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2010

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Chromium(Iii/Vi) Binding To Magnetite (Fe3o4), Hausmannite (Mn3o4), And Jacobsite (Mnfe2o4) Nanomaterials, Jeffrey Edward Hernandez Jan 2010

Chromium(Iii/Vi) Binding To Magnetite (Fe3o4), Hausmannite (Mn3o4), And Jacobsite (Mnfe2o4) Nanomaterials, Jeffrey Edward Hernandez

Open Access Theses & Dissertations

Chromium is a very versatile metal that is used for many applications in the world. Two of the most common ions of chromium that occur naturally are Cr(III) and Cr(VI). These two oxidation states have very different heath effects in living organisms. Cr(III) is relatively non-toxic to living organisms; however, Cr(VI) is very toxic to most living organisms This study was conducted to find a simple and cost effective method to sequester these two common ionic species of chromium from sources of water that are adjacent to or that are affected by other water sources contaminated by these two ions. …

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Structural Investigation Of Atp-Utilizing Enzymes: Structures Involved In H+ Homeostasis And The Proliferation Of Hormone-Dependent Cancers, Zacariah Louis Hildenbrand Jan 2010

Structural Investigation Of Atp-Utilizing Enzymes: Structures Involved In H+ Homeostasis And The Proliferation Of Hormone-Dependent Cancers, Zacariah Louis Hildenbrand

Open Access Theses & Dissertations

ATP is a multifunctional nucleotide considered to be the "molecular unit of currency" of intracellular energy transfer. ATP is utilized ubiquitously for the transport of chemical energy within the cell in addition to acting as a substrate in the regulation of many metabolic and signaling transduction pathways such as kinase-mediated signaling cascades. Interestingly, the functional mechanisms of many enzymes require the binding of ATP to trigger key structural and conformational changes that ultimately result in enzyme-directed catalysis. Two of the most omnipresent ATPases within the cell include the V-ATPase rotary proton pump and the Hsp90 protein-folding chaperone. Structural and biochemical …

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The Use Of Protective Behavioral Strategies Is Related To Reduced Risk In Heavy Drinking College Students With Poorer Mental And Physical Health, Joseph W. Labrie, Shannon R. Kenney, Andrew Lac Jan 2010

The Use Of Protective Behavioral Strategies Is Related To Reduced Risk In Heavy Drinking College Students With Poorer Mental And Physical Health, Joseph W. Labrie, Shannon R. Kenney, Andrew Lac

Heads Up!

The present study examined the moderating role of health status (physical, mental, and social health) and the relationships between protective behavioral strategies utilized to reduce high-risk drinking (e.g., avoiding drinking games, setting consumption limits, or having a designated driver) and alcohol use and negative consequences in a sample of heavy drinking college students (N = 1,820). In this high risk sample, multiple regression analyses showed that stronger social health was related to increased drinking, while poorer physical, mental, and social health were related to increased alcohol negative consequences. Further, moderation effects revealed that increasing the use of protective behaviors …

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Contention Of Lust, Caution: Sexuality, Visuality And Female Subjectivity, Yanjie Wang Jan 2010

Contention Of Lust, Caution: Sexuality, Visuality And Female Subjectivity, Yanjie Wang

Asian and Asian American Studies Faculty Works

This paper investigates the ways in which Ang Lee provides new insights into subject formation in his film Lust, Caution (Se Jie, 2007). In the paradigm of structuralism, the subject is defined, as well as confined, by the symbolic order or the dominant ideology. The puzzle therefore rests on how to explain the subject’s negotiation with its normative identity, its denial thereof, or even its subversion of said identity. In a close reading of the female protagonist’s subject formation in Lust, Caution, this paper acknowledges the power of ideology, specifically the power of its interpellative operation, in constructing a subject. …

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Fatal Flirting: The Nazi State And The Seventh-Day Adventist Church, Harold Alomía Jan 2010

Fatal Flirting: The Nazi State And The Seventh-Day Adventist Church, Harold Alomía

Journal of Adventist Mission Studies

No abstract provided.

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Race, Ethnicity, And Tribal Conflicts, Joel Musvosvi Jan 2010

Race, Ethnicity, And Tribal Conflicts, Joel Musvosvi

Journal of Adventist Mission Studies

No abstract provided.

