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Prevalence And Risk Of Polypharmacy Among The Elderly In An Outpatient Setting: A Retrospective Cohort Study In The Emilia-Romagna Region, Italy, S. Lane Slabaugh, Vittorio Maio, Megan Templin, Safiya Abouzaid

College of Population Health Faculty Papers

Background: Polypharmacy, the simultaneous taking of many medications, has been well documented and is a topic of much concern for those looking to improve the quality of care for the elderly. Elderly patients often develop complicated and multi-factorial health states that require extensive pharmacotherapy, leaving this population at risk for exposure to drug-drug interactions and other adverse events. Previous literature supports an association between an increase in the rate of adverse events as the number of drugs taken by a patient increases.

Objective: We sought to evaluate the prevalence of polypharmacy, and to determine patient characteristics that are predictive of …

Current And Future Directions In Frailty Research., Anita Mohandas, Joanne Reifsnyder, Mimi Jacobs, Tim Fox

College of Population Health Faculty Papers

The concept of frailty has been evolving dramatically for the past 30 years. Through its evolution, a variety of single and multidimensional models have been used to describe frailty. This article reviews the current literature related to the defining dimensions of frailty and identifies the gaps in the literature requiring additional research. A detailed literature review was performed to identify key dimensions and models currently being used to define frailty, classify interventions that have been developed to reverse frailty, and identify potential areas for future research within this field. Despite the large body of research defining the dimensions of frailty, …

Securing Sovereign State Standing, Katherine Mims Crocker

Faculty Scholarship

There are three main categories of interests upon which states can premise standing to sue as plaintiffs in federal court - proprietary, sovereign, and quasi-sovereign interests. Proprietary and sovereign interests, this Note contends, are held independently by states qua states, whereas quasi-sovereign interests are derivative of citizens’ collective welfare interests. This Note attempts to correct the pervasive confusion clouding the boundary between sovereign and quasi-sovereign interests, arguing that they are meaningfully distinct and should be treated differently.

This argument is especially important in the context of the jurisdictional bar instituted by the Supreme Court in Massachusetts v. Mellon, which prohibits …

Capabilities Perception Of Well-­‐Being And Development Effort: Some Evidence From Afghanistan, Jean-Francois Trani, Parul Bakhshi, Cécile Rolland

Brown School Faculty Publications

This paper examines the relationship between capabilities, well-being and the impact of development efforts in Afghanistan. Using data from a nationally representative survey, we argue that very vulnerable groups maintain a positive perception of well-being by referring to collective values and practices. Our data suggest that deprivation of individual basic capabilities does not systematically lead to a low perception of well-being if individuals have access to other capabilities such as love and care and participation in the community affairs. Nevertheless, access to basic capabilities remains crucial in order to ensure that social norms and expectations cease to constitute constraints and …

Postmortems On The Affordable Care Act (Book Review), Rick Mayes

Political Science Faculty Publications

Nearly two years after the Affordable Care Act became law, books are appearing by Washington insiders who detail how the legislation came about. The two reviewed here discuss and dissect topics related to the health reform law from decidedly different points of view.

Social Network Analysis: A Tool To Improve Understanding Of Collaborative Management Groups, Adam C. Springer, Je De Steiguer

Journal of Extension

Social network analysis (SNA) is a tool used to analyze the connections between people and organizations. However, despite its usefulness to the study of these relations, there have been relatively few applications to situations in agriculture and natural resources. SNA was applied to the study of a watershed collaborative group in southern Arizona. We found that even a fundamental application of SNA was valuable to a watershed initiative and, furthermore, believe that U.S. Extension professionals are positioned to advance the effectiveness of participatory resource management groups through more widespread use of this methodology.

Effects Of Dietary Supplementation Of Conjugated Linoleic Acid In Horses, Shannon Headley

All Theses

Conjugated linoleic acid (CLA) reduces inflammation via the inhibition of cyclooxygenase II , thus reducing prostaglandin E2 (PGE2) production. Conjugated linoleic acid has a suggested osteoclast-suppressive role in bone remodeling and osteoarthritis, which are dependent on bone resorptive stimulator PGE2. Bone resorption marker, deoxypyridinoline (DPD), and bone formation marker, bone alkaline phosphatase (BAP), have been modulated by CLA supplementation in other species. Recent research in equine exercise physiology investigated dietary supplementation of polyunsaturated fatty acids as a possible prevention and treatment for osteoarthritis, but CLA supplementation has putative effects on skeletal function or inflammation in horses has not been reported. …

