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United Nations Office For Disarmament Affairs, Cisr Journal

The Journal of Conventional Weapons Destruction

The United Nations Office for Disarmament Affairs is one of 14 U.N. bodies or programs that carries out mine action work. UNODA’s work focuses on advising the U.N. Secretary-General’s efforts to fulfill obligations to the Ottawa Convention and the Convention on Certain Conventional Weapons. This article outlines UNODA’s goals, partnerships and recent progress with disarmament efforts, particularly concerning the nonproliferation of SA/LW around the world.

Evaluation Of The Relationship Of Aiouea With Cinnamomum, Ocotea And Mocinnodaphne (Lauraceae) Using Epidermal Leaf Characters, Juan Carlos Penagos Zuluaga

Theses

The relationship of species of Aiouea (Lauraceae) to Cinnamomum, Ocotea, and Mocinnodaphne was evaluated using leaf epidermal characters. Representative species of these genera had been placed in two quite separate clades in a previous molecular study by Chanderbali et al. (2001). This study includes thirty-seven neotropical species of Aiouea, Cinnamomum, Ocotea and Mocinnodaphne. Epidermal characters, including the stomatal apparatus, were observed to evaluate the relationship of Aiouea with the other three genera. Samples were examined under light microscopy and scanning electron microscopy, and characters were scored from digital images. A stomatal rim made by the …

2,4,6-Triphenyl­Aniline, Onome Ugono, Stephanie Cowin, Alicia Beatty

Chemistry & Biochemistry Faculty Works

Individual mol­ecules of the title compound, C24H19N, do not participate in hydrogen-bonding inter­actions due to the steric bulk of the phenyl rings ortho to the amine. The dihedral angles between the central ring and the pendant rings are 68.26 (10), 55.28 (10) and 30.61 (11)°.

Completions 2009-10, Southwestern Oklahoma State University

IPEDS

IPEDS Report on Completions 2009-10

Ciliary Neurotrophic Factor And Its Signal Transduction In The Rat Hypothalamo -Neurohypophysial System, David Y. Lo

Theses and Dissertations

Ciliary neurotrophic factor, a member of the interleukin-6 family of cytokines, promotes neuronal survival and axonal sprouting in various populations of neurons including sensory neurons, motor neurons, and magnocellular neurons (MCN's) of the supraoptic nucleus (SON). Unilateral lesion of the hypothalamo-neurohypophysial tract (HNT) results in an initial period of axonal degeneration followed by a restoration of axonal density in the neurohypophysis by 30 days post-lesion. The restoration of axonal density is attributed to collateral sprouting from MCN's of the intact contralateral SON. A statistically significant increase in CNTF levels was demonstrated previously in the intact contralateral SON following unilateral lesion …

Functional Regulation Of The Transient Receptor Potential Canonical 1 By Caveolin 1 And Stromal Interaction Molecule 1, Biswaranjan Pani

Theses and Dissertations

Caveolae are cholesterol-rich plasma-membrane (PM) microdomains which foster wide-range of signal-transduction events including Ca2+-influx. Caveolae contain Caveolin1 (Cav1) as their major structural-protein. Transient receptor potential canonical 1 (TRPC1) channels constitute an integral-component of store-operated Ca2+ channels (SOCC) which initiate store-operated Ca2+ entry (SOCE), in response to endoplasmic reticulum (ER) Ca2+-store depletion. Recently, Stromal interaction molecule 1 (STIM1) was identified as the ER Ca2+-sensor which, following store-depletion, forms clusters and translocate to peripheral-ER at sub-plasma membrane region and communicates with PM-SOCC activating SOCE. This study identifies a significant role of Cav1 and STIM1 in regulating TRPC1 function. In salivary epithelial cells, …

Trans-4-Hydroxy-2-Hexenal As A Marker Of N-3 Polyunsaturated Fatty Acid Oxidation In Brain In A Rat Model Of Ethanol Withdrawal, Eric K. Long

