Digital Commons Network^™

Security Council Resolution 1820: An Imperfect But Necessary Resolution To Protect Civilians From Rape In War Zones, Melissa Goldenberg Goldstoff

Cardozo Journal of Equal Rights & Social Justice

The note examines the significance and limitations of UN Security Council Resolution 1820, which recognizes rape as a war crime and a threat to international security. While the Resolution is a crucial step forward in protecting women during armed conflicts, it is argued to be imperfect due to its incomplete implementation mechanisms and potential to undermine earlier resolutions like Resolution 1325, which emphasizes women's roles in peace-building.

Sacred: Religion, Sexuality, And The Law

Cardozo Journal of Equal Rights & Social Justice

Symposium: Sacred: Religion, Sexuality, and the Law (February 9, 2010)

Annotated Legal Bibliography On Gender

Cardozo Journal of Equal Rights & Social Justice

No abstract provided.

Annotated Legal Bibliography On Gender

Cardozo Journal of Equal Rights & Social Justice

No abstract provided.

Citizen Professionals: The Effective Practices Of Experts Helping Community Organizations, Sarah Hippensteel Hall

Antioch University Dissertations & Theses

Although numerous local, state, and federal laws and policies address water pollution, many problems remain. To address these problems thousands of groups of citizens, who are concerned with their water resources - rivers, streams, lakes, ponds, and groundwater - organized around the U.S. over the past several decades. To succeed, these community organizations need the resources and capacity to reach their goals. To gain capacity, some community organizations turn to people outside the organization for assistance. Citizen professionals are helpers who work jointly with an organization to help develop an organization's adaptive capacity to deal with challenges and achieve goals. …

Declamation And Character In The Fletcher-Massinger Plays, John E. Curran Jr.

English Faculty Research and Publications

No abstract provided.

Ecology & Ideology: An Introduction, Gerry Canavan, Lisa Klarr, Ryan Vu

English Faculty Research and Publications

No abstract provided.

Snail Grazing Facilitates Growth Of A Bloom-Forming Alga, Michele Guidone, Carol S. Thornber, Emily Field

Biology Faculty Publications

Herbivory often has a negative effect on plants. However, there is a growing number of examples, primarily in terrestrial ecosystems, where herbivory causes an increase in plant size, growth rate, and/or reproductive output. In marine ecosystems, the positive effects of herbivores on macroalgae are not as well studied, although limited evidence exists for herbivore-induced increases in macroalgal growth rates via 2 mechanisms: nutrient addition via grazer defecation, and epiphyte removal. In this study, we examined the effects of grazing by the mud snail Ilyanassa obsoleta on Ulva lactuca, the dominant bloom-forming macroalga in many New England estuaries. We found …

The Ratio Of Gametophytes To Tetrasporophytes Of Intertidal Chondrus Crispus (Gigartinaceae) Across A Salinity Gradient, Michele Guidone, Sean Grace

Biology Faculty Publications

Population studies of the Gigartinaceae (Rhodophyta) have often observed that the ratio of gametophytes to tetrasporophytes varies with the location of the population or the time of sampling. For some species, patterns have emerged that correlate this ratio to one or a few particular environmental variables, such as elevation, wave exposure, or season. Identifying these distributional patterns is an important step towards understanding what (if any) ecological differences exist between the two free-living life history stages.

The purpose of this study was to measure the ratio of gametophytes to tetrasporophytes of intertidal populations of Chondrus crispus across a decreasing salinity …

Reproductive Behavior In Horseshoe Crabs: Does Density Matter?, Jennifer Mattei, Mark Beekey, Adam Rudman, Alyssa Woronik

Biology Faculty Publications

While the four species of horseshoe crabs share many common reproductive traits with respect to their reproductive systems, they do differ with respect to their mating behavior (monogamy vs. polygynandry). Past research has attributed these differences to a number of factors including: spawning densities, operational sex ratios (OSR’s), male condition (or age), environmental and/or genetic factors, or a combination thereof. Mating behaviors in the three Asian horseshoe crab species (Tachypleus gigas , T. tridentatus, and Carcinoscorpius rotundicauda ) with low spawning densities and 1:1 operational sex ratios are typically monogamous. In Limulus polyphemus , mating behavior is more …