Temporal Pier Scour Evolution Under Stepped Hydrographs, Mark Schillinger

All Theses

The present study was aimed at measuring the scour hole profile at bridge piers under clear water scour. Scour tests were performed under both steady state flow and under stepped hydrographs. Multiple smaller flood events were run to determine how flood history affects scour hole development. Various equilibrium scour depth equations and proposed temporal scour models were compared. The similarity of the scour hole profiles with time and flow history were evaluated.
Experiments were conducted in a 14.8 m long, 1.19 m wide, 1.22 m deep rectangular flume with a model bridge pier. A uniform sediment bed (d₅₀= …

Modeling Impacts Of Foothills Parkway Construction On Stream Water Quality Using Real-Time Remote Monitoring, Clark Chewning

All Theses

ABSTRACT
The need to monitor surface water quality has been increasingly recognized in recent years in environmental and natural resource management. The advent of real-time remote monitoring technologies has accelerated and enhanced this process. Field observations of water quality data are able to be conducted and analyzed in ways that were previously unavailable.
The objectives of this research were to deploy and test a real-time remote monitoring system for three small watersheds (Hembree, Dunn, and Rudd Hollows) in the Great Smoky Mountains. The watersheds ranged in size from 12 to 19 ha. Real-time remote monitoring stations were established in three …

Robust Design And Monitoring Tools For Sustainable And Resilient Structural Design And Infrastructure Management, Sarah Dalton

All Theses

Structural systems are subject to inherent uncertainties due to the variability in many hard-to-control `noise factors' that include but are not limited to external loads, material properties, and construction workmanship. Two design methodologies have been widely accepted in the practicing engineering realm to manage the variability associated with operational structures: Allowable Stress Design (ASD) and Load and Resistance Factor Design (LRFD). These traditional approaches explicitly recognize the presence of uncertainty; however, they do not take robustness against this uncertainty into consideration. Overlooking this robustness against uncertainty in the structural design process has two drawbacks. First, the design may not satisfy …

Effects Of Larval Exposure To Bacterial Species In Three Genera On Life History Traits And Oviposition Behavior In The Southern House Mosquito, Culex Quinquefasciatus, Jonathan Gravgaard

All Theses

The biofilm is the most common niche for microorganisms living in aquatic environments. Forming a biofilm provides the means to resist shear forces, adverse osmolarity, chemical agents, and other environmental stressors. Biofilms also provide a major food source for aquatic arthropods like mosquito larvae. Culex quinquefasciatus larvae are found in freshwater pools with high organic content, and have the ability to graze on bacterial biofilms. To study how C. quinquefasciatus mosquitoes interact with bacteria in their environment I developed an experimental system that allows mosquito larvae to freely graze on bacteria in either the planktonic or biofilm state. The efficacy …

A Survey And Assessment Of The State Of Low Impact Development In The Berkeley-Charleston-Dorchester County Region Of Coastal South Carolina Emphasizing The Role Of Landscape Architects In Stormwater Management, Noelle Castiglia

All Theses

Watersheds across the U.S., particularly population-dense coastal regions, are being impacted by cultural development preferences which promote an increase in impervious surfaces and ultimately increase the rate and volume of stormwater runoff. Low Impact Development (LID), a site specific form of green infrastructure (GI), is being adopted by many municipalities as an alternative stormwater management solution. Taking advantage of local ecological systems, LID addresses pressing growth requirements with the fundamental need to protect waterways, while also meeting federal regulations resulting from the National Permit Discharge Elimination System (NPDES). This thesis attempts to assess the state of LID in the Berkeley-Charleston-Dorchester …

Quantifying Damages For Lucrum Cessans In Tort: A Fusion Of Sources Creating A Unique Legal Structure For Malta, Fiona Cilia

Journal of Civil Law Studies

No abstract provided.

Can Antioxidant-Rich Berries Improve Risk Factors Associated With Cardiovascular Disease In Postmenopausal Smokers?, Jordan Alaine Teeple

Graduate Theses and Dissertations

The purpose of this study was to examine the effects of smoking on risk factors associated with cardiovascular disease (CVD) and determine the efficacy of antioxidant-rich berries in ameliorating these risk factors in postmenopausal smokers. Menopause and cigarette smoking have been identified as major risk factors for CVD due to a decrease in antioxidant protection, increase in inflammation and oxidative stress, and adverse changes in serum lipids. Antioxidants, specifically flavonoid compounds found in blackberries and blueberries, have been shown to prevent low-density lipoprotein cholesterol oxidation and thus prevent downstream inflammation and oxidative stress. Healthy, postmenopausal nonsmokers (n=14) and smokers (n=31) …

Exploring The Usefulness Of Plastinates In Teaching Anatomy, Ann Kendzicky

Honors Projects

No abstract provided.