Theses and Dissertations

Lipid peroxidation is a free radical-mediated process characterized by addition of molecular oxygen to polyunsaturated fatty acids (PUFA). Lipid peroxidation occurs basally, resulting in products that participate in normal signaling. One product is trans-4-hydroxy-2-nonenal (HNE). HNE is a product of lipid peroxidation of n-6 PUFA, such as arachidonic acid, and has the ability to mofify proteins, deplete glutathione, and induce apoptosis. Brain is a tissue that consumes large amounts of oxygen and contains an abundance of PUFA, which suggests a high degree of susceptibility of lipid peroxidation. Lipid peroxidation is known to increase in brain in diseases such as Alzheimer's …

Central Florida Future, Vol. 42 No. 45, July 15, 2010

Central Florida Future

Giving the homeless a voice; Uncover Thursdays; Smokin' aces; Plus: Junk food junkie; Predators review; Health Services redesigns website; Students take service to island locales.

Selenium Determinations, Nanoparticle Sorbent Analysis And Nanoparticle Catalysts For Chemiluminescence, Sandra Grace Hazelton

Theses and Dissertations

Three projects in chemical analysis are presented. In the first, calibration-free Se(IV) determinations were accomplished using an electrochemical flow cell and stripping potentiometry at an unmodified gold electrode. The method was optimized prior to analysis of water and wheat samples. A detection limit of approximately 0.5 ppb Se(IV) was observed. Method accuracy was good and precision was acceptable (%RSD < 10). In the second project, stripping analysis was also employed, this time to analyze metal ion adsorption on carboxylic acid-modified silica nanoparticles. The metals analyzed were Cu(II), Cd(II), and Pb(II). By using anodic stripping voltammetry, adsorbed metal ions could not be detected, thus the need to separate the sorbent from the free metal ions was eliminated. All three metal ions in this study adsorbed in a nearly one-to-one ratio with the carboxylic acid groups at high pH (∼1000 μmol g-1). The effect of pH on adsorption behavior was also investigated. The third project also employed silica nanoparticles and a flow-through detection system. Co(III)-triethanolamine-doped silica nanoparticles were synthesized and used as catalysts for the luminol-H2O2 chemiluminescence reaction. It was found that the chemiluminescent signal increased linearly with the concentration of nanoparticles in bulk solution. The detection limit for the nanoparticles was 1.5 × 10-12 mol L-1 . Luminol-H2O2 chemiluminescence had superior precision when catalyzed by nanoparticles as compared with the free cobalt(III) complex. It was demonstrated that the nanoparticles met the criteria required for a biosensor label.

The Impact Of Social Support On The Neuropsychological Functioning Of Multiple Sclerosis Patients, Caitlin G. Schultz

Theses and Dissertations

Multiple sclerosis is an autoimmune disease which can affect several areas of functioning including physical and psychological functioning. Many individuals experience difficulties with depression and neuropsychological capabilities. Additionally, social networks often appear to be impacted by the disease. Previous research has shown that some of the physical functioning as well as the depressive symptomatology in multiple sclerosis can be ameliorated by improvements in social support. The present study used archival data to explore the impact of social support on neuropsychological function in 112 adults with multiple sclerosis. It was found that higher levels of perceived social support correlated with improved …

Activation Dependent Function Of Transient Receptor Potential Canonical 3 In Neurosecretion, Sunitha Bollimuntha

Theses and Dissertations

Transient receptor potential canonical 3 (TRPC3), a non-selective Ca 2+-permeable cation channel, is a member of the TRP superfamily of ion channels. The mode of activation of TRPC3 is governed by a cascade of Phospholipase C (PLC) mediated signaling events, following G-protein coupled receptor (GPCR) or tyrosine kinase receptor activation, resulting in endoplasmic reticulum (ER) Ca2+ store depletion. This very store depletion triggers the activation of plasma membrane TRPC3 and hence they are termed as receptor operated or store operated cation channels. In addition to the receptor mediated activation of TRPC3, an alternate mode of channel activation has been described, …

Stuck On The Rez: Perceptions Of Native American Students' Experiences In Non-Reservation Schools, Jeffrey Claude Stotts

Theses and Dissertations

The purpose of this qualitative study was to describe perceptions held by Native American students currently residing on a reservation, of the experiences they encountered while attending a non-reservation school. Data for the study was drawn from five participants who attended a high school nearby, but not on, a Native American reservation. Using a phenomenological approach, participants were interviewed three times. The audio recorded interviews were transcribed, coded, and analyzed.Three themes emerged from the data. Theme one: Participants faced numerous challenges stemming from home and school environments. Chief among these were issues related to living on a reservation, and issues …