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Improving Efficiencies And Modeling A Cyclic Suspended Ion Exchange (Six(C)) Drinking Water Pre-Treatment Systems, Owen P. Friend-Gray Jan 2010

Improving Efficiencies And Modeling A Cyclic Suspended Ion Exchange (Six(C)) Drinking Water Pre-Treatment Systems, Owen P. Friend-Gray

Master's Theses and Capstones

This research focused on three primary components of the Suspended Ion eXchange (SIX(c)) process developed by PWN Water Supply Company North Holland. The first step focused on the resin regeneration procedure. It was shown that the current system could be improved and that reducing the complexity of the system simplified the process and increased the regeneration efficiency. The second step focused on the resin tank contactor hydraulics. It was determined that for the sequential completely mixed reactor design at PWN, high flows with low mixing speed of the overhead paddle mixers led to the most efficient hydraulic regime. The third …

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Isotopic Analysis Of Arctic Ground Squirrel Tissues And Potential Food Sources, Julee Shamhart Jan 2010

Isotopic Analysis Of Arctic Ground Squirrel Tissues And Potential Food Sources, Julee Shamhart

Master's Theses and Capstones

Given limited knowledge of the food sources of Arctic ground squirrels, an important arctic prey species, it is difficult to predict the implications of changes in food source availability that could result from climate change. I hypothesized that Arctic ground squirrels at two colonies, Atigun and Toolik, would have similar feeding habits and mushrooms would contribute to their diet The Arctic ground squirrels at Toolik had significantly higher del15N (3.7 per mill difference) and del13C values (1.3 per mill difference) than those at Atigun. Mixing models indicated that the signatures observed in the Atigun hair could result from a combination …

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Ribosome Recycling Step In Yeast Cytoplasmic Protein Synthesis Is Catalyzed By Eef3 And Atp, Sarah F. Mitchell Jan 2010

Ribosome Recycling Step In Yeast Cytoplasmic Protein Synthesis Is Catalyzed By Eef3 And Atp, Sarah F. Mitchell

Chemistry and Biochemistry Faculty Works

After each round of protein biosynthesis, the posttermination complex (PoTC) consisting of a ribosome, mRNA, and tRNA must be disassembled into its components for a newround of translation. Here, we show that a Saccharomyces cerevisiae model PoTC was disassembled by ATP and eukaryotic elongation factor 3 (eEF3). GTP or ITP functioned with less efficiency and adenosine 5γ′-(β,γ-imido)triphosphate did not function at all. The kcat of eEF3 was 1.12 min-1, which is comparable to that of the in vitro initiation step. The disassembly reaction was inhibited by aminoglycosides and cycloheximide. The subunits formed from the yeast model PoTC remained separated under …

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Delayed Differentiation In Embryonic Stem Cells And Mesodermal Progenitors In The Absence Of Ctbp2, Heather Tarleton Jan 2010

Delayed Differentiation In Embryonic Stem Cells And Mesodermal Progenitors In The Absence Of Ctbp2, Heather Tarleton

Health and Human Sciences Faculty Works

Mammalian embryonic stem cells (ESCs) are characterized by an ability to self-renew and give rise to each of the three germ layers. ESCs are a pluripotential source of numerous primitive progenitors and committed lineages and can make stoichiometric decisions leading to either asymmetric or symmetric cell division. Several genes have been identified as essential for maintenance of self-renewal, but few non-lineage specific genes have been identified as essential for differentiation. We selected the chromatin factor Ctbp2 from microarray data for its enriched expression in stem cells, in comparison to committed progenitors. RNA interference (RNAi) was used to knockdown gene expression …

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Review: Back To Darwin, Timothy Shanahan Jan 2010

Review: Back To Darwin, Timothy Shanahan

Philosophy Faculty Works

No abstract provided.

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A Clever Ruse, Timothy Shanahan Jan 2010

A Clever Ruse, Timothy Shanahan

Philosophy Faculty Works

No abstract provided.

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A Comparison Of Tooth Wear And Breakage In Rancho La Brea Sabertooth Cats And Dire Wolves Across Time, Wendy J. Binder Jan 2010

A Comparison Of Tooth Wear And Breakage In Rancho La Brea Sabertooth Cats And Dire Wolves Across Time, Wendy J. Binder

Biology Faculty Works

The carnivores preserved in the late Pleistocene Rancho La Brea tar seep deposits display a remarkably high incidence of teeth broken in life as compared with modern species. In a previous study examining tooth breakage, tooth wear and individual age of Canis dirus over different periods in time, we found that Pit 13 C. dirus (about 15,000 years before present [ybp]) exhibited heavier tooth wear and fractured their teeth about three times more often than those of the younger Pit 61/67 (about 12,000 ybp). No significant difference was found in the age structure of the population, suggesting this came from …

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Erratum: The Biopax Community Standard For Pathway Data Sharing, Kam D. Dahlquist Jan 2010

Erratum: The Biopax Community Standard For Pathway Data Sharing, Kam D. Dahlquist

Biology Faculty Works

No abstract provided.