Movement Patterns And Population Genetics Of The American Horseshoe Crab In Relation To Long Island Sound Conservation Strategies, Jo-Marie Kasinak, Kirk A. Bartholomew, Mark Beekey, Jennifer Mattei

Biology Faculty Publications

The Connecticut Department of Environmental Protection (CTDEP) established three no-harvest zones for the horseshoe crab (Limulus polyphemus) population as part of a conservation plan for the species. Data from a long-term mark/recapture study of horseshoe crabs in conjunction with a microsatellite-based genetic survey of the population were analyzed to determine if this plan was appropriate to conserve genetic diversity and broaden our knowledge of movement patterns of Limulus in Long Island Sound (LIS). To date, ~53,000 crabs have been tagged over a 10 year period through the Project Limulus program with an annual average recapture rate of 12 …

A Preliminary Study: Body Dysmorphic Disorder In Division I Women’S Collegiate Soccer Players, Tammy D. Jones

Department of Educational Administration: Dissertations, Theses, and Student Research

The prevalence of Body Dysmorphic Disorder (BDD) among collegiate athletes has not been clearly determined. The purpose of this study was to determine if there are symptoms of body dysmorphic disorder found in Division I women’s soccer players. The researcher hypothesized that there would be some symptoms found within the participants of sport and that there was a need to research this area further.

The study consisted of four participants who participated in semi-structured interviews. The subjects were asked a series of questions from the Yale-Brown Obsessive Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS) to determine if they indicated …

Quantitative Comparison And Modeling Of Urban Storm Water Mass Loadings In The City Of Lincoln, Nebraska, Patrick R. Hartman

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

The main goal of this study is to monitor, and then compare results related to the water quality and mass loadings of several constituents at two sites in Lincoln, Nebraska. Differences in water quality were assessed using matched-pair t-tests. Mass loadings were examined using cumulative mass plots, and a predictive model for total suspended solids (TSS) was developed at both sites using real-time data obtained from a USGS data probe. Statistical comparison tests were conducted on the collected water quality data to detect differences based on sample type (auto vs. grab) and sample location (Taylor Park vs. Colonial Hills) for …

The Globin Gene Family Of The Cephalochordate Amphioxus: Implications For Chordate Globin Evolution, Bettina Ebner, Georgia Panopoulou, Serge N. Vinogradov, Laurent Kiger, Michael C. Marden, Thorsten Burmester, Thomas Hankeln

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

The lancelet amphioxus (Cephalochordata) is a close relative of vertebrates and thus may enhance our understanding of vertebrate gene and genome evolution. In this context, the globins are one of the best studied models for gene family evolution. Previous biochemical studies have demonstrated the presence of an intracellular globin in notochord tissue and myotome of amphioxus, but the corresponding gene has not yet been identified. Genomic resources of Branchiostoma floridae now facilitate the identification, experimental confirmation and molecular evolutionary analysis of its globin gene repertoire.

Results

We show that B. floridae harbors at least fifteen paralogous globin genes, …

Mapping Haplotype-Haplotype Interactions With Adaptive Lasso, Ming Li, Roberto Romero, Wenjiang J. Fu, Yuehua Cui

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

The genetic etiology of complex diseases in human has been commonly viewed as a complex process involving both genetic and environmental factors functioning in a complicated manner. Quite often the interactions among genetic variants play major roles in determining the susceptibility of an individual to a particular disease. Statistical methods for modeling interactions underlying complex diseases between single genetic variants (e.g. single nucleotide polymorphisms or SNPs) have been extensively studied. Recently, haplotype-based analysis has gained its popularity among genetic association studies. When multiple sequence or haplotype interactions are involved in determining an individual's susceptibility to a disease, it …

Novel Cis-Trans Interactions Are Involved In Post-Transcriptional Regulation Of Cyclin-Dependent Kinase Inhibitor P21Waf1/Cip1 Mrna, Liyue Zhang, Anil Wali, Joseph A. Fontana, Marcia I. Dawson, Arun K. Rishi

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

A variety of pathways target CDKI p21^WAF1/CIP1 expression at transcriptional, post-transcriptional as well as translational levels. We previously found that cell growth suppressing retinoid CD437 enhanced expression of p21^WAF1/CIP1 and DNA damage inducible GADD45 proteins in part by elevating their mRNA stability.

