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Body Lice, Yersinia Pestis Orientalis, And Black Death, Mark Welford, Brian Bossak, Robert G. Mclean, Michael W. Fall, Michel Drancourt, Didier Raoult

United States Department of Agriculture Wildlife Services: Staff Publications

Letters exchanged on role of Y. pestis in European plague Black Death.

Our colleague and mentor David E. Davis researched and wrote in his retirement after years of research and reflection on rat ecology and rodent-borne diseases (3,4). Rattus rattus is commonly recognized as the vertebrate host of fl ea-borne plague that swept through Europe in the 1300s, killing >50% of the population. Davis believed this explanation did not fit what he knew of the ecologic requirements of fleas and black rats. He studied reports of archeologic excavations and reviewed poems, medieval bestiaries, and paintings and concluded that these rats …

Shedding And Serologic Responses Following Primary And Secondary Inoculation Of House Sparrows (Passer Domesticus) And European Starlings (Sturnus Vulgaris) With Low-Pathogenicity Avian Influenza Virus, Nicole M. Nemeth, Nicholas O. Thomas, Darcy S. Orahood, Theodore D. Anderson, Paul T. Oesterle

United States Department of Agriculture Wildlife Services: Staff Publications

Waterfowl and shorebirds are well-recognized natural reservoirs of low-pathogenicity avian influenza viruses (LPAIV); however, little is known about the role of passerines in avian influenza virus ecology. Passerines are abundant, widespread, and commonly come into contact with free-ranging birds as well as captive game birds and poultry. We inoculated and subsequently challenged house sparrows (Passer domesticus) and European starlings (Sturnus vulgaris) with wild-bird origin LPAIV H3N8 to evaluate their potential role in transmission. Oropharyngeal shedding was short lived, and was detected in more starlings (97.2%) than sparrows (47.2%; n = 36 of each). Cloacal shedding was …

Nmr-Based And Automated Docking Characterization Of Protein Structure, Dynamics, And Ligand Binding, Andrew Lawrence Olson

Dissertations (1934 -)

NMR-based methods used in conjunction with a technique called docking are used to characterize ligand binding to proteins. Standard NMR methods were used to study the backbone dynamics of substrate binding to phosphomevalonate kinase (PMK) and it was observed that ligand binding caused PMK to undergo large conformational changes. These changes were reflected by the appearance of many chemical shift changes upon binding of the natural substrates of PMK (both the binary and ternary complexes) in 1H-15N HSQC NMR titration experiments. The same process was used to characterize the effect ligand binding has on the many arginines in the active …

Mojave Applied Ecology Notes Fall 2010, Adria Decorte, Sharon Altman, Alex Suazo

Mojave Applied Ecology Notes

Adria DeCorte defense, Mojave desert inventory and monitoring mapping project, effect of burial depth on Brassica tournefortii seeds

Unlv Magazine, Tony Allen, Shane Bevell, Donna Mcaleer, Ched Whitney, Cate Weeks

UNLV Magazine

No abstract provided.

Women's Research Institute Of Nevada Newsletter, Joanne Goodwin, Women's Research Institute Of Nevada

Newsletters

No abstract provided.

Hrc Enews — 2010 Fall, Megan K. Svarz

Publications (HRC)

This issue contains staff accomplishments and announcements, event listings, and a "new faces" listing for new staff, affiliates, and researchers.

Science And Technology Resources On The Internet: Selected Internet Resources On Digital Research Data Curation, Brian Westra, Marisa Ramirez, Susan Wells Parham, Jeanine Marie Scaramozzino

Library Scholarship

No abstract provided.

Developing A Science Café Program For Your University Library, Jeanine Marie Scaramozzino, Catherine Trujillo

Library Scholarship

The Science Café is a national movement that attempts to foster community dialog and inquiry on scientific topics in informal venues such as coffee houses, bookstores, restaurants and bars. The California Polytechnic State University, San Luis Obispo, Robert E. Kennedy Library staff have taken the Science Café model out of bars and cafes and into the university's library. They have created an outreach opportunity as the campus community comes together to share and discuss faculty research, student work, and outside speakers' knowledge. The Science Café programs encourage open, easy-to-understand conversation exploring scientific and interdisciplinary topics in an attempt to build …

Cooperative Learning And The Gifted Student In Elementary Mathematics, Christine C. Hecox

