Digital Commons Network^™

Postinfectious Cerebellitis: An Unusual Presentation Of Acute Infectious Mononucleosis, Brigid Hallinan Do

Department of Medicine

No abstract provided.

Alternative Regulation Of The Alginate Algd Operon By An Activated Algb In Nonmucoid Pseudomonas Aeruginosa Is Dependent On Sigma 54, Jean Kim

Theses and Dissertations

Alginate overproduction by Pseudomonas aeruginosa, which causes a mucoid phenotype, is a major virulence factor associated with chronic pulmonary infections in cystic fibrosis patients. Expression of the algD operon for alginate biosynthesis requires three major regulators in association with the ECF sigma factor, σ22, in mucoid strains that are typically defective in anti-sigma factor, MucA. One such algD regulator is AlgB, a member of the NtrC family of two-component systems, which typically utilize σ54. However, neither σ54 nor the cognate sensor kinase (KinB) of AlgB are required for algD expression in such mucoid strains. I hypothesized that KinB-phosphorylated AlgB must …

Prediction Of Human Systemic, Biologically Relevant Pharmacokinetic (Pk) Properties Based On Quantitative Structure Pharmacokinetic Relationships (Qspkr) And Interspecies Pharmacokinetic Allometric Scaling (Pk-As), Prajakta Badri

Theses and Dissertations

This research developed validated QSPKR and PK-AS models for predicting human systemic PK properties of three, preselected, pharmacological classes of drugs, namely opioids, β-adrenergic receptor ligands (β-ARL) and β-lactam antibiotics (β-LAs) using pertinent human and animal systemic PK properties (fu,, CLtot, Vdss, fe) and their biologically relevant unbound counterparts from the published literature, followed by an assessment of the effect of different molecular descriptors on these PK properties and on the PK-AS slopes for CLtot and Vdss from two species (rat and dog). Lipophilicity (log (D)7.4) and molecular weight (MW) were found to be the most statistically significant and biologically …

Attributional Style, Presenting Symptoms, And Readiness To Change In Female Childhood Sexual Abuse Survivors, Eric Ford Kebker

Theses and Dissertations

The purpose of this study was to gain a better understanding of the effect that attribution style and presenting symptoms has on the self-reported readiness to change of female survivors of childhood sexual abuse. The aim was to demonstrate that the stages of change are a useful concept in understanding how to approach treatment with female child sexual abuse survivors seeking psychotherapy.

One factor that influences the effectiveness of psychotherapy is a client's degree of motivation. The concept of "stage of change" has been used as a measure of client motivation. Stage of change consists of four basic stages; precontemplative, …

Pre-Employment Screening And Investigation: Navigating Between A Rock And A Hard Place, Stephen F. Befort

Articles

No abstract provided.

A Burkean Perspective On Patent Eligibility, Part Ii: Reflections On The (Counter)Revolution In Patent Law, Thomas F. Cotter

Articles

In 2007, I published an essay in the Berkeley Technology Law Journal, titled A Burkean Perspective on Patent Eligibility, in which I discussed how the United States Court of Appeals for the Federal Circuit and the United States Patent and Trademark Office had discarded various doctrines relating to patent eligibility - among them, rules that all patentable inventions must pertain to the technological arts, that they may not read on mental steps, and that patentable processes must effect a physical transformation - in favor of an approach that asked only whether an invention had practical utility and was predictable in …

The Social, Psychological, And Political Causes Of Racial Disparities In The American Criminal Justice System, Michael Tonry

Articles

No abstract provided.

Apparent Faster-Than-Light Pulse Propagation In Interstellar Space: A New Probe Of The Interstellar Medium, F. A. Jenet, D. Fleckenstein, A. Ford, A. Garcia, R. Miller, J. Rivera, K. Stovall

Physics & Astronomy Faculty Publications

Radio pulsars emit regular bursts of radio radiation that propagate through the interstellar medium (ISM), the tenuous gas and plasma between the stars. Previously known dispersive properties of the ISM cause low-frequency pulses to be delayed in time with respect to high frequency ones. This effect can be explained by the presence of free electrons in the medium. The ISM also contains neutral hydrogen that has a well-known resonance at 1420.4 MHz. Electromagnetic theory predicts that at such a resonance, the induced dispersive effects will be drastically different from those of the free electrons. Pulses traveling through a cloud of …

Triplets Of Supermassive Black Holes: Astrophysics Gravitational Waves And Detection, Pau Amaro-Seoane, Alberto Sesana, Loren Hoffman, Matthew Benacquista, Christoph Eichhorn, Junichiro Makino, Rainer Spurzem