Hear My Voice: An Examination Of The Views Of Parents Who Are Raising Children Of African American Descent, Chavez Maurice Phelps

All-Inclusive List of Electronic Theses and Dissertations

Researchers have demonstrated that children who attend early childhood education programs benefit academically and socially (National Institute for Early Education Research, 2003). However, other researchers have shown that African American students may still lag behind their counterparts when they enter school (National Center for Education Statistics ([NCES], 2004). To explain this phenomenon, scholars and practitioners have relied on deficit theories, such as Ruby Payne’s (2005) culture of poverty theory or John Ogbu’s (1992) oppositional culture identity theory, which shift the blame solely on the child or their parents. However, there are other researchers who have stressed the importance of examining …

Effects Of Ectoparasites And Reproductive Class On Roost-Switching And Foraging Behavior Of Indiana Bats (Myotis Sodalis), Nicholas S. Gikas

All-Inclusive List of Electronic Theses and Dissertations

Ectoparasites of bats have been known to cause harm to their hosts and to affect roost-switching. Little research exists on effects ectoparasites may have on roosting and foraging behavior of the federally endangered Indiana bat (Myotis sodalis). From 2008 through 2010, I collected ectoparasite data and documented roost-switching and foraging behavior of Indiana bats on habitat restoration lands owned by the Indianapolis International Airport (IND) in central Indiana. I tested for differences in roosting and foraging behavior between bats with varying ectoparasite loads, and for differences in ectoparasite load, roost-switching frequency, and foraging behavior between different reproductive classes of Indiana …

Optofluidic Glucose Sensor Utilizing An Epoxy-Based, Transparent Dry Film Resist, Zhan Gao, Sijia Gong, Chang Soo Kim, David B. Henthorn

Electrical and Computer Engineering Faculty Research & Creative Works

An enzymatic, fluorescent glucose sensor was constructed with a novel epoxy-Based, optically transparent dry film resist (PerMX 3000 series, DuPont). This material was utilized as the main active material for fluidic structure and optical interrogation. This sensor was based on the enzymatic reaction of glucose oxidase (GOD) and utilized a ruthenium complex fluorophore as the reporting agent. Both the oxygen-sensitive ruthenium complex and GOD were incorporated into poly (ethylene glycol) (PEG)-Based hydrogel materials, which were lithographically patterned and embedded inside the PerMX fluidic channel after wafer-bonding process. the optofluidic sensing platform with this embedded sensing elements exhibited a wide dynamic …

The Significance Of Human Remains In Museum Collections: Implications For Collections Management, Kacey M. Page

History Theses

The significance of a museum collection has changed over the years, in how it is managed and cared for, and how it is viewed by the public. Best practice mandates that professional policies and guidelines be developed to standardize the acquisition, care, and use of all objects or artifacts that are kept within a museum environment. Although human remains are not an exception to these policies, they hold a unique position within museums; standardized guidelines for their care and management are still developing. The following thesis will look into the policies and issues of housing human remains within museums, both …

Method Development And Validation Of The Quantitation Of 19 Antipsychotics Using Deuterated Internal Standards, Anthony S. Epps

Chemistry Theses

Antipsychotic drugs or neuroleptics are used primarily for psychiatric disorders such as schizophrenia, psychosis, and bipolar disorder. In forensic science antipsychotics are drugs of considerable interest because of their potential abuse, involvement in suicides, and they are frequently associated with sudden death investigations. Well-characterized and fully validated analytical data is necessary to generate reproducible and reliable results. As a result, data can be correctly interpreted and objectively demonstrate in its applicability for the intended use. This research has developed and validated a method that is selective, sensitive and accurate using liquid chromatography–tandem mass spectrometry (LC–MS/MS) for the simultaneous determination of …

Alaska Justice Forum ; Vol. 28, No. 4 – Vol. 29 No. 1 (Winter 2012 / Spring 2012), Sharon Chamard, André B. Rosay, Barbara Armstrong

Vols 21-30 (2004-2014)

The Winter/Spring 2012 issue of the Alaska Justice Forum features articles on self-protective behaviors that people engage in to feel safe in their homes, key indicators affecting domestic violence and sexual assault in Alaska, results of an Alaska Judicial Council study of offender recidivism in Alaska, and predicting recidism among Alaska youth offenders.

The Arc Of Justice: Indigenous Activism And Anthropological Intersections, Alaka Wali

Tipití: Journal of the Society for the Anthropology of Lowland South America

This article discusses the intersections between anthropological and Amazonian indigenous activism over a four decade period. It takes the distinctive approach of Shelton "Sandy" Davis as a framework to demonstrate the difficult trajectories of activism for both indigenous peoples and anthropologists. I provide examples from my own experiences working with indigenous organizations in Peru and Ecuador.

