Digital Commons Network^™

Parental Depression And Offspring Psychopathology: A Children Of Twins Study, A. L. Singh, B. M. D'Onofrio, W. S. Slutske, E. Turkheimer, R. E. Emery, K. P. Harden, A. C. Heath, P. A F Madden, D. J. Statham, N. G. Martin

Open Access Publications

No abstract provided.

Resource Pack On Active Learning, Roisin Donnelly, Marian Fitzmaurice

Other resources

Introduction - The massification of higher education is now a global phenomenon - Huge changes in the teaching and learning milieu within colleges - The forces of massification have brought multiple challenges with regard to pedagogy - What kind of pedagogy to employ? - The role of the lecturer is to empower learning and it is challenging and complex - There is a need to employ a pedagogy which requires students to do things, to access information, to solve problems, to reflect on what they are doing and make connections to real world problems.

Educational research has revealed a number …

The $1,000 Genome, The $100,000 Analysis?, Elaine R. Mardis

Open Access Publications

No abstract provided.

Molecular Remodeling Of Ion Channels, Exchangers And Pumps In Atrial And Ventricular Myocytes In Ischemic Cardiomyopathy, Naomi Gronich, Azad Kumar, Yuwei Zhang, Igor R. Efimov, Nikolai M. Soldatov

Open Access Publications

No abstract provided.

Vesicular Neurotransmitter Transporter Trafficking In Vivo: Moving From Cells To Flies, Anna Grygoruk, Hao Fei, Richard W. Daniels, Bradley R. Miller, Audrey Chen, Aaron Diantonio, David E. Krantz

Open Access Publications

No abstract provided.

The Spindle Position Checkpoint Is Coordinated By The Elm1 Kinase, Jeffrey K. Moore, Prakash Chudalayandi, Richard A. Heil-Chapdelaine, John A. Cooper

Open Access Publications

How dividing cells monitor the effective transmission of genomes during mitosis is poorly understood. Budding yeast use a signaling pathway known as the spindle position checkpoint (SPC) to ensure the arrival of one end of the mitotic spindle in the nascent daughter cell. An important question is how SPC activity is coordinated with mother-daughter polarity. We sought to identify factors at the bud neck, the junction between mother and bud, which contribute to checkpoint signaling. In this paper, we show that the protein kinase Elm1 is an obligate regulator of the SPC, and this function requires localization of Elm1 to …

Short-Term Signatures Of Evolutionary Change In The Salmonella Enterica Serovar Typhimurium 14028 Genome, Tyler Jarvik, Chris Smillie, Eduardo A. Groisman, Howard Ochman

Open Access Publications

No abstract provided.

Expression Of The Baba Adhesin During Experimental Infection With Helicobacter Pylori, Cathy M. Styer, Lori M. Hansen, Cara L. Cooke, Amy M. Gundersen, Sung Sook Choi, Douglas E. Berg, Mohammed Benghezal, Barry J. Marshall, Richard M. Peek Jr, Thomas Boren, Jay V. Solnick

Open Access Publications

No abstract provided.

Roles Of Membrane Trafficking In Nerve Repair And Regeneration, Elizabeth Tuck, Valeria Cavalli

Open Access Publications

No abstract provided.

Organogenetic Tolerance, Marc R. Hammerman

Open Access Publications

No abstract provided.

A Legacy Of Strife: Rebellious Slaves In Sixteenth-Century Panamá, Ignacio Gallup-Diaz

History Faculty Research and Scholarship

No abstract provided.

En Torno Al Género Negro: ¿La Disolución De Una Conciencia Ética O La Recuperación De Un Nuevo Compromiso Político?, Rosi Song

Spanish Faculty Research and Scholarship

No abstract provided.

Reputation In A Networked World: Revisiting The Social Foundations Of Defamation Law, David S. Ardia

Faculty Publications

No abstract provided.

Enabling Responsible Public Genomics, John M. Conley, Adam K. Doerr, Daniel B. Vorhaus

Faculty Publications

No abstract provided.

Applying Geographic Information Systems To Support Strategic Environmental Assessment: Opportunities And Limitations In The Context Of Irish Land-Use Plans, Ainhoa Gonzalez, Alan Gilmer, Ronan Foley, John Sweeney, John Fry

Articles

The strengthening of spatial database infrastructures, further promoted by the INSPIRE Directive adopted in 2007, has led to an increased use of spatial data in planning and decision-making. Given that land-use plans are intrinsically spatial, such evidence and approaches can significantly benefit plan-making. A spatial framework could especially support the specific Strategic Environmental Assessment (SEA) aspects of the plan-making process. Spatial tools such as Geographic Information Systems (GIS) are particularly well-placed to support the environmental integration sought in SEA by providing evidence through the spatial assessment of multiple environmental datasets. Moreover, GIS bring the opportunity to augment conventional assessment techniques …