Fastmedusa: A Parallelized Tool To Infer Gene Regulatory Networks, Serdar Bozdag, Aiguo Li, Stefan Wuchty, Howard A. Fine

Mathematics, Statistics and Computer Science Faculty Research and Publications

Motivation: In order to construct gene regulatory networks of higher organisms from gene expression and promoter sequence data efficiently, we developed FastMEDUSA. In this parallelized version of the regulatory network-modeling tool MEDUSA, expression and sequence data are shared among a user-defined number of processors on a single multi-core machine or cluster. Our results show that FastMEDUSA allows a more efficient utilization of computational resources. While the determination of a regulatory network of brain tumor in Homo sapiens takes 12 days with MEDUSA, FastMEDUSA obtained the same results in 6 h by utilizing 100 processors. Availability: Source code and documentation of …

Frequency Response Of Synthetic Vocal Fold Models With Linear And Nonlinear Material Properties, Stephanie M. Shaw

Theses and Dissertations

Previous studies have shown the importance of cricothyroid muscle activation in altering fundamental frequency in the human voice. Other studies have investigated the non-linear properties of vocal fold tissue and the impact of this non-linearity on frequency response. Several physical models of the vocal folds have been made for research purposes. However, all have been isotropic in nature with linear stress-strain properties. The purpose of this study was to create a physical model with non-linear stress-strain properties to investigate the frequency response of the model as cricothyroid muscle activation was simulated (in other words, as the vocal folds were stretched …

Understanding The Tensions That Exist Between Two Co-Teachers Education Classroom Using Positioning, Garth Gagnier

Theses and Dissertations

The purpose of this study was to explore the tensions that existed between my co-teaching partner and me while working together during the last four years. Additionally, I studied how my partner, the special educator, and I, the general educator, negotiated the tensions that came up during our collaboration. Using a narrative approach to share our stories about our teaching, I investigated how we worked together and contributed to our co-teaching relationship. I analyzed the stories and storylines that we shared using a theoretical lens called positioning. Positioning theory looks at how people interact with each other and the positions …

Genomic Analysis Of Nematode-Environment Interaction, Bishwo Adhikari

Theses and Dissertations

The natural environments of organisms present a multitude of biotic and abiotic challenges that require both short-term ecological and long-term evolutionary responses. Though most environmental response studies have focused on effects at the ecosystem, community and organismal levels, the ultimate controls of these responses are located in the genome of the organism. Soil nematodes are highly responsive to, and display a wide variety of responses to changing environmental conditions, making them ideal models for the study of organismal interactions with their environment. In an attempt to examine responses to environmental stress (desiccation and freezing), genomic level analyses of gene expression …

Division Of Student Affairs 2009-2010 Annual Report, Armstrong Atlantic State University

Armstrong Administration & Governance: Armstrong Student Affairs (Archived)

No abstract provided.

Change In Eating Competence In College Students Enrolled In Basic Nutrition Courses, Katrina J. Larsen

Theses and Dissertations

Objective: Determine change in eating competence (EC) and factors related to EC in students enrolled in basic nutrition courses at a major private university. Design: Eating competence was measured by administering the ecSatter Inventory (ecSI) both before and after class intervention. Additional data on eating disorder prevalence, food security, and general demographics were also collected in the same structured survey. Significance identified with p value <0.01. Setting/Participants: This survey was administered to 566 students enrolled in basic nutrition courses at a major private university in the western United States. Analysis: ANOVA was used to determine relationships between ecSI end scores and participant characteristics. ANCOVA was used to determine relationships between change in ecSI scores over time and participant characteristics. Results: Enrollment in NDFS 100 is associated with an overall increase in eating competence (EC). However, students with current eating disorders had a significant decrease in EC during enrollment. Current or past eating disorders and low or very low Food Security Status were associated with lack of EC. Females and younger participants were not eating competent at the course end. Enrollment in NDFS 201 was not associated with significant change in EC. Conclusions: Basic nutrition instruction improves EC among students without eating disorders. Low food security status and presence of an eating disorder may be a barrier to improving EC.