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Antagonistic Activity Of Selected Marine-Derived Streptomyces Spp. Against Plesiomonas Shigelloides., Angelyn Melaya Kloni Jan 2010

Antagonistic Activity Of Selected Marine-Derived Streptomyces Spp. Against Plesiomonas Shigelloides., Angelyn Melaya Kloni

Student Works (2010-2019)

In this study, primary and secondary screenings were conducted to evaluate the antibacterial and anti-yeast potential of the eleven selected marine-derived Streptomyces spp., particularly against P. shigelloides. The strains were categorized into three colour groups for morphological grouping according to the colour of aerial mycelium; namely grey, yellow green, and white colour groups. Diffusible pigments were produced by eight of the strains tested. Strain(s) from grey and white with red diffusible pigments colour groups displayed strong antibacterial activity. The yeasts tested were resistant to the bioactive metabolite(s) produced by some of the Streptomyces spp. which had shown high activity against …

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Synthesis, Characterization And Biological Activity Of Copper (Ii) And Zinc (Ii) Complexes Of Thiosemicarbazones And Their N(4)-Substituted Derivatives Derived From 2,4-Dihydroxybenzaldehyde., Tan Kong Wai Jan 2010

Synthesis, Characterization And Biological Activity Of Copper (Ii) And Zinc (Ii) Complexes Of Thiosemicarbazones And Their N(4)-Substituted Derivatives Derived From 2,4-Dihydroxybenzaldehyde., Tan Kong Wai

Student Works (2010-2019)

Four thiosemicarbazones ligands (1-4) have been prepared with good yield by refluxing 2,4-dihydroxybenzaldehyde with thiosemicarbazide or N(4)-substituted thiosemicarbazide in ethanol or methanol. From these four ligands, 16 new ternary metal complexes (5-20) with the general formulation of M(B)L have been prepared from the reactions of metal acetates with 2,4-dihydroxybenzaldehyde N(4)-substituted thiosemicarbazone in the presence of N,N-heterocyclic base (M2+ = Zn2+ or Cu2+; B = 2,2'-bipyridine, (bpy); 1,10-phenanthroline, (phen); L2- = doubly deprotonated thiosemicarbazones = 2,4-dihydroxybenzaldehyde thiosemicarbazonato, (HT); 2,4-dihydroxybenzaldehyde 4-methylthiosemicarbazonato, (HM); 2,4-dihydroxybenzaldehyde 4-ethylthiosemicarbazonato, (HE) and 2,4-dihydroxybenzaldehyde 4-phenylthiosemicarbazonato, (HP)) These compounds have been characterized by elemental analyses, IR, UV-Vis, NMR and magnetic …

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Globalization And International Development: Critical Issues Of The 21st Century, Sisay Asefa Editor Jan 2010

Globalization And International Development: Critical Issues Of The 21st Century, Sisay Asefa Editor

Upjohn Press

These papers address globalization issues with a special emphasis on its impact on poverty. Advances in transportation and telecommunications with instantaneous information and communication flows requires new approaches given the wide differences in cultures, political systems, languages, and ethnicities. Extreme variation in the international distributions of wealth, income, and poverty remain as enormous social problems to be addressed. In general, the contributors recommend expanding the flows between countries to accelerate growth and reduce inequalities. These flows include international trade and capital, migration, remittances, and foreign aid. But in addition to these hard commodities and dollars, there are flows of ideas, …

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Using The Andersen Behavioral Model Of Health Services Use To Examine Adult Uninsured Patient Health Services Use At A Community Health Center, Jewel Shonette Goodman Jan 2010

Using The Andersen Behavioral Model Of Health Services Use To Examine Adult Uninsured Patient Health Services Use At A Community Health Center, Jewel Shonette Goodman