Prominence Driven Character Animation, Charlie Cullen, Paula Mcgloin, Anna Deegan, Evin Mccarthy

Conference papers

This paper details the development of a fully automated system for character animation implemented in Autodesk Maya. The system uses prioritised speech events to algorithmically generate head, body, arms and leg movements alongside eyeblinks, eyebrow movements and lip-synching. In addition, gaze tracking is also generated automatically relative to the definition of focus objects- contextually important objects in the character's worldview. The plugin uses an animation profile to store the relevant controllers and movements for a specific character, allowing any character to run with the system. Once a profile has been created, an audio file can be loaded and animated with …

The Role Of Sustainability In Scm: The Case Of The Sustainable Packaging Supply Chain, Edward Sweeney

Practitioner Journals

No abstract provided.

Macular Pigment And Its Contribution To Visual Performance And Experience, James Loughman, Peter Davison, John Nolan, Mukunda Akkali, Stephen Beatty

Articles

There is now a consensus, based on histological, biochemical and spectral absorption data, that the yellow colour observed at the macula lutea is a consequence of the selective accumulation of dietary xanthophylls in the central retina of the living eye. Scientifi c research continues to explore the function(s) of MP in the human retina, with two main hypotheses premised on its putative capacity to (1) protect the retina from (photo)-oxidative damage by means of its optical fi ltration and/or antioxidant properties, the so-called protective hypothesis and (2) infl uence the quality of visual performance by means of selective short wavelength …

Evaluation Of The Potential Of Raman Microspectroscopy For Prediction Of Chemotherapeutic Response To Cisplatin In Lung Adenocarcinoma, Haq Nawaz, Franck Bonnier, Peter Knief, Orla Howe, Fiona Lyng, Aidan Meade, Hugh Byrne

Articles

The study of the interaction of anticancer drugs with mammalian cells in vitro is important to elucidate the mechanisms of action of the drug on its biological targets. In this context, Raman spectroscopy is a potential candidate for high throughput, noninvasive analysis. To explore this potential, the interaction of cis-Diamminedichloroplatinum (II) (Cisplatin) with a human lung adenocarcinoma cell line (A549) was investigated using Raman microspectroscopy. The results were correlated with parallel measurements from the MTT cytotoxicity assay, which yielded an IC50 value of 1.2±0.2 μM. To further confirm the spectral results, Raman spectra were also acquired from DNA extracted from …

Solar Simulated Radiation Induced Cell Death Depends On Spectral Distribution And Irradiance But Not Output Delivery, Alanna Maguire, Fiona Lyng, James Walsh

Articles

Photo biological investigations are dependent on calibration and characterisation to determine the relevance of an artificial irradiator to the study at hand. The importance of this has been voiced in the literature. However, the importance of output delivery is relatively unknown. The biological relevance of a high energy, rapidly pulsing solar simulator was investigated using the clonogenic assay and was found to be reciprocity law compliant despite an exaggerated UV irradiance in excess of 1600 Wm-2 delivered per pulse. In fact, it was found to be the least cytotoxic irradiator compared to a second solar simulator and a UVB fluorescent …

Investigation Of The Influence Of High Risk Human Papillomavirus On The Biochemical Composition Of Cervical Cancer Cells Using Vibrational Spectroscopy, Kamila Ostrowska, Alison Malkin, Aidan Meade, John O'Leary, Cara Martin, Cathy Spillane, Hugh Byrne, Fiona Lyng

Articles

The main aetiology of cervical cancer is infection with high risk human papillomavirus (HPV). Cervical cancer is almost 100% curable if detected in the early stages. Thus, information about the presence and levels of HPV in patient samples has high clinical value. As current screening methods, such as the Pap smear test, are highly subjective and in many cases show low sensitivity and specificity, new supportive techniques are desirable to improve the quality of cervical cancer screening. In this study, vibrational spectroscopic techniques (Raman and Fourier Transform Infra Red absorption) have been applied to the investigation of four cervical cancer …

Speech Intelligibility From Image Processing, Andrew Hines, Naomi Harte

Articles

Hearing loss research has traditionally been based on perceptual criteria, speech intelligibility and threshold levels. The development of computational models of the auditory-periphery has allowed experimentation via simulation to provide quantitative, repeatable results at a more granular level than would be practical with clinical research on human subjects.