Gender And Physical Abuse History As Predictors Of Adult Anxiety Reactions To A Public Speaking Evaluative Stress Paradigm, Brian Keith Moe

Theses and Dissertations

Much research has been conducted regarding the long-term effects of childhood maltreatment. Childhood Physical Abuse (CPA), Childhood Sexual Abuse (CSA), and Observed Domestic Abuse (ODA) have been linked to a variety of negative outcomes with effect sizes typically modest in size. This research base has been difficult to interpret because of study differences in the operationalization of abuse and the varied outcome measures that have been employed from study to study. The present study was designed to elicit participant emotional (state/trait anger and anxiety) and physiological (heart rate) reactions to a public speaking stress induction task. A sample of 98 …

Development And Application Of Fluorescent Silica Nanoparticles For Bioanalysis, Yuhui Jin

Theses and Dissertations

In this dissertation, fluorescent silica nanoparticles (NPs) have been successfully developed to improve the performance of bioanalysis. In the first step, the sizes of silica NPs were precisely controlled by changing the organic solvent in the reverse microemulsion method. The size of the NPs can be continuously tuned from 20 to 100 nm. Then, multicolored fluorescent silica NPs were developed with controllable fluorescence properties by manipulating the properties of the dopants. To this end, both the excitation and emission spectra of the dopants could be tuned by conjugating multiple fluorophores through either avidin-biotin linkage or polylysine. With desirable sizes and …

Hippocampal Based Spatial Memory, Antioxidant Defense And Neurogenesis In Long-Living Ames Dwarf Mice, Sunita Sharma

Theses and Dissertations

The US Census Bureau projects that there Will be 71.5 million people over the age of 65 by 2030. One of the most significant problems is that the elderly population suffers from age-associated cognitive impairment. The hippocampus is one identified brain region known to be vulnerable to aging and is associated with a decline in growth hormone/insulin like growth factor-1 (GH/IGF-1), and an increase in oxidative stress and neuronal loss. The Ames dwarf mouse is a long-living animal that is growth hormone deficient and thus, lacks peripheral IGF-1. Ames mice have enhanced antioxidant protection in the peripheral system but the …

Parenting Dimensions And Adolescent Sharing And Concealment, Chelom Eastwood Leavitt

Theses and Dissertations

Given potential risk factors in the lives of adolescents, parents are usually motivated to monitor and protect their adolescents. There is a need to better understand what combinations of parental dimensions and practice best influence an adolescent's propensity to disclose or conceal personal information with their parents. This paper examines how parenting dimensions (warmth, psychological control, and harsh punishment) and the parenting practice of solicitation influence an adolescent's propensity to disclose or conceal information. Adolescents in 106 families (53 females; predominantly Caucasian) reported on their mothers' and fathers' parenting dimensions as well as their parents' effort to solicit information. Factor …

The Inkwell, Armstrong Atlantic State University

The Inkwell

No abstract provided.

Strategies To Employ Androstenediol To Reverse Steroid Inhibited Healing In A Rat Model Of Trauma, Francis Diskin

Theses and Dissertations

Much of our current understanding regarding trauma, mechanisms of healing, and treatment strategies have evolved as a result of injuries suffered during armed conflict. While our understanding of these processes has advanced during and since these conflicts, treatment methods of traumatic wound healing have failed to progress significantly in the last forty years. The overall objective of this research was to test the hypothesis that the immune regulating hormone Androstenediol (AED) modulates the host’s immune system to promote wound healing under conditions where it has been inhibited by stress and infection. In an effort to characterize the effects of Androstenediol …

Re-Connecting: Revitalizing Downtown Clearwater With Environmental Sensibility, Diego Duran

USF Tampa Graduate Theses and Dissertations

Many downtowns in North America have been severed from the rest of the city and from the contextual relationship to their surroundings. Sundered from their context, the ecological characteristics of a site are frequently taken for granted, and the disengagement of its public spaces erodes the downtown's character as well as the urban fabric.