Physics & Astronomy Faculty Publications

Supermassive black holes (SMBHs) found in the centres of many galaxies are understood to play a fundamental, active role in the cosmological structure formation process. In hierarchical formation scenarios, SMBHs are expected to form binaries following the merger of their host galaxies. If these binaries do not coalesce before the merger with a third galaxy, the formation of a black hole triple system is possible. Numerical simulations of the dynamics of triples within galaxy cores exhibit phases of very high eccentricity (as high as e∼ 0.99). During these phases, intense bursts of gravitational radiation can be emitted at orbital periapsis, …

Can Prospective Usability Evaluation Predict Data Errors?, Constance M Johnson, Meredith Nahm, Ryan J Shaw, Ashley Dunham, Kristin Newby, Rowena Dolor, Michelle Smerek, Guilherme Del Fiol, Jiajie Zhang

Faculty, Staff and Student Publications

Increasing amounts of clinical research data are collected by manual data entry into electronic source systems and directly from research subjects. For this manual entered source data, common methods of data cleaning such as post-entry identification and resolution of discrepancies and double data entry are not feasible. However data accuracy rates achieved without these mechanisms may be higher than desired for a particular research use. We evaluated a heuristic usability method for utility as a tool to independently and prospectively identify data collection form questions associated with data errors. The method evaluated had a promising sensitivity of 64% and a …

Sequential Incoherence In A Multi-Party Synchronous Computer Mediated Communication For An Introductory Health Informatics Course, Jorge R Herskovic, J Caleb Goodwin, Pamela A Bozzo Silva, Irmgard Willcockson, Amy Franklin

Faculty, Staff and Student Publications

Online courses will play a key role in the high-volume Informatics education required to train the personnel that will be necessary to fulfill the health IT needs of the country. Online courses can cause feelings of isolation in students. A common way to address these feelings is to hold synchronous online "chats" for students. Conventional chats, however, can be confusing and impose a high extrinsic cognitive load on their participants that hinders the learning process. In this paper we present a qualitative analysis that shows the causes of this high cognitive load and our solution through the use of a …

The Lisa Gravitational Wave Foreground: A Study Of Double White Dwarfs, Ashley J. Ruiter, Krzysztof Belczynski, Matthew Benacquista, Shane L. Larson, Gabriel Williams

Physics & Astronomy Faculty Publications

Double white dwarfs (WDs) are expected to be a source of confusion-limited noise for the future gravitational wave observatory LISA. In a specific frequency range, this \"foreground noise\" is predicted to rise above the instrumental noise and hinder the detection of other types of signals, e.g., gravitational waves arising from stellar-mass objects inspiraling into massive black holes. In many previous studies, only detached populations of compact object binaries have been considered in estimating the LISA gravitational wave foreground signal. Here, we investigate the influence of compact object detached and Roche-Lobe overflow (RLOF) Galactic binaries on the shape and strength of …

Particle Swarm Optimization And Gravitational Wave Data Analysis: Performance On A Binary Inspiral Testbed, Yan Wang, Soumya Mohanty

Physics & Astronomy Faculty Publications

The detection and estimation of gravitational wave signals belonging to a parameterized family of waveforms requires, in general, the numerical maximization of a data-dependent function of the signal parameters. Because of noise in the data, the function to be maximized is often highly multimodal with numerous local maxima. Searching for the global maximum then becomes computationally expensive, which in turn can limit the scientific scope of the search. Stochastic optimization is one possible approach to reducing computational costs in such applications. We report results from a first investigation of the particle swarm optimization method in this context. The method is …

Search For Gravitational Waves From Compact Binary Coalescence In Ligo And Virgo Data From S5 And Vsr1, J. Abadie, B. P. Abbott, Matthew Benacquista, Teviet Creighton, Mario C. Diaz, Soumya Mohanty, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov, Joseph D. Romano

Physics & Astronomy Faculty Publications

We report the results of the first search for gravitational waves from compact binary coalescence using data from the Laser Interferometer Gravitational-Wave Observatory and Virgo detectors. Five months of data were collected during the Laser Interferometer Gravitational-Wave Observatory’s S5 and Virgo’s VSR1 science runs. The search focused on signals from binary mergers with a total mass between 2 and 35M⊙. No gravitational waves are identified. The cumulative 90%-confidence upper limits on the rate of compact binary coalescence are calculated for nonspinning binary neutron stars, black hole-neutron star systems, and binary black holes to be 8.7×10−3  yr−1 L−110, 2.2×10−3  yr−1 L−110, …

The Use Of Dreams In Modern Psychotherapy, Clara E. Hill, Sarah Knox

College of Education Faculty Research and Publications

We review theories of dream work. We also review the empirical research about how dreams are used in psychotherapy, as well as the process and outcome of different models of dream work. Finally, we review how dream content can be used to understand client, the role of culture in dream work, client and therapist dreams about each other, and training therapists to do dream work.

