and quality development using different techniques of application in a commercial vegetable field in Banting, Selangor, Malaysia. The experimental design employed on the commercial field was a randomized complete block design (RCBD). The different growth hormones were applied directly, internally, to the selected parts of the okra plant. In the flower injection treatment, injection was applied on the okra flower using IAA at different concentrations. The pod set percentage, and length was maximal in the 25 mg/l IAA treatment compared to the control. Higher percentage …

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Mycotoxigenic Fungi And Mycotoxins Contaminating Red Rice At Consumer Level In Selangor, Malaysia / Nik Iskandar Putra Samsudin, Samsudin Nik Iskandar Putra Jan 2011

Mycotoxigenic Fungi And Mycotoxins Contaminating Red Rice At Consumer Level In Selangor, Malaysia / Nik Iskandar Putra Samsudin, Samsudin Nik Iskandar Putra

Student Works (2010-2019)

Red rice is a product of rice fermentation by fungi from the genus Monascus notably the M. purpureus, M. ruber, and M. pilosus. Although the traditional method of its preparation does not necessarily adhere to safety and health regulation, it is still widely consumed by Chinese as traditional herbal remedy believed to possess outstanding and diverse industrial, clinical, and food applications. The present study was undertaken to determine the occurrence of mycotoxigenic fungi and mycotoxins present on red rice at consumer level in Selangor, Malaysia. In this study, 50 samples of red rice were obtained from nine administrative districts of …

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Chromosomal Alterations In Oral Cancer For Selected Indian And Indigenous Population / Noor Julieana Mat Amin, Mat Amin Noor Julieana Jan 2011

Chromosomal Alterations In Oral Cancer For Selected Indian And Indigenous Population / Noor Julieana Mat Amin, Mat Amin Noor Julieana

Student Works (2010-2019)

Introduction: In the Malaysian population, the Indians were identified as having a higher oral cancer (OC) risk compared to Malays, Chinese and other ethnicities with betel quid chewing contributing the major factor among Indian female. Cancer progresses through a series of histopathological stages where the progression is thought to be driven by the accumulation of genetic alterations (Garnis et. al., 2009). Therefore, the identification of chromosomal alterations will not only enhance the understanding of the biology in this process, but will also identify important genes that might involve in oral carcinogenesis. Thus, this study utilised array Comparative Genomic Hybridization (arrayCGH) …

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Distributions Of Extractable Organic Compounds In Airborne Paraticulate Matter Over The Straits Of Malacca, South China Sea And Sulu-Sulawesi Seas / Aliaa Diyana Azizuddin, Azizuddin Aliaa Diyana Jan 2011

Distributions Of Extractable Organic Compounds In Airborne Paraticulate Matter Over The Straits Of Malacca, South China Sea And Sulu-Sulawesi Seas / Aliaa Diyana Azizuddin, Azizuddin Aliaa Diyana

Student Works (2010-2019)

The solvent-extractable hydrocarbons of 26 atmospheric samples, collected during a 2 months cruise starting from the Straits of Malacca, South China Sea and ends at Sulu- Sulawesi Seas were analyzed to determine the sources and distributions of homologous compounds series. The atmospheric aerosols were collected using a standard high volume air sampler at the rate of 1.13 m3/min for 24 hours. The filters with suspended particles were then extracted by ultrasonic agitation with dichloromethane and analyzed using gas chromatography-mass spectrometry. The particulate matter contains mainly fatty acids, n-alkanes and low levels of n-alcohols, n-aldehydes and aliphatic ketones derived from both …

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Association Between Interleukin-10 (Il-10) Promoter Polymorphisms And Non Hodgkin Lymphoma In Malaysian Population / Somayeh Fani, Somayeh Fani Jan 2011

Association Between Interleukin-10 (Il-10) Promoter Polymorphisms And Non Hodgkin Lymphoma In Malaysian Population / Somayeh Fani, Somayeh Fani

Student Works (2010-2019)

Non-Hodgkin Lymphoma is one of the malignant diseases that has the most rapidly increasing incidence in many countries. IL10 is a potent cytokine, which has been considered to be involved in pathogenesis of non-Hodgkin lymphoma. Furthermore allelic variations in the genes that has been implicated in inflammation, such as interleukin 10 are candidate risk factors for NHL. This study was been conducted as a case-control experiment on 320 patients with NHL, 285 clinically normal subjects for IL10-1082 G/A SNP and 312 patients with NHL, 284 clinically normal subjects for IL10-819 C/T SNP. After DNA extraction, Polymerase Chain Reaction (PCR) was …

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Association Of Dna Repair Gene Polymorphism (Xrcc1) And Oral Cancer Risk / Mohadeseh Hasanpourghadi, Mohadeseh Hasanpourghadi Jan 2011

