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Wing Pathology Of White-Nose Syndrome In Bats Suggests Life-Threatening Disruption Of Physiology, Paul M. Cryan, Carol Uphoff Meteyer, Justin G. Boyles

KIP Articles

White-nose syndrome (WNS) is causing unprecedented declines in several species of North American bats. The characteristic lesions of WNS are caused by the fungus Geomyces destructans, which erodes and replaces the living skin of bats while they hibernate. It is unknown how this infection kills the bats. We review here the unique physiological importance of wings to hibernating bats in relation to the damage caused by G. destructans and propose that mortality is caused by catastrophic disruption of wing-dependent physiological functions. Mechanisms of disease associated with G. destructans seem specific to hibernating bats and are most analogous to disease caused …

Exponent, Vol. 42, Iss. 10, 2010-11-11, University Of Alabama In Huntsville

2010

No abstract provided.

Central Florida Future, Vol. 42 No. 71, November 11, 2010

Central Florida Future

Cheating uproar hits UCF; Bidding starts at; Gambling plagues college students; SGA pushes for parking at IM fields.

The Alestle - Vol. 63 No. 12 - 11/11/2010, Southern Illinois University Edwardsville

The Alestle

Vol. 63 No. 12

Kenyon Collegian - November 11, 2010

The Kenyon Collegian

No abstract provided.

Leishmania Major Survival In Selective Phlebotomus Papatasi Sand Fly Vector Requires A Specific Scg-Encoded Lipophosphoglycan Galactosylation Pattern, Deborah E. Dobson, Shaden Kamhawi, Phillip Lawyer, Salvatore J. Turco, Stephen M. Beverley, David L. Sacks

Molecular and Cellular Biochemistry Faculty Publications

Phlebotomine sand flies that transmit the protozoan parasite Leishmania differ greatly in their ability to support different parasite species or strains in the laboratory: while some show considerable selectivity, others are more permissive. In "selective" sand flies, Leishmania binding and survival in the fly midgut typically depends upon the abundant promastigote surface adhesin lipophosphoglycan (LPG), which exhibits species- and strain-specific modifications of the dominant phosphoglycan (PG) repeat units. For the "selective" fly Phlebotomus papatasi PpapJ, side chain galactosyl-modifications (scGal) of PG repeats play key roles in parasite binding. We probed the specificity and properties of this scGal-LPG PAMP (Pathogen Associated …

T-Lymphocyte Responses To Intestinally Absorbed Antigens Can Contribute To Adipose Tissue Inflammation And Glucose Intolerance During High Fat Feeding, Yuehui Wang, Jianing Li, Lihua Tang, Yu Wang, Richard Charnigo, Willem De Villiers, Erik Eckhardt

Internal Medicine Faculty Publications

BACKGROUND: Obesity is associated with inflammation of visceral adipose tissues, which increases the risk for insulin resistance. Animal models suggest that T-lymphocyte infiltration is an important early step, although it is unclear why these cells are attracted. We have recently demonstrated that dietary triglycerides, major components of high fat diets, promote intestinal absorption of a protein antigen (ovalbumin, "OVA"). The antigen was partly transported on chylomicrons, which are prominently cleared in adipose tissues. We hypothesized that intestinally absorbed gut antigens may cause T-lymphocyte associated inflammation in adipose tissue.

METHODOLOGY/PRINCIPAL FINDINGS: Triglyceride absorption promoted intestinal absorption of OVA into adipose tissue, …

The George-Anne, Georgia Southern University

The George-Anne

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Interactive Stem Cells: Education Through Game Design, Sarah Hudson

Theses

In my thesis I developed an interactive website intended to educate the non-scientific or lay public about stem cells. Most people have heard about stem cells but few truly understand them. It would be beneficial to those wishing to engage in the current stem cell debate to be more thoroughly educated. Currently, the information available is all geared towards scientists or from a biased source. I used a series of Flash games to convey the important information in an engaging way. The site is intuitive enough that even users unfamiliar with the Internet and basic high-school science knowledge will be …

Importance Of Phase Unwrapping For The Reconstruction Of Microwave Tomographic Images, Tomasz M. Grzegorczyk, Paul M. Meaney, Soon Ik Jeon, Shireen D. Geimer, Keith D. Paulsen

Dartmouth Scholarship

Microwave image reconstruction is typically based on a regularized least-square minimization of either the complex-valued field difference between recorded and modeled data or the logarithmic transformation of these field differences. Prior work has shown anecdotally that the latter outperforms the former in limited surveys of simulated and experimental phantom results. In this paper, we provide a theoretical explanation of these empirical findings by developing closed form solutions for the fie

Lanthorn, Vol. 45, No. 23, November 11, 2010, Grand Valley State University

Volume 45, July 8, 2010 - June 9, 2011

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

The Cord (November 10, 2010)

The Cord

No abstract provided.

Spartan Daily November 10, 2010, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 135, Issue 40

November 10, 2010 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Resonance Assignments And Secondary Structure Predictions Of The As(Iii) Metallochaperone Arsd In Solution, Jun Ye, Yanan He, Jack Skalicky, Barry P. Rosen, Timothy L. Stemmler

Biochemistry and Molecular Biology Faculty Publications

ArsD is a metallochaperone that delivers As(III) to the ArsA ATPase, the catalytic subunit of the ArsAB pump encoded by the arsRDABC operon of Escherichia coli plasmid R773. Conserved ArsD cysteine residues (Cys12, Cys13 and Cys18) construct the As(III) binding site of the protein, however a global structural understanding of this arsenic binding remains unclear. We have obtained NMR assignments for ArsD as a starting point for probing structural changes on the protein that occur in response to metalloid binding and upon formation of a complex with ArsA. The predicted solution structure of ArsD is in agreement with recently published …

Investigating The Spectrum Of Biological Activity Of Ring-Substituted Salicylanilides And Carbamoylphenylcarbamates, Jiahui Guo, Aidan Coffey, Et. Al.