Are We “Reading The World”? A Review Of Multicultural Literature On Globalization, Melissa L. Gibson

College of Education Faculty Research and Publications

Given its commitment to “reading” the social context, how is multicultural education accounting for the shifting context of our globalized world? A conceptual review of multicultural journals reveals limited engagement. However, a more sustained analysis could fuel re-articulations and contestations of the purpose of education in the 21st century.

Who Wants To Be A Muggle? The Diminished Legitimacy Of Law As Magic, Mark Edwin Burge

Faculty Scholarship

In the Harry Potter world, the magical population lives among the non-magical Muggle population, but we Muggles are largely unaware of them. This secrecy is by elaborate design and is necessitated by centuries-old hostility to wizards by the non-magical majority. The reasons behind this hostility, when combined with the similarities between Harry Potter-stylemagic and American law, make Rowling’s novels into a cautionary tale for the legal profession that it not treat law as a magic unknowable to non-lawyers. Comprehensibility — as a self-contained, normative value in the enactment interpretation, and practice of law — is given short-shrift by the legal …

World Views In Peace Building: A Post-Conflict Reconstruction Challenge In Cambodia, Mneesha Gellman

Emerson Authors, Researchers, & Creators

This article explores post-conflict reconstruction in Cambodia through an analysis of both the dangers of liberal peace building and the positive role that training in capacity building plays in war-torn societies. The central question addressed is how insider-outsider dynamics influence Cambodia's post-conflict reconstruction projects; and what assumptions do international workers and Cambodian NGO staff make about 'the good life' that will be constructed? The article offers an overview of Cambodia's history and cultural context to situate its analysis of liberal peace building and foreign donors, as well as the behavioural characteristics of international peace builders operating within Cambodia. It assesses …

Utilizing The School Health Index To Foster University And Community Engagement., Kristi Mcclary King

Faculty and Staff Scholarship

A Coordinated School Health Program maximizes a school’s positive interaction among health education, physical education, health services, nutrition services, counseling/psychological/social services, health school environment, health promotion for staff, and family and community involvement. The purpose of this semester project is for undergraduate health education students to (1) explain the Coordinated School Health Program, (2) assess local schools’ health programs and policies using the School Health Index, (3) develop a School Health Improvement Plan, and (4) present their findings and recommendations for improving their schools’ physical activity, nutrition, tobacco prevention, asthma, and safety policies and programs.

Brief History Of Religion In Northeast Ohio, A, George W. Knepper

Cleveland Memory

This monograph presents a concise but comprehensive look at the history of religion in Northeast Ohio. Starting with the early settlers from New England, Professor Knepper traces the increasingly diverse mixture of faiths that now characterize the life of the sacred in Northeast Ohio. In doing this, Professor Knepper is drawing on a lifetime of study into Ohio's history. Original publication date 2002.

Stained Glass Windows Of Trinity Cathedral, Cleveland, Ohio, Produced By Wilbur H. Burnham Studios, Michael J. Tevesz

Cleveland Memory

Trinity Episcopal Cathedral has over forty large stained glass windows that range in age from the 15 to the 20th Century. The medieval windows were produced in England and Germany, while the more contemporary windows were produced by such prominent studios as those directed by Willet, Connick, Tiffany, Heaton, Young, and Burnham. The more contemporary windows are of considerable artistic and historical interest, but there is very little information available about them. This monograph specifically focuses on the windows of Trinity Cathedral produced by the Wilbur H. Burnham Studios. The Burnham Studios windows are the most accessible windows within the …

Guide To Stones Used For Houses Of Worship In Northeastern Ohio, Joseph T. Hannibal

Cleveland Memory

The purpose of this guide is to serve as an introduction and field guide to the stone used for Northeastern Ohio’s sacred landmarks. compiling this information are noted. Both exterior and interior stones are described. Locations are given so that visitors can find various interior features. Finally, interesting facts having to do with the stones are given in a remarks section and references to sources used. Original publication date 1999.

The Community Arts Council Movement: History, Opinions, Issues, Nina Freedlander Gibans

Cleveland Memory

Initially published in 1982, this book serves as an historical survey of the community arts council movement, as well as an analysis of programs, practices, and trends. Research for the book includes analysis of original source documents from arts councils, as well as discussions with more than 100 members and leaders of arts councils nationwide, including leaders of the National Endowment of the Arts and the American Arts Alliance. Original publication date 1982.