Doctoral Dissertations and Projects

The research was a quantitative research project dealing with Florida Comprehensive Assessment Test (FCAT) Mathematics scores of fourth grade students, including gifted and high-achieving students, in 2008-2009 under the exposure of daily cooperative learning in mathematics. The problem statement was as follows: In Polk County, Florida, how does cooperative learning affect the FCAT Mathematics scores among fourth grade students, including gifted and high-achieving students? The purpose of the quasi-experimental study was to explore the relationship of cooperative learning versus traditional learning on their student achievement. The null hypothesis was that cooperative learning would have no effect on fourth grade gifted …

A Comparative Analysis Of Factors Influencing The Development Of A Biblical Worldview In Christian Middle-School Students, Cherie Elder Brickhill

Doctoral Dissertations and Projects

One of the important goals of Christian education is to train students to see the world through the lens of scripture. However, Christian schools are regularly graduating students who do not think from a distinctively biblical worldview. This study utilized comparative data analysis (Kruskal-Wallis test) to investigate the relationship between four independent variables and the biblical worldview of middle-school students as measured by the PEERS worldview test. The study examined the influence of type of elementary education, frequency of church attendance, personal faith commitment, and parent Christian belief on the PEERS test scores and religion subcategory scores of students enrolled …

Teacher Perceptions Of Disproportionality Of Minorities In Special Education, Kristy Henry Park

Doctoral Dissertations and Projects

The intent of this study was to determine if special education teachers had certain perceptions regarding the disproportionate amount of minorities in special education classes. I examined special education teachers' awareness of the disproportionality, their causal theories, and the effectiveness of Response to Intervention (RTI) to regulate disproportionality. I implemented three different data collection methods to measure the teachers' perceptions: an initial face-to-face interview session, a written survey, and additional interview questioning. Participants in the study included 11 special education teachers from three middle schools in Northern Georgia. Ten of the 11 teachers admitted awareness of the problem of disproportionality, …

Plankton Community Respiration And Productivity For The Louisiana Offshore Ecosystem, July 2007 Results, Brandon Michael Boyd

Honors Capstones

No abstract provided.

Challenges To Informed Peer Review Matching Algorithms, Matthew Verleger, Heidi Diefes-Dux, Matthew W. Ohland, Mary Besterfield-Sacre, Sean Brophy

Publications

Background Peer review is a beneficial pedagogical tool. Despite the abundance of data instructors often have about their students, most peer review matching is by simple random assignment. In fall 2008, a study was conducted to investigate the impact of an informed algorithmic assignment method, called Un‐weighted Overall Need (UON), in a course involving Model‐Eliciting Activities (MEAs). The algorithm showed no statistically significant impact on the MEA Final Response scores. A study was then conducted to examine the assumptions underlying the algorithm.

Purpose (Hypothesis) This research addressed the question: To what extent do the assumptions used in making informed peer …

Severity And Characteristics Of Developmental Delay Can Be Assessed Using Variability Measures Of Sitting Posture, Anastasia Kyvelidou, Regina T. Harbourne, Nikolaos Stergiou

Journal Articles

Purpose: We sought to identify measures of variability from sitting postural sway that are significantly different among infants who were developing typically, those who were developmentally delayed or hypotonic, and those who later on had a diagnosis of spastic or athetoid cerebral palsy.

Methods: Sixty-five infants were evaluated when they were just developing the ability to sit upright by assessing center of pressure (COP) data, using measures of both amount and temporal organization of COP variability.

Results: The results indicated that measures of variability of COP could discriminate between infants with developmental delay and infants with cerebral palsy and add …

Family Permanence Versus The Best Interests Of The Child, Robert Henley Woody

Psychology Faculty Publications

Historically, promoting family permanence (e.g., keeping the original parent-children relationships intact) has been controversial. At times, priority was given to the family of origin, but due to the best interests of the child principle, there has also been preference for foster placements and adoptions. This article presents the legal backdrop (e.g., the Adoption and Safe Families Act of 1997) and discusses history, as well as ethical and psychological issues. It is asserted that (1) at present, the concept of the best interests of the child is of foremost importance, and (2) biological and psychological parental qualities can be enhanced through …