Association Of Dna Repair Gene Polymorphism (Xrcc1) And Oral Cancer Risk / Mohadeseh Hasanpourghadi, Mohadeseh Hasanpourghadi

Student Works (2010-2019)

The main aim of the present study was to determine the distribution of XRCC1 Arg399Gln genotypes in oral cancer and non-oral cancer patients. This study was also to investigate the association between XRCC1 Arg399Gln genotypes and oral cancer risk and to compare the distribution of XRCC1 Arg399Gln genotypes among different ethnic groups in Malaysia. This case-control study involved a total of 209 cases of oral squamous cell carcinoma (OSCC) patients and 212 controls with neither any trace of cancers nor any family history of cancer. Mean age of the OSCC patients for cases was 61.34 ± 14.01 years, while for …

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Dna Ploidy In Oral Squamous Cell Carcinoma Among Malaysians / Haki Ismail Ibrahim., Ibrahim Haki Ismail Jan 2011

Dna Ploidy In Oral Squamous Cell Carcinoma Among Malaysians / Haki Ismail Ibrahim., Ibrahim Haki Ismail

Student Works (2010-2019)

Objective: To determine the prevalence of the state of DNA ploidy in OSCC; to compare the state of DNA ploidy between the tumour and its margin; to investigate the association between DNA ploidy status of surgical margins and type of surgical margins; and to investigate the association between the state of DNA ploidy of OSCC and sociodemographic and clinicopathological parameters. Material and method: Specimens (n=78) consisting of paraffin-embedded tissue of OSCC were selected from University of Malaya Oral Pathology Diagnostic Laboratory archives between 2002 to 2009 and peripheral blood monocytes (PBMC) was used as an external control. The cell/nuclear suspensions …

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Association Between Tnf-A-308 G/A Polymorphism And Oral Cancer Risk Among Malaysian Indian And Indigenous / Mojtaba Golpich, Mojtaba Golpich Jan 2011

Association Between Tnf-A-308 G/A Polymorphism And Oral Cancer Risk Among Malaysian Indian And Indigenous / Mojtaba Golpich, Mojtaba Golpich

Student Works (2010-2019)

The primary role of tumor necrosis factor alpha (TNF-α) gene is to regulate immune cells. Dysregulation and, in particular, overproduction of this gene has been found to increase susceptibility to a variety of human diseases such as cancer. The aim of this study is to investigate the association of single nucleotide polymorphism (SNP) in TNF-α −308 promoter and the risk of oral cancer among the Malaysian Indian and Indigenous population.The study included 143 confirmed oral squamous cell carcinoma (OSCC) (mean age = 63.69 ± 12.84) and 79 healthy controls (mean age = 50.43 ± 16.35). The polymerase chain reaction-restriction fragment …

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Coral Ecology Of A Unique Continental Island Of Pulau Perak, Kedah, Malaysia / Affendi Yang Amri, Yang Amri Affendi Jan 2011

Coral Ecology Of A Unique Continental Island Of Pulau Perak, Kedah, Malaysia / Affendi Yang Amri, Yang Amri Affendi

Student Works (2010-2019)

Coral reef research in Peninsular Malaysia has mainly been concentrated on the east coast with little emphasis on the Straits of Malacca (SOM) in the west coast. The coral reefs in SOM are extremely important, more so than their east coast counterparts due to the fact that they are only a few viable coral reef ecosystems in SOM. In the northern part of SOM stands Pulau Perak, an island which has underwater vertical reef walls. Pulau Perak reef walls are unique compared to other continental islands in Peninsular Malaysia which have typical fringing reefs. In addition the scientific knowledge of …

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Screening And Partial Purification Of Protease Inhibitors From Senna Surattensis Leaves / Ahmad Firdhaus Arham., Arham Ahmad Firdhaus Jan 2011

Screening And Partial Purification Of Protease Inhibitors From Senna Surattensis Leaves / Ahmad Firdhaus Arham., Arham Ahmad Firdhaus

Student Works (2010-2019)

This study was done to determine the inhibitory activity that were exhibited by different parts of the local plants in Malaysia selected from the 4 families which are Leguminosae, Rubiaceae, Apocynaceae and Euphorbiaceae. The screening method used in this study are Bradford Assay and Trypsin Inhibitory Assay. Both these assays revealed that Senna surattensis leaves showed the highest inhibitory activity of 83 % compared to other 41 plant samples studied in this study. SDS-PAGE and Tricine SDS on this sample extract showed the presence of this protease inhibitor through the formation of band. From these band also, the molecular weight …

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Analysis Of Transgenic Wild Rice : Molecular Confirmation Of Transgene Presence And Risk Assessment For Pollen Viability / Alireza Saeidi., Alireza Saeidi Jan 2011