Este artículo documenta la intersección entre el activismo de las indígenas amazônicas y antropólogos durante un periodo de cuatro décadas. Uso la perspectiva distincta de Shelton “Sandy” Davis cómo un marco lógico para demonstrar las trayectorias difíciles de activismo. Uso ejemplares de mi propio …

Indigenous Rights And Ethno-Development: The Life Of An Indigenous Organization In The Rio Negro Of Brazil, Janet M. Chernela

Tipití: Journal of the Society for the Anthropology of Lowland South America

Following a successful campaign to end the unlawful practices of trafficking that brought them to Manaus, indigenous Tukanoan women from the Upper Rio Negro established a local indigenous organization with which to plan and manage their own ethno-development, including cultural heritage activities, institution building, revenue development, health and legal services, community, and other initiatives. The case provides an opportunity to explore indigenous ethno-development, a concept at the heart of the theory and practice of Shelton (Sandy) Davis.

No seguimento de uma campanha bem sucessida em Manaus para terminar com práticas de tráfego ilegais, mulheres indígenas da tribo Tukano do Alto …

Firm In The Wind, Jose Barreiro

Tipití: Journal of the Society for the Anthropology of Lowland South America

No abstract provided.

If Not Welfare, Then What?: How Single Mothers Finance College Post-Welfare Reform, Kristin Wilson

The Journal of Sociology & Social Welfare

The article follows previous work on TANF and AFDC by asking if not welfare, then what social programs and financial aid programs are low-income women using to support their college attendance, and what is the impact of these programs on the college-going decisions of low-income women? The study is based on case studies of 10 low-income women attending a community college. Results indicated that EITC, food stamps, and subsidized housing are stable sources of funding. However, each of these programs requires diferent application processes and compliance regulations. Only the Pell Grant was viewed as a dependable source of funding for …

A Critical Edition Of Madison Cawein: Examining The Effects Of Modernism On Regional Poetry, Kristin Teston

Honors Theses

When I first began this project, I had hopes of discovering that long forgotten poet, Madison Cawein, was one of America’s early Modernist writers. However, as time progressed and as I became intimate with Cawein’s work I realized that he was, in fact, not a Modernist. Rather, Cawein’s writing reveals interesting insight on how poets steeped in traditional form were affected by the shift to the Modernist ways thinking and writing. Although, as this project will later reveal, Cawein was much opposed to the free verse style of Modernist writing his concerns about the ever changing modern world closely relate …

Legislative Effects On The Morbidity Rates Of Meningococcal Disease Within The United States, Ashley Brown

Honors Theses

The main focus of this research is to compare the different methods used to control the outbreak of meningococcal disease and determine which one has the greatest effect on the morbidity rates by comparing the number of annual cases before and after the passing of the law. I hypothesize that the variation in state requirements will result in a difference in the incidence of meningococcal disease in each state. I predict that states requiring the vaccine will show a significant decrease in morbidity rates after the passing of the legislation.

Supervisor Self-Disclosure: Supervisees' Experiences And Perspectives, Sarah Knox, Lisa M. Edwards, Shirley A. Hess, Clara E. Hill

College of Education Faculty Research and Publications

Twelve graduate-level supervisees were interviewed regarding their experiences of supervisor self-disclosure (SRSD); data were analyzed using consensual qualitative research. When describing a specific SRSD experience, supervisees reported a range of antecedents (e.g., difficult clinical situation, self-doubt, tension in supervision relationship) followed by supervisor disclosures about clinical experiences or personal information. Supervisees perceived that their supervisors disclosed primarily to normalize, but also to build rapport and to instruct. The SRSDs had mostly positive effects (e.g., normalization), though some negative effects (e.g., deleterious impact on supervision relationship) were reported. Implications of these findings for supervision, training, and research are addressed.

When The State Demands Disclosure, Rebecca Aviel

Cardozo Law Review

The obligation to provide certain types of information to government authorities - reporting child abuse, say, or insurance fraud - is proliferating. Are these laws enforceable against lawyers who obtain the sought-after information in the course of representing a client? This Article sets out to answer exactly that question. It begins by explaining why it is wrong to approach the question by balancing the policies that underlie attorney-client confidentiality against those underlying reporting statutes. Such an approach fails to grasp the essential nature of the question, which is one of legislative power and legislative intent. This Article is the first …

Different Motion Cues Are Used To Estimate Time-To-Arrival For Frontoparallel And Loming Trajectories, Finnegan J. Calabro, Scott A. Beardsley, Lucia M. Vaina

Biomedical Engineering Faculty Research and Publications

Estimation of time-to-arrival for moving objects is critical to obstacle interception and avoidance, as well as to timing actions such as reaching and grasping moving objects. The source of motion information that conveys arrival time varies with the trajectory of the object raising the question of whether multiple context-dependent mechanisms are involved in this computation. To address this question we conducted a series of psychophysical studies to measure observers’ performance on time-to-arrival estimation when object trajectory was specified by angular motion (“gap closure” trajectories in the frontoparallel plane), looming (colliding trajectories, TTC) or both (passage courses, TTP). We measured performance …