The Regulation Of Inchoate Technologies, Daniel J. Gervais

Vanderbilt Law School Faculty Publications

In this Essay, I explain why and how certain technologies I refer to as "inchoate" defeat regulatory interventions. I examine the "law" of unintended consequences and the role of regulatory ideologies. I suggest that traditional policymaking models, when applied to inchoate technologies, do not adequately reflect the risk of regulatory failure, which is proportional to the level of inchoateness of the technology. I also consider whether the regulation of inchoate technologies should take into account that, and may in fact be undesirable because, some technologies (or the use thereof) tend to self-regulate. Finally, I suggest lessons that can be drawn …

Intuitions Of Punishment, Owen D. Jones, Robert Kurzban

Vanderbilt Law School Faculty Publications

Recent work reveals, contrary to wide-spread assumptions, remarkably high levels of agreement about how to rank order, by blameworthiness, wrongs that involve physical harms, takings of property, or deception in exchanges. In The Origins of Shared Intuitions of Justice (http://ssrn.com/abstract=952726) we proposed a new explanation for these unexpectedly high levels of agreement.

Elsewhere in this issue, Professors Braman, Kahan, and Hoffman offer a critique of our views, to which we reply here. Our reply clarifies a number of important issues, such as the interconnected roles that culture, variation, and evolutionary processes play in generating intuitions of punishment.

Ecosystem Services And The Clean Water Act: Strategies For Fitting New Science Into Old Law, J.B. Ruhl

Vanderbilt Law School Faculty Publications

This Article explores the administrative reform potential that exists for integrating new knowledge about ecosystem services into Clean Water Act (CWA) regulatory programs as an example for all environmental laws. Part II of the Article reviews the relevant general rules of federal administrative law governing agency interpretation of the policy space available under statutory authority for integrating new science into decision making. Part III then explores the strategies an agency such as EPA can use under those rules to integrate the concept of ecosystem services into regulatory programs by searching for statutory provisions to support what I call "direct protection" …

Sex Lex: Creating A Discourse, Gerald Torres

Cornell Law Faculty Publications

No abstract provided.

4-Phenyl­Sulfon­Yl-2-(P-Tolyl­Sulfon­Yl)-1h,8h-Pyrrolo­[2,3-B]Indole, Jeanese C. Badenock, Jason A. Jordan, Erin T. Pelkey, Gordon W. Gribble, Jerry P. Jasinski

Dartmouth Scholarship

The title compound, C23H18N2O4S2, contains a pyrrolo group fused onto the plane of an indole ring with phenylsulfonyl and p-toluenesulfonyl groups bonded to the indole and pyrrolo rings. The angles between the mean planes of the pyrrolo- indole ring and the phenylsulfonyl and p-toluenesulfonyl rings are 73.7 (6) and 80.6 (0)􏰈, respectively. The dihedral angle between the mean planes of the two benzene rings is 78.7 (4)􏰈. In the crystal, both classical N—H􏰇 􏰇 􏰇O and non-classical C— H􏰇 􏰇 􏰇O intermolecular hydrogen-bonding interactions are observed, as well as weak 􏰁–􏰁 interactions [centroid–centroid distances = 3.6258 (8) and 3.9298 (8) …

Cooperative Interaction Of Transcription Termination Factors With The Rna Polymerase Ii C-Terminal Domain, Bradley M. Lunde, Steve Reichow, Minkyu Kim, Hyunsuk Suh, Thomas C. Leeper, Fan Yang, Hannes Mutschler, Stephen Buratowski, Anton Meinhart, Gabriele Varani

Chemistry Faculty Publications and Presentations

Phosphorylation of the C-terminal domain of RNA polymerase II controls the co-transcriptional assembly of RNA processing and transcription factors. Recruitment relies on conserved CTDinteracting domains that recognize different CTD phosphoisoforms during the transcription cycle, but the molecular basis for their specificity remains unclear. We show that the CTD-interacting domains of two transcription termination factors, Rtt103 and Pcf11, achieve high affinity and specificity both by specifically recognizing the phosphorylated CTD and by cooperatively binding to neighboring CTD repeats. Single amino acid mutations at the protein-protein interface abolish cooperativity and affect recruitment at the 3′-end processing site in vivo. We suggest that …

The Circuit, Fall 2010, Department Of Electrical And Computer Engineering, Michigan Technological University

Department of Electrical and Computer Engineering Newsletters

Table of Contents

• Strategic Faculty Hiring Initiatives at Michigan Tech
• Tech Receives $3 Million to Develop EV Education Programs
• ECE Student Brings Laptops to Ghana
• Tech's Online Power Engineering Program Marks 10th Anniversary
• Dave House: Why Research is Key to the Future of Tech and to ECE
• Alumni Gifts Fund New Center for Computer Systems Research
• Faculty and Student News