Cleveland : An Inventory Of Historic Engineering And Industrial Sites, Daniel M. Bluestone

Cleveland Memory

"As part of the Office of Archeology and Historic preservation, Department of Interior, the Historic American Engineering Record (HAER) documents historic engineering and industrial sites throughout the Nation. This inventory is the first step in the documentation process." -- from the Introduction

Hart Crane In Akron And Cleveland 1919-1923: Ohio Roads And Bridges To The Bridge, Olivier Alexis

Cleveland Memory

"It is the 1920's. A young poet stands on a bridge at midnight. Below him the river slides black and mysterious, beyond him the lights of the city sparkle. He looks up and raises his arms towards the sky in speechless communion. His fingers 'spread among stars.' He is consumed with the visions which in a few years will culminate in The Bridge. Who might the poet be? Hart Crane, of course. And the bridge and city? The Brooklyn Bridge in New York, right? No, wrong! The bridge is the Detroit- Superior Bridge and the city is Cleveland." — from …

Search For Gravitational-Wave Bursts Associated With Gamma-Ray Bursts Using Data From Ligo Science Run 5 And Virgo Science Run 1, B. P. Abbott, R. Abbott, F. Acernese, Matthew Benacquista, Teviet Creighton, Mario C. Diaz, Soumya Mohanty, Soma Mukherjee, Malik Rakhmanov, Joseph D. Romano

Physics & Astronomy Faculty Publications

We present the results of a search for gravitational-wave bursts (GWBs) associated with 137 gamma-ray bursts (GRBs) that were detected by satellite-based gamma-ray experiments during the fifth LIGO science run and first Virgo science run. The data used in this analysis were collected from 2005 November 4 to 2007 October 1, and most of the GRB triggers were from the Swift satellite. The search uses a coherent network analysis method that takes into account the different locations and orientations of the interferometers at the three LIGO-Virgo sites. We find no evidence for GWB signals associated with this sample of GRBs. …

Supporting University Students With Mental Health Issues: A Needs Assessment, Amanda Celeste Weckwerth

Theses and Dissertations (Comprehensive)

This study was conducted to obtain an understanding of the post-secondary educational experiences of students with mental health issues (MHI’s) at Wilfrid Laurier University (WLU), to examine the needs of these students, to identify specific types of supports and accommodations available to these students, and to determine how improvements could be made by removing any identified barriers and putting in their place needed supports and accommodations. Study components included forming an advisory committee, administering a needs assessment questionnaire to WLU students (n = 78) and a campus service assessment tool to service managers (n = 3), and conducting …

The Influence Of Plantar Cutaneous Stimulation On A Functional Test Of Gait In Parkinson’S Disease, Rachel Van Oostveen

Theses and Dissertations (Comprehensive)

Although possible deficits in proprioception have been implicated as a cause of gait impairments in individuals with Parkinson’s disease (PD), little research has been done to investigate improving this possible deficit as a method to influence mobility. The overall purpose of the current thesis was to investigate the influence of increased plantar stimulation on stability and gait impairments. This study also investigated the contribution of attention to locomotion in PD. The two studies comprising this thesis addressed the possible influence of the ribbed insoles in the initial response of PD participants as well as the long-term use of the insole. …

Identifying Potential Carbon Flux Responses To Shifting Hydroecological And Climactic Regimes In The Peace-Athabasca Delta, Caleb W. Light

Theses and Dissertations (Comprehensive)

The CO2 flux response of organic carbon stored in lake sediments and littoral peat contained in sensitive, northern wetlands may contribute to accelerating atmospheric CO2 concentrations. Temperature and moisture conditions are important variables that affect the rate and quantity of CO2 released to the atmosphere from organic matter stored in lake sediments and peat. Antecedent hydroecological conditions also influence the direction and magnitude of CO2 fluxes to the atmosphere in a changing environment. To better understand and characterize the role of antecedent conditions on CO2 fluxes, this study combines paleolimnological reconstructions with laboratory incubations of littoral peat and lake sediment …

Spiritual Empowerment Through Buddhist Practice, Adam Mckenzie Hodgins

Theses and Dissertations (Comprehensive)

The Buddhist practice of eight Waterloo, Ontario residents are explored in this study, highlighting the relationship between the reported outcomes of Buddhist practice and individual empowerment. By employing a heuristic research methodology, as described by Moustakas (1994), I use my own experience as a Buddhist practitioner to contribute to the research data and elicit detailed descriptions from the participants. The findings of the interviews reveal four common themes of the participants’ Buddhist practice: 1) increased awareness of unconscious habits; 2) peace from letting go of control; 3) a change in their perspective of self; and 4) enhanced connection with others. …