Department of Biological Sciences Publications

In this study, a series of twelve ring-substituted salicylanilides and carbamoylphenylcarbamates were prepared and characterized. The compounds were analyzed using RP-HPLC to determine lipophilicity. They were tested for their activity related to the inhibition of photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts. Moreover, their site of action in the photosynthetic apparatus was determined. Primary in vitro screening of the synthesized compounds was also performed against mycobacterial, bacterial and fungal strains. Several compounds showed biological activity comparable with or higher than the standards 3-(3,4-dichlorophenyl)-1,1-dimethylurea, isoniazid, penicillin G, ciprofloxacin or fluconazole. The most active compounds showed minimal anti-proliferative activity …

The Winonan, Winona State University

The Winonan - 2010s

No abstract provided.

The Utah Statesman, November 10, 2010, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Daily Gamecock, Wednesday, November 10, 2010, University Of South Carolina - Aiken

November

No abstract provided.

2010 Gala Program, New York Law School

Gala Programs

Honoring
Diane Abbey, Founder, Diane Abbey Law Center for Children and Families
Bruce A. Colbath ’85, Partner, Weil, Gotshal & Manges LLP
Steven M. Klosk ’87, President and CEO, Cambrex Corporation

Woods Couchman Appointed Professor Emerita, Alicia Rohan

Browse All News

No abstract provided.

Shalev Appointed To The Nancy R. And Eugene C. Gwaltney Family Endowed Chair In Juvenile Diabetes Research, Jim Bakken

Browse All News

No abstract provided.

Interaction-Dependent Pcr: Identification Of Ligand-Target Pairs From Libraries Of Ligands And Libraries Of Targets In A Single Solution-Phase Experiment, Lynn M. Mcgregor, David J. Gorin, Christoph E. Dumelin, David R. Liu

Chemistry: Faculty Publications

Interaction-dependent PCR (IDPCR) is a solution-phase method to identify binding partners from combined libraries of small-molecule ligands and targets in a single experiment. Binding between DNA-linked targets and DNA-linked ligands induces formation of an extendable duplex. Extension links codes that identify the ligand and target into one selectively amplifiable DNA molecule. In a model selection, IDPCR resulted in the enrichment of DNA encoding all five known protein-ligand pairs out of 67 599 possible sequences.

Spectator 2010-11-10, Editors Of The Spectator

The Spectator

No abstract provided.

Volume 48, Number 12: November 10, 2010, University Of North Dakota

University Letter Archive

No abstract provided.

The Lumberjack, November 10, 2010

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Robert Knight, Robert Knight, Margaret Devore

Voices from the Stream: An Environmental History of the St. Johns River

Robert Knight, leading expert and scientist working on protection of Florida springs and executive director of the Florida Springs Institute, interviewed by Margaret Devore on November 10, 2010.

Evaluation Of Deep Geologic Units In Florida For Potential Use In Carbon Dioxide Sequestration, Tina Roberts-Ashby

USF Tampa Graduate Theses and Dissertations

Concerns about elevated atmospheric carbon dioxide (CO

2

) and the effect on

global climate have created proposals for the reduction of carbon emissions from large

stationary sources, such as power plants. Carbon dioxide capture and sequestration

(CCS) in deep geologic units is being considered by Florida electric-utilities. Carbon

dioxide-enhanced oil recovery (CO

2

-EOR) is a form of CCS that could offset some of the

costs associated with geologic sequestration. Two potential reservoirs for geologic

sequestration were evaluated in south-central and southern Florida: the Paleocene

Cedar Keys Formation/Upper Cretaceous Lawson Formation (CKLIZ) and the Lower

Cretaceous Sunniland Formation along …

Novel Roles For 185delag Mutant Brca1 In Ovarian Cancer Pathology, Rebecca J. Linger

USF Tampa Graduate Theses and Dissertations

Familial history is the strongest risk factor for developing ovarian cancer (OC), and a significant contributor to breast cancer risk. Most hereditary breast cancers and OCs are associated with mutation of the tumor suppressor Breast and Ovarian Cancer Susceptibility Gene 1 (BRCA1). Studying risk-associated BRCA1 truncation mutations, such as the founder mutation 185delAG, may reveal signaling pathways important in OC etiology. Recent studies have shown novel BRCA1 mutant functions that may contribute to breast and OC initiation and progression independent of the loss of wtBRCA1. Previously, we have found that normal human ovarian surface epithelial (HOSE) cells expressing the 185delAG …

Libs And Lite Emission Based Laser Remote Sensing Of Chemical Species And Enhanced Modeling Of Atmospheric Absorption, Dzianis V. Pliutau

USF Tampa Graduate Theses and Dissertations

Laser-Induced Breakdown spectroscopy (LIBS) and Laser-Induced Thermal Emission (LITE) emission based laser remote sensing were investigated with the application to the remote measurements of trace chemical species. In particular, UVvisible LIBS and Mid-IR LITE systems were developed and measurements of remote targets and chemical surfaces were studied. The propagation through the atmosphere of the multi-wavelength backscattered LIBS and LITE optical spectrum with atmospheric absorption effects on the returned lidar signal was investigated. An enhanced model of the atmospheric effects on emission-based laser-remote sensing was developed and found to be consistent and in agreement with our experimental results.

LITE measurements were …