Health Services Research Dissertations

Prescription medications are essential to the treatment and management of chronic conditions (Smith et al., 2005). Lack of access can result in pain, worsening of the condition and increased risk of additional health problems. Health care expenditures in the United States were reportedly 1.7 trillion in 2003 (Smithetal.,2005) and exceeded" role="presentation" style="box-sizing: border-box; display: inline-table; line-height: 0; font-size: 16.66px; overflow-wrap: normal; word-spacing: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; margin: 0px; padding: 1px 0px; position: relative;">1.7trillionin2003(Smithetal.,2005)andexceeded1.7trillionin2003(Smithetal.,2005)andexceeded2.3 trillion in 2008 (Centers for Medicare and Medicaid Services, 2010). Prescription medication costs …

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Prenatal Beta-Endorphin As An Early Predictor Of Postpartum Depressive Symptoms In Euthymic Women, Ilona S. Yim, Laura M. Glynn, Christine Dunkel Schetter, Calvin J. Hobel, Aleksandra Chicz-Demet, Curt A. Sandman Jan 2010

Prenatal Beta-Endorphin As An Early Predictor Of Postpartum Depressive Symptoms In Euthymic Women, Ilona S. Yim, Laura M. Glynn, Christine Dunkel Schetter, Calvin J. Hobel, Aleksandra Chicz-Demet, Curt A. Sandman

Psychology Faculty Articles and Research

After delivery, many women experience symptoms of postpartum depression (PPD), and early identification of women at risk is therefore important. The opioid peptide [beta]-endorphin has been implicated in non-puerperal depression but its role in the development of PPD is unknown.

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Evaluation Of Ten Extra-Alveolar Temporary Anchorage Device Insertion Sites By Cone Beam Volumetric Computer Tomography: A Pilot Study, Yi-Jyun Chen, Chia-Tze Kao, Tsui-Hsien Huang Jan 2010

Evaluation Of Ten Extra-Alveolar Temporary Anchorage Device Insertion Sites By Cone Beam Volumetric Computer Tomography: A Pilot Study, Yi-Jyun Chen, Chia-Tze Kao, Tsui-Hsien Huang

Journal of Dental Sciences

Background/Purpose In order to increase the success rate of temporary anchorage devices (TADs), it is important not to cause root injury or soft-tissue inflammation. The aim of the present study was to evaluate hard- and soft-tissue thicknesses of TAD insertion sites and the perforation ratio with different lengths of TADs by cone beam volumetric computed tomography (CBCT). Materials and methods The hard- and soft-tissue thicknesses were evaluated on 10 patients (5 males and 5 females) by CBCT. The ages ranged 20-36 years. Ten regions of interest (ROIs) in extra-alveolar bone were selected and based on anchorage requirements. Soft-tissue depths were …

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Gender, Sexuality, And The Authoritarian Personality, Bill E. Peterson, Eileen L. Zurbriggen Jan 2010

Gender, Sexuality, And The Authoritarian Personality, Bill E. Peterson, Eileen L. Zurbriggen

Psychology: Faculty Publications

The political correlates of the authoritarian personality have been well established by researchers, but important linkages to other major constructs in psychology need fuller elaboration. We present new data and review old data from our laboratories that show the myriad ways in which authoritarianism is implicated in the important domain of gender roles. We show that women and men high in authoritarianism live in rigidly gendered worlds where male and female roles are narrowly defined, attractiveness is based on traditional conceptions of masculinity and femininity, and conventional sexual mores are prescribed. As a construct, authoritarianism is not just relevant for …

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Bound Guidance: Fda Rulemaking For Off-Label Pharmaceutical Drug Marketing, Michael Jon Andersen Jan 2010

Bound Guidance: Fda Rulemaking For Off-Label Pharmaceutical Drug Marketing, Michael Jon Andersen

Case Western Reserve Law Review

No abstract provided.

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Graveside Birthday Parties: The Legal Consequences Of Forming Families Posthumously, Browne Lewis Jan 2010

Graveside Birthday Parties: The Legal Consequences Of Forming Families Posthumously, Browne Lewis

Case Western Reserve Law Review

No abstract provided.

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Advocates, Agendas, And Nay-Sayers: Science And Technology In The Public Arena, Arthur Greenberg Jan 2010

Advocates, Agendas, And Nay-Sayers: Science And Technology In The Public Arena, Arthur Greenberg

The University Dialogue

No abstract provided.

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Prove It! Let The Data Tell The Story, Institute For Health Policy And Practice (Ihpp), New Hampshire Department Of Health And Human Services Jan 2010

Prove It! Let The Data Tell The Story, Institute For Health Policy And Practice (Ihpp), New Hampshire Department Of Health And Human Services

All Materials

Prove It! Let the Data Tell the Story is a hands-on course focusing on the use of data and basic statistics commonly used in public health. NH community leaders expressed the need for training about using data to support their efforts to improve the health of their communities and Prove It! was conceptualized by the Empowering Communities project to meet that need. Prove It! provides a basic understanding of why we use data and how to use data in community health assessment and monitoring, using the specific focus on writing grant applications as the example.