Analysis Of Transgenic Wild Rice : Molecular Confirmation Of Transgene Presence And Risk Assessment For Pollen Viability / Alireza Saeidi., Alireza Saeidi

Student Works (2010-2019)

Rice is one of the major sources of food for the population of the world, and almost 50% of the world population depends on it. Malaysian national rice production was estimated to provide just 60-65% of the domestic requirement, so the strategies that can help to increase rice yield are necessary for the agricultural sector of Malaysia. Towards this, one useful research approach is to reduce or knock down expression of a rice gene using RNA interference (RNAi) with the goal of obtaining a phenotype that is suggestive of its function. This project is a based on the analysis of …

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Biological Activities Of Alpinia Pahangensis And Alpinia Mutica Extracts / Fadhlina Binti Mahfot, Mahfot Fadhlina Jan 2011

Biological Activities Of Alpinia Pahangensis And Alpinia Mutica Extracts / Fadhlina Binti Mahfot, Mahfot Fadhlina

Student Works (2010-2019)

The aim of the present study is to investigate the biological activities of two selected wild Alpinia species namely, Alpinia pahangensis Ridl. and Alpinia mutica Roxb. Extraction of the rhizomes and leaves was done successively using three solvents with different polarity: hexane, dichloromethane and methanol. The crude extracts were tested for their antimicrobial and antioxidant activities. The antioxidant activity was determined using the DPPH free radical scavenging method. The antimicrobial activity was investigated based on disc-diffusion assay and minimum inhibition concentration (MIC) against 12 microorganisms consisting of six gram positive bacteria: Bacillus cerues, Bacillus subtilis, Staphylococcus aureus, Streptococus mutans, Streptococcus …

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Terf2 Gene Expression In Childhood Acute Lymphoblastic Leukaemia / Lelamekala Vengidasan, Lelamekala Vengidasan Jan 2011

Terf2 Gene Expression In Childhood Acute Lymphoblastic Leukaemia / Lelamekala Vengidasan, Lelamekala Vengidasan

Student Works (2010-2019)

Advances in the understanding of cell biology in childhood acute lymphoblastic leukemia (cALL) have led to sophisticated risk-stratification based therapeutic interventions targeting individual patients. Despite these advances, approximately 10-20% of children with ALL still relapse. Thus, identification of new prognostic indicators will allow for better targeted treatment. TERF2, one of the main components of the shelterin complex (telosome), has been found to be over-expressed in a variety of epithelial malignancies, including lung, skin and breast cancer. This study aims to investigate the level of expression of TERF2 in pediatric ALL and in different cALL patient subgroups and its potential as …

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Genetic Variation And Differentiation Between Cultured And Wild Populations Of Channa Striata (Haruan) From Microsatellite Markers / Jothi Annavadivoo A/P Balasingam., Jothi Annavadivoo Balasingam Jan 2011

Genetic Variation And Differentiation Between Cultured And Wild Populations Of Channa Striata (Haruan) From Microsatellite Markers / Jothi Annavadivoo A/P Balasingam., Jothi Annavadivoo Balasingam

Student Works (2010-2019)

The snakehead fish (Channa striata) is a freshwater fish species indigenous to Malaysia. Channa striata (C. striata), lo cally known as Haruan is valued as a natural remedy in traditional medicine as well as a reputable source of protein. The rapid progress of scientific validation research on the therapeutic properties of the species has spurred the equally rapid expansion of commercialised products that capitalises on these unique yet beneficial qualities of C. striata. Dependence on the wild in order to meet the increasing demand on the species is no longer a feasible option whereby, deteriorating natural abundance due to anthropogenic …

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Seagrass Mapping And Distribution In Relation To Water Quality Using Gis In Sungai Johor, Peninsular Malaysia / Noor Aini Ahmad, Noor Aini Ahmad Jan 2011

Seagrass Mapping And Distribution In Relation To Water Quality Using Gis In Sungai Johor, Peninsular Malaysia / Noor Aini Ahmad, Noor Aini Ahmad

Student Works (2010-2019)

Seagrass meadows are noted for their extremely high productivity and contribution of valuable ecosystem functions and services to coastal zone. Seagrasses which are vulnerable to the changes of water and environmental quality are increasingly threatened by human activities resulting in a deterioration of water quality. An environmental study on seagrass was conducted at Sungai Johor, Peninsular Malaysia. The purpose of this study was to examine the relationship between species diversity and distribution of seagrasses and various environmental (water quality) factors. Three (3) seagrass species were found along Sungai Johor which identified as Halophila ovalis, Halophila spinulosa and Enhalus acoroides. Halophila …

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