Selective Biochlorination Of Hydroxyquinolines By A Flavin-Dependent Halogenase, Fuchao Xu, Amanda Merkley, Dayu Yu, Jixun Zhan

Biological Engineering Faculty Publications

Rdc2 is a flavin-dependent halogenase from Pochonia chlamydosporia. Through the introduction of a His₆-tag to both the N- and C-termini, the isolation yield of Rdc2 from Escherichia coli using Ni-NTA affinity chromatography was increased by three-fold. In vitro reaction of Rdc2 and a flavin reductase (Fre) with seven different hydroxyquinolines revealed that 3-hydroxyquinoline (3), 5-hydroxyquinoline (5), 6-hydroxyquinoline (6), and 7-hydroxyquinoline (7) can be specifically halogenated. These products were prepared by incubating the corresponding substrates with IPTG-induced E. coli BL21(DE3)/Rdc2. They were respectively characterized as 3-hydroxy-4-chloroquinoline (3a), 5-hydroxy-6-chloroquinoline (5a), 5-chloro-6-hydroxyquinoline (6a), and 7-hydroxy-8-chloroquinoline (7a) by NMR and MS …

Growth Of Lactic Acid Bacteria: Influence Of Protocooperation, Bacteriophage Infection, And Prebiotic Carbohydrates, Caitlin D. Goin

School of Biological Sciences: Dissertations, Theses, and Student Research

Lactic acid bacteria are a vital part of the fermented food industry and are the subject of much interest and research. Industry is especially interested in using modern molecular approaches to maintain and improve selected strains; several industrial uses could be improved by closer investigation, namely the protocooperation of S. thermophilus and L. bulgaricus, the role of CRISPRs in phage resistance, and the utilization of prebiotic carbohydrates. Questions such as what genes and pathways are shared during milk fermentation between S. thermophilus and L. bulgaricus, when and what genes are active during bacteriophage infection, and how and where …

A Roadmap Of The Male Brain [Book Review], Lay See Ong Lay See

Research Collection School of Social Sciences

No abstract provided.

Frontier: The Making Of The Northern And Eastern Border In Ladakh From 1834 To The Present, Jonathan M. Deng

Independent Study Project (ISP) Collection

Ladakh, despite popular myths of an isolated Himalayan kingdom, has been a land built on trade and regional connections with India to the south, Tibet to the east, and Central Asia to the north. By participating in these social, political, and economic networks, Ladakh was able to amass a rich collection of cultural influences from many far-flung locales. Historically many of these regional interactions have been defined by the physical terrain, which mountain ranges divided Ladakh from other areas, which passes where open and when they were traversable. Even the political boundaries before the partition of India were loosely defined …

Research Paper Assignment, Andrew Kania

Information Literacy Resources for Curriculum Development

No abstract provided.

Effects Of Experimental Nitrogen Additions On Plant Diversity In An Old-Growth Tropical Forest, Xiankai Lu, Jiangming Mo, Frank S. Gilliam, Guoyi Zhou, Yunting Fang

Biological Sciences Faculty Research

Response of plant biodiversity to increased availability of nitrogen (N) has been investigated in temperate and boreal forests, which are typically N-limited, but little is known in tropical forests. We examined the effects of artificial N additions on plant diversity (species richness, density and cover) of the understory layer in an N saturated old-growth tropical forest in southern China to test the following hypothesis: N additions decrease plant diversity in N saturated tropical forests primarily from N-mediated changes in soil properties. Experimental additions of N were administered at the following levels from July 2003 to July 2008: no addition (Control); …

Comparative Study Of Intravenous Insulin Protocols: Paper-Based Versus Computer-Based, Arleen B. Miller

Nursing Masters

Background: Scientific evidence exists to demonstrate that glycemic control produces a positive outcome for critically ill patients by decreasing mortality and morbidity. Results of published research have revealed a reduction of mortality in critically ill patients when serum blood glucose levels are maintained at a level of less than 150mg/dL. Recommendations from the Surviving Sepsis Campaign for treatment of patients in septic shock include use of intravenous insulin therapy to control hyperglycemia via the use of a validated protocol for insulin dose adjustment. Purpose: The purpose of this study was to determine whether glycemic control (less than 150mg/dL) was attained …