Results

Here, we investigated molecular mechanisms of CD437-dependent post-transcriptional regulation of p21^WAF1/CIP1 expression. By utilizing MDA-MB-468 HBC cells expressing chimeric rabbit β-globin-p21^WAF1/CIP1 transcripts we mapped multiple CD437-responsive sequences located within positions 1195 to 1795 of the 3'-untranslated region of p21^WAF1/CIP1 mRNA. Several cytoplasmic proteins present in MDA-MB-468, MCF-7 HBC as well …

Comparison Of Mitotic Cell Death By Chromosome Fragmentation To Premature Chromosome Condensation, Joshua B. Stevens, Batoul Y. Abdallah, Sarah M. Regan, Guo Liu, Steven W. Bremer, Christine J. Ye, Henry H. Heng

Wayne State University Associated BioMed Central Scholarship

Abstract

Mitotic cell death is an important form of cell death, particularly in cancer. Chromosome fragmentation is a major form of mitotic cell death which is identifiable during common cytogenetic analysis by its unique phenotype of progressively degraded chromosomes. This morphology however, can appear similar to the morphology of premature chromosome condensation (PCC) and thus, PCC has been at times confused with chromosome fragmentation. In this analysis the phenomena of chromosome fragmentation and PCC are reviewed and their similarities and differences are discussed in order to facilitate differentiation of the similar morphologies. Furthermore, chromosome pulverization, which has been used almost …

Molecular And Therapeutic Implications Of Notch1 Signaling In Pediatric T-Cell Acute Lymphoblastic Leukemia, Amanda Larson Gedman

Wayne State University Dissertations

T-cell acute lymphoblastic leukemia (T-ALL) accounts for 15% of pediatric ALL cases and is associated with early relapse and inferior outcome. The poorer prognosis of T-ALL compared to B-precursor ALL may in part reflect the lack of unique features on which to base therapy. NOTCH1 mutations are of particular interest since these were reported in 37-71% of T-ALLs. The prognostic value of NOTCH1 mutations remains controversial as both favorable and unfavorable associations were reported, whereas in other studies, there were no associations between NOTCH1 mutations and treatment outcome. We explored the impact of mutations in NOTCH1, FBW7 and PTEN on …

Matriptase/Pdgf D/Beta-Pdgfr Signaling Axis In Human Prostate Cancer: The Role Of Pten In The Regulation Of Pdgf D Expression, M. Katie Conley-Lacomb

Wayne State University Dissertations

Platelet Derived Growth Factor (PDGF) is a family of mesenchymal growth factors that regulate cell proliferation, migration, and differentiation. Unlike the classic PDGF ligands A and B, which are secreted as active dimers, PDGF D must undergo extracellular proteolytic processing to remove its N-terminal CUB domain from the C-terminal PDGF growth domain before the ligand is able to stimulate its receptor, PDGF receptor beta (?-PDGFR). Importantly, recent clinical studies have shown that ?-PDGFR is upregulated in primary prostate cancer and bone metastases. However, PDGF B, formerly thought to be the sole ligand for ?-PDGFR, is not expressed in clinical prostate …

The Growing Need For A Unified Biopsychosocial Approach In Mental Health Care, Timothy Melchert

College of Education Faculty Research and Publications

Psychology has been remarkably successful as a scientific discipline and field of clinical practice. Despite its remarkable growth, however, the field has also experienced substantial conflict and controversy. There has been great diversity in the approaches counselors and psychologists have used to understand development, psychopathology, and the goals and processes of psychotherapy. This has led to large numbers of conflicts and controversies that have distracted the field from its primary purposes. A biopsychosocial approach has the potential to bring the field together around a unified science-based framework for understanding mental health practice that will avoid these conflicts.