Theorizing And Litigating The Rights Of Sexual Minorities, Nancy Levit

Faculty Works

One of the best measures of a society is how it treats its vulnerable groups. A central idea in Professor Martha Nussbaum's writings is that all humans "are of equal dignity and worth, no matter where they are situated in society." The strategic challenge in lesbian, gay, bisexual and transgendered (LGBT) rights litigation is how to get courts to see sexual minorities as people worthy of equal dignity and respect. This article focuses on the roles of a positive emotion - love - and a procedural method of proof - science - in the shaping of laws defining the rights …

Evaluation Of Fish And Macroinvertebrate Indices Of Biotic Integrity In The Bioassessment Of The Illinois River Basin, Rebekah Hotz

Inquiry: The University of Arkansas Undergraduate Research Journal

Evaluating performances of the fish and invertebrate Indices of Biotic Integrity (IBIs) for a region is important to maintain rigorous assessment of the environmental quality of streams, especially with increasing urbanization. Timing of the assessment is considered important, with the critical season (low flow, high temperature) preferred, but the primary season (spring– summer) may be as efficient. I assisted with the collection and analysis of fish and macroinvertebrates using methods developed by the United States Environmental Protection Agency’s (USEPA) Rapid Bioassessment Protocols (RBPs) and the Arkansas Department of Environmental Quality (ADEQ), along with obtaining habitat and chemical assessments during primary …

Bioethics And Biosecurity Education In China: Rise Of A Scientific Superpower., Barr S. Michael, Joy Yueyue Zhang

Book Chapters

This chapter explores ethics, education and the life sciences in China. It is based on work conducted by the authors in two separate but complimentary projects. Barr’s observations derive from interviews and discussions in Beijing, Shanghai and Guangzhou with life scientists and policymakers in infectious-disease hospitals, university-research labs, the Chinese Academy of Sciences, and the Ministry of Health. Zhang’s study focused on China’s governance of stem-cell research and involved interviews with scientists, ethicists and policymakers at more than 25 sites across China. Below, we set the context by describing the role of science in China’s quest to become a leading …

Establishing Legal Permanence For The Child, Donald N. Duquette

Book Chapters

This chapter is intended to identify options for legal permanency that state law and the federal Adoption and Safe Families Act of 1997 (ASFA) commonly recognize to better serve children in foster care. Ideally, the child will ultimately return safely to his or her home of origin. But when a return home is not possible, the child welfare legal process should result in a safe and legally secure alternative permanent placement for the child. The emphasis on legally secure permanent placement is meant to provide the child with psychological stability and a sense of belonging and to limit the likelihood …

Wrongful Convictions: Adversarial And Inquisitorial Themes, Kent Roach

North Carolina Journal of International Law

No abstract provided.

Can There Be A Progressive Bioethics?, Richard O. Lempert

Book Chapters

Progressive bioethics-the words are not an oxymoron. Far from it; they are more redundant than oppositional. Yet they leave me almost as uneasy, as if they were contradictory. My unease exists because bioethics should be neither progressive nor regressive, neither right wing nor left wing, neither liberal nor conservative. It should be just good, sound ethics applied to the often difficult moral problems posed by present-day medicine and the genomic revolution.

I do not mean to suggest by this that all bioethicists need agree. Respectable ethicists using established modes of ethical analysis have long disagreed on and argued for different …

Measurements Of Platinum Electrode Potential In Blood And Blood Plasma And Serum, Mogely Khubutiya, Anatoly K. Evseev, Vladimir Kolesnikov, Mikhail M. Goldin, Alexei Davydov, Alexander Volkov, Andrey Stepanov

Faculty Publications and Presentations

The method of electrochemical pretreatment of platinum electrode with the goal of standardizing the initial state of electrode surface and its open-circuit potential (OCP) in the blood and other biological media is proposed. The platinum electrode potential is measured in 0.14 M Na2SO4 aqueous solution, in the blood and blood plasma and serum. By the examples of OCP measured in the blood serum of patients with acute poisoning, acute cerebral pathology and patients treated by the method of hyperbaric oxygenation, it was found that the values of blood serum OCP were different for studied pathological states and healthy people.

Garden Of The Gods At Colorado Springs: Paleozoic And Mesozoic Sedimentation And Tectonics, Marcus R. Ross, William A. Hoesch, Steven A. Austin, John H. Whitmore, Timothy L. Clarey

Faculty Publications and Presentations

Exposed along the southeast fl ank of the Colorado Front Range are rocks that beautifully illustrate the interplay of sedimentation and tectonics. Two major rangebounding faults, the Ute Pass fault and the Rampart Range fault, converge on the Garden of the Gods region west of Colorado Springs. Cambrian through Cretaceous strata upturned by these faults reveal in their grain compositions, textures, and bedforms radically different styles of sedimentation. The Cambrian/Ordovician marine transgressive deposits appear to have come to rest on a passive and tectonically inactive craton. In contrast, coarse-grained Pennsylvanian/Permian marine deposits of the Fountain Formation and Lyons Sandstone reveal …