Downtown Clearwater has lost the vitality and vibrancy that once characterized it as a lively district. Because of recent developments in the downtown area, public spaces have been lost between parking lots, high rises and a small number of sporadic residential pockets. Some of the most …

Photothermal Studies Of Carboxymyoglobin, Meagan Small

USF Tampa Graduate Theses and Dissertations

Small ligand diffusion in heme proteins is not fully understood. To help better understand CO diffusion, three systems were investigated: L29H/F43H site-directed sperm whale myoglobin, horse heart myoglobin in a heavy water buffer, and calix[4]resorcinarene. Binding of copper to calix[4]resorcinarene was photophysically characterized to unravel transient binding of small molecules in heme-copper proteins. Copper binding was found to have a low dissociation constant of approximately 8.6 micrometers.. Reaction profiles using photoacoustic calorimetry were constructed for the myoglobin systems. In deuterium oxide, ligand escape is not rate limited by water entry. Large enthalpy differences arise from the thermodynamic properties of deuterium …

Transcription Cofactor Lbh Is A Direct Target Of The Oncogenic Wnt Pathway With An Important Role In Breast Cancer, Megan E. Rieger

Open Access Dissertations

Limb-Bud and Heart (LBH) is a novel key transcriptional regulator of vertebrate development. However, the molecular mechanisms upstream of LBH and its role in adult development are unknown. Here we show that in epithelial development, LBH expression is tightly controlled by Wnt signaling. LBH is transcriptionally induced by the canonical Wnt pathway, as evident by the presence of functional TCF/LEF binding sites in the LBH locus and rapid beta-catenin-dependent upregulation of endogenous LBH by Wnt3a. In contrast, LBH induction by Wnt/beta-catenin signaling is inhibited by Wnt7a, which in limb development signals through a non-canonical pathway involving Lmx1b. Furthermore, we show …

Chemical And Physical Characteristics Of The Sediment In The Pine Barrens Of Central Suffolk County, N.Y., Christine Champey

Long Island Geologists' Abstracts

Additional information on the Long Island Geologists may be found at: http://pbisotopes.ess.sunysb.edu/lig/. Information on the Long Island Association of Professional Geologists may be found at: www.liapg.org. | Long Island Geologists is a program of the Department of Geosciences at Stony Brook University. Each year, the activities include one or two field trips and, on a Saturday in April, a conference on the "Geology of Long Island and Metropolitan New York." Teachers and professional geologists can receive in-service credit for participating in these events. The abstracts contained within this collection are digital representations or copies of papers presented over the years …

Field Guides That Focus On Long Island's Natural Environment, Glenn A. Richard

Long Island Geologists' Abstracts

Additional information on the Long Island Geologists may be found at: http://pbisotopes.ess.sunysb.edu/lig/. Information on the Long Island Association of Professional Geologists may be found at: www.liapg.org. | Long Island Geologists is a program of the Department of Geosciences at Stony Brook University. Each year, the activities include one or two field trips and, on a Saturday in April, a conference on the "Geology of Long Island and Metropolitan New York." Teachers and professional geologists can receive in-service credit for participating in these events. The abstracts contained within this collection are digital representations or copies of papers presented over the years …

Pharmacological And Genetic Reversal Of Age-Dependent Cognitive Deficits Attributable To Decreased Presenilin Function, S. M.J. Mcbride, C. H. Choi, B. P. Schoenfeld, A. J. Bell, D. A. Liebelt, D. Ferreiro, R. J. Choi, P. Hinchey, M. Kollaros, A. M. Terlizzi, N. J. Ferrick, E. Koenigsberg, R. L. Rudominer, A. Sumida, S. Chiorean, Kathleen King Siwicki, H. T. Nguyen, M. E. Fortini, T. V. Mcdonald, T. A. Jongens

Biology Faculty Works

Alzheimer's disease (AD) is the leading cause of cognitive loss and neurodegeneration in the developed world. Although its genetic and environmental causes are not generally known, familial forms of the disease (FAD) are attributable to mutations in a single copy of the Presenilin (PS) and amyloid precursor protein genes. The dominant inheritance pattern of FAD indicates that it may be attributable to gain or change of function mutations. Studies of FAD-linked forms of presenilin (psn) in model organisms, however, indicate that they are loss of function, leading to the possibility that a reduction in PS activity might contribute to FAD …