From The Bottle To The Grave: Realizing A Human Right To Breastfeeding Through Global Health Policy, Benjamin Mason Meier, Miriam Labbok

Case Western Reserve Law Review

No abstract provided.

Work-Family Conflict In Work Groups: Social Information Processing, Support, And Demographic Dissimilarity, Devasheesh P. Bhave, Amit Kramer, Theresa G. Glomb

Research Collection Lee Kong Chian School Of Business

We used social information processing theory to examine the effect of work-family conflict (WFC) at the work group level on individuals' experience of WFC. Consistent with hypotheses, results suggest that WFC at the work group level influences individual WFC over and above the shared work environment and job demands. It was also observed that work group support and demographic dissimilarity moderate this relationship. Moderator analyses suggest that work group social support buffers WFC for individuals but is also associated with a stronger effect of work group WFC on individuals' WFC. Moreover, the work group effect on individuals' WFC was shown …

Educational Institution Reform: Insights From The Complexity-Intelligence Strategy, Pak Tee Ng, Thow Yick Liang

Research Collection Lee Kong Chian School Of Business

This paper attempts to draw some significant insights for educational institution reform from the paradigm of organizing around intelligence. Using the Complexity-Intelligence strategy, human organizations are visualized as intelligent beings possessing an orgmind with high collective intelligence, and other intelligence-related characteristics that are commonly found in highly intelligent biological beings including consciousness, complex adaptive dynamic, autopoiesis, self-organization, learning, adaptation and emergence. Such intelligent human organizations primarily focus on quality connection, optimizing the intrinsic intelligence sources, and nurturing a high level of collective intelligence. It is a living intelligence-centric world. In this study, four insights and their implications from the Complexity-Intelligence …

State Of The Fisheries And Aquatic Resources Report 2009/10, W.J Fletcher, K. Santoro

Status Reports of the Fisheries and Aquatic Resources

As outlined in the CEO’s overview, this year’s renamed State of the Fisheries and Aquatic Resources Report 2009/10 reflects that the Department of Fisheries has now fully adopted an Ecosystem Based Fisheries Management (EBFM) framework as the basis for management of Western Australia’s aquatic resources (Fletcher, et al., 20101). Consequently, the format for this document has been updated so that it is consistent with this risk-based approach to resource management.

Non-Invasive Brain Stimulation Techniques For Chronic Pain In Adults, Neil E. O'Connell, Benedict M. Wand, Louise Marston, Sally Spencer, Lorraine H. De Souza

Health Sciences Papers and Journal Articles

Description of the condition: Chronic pain is a common problem. When defined as pain of greater than three months duration, prevalence studies indicate that up to half the adult population suffer from chronic pain, and 10 to 20% experience clinically significant chronic pain (Smith 2008). In Europe 19% of adults experience chronic pain of moderate to severe intensity with serious negative implications for their social and working lives and many of these receive inadequate pain management (Breivik 2006). Chronic pain is a heterogenous phenomenon that results from a wide variety of pathologies including chronic tissue injury such as arthritis, peripheral …

Body Mass Index, Adiposity Rebound And Early Feeding In A Longitudinal Cohort (Raine Study), Paola Chivers, Beth P. Hands, Helen Parker, Max K. Bulsara, Lawrence Beilin, Garth Kendall, Wendy Oddy

Health Sciences Papers and Journal Articles

Objective: This study examined the influence of type and duration of infant feeding on adiposity rebound and the tracking of body mass index (BMI) from birth to 14 years.

Methods: A sample of 1330 individuals over eight follows-ups was drawn from the Western Australian Pregnancy Cohort (Raine) Study. Trajectories of BMI from birth to adolescence using linear mixed model (LMM) analysis investigated the influence of age breastfeeding stopped and age other milk introduced (binomial 4-month cut-point). A sub-sample of LMM predicted BMI was used to determine BMI and age at nadir for early infant feeding groups.