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Visual Learning And Discrimination Of Abstract Visual Shapes By Crayfish, Matthew J. Boeve, Daniel A. Bergman Jan 2010

Visual Learning And Discrimination Of Abstract Visual Shapes By Crayfish, Matthew J. Boeve, Daniel A. Bergman

Student Summer Scholars Manuscripts

In nature, animals commonly experience multiple combinations of stimuli at various points in time. When two or more seemingly unrelated stimuli are detected at the same time using different sensory systems, there is the potential for an association to form between the stimuli. The animal may learn and show a response originally associated with one stimulus when it now detects the second stimulus. These stimuli are the unconditioned and conditioned stimulus of classical and operant conditioning. Many species of animals are known to learn via operant conditioning and a variety of responses can become associated with formerly neutral stimuli. Crayfish …

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Synthesis Of Cdte And Pbs Semiconductor Quantum Dots And Their Biological And Photochemical Applications, Xing Zhang Jan 2010

Synthesis Of Cdte And Pbs Semiconductor Quantum Dots And Their Biological And Photochemical Applications, Xing Zhang

Physics Theses - Archive

Semiconductor quantum dots are inorganic nanoparticles with unique photophysical properties. In particular, water soluble quantum dots which have been synthesized by colloidal chemistry in aqueous environment are highly luminescent. Their huge absorption cross sections, tunable, narrow emission bands and effectiveness of surface functionality have stimulated these luminescent probes in various applications like biological sensors as well as imaging contrast agents. In this paper we will discuss several aspects about the synthesize processes of the water soluble, highly luminescent type of CdTe quantum dots and its near infrared counterpart HgxCd1-xTe, the extremely crystallized PbS quantum dots with the application of the …

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Global Behavior Of Difference Equations, Ann M. Brett Jan 2010

Global Behavior Of Difference Equations, Ann M. Brett

Open Access Dissertations

In my first manuscript, I investigate the global stability character of the equilibrium points and the period-two solutions of [special characters omitted] with positive parameters and nonnegative initial conditions. I show that every solution of the equation in the title converges to either the zero equilibrium, the positive equilibrium or the period-two solution, for all values of parameters outside of a specific set defined in the paper. In the case when the equilibrium points and period-two solution coexist I give a precise description of the basins of attraction of all points. My results give an affirmative answer to Conjecture 9.5.6 …

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Antagonism Of Bacterial Cell To Cell Signalling By Metabolites Of Marine Gram-Positive Bacteria, Margaret E. Teasdale Jan 2010

Antagonism Of Bacterial Cell To Cell Signalling By Metabolites Of Marine Gram-Positive Bacteria, Margaret E. Teasdale

Open Access Dissertations

A form of communication in bacteria called quorum sensing (QS) regulates both microbial biofilm development and pathogenesis. QS is a process by which bacteria take a census of their numbers and regulate specific phenotypic expression using small signaling molecules called autoinducers. Interference with QS has been identified as a potentially novel therapeutic approach to the treatment of bacterial infections. This attenuation of the bacterial community prevents the successful establishment of an infection. The second chapter discusses the isolation of causative agents of bioluminescence inhibition in Vibrio harveyi. Bioassay-guided fractionation lead to the isolation of two arylethylamides from isolate C42, a …

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Lead Exposure, Aging And Biomarkers In Alzheimer's Disease, Aderemi Dosunmu Jan 2010

Lead Exposure, Aging And Biomarkers In Alzheimer's Disease, Aderemi Dosunmu

Open Access Dissertations

Alzheimer's disease (AD) is a progressive neurodegenerative disease. To investigate AD risk factors, we reviewed epidemiologic case control studies and recent research for AD's connection to the environment. Next, we examined the number one risk factor in AD, aging. We compared and contrasted lifespan profiles of AD-associated mRNA and protein levels in monkeys and mice. The AD-related biomarkers were APP mRNA and protein; Aβ levels; specificity protein 1 (SP1); and the β-amyloid precursor cleaving enzyme (BACE1). In mice, APP and Sp1 mRNA and their protein products were elevated late in life; Aβ levels declined. In monkeys, APP, Sp1, and BACE1 …

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