Results: Chi square analysis …

A Cell Autonomous Role For The Notch Ligand Delta-Like 3 In Αβ T- Cell Development, Gerard F. Hoyne, Gavin Chapman, Yovina Sontani, Sharon E. Pursglove, Sally L. Dunwoodie

Health Sciences Papers and Journal Articles

Notch signalling is critical to help direct T-cell lineage commitment in early T-cell progenitors and in the development of αβ T-cells. Epithelial and stromal cell populations in the thymus express the Notch DSL (Delta, Serrate and Lag2) ligands Delta-like 1 (Dll1), Delta-like 4 (Dll4), Jagged 1 and Jagged 2, and induce Notch signalling in thymocytes that express the Notch receptor. At present there is nothing known about the role of the Delta-like 3 (Dll3) ligand in the immune system. Here we describe a novel cell autonomous role for Dll3 in αβ T-cell development. We show that Dll3 cannot activate Notch …

A Comparison Of Field Measures Of Adiposity Among Australian Adolescents From The Raine Study, Paola Chivers, Helen Parker, Beth P. Hands, Lawrence Beilin, Garth Kendall, Max Bulsara

Health Sciences Papers and Journal Articles

This study examined the possible inter-changeability of common proxy measures of adiposity in adolescent 14 year olds from a large cohort. A sample of 1,607 adolescents (n=825 male and n=782 female) was drawn from the Western Australian Pregnancy Cohort (Raine) Study. Pearson Product Moment Correlation, Bland-Altman method, and Bland regression were used to determine the level of agreement between common proxy adiposity measures. The Bland-Altman and Bland regression results supported the notion that the two indices (Waist-height-Ratio and Body-Mass-Index) are measuring a similar construct (F = .974, p = .324). However 95 percent limits of agreement differed between the methods …

Importance Of Contact Chemical Cues In Host Recognition And Acceptance By The Braconid Larval Endoparasitoids Cotesia Sesamiae And Cotesia Flavipes, Meshack Obonyo, Fritz Schulthess, Bruno Le Ru, Johnnie Van Den Berg, Jean François Silvain, Paul André Calatayud

All Peer-Reviewed Publications

The ability of the congeneric braconid parasitoids Cotesia sesamiae (Cameron) and Cotesia flavipes Cameron to discriminate between stemborer larval cues upon contact was studied using their natural hosts, namely the noctuid Busseola fusca (Fuller) and the crambid Chilo partellus (Swinhoe), respectively, and the pyralid non-host Eldana saccharina (Walker). When the natural host larvae were washed in distilled water, parasitoid behavior was similar to that displayed when in contact with E. saccharina, characterized by the absence of ovipositor insertion. When washed host or non-host larvae were bathed with water extracts of their natural host, the parasitoids showed a significant increase in …

Geographic And Breed Distribution Patterns Of An A/G Polymorphism Present In The Mx Gene Suggests Balanced Selection In Village Chickens, S. Ommeh, L. N. Jin, H. Eding, F. C. Muchadeyi, S. Sulandari, M. S.A. Zein, G. Danbaro, C. E. Wani, S. G. Zhao, Q. H. Nie, X. Q. Zhang, M. Ndila, R. Preisinger, G. H. Chen, I. A. Yousif, K. N. Heo, S. J. Oh, M. Tapio, D. Masiga, O. Hanotte, H. Jianlin, S. Weigend

All Peer-Reviewed Publications

An A/G Single Nucleotide Polymorphism (SNP) at position 1,892 of the Mx gene coding sequence has been linked to susceptibility/resistance to avian viral infection in vitro. Using PCR-RFLP and sequencing methods, 1,946 samples from 109 populations from Asia, Africa and Europe; grouped as indigenous village, commercial, fancy chicken as well as wild junglefowl were genotyped for the polymorphism. Allele and genotype frequencies were calculated. Only the G allele was present in Ceylon junglefowl Gallus lafayetti. Using the wild red junglefowl G. gallus population as reference, we assessed if the A/G alleles and genotypes frequencies have been affected by the breeding …