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2010

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"Clad In Their Country Gray": Eighteenth-Century Fashion In Monmouth County, New Jersey, Morgan E. Glossbrenner Dec 2010

"Clad In Their Country Gray": Eighteenth-Century Fashion In Monmouth County, New Jersey, Morgan E. Glossbrenner

Pell Scholars and Senior Theses

A collection assessment to determine how well the Monmouth County Historical Association's eighteenth-century fashion fits into the organization's mission.


Progressivism And The Executive Branch: Woodrow Wilson's Expansion Of Presidential Power, Christopher F. Fisher Dec 2010

Progressivism And The Executive Branch: Woodrow Wilson's Expansion Of Presidential Power, Christopher F. Fisher

Pell Scholars and Senior Theses

This paper examines how and to what degree Woodrow Wilson expanded the power of the president. After the Civil War, immigration, urbanization, and industrialization changed America. Progressives like Wilson argued that many of these changes were harmful to society. Wilson argued that a president with an expanded role, supplemented by administrative bureaucracies, could solve what Progressives believed were the problems of capitalism and the Founder's vision of America.


Physical Activity: The Future Of Learning?, Michael W. Beets, Amanda E. Paluch, Edward C. Archer, Steven N. Blair Dec 2010

Physical Activity: The Future Of Learning?, Michael W. Beets, Amanda E. Paluch, Edward C. Archer, Steven N. Blair

Faculty Publications

No abstract provided.


The Inquiry Learning Model As An Approach To Mathematics Instruction, Michael C. Brune Dec 2010

The Inquiry Learning Model As An Approach To Mathematics Instruction, Michael C. Brune

Boise State University Theses and Dissertations

Since current approaches to mathematical instruction fall short of the goals of NCTM (National Council of Teachers of Mathematics) research was conducted in a small rural school district in the northwest United States evaluating inquiry based instruction. To complete the study two high school geometry classes were taught area formulation using a traditional lecture based approach to instruction. A third geometry class was taught area formulation utilizing inquiry-based instructional methods. Students in both groups took both a pre-test and post-test, filled out a questionnaire, and participated in a project designed to test their applications of mathematical understanding. Results indicated that …


A Man Older Than His Years: Franklin D. Roosevelt's Last Days, Bryan Vieira Dec 2010

A Man Older Than His Years: Franklin D. Roosevelt's Last Days, Bryan Vieira

Pell Scholars and Senior Theses

In April 1945, all seemed well in the United States; the end of the war in Europe was within the grasps of the Allied forces as they drove their invasion into the heart of the European Theatre. On April 12 of that year, however, the thirty-second President of the United States, Franklin Delano Roosevelt, died in Warm Springs, Georgia. The news concerning President Roosevelt sent shock waves around the world. The cause of the death of Roosevelt was in question, because no autopsy was performed; the surgeon general of the U.S. Navy and Roosevelt's personal physician, Vice Admiral Ross T. …


France As A Negative Influence On The Côte D’Ivoire: The Consequences Of Foreign Interference, Courtney P. Conroy Dec 2010

France As A Negative Influence On The Côte D’Ivoire: The Consequences Of Foreign Interference, Courtney P. Conroy

Pell Scholars and Senior Theses

The Côte d’Ivoire, like many African nations, has been greatly influenced by the presence of foreign powers. However, the case of the Côte d’Ivoire is unique because of the country’s contemporary and continuous relations with France – despite the many negative consequences that this relationship has produced. By examining the presence of the European colonial power throughout the history of the Côte d’Ivoire, it is clear that a direct link between the French and the modern problems of the Côte d’Ivoire, specifically when addressing unfair and authoritative rulers, weighted social stratifications, issues with economy, trade, and the Ivoirian Civil War …


Norman Morrison Isham: Newport Restoration Foreshadows Modern Preservation, Alyssa Lozupone Dec 2010

Norman Morrison Isham: Newport Restoration Foreshadows Modern Preservation, Alyssa Lozupone

Pell Scholars and Senior Theses

Norman Morrison Isham was an authority on Newport’s Colonial architecture and was hired to guide local restoration projects in Newport, Rhode Island. These projects, ranging in date from 1914 to 1931, included the Redwood Library, the Wanton-Lyman-Hazard House, The Colony House, and the Brick Market. Isham’s work is representative of an early period of preservation, and as such, Isham worked prior modern day historic preservation standards and guidelines. An analysis of Isham’s restoration work in Newport provides insight into the elements that compose his preservation theory and how his theory, as carried out with Colonial era structures in Newport, foreshadows …


Analysis Of Nitrogen Loading Reductions For Wastewater Treatment Facilities And Non-Point Sources In The Great Bay Estuary Watershed, Philip Trowbridge, Thomas S. Burack, Michael J. Walls, Harry T. Stewart Dec 2010

Analysis Of Nitrogen Loading Reductions For Wastewater Treatment Facilities And Non-Point Sources In The Great Bay Estuary Watershed, Philip Trowbridge, Thomas S. Burack, Michael J. Walls, Harry T. Stewart

PREP Reports & Publications

In 2009, the New Hampshire Department of Environmental Services (DES) published a proposal for numeric nutrient criteria for the Great Bay Estuary. The report found that total nitrogen concentrations in most of the estuary needed to be less than 0.3 mg N/L to prevent loss of eelgrass habitat and less than 0.45 mg N/L to prevent occurrences of low dissolved oxygen. Based on these criteria and an analysis of a compilation of data from at least seven different sources, DES concluded that 11 of the 18 subestuaries in the Great Bay Estuary were impaired for nitrogen. Under the Clean Water …


United States Food Law Update: Health Care Reform, Preemption, Labeling Claims And Unpaid Interns: The Latest Battles In Food Law, A. Bryan Endres, Nicholas R. Johnson, Michaela N. Tarr Dec 2010

United States Food Law Update: Health Care Reform, Preemption, Labeling Claims And Unpaid Interns: The Latest Battles In Food Law, A. Bryan Endres, Nicholas R. Johnson, Michaela N. Tarr

Journal of Food Law & Policy

This edition of the Food Law Update explores four legal issues arising in the first half of 2010 reflective of the diverse nature of the food law specialist. As the national debate surrounding the merits of health care reform dominated the legislative agenda, this article first will discuss the food labeling rules embedded within section 4205 of the Patient Protection and Affordable Care Act of 2010. The authors then analyze the preemptive reach of the Federal Food, Drug, and Cosmetic Act and the Meat Inspection Act with respect to three separate California statutes regarding animal welfare standards, retail labels on …


How Communist Is North Korea?: From The Birth To The Death Of Marxist Ideas Of Human Rights, Jiyoung Song Dec 2010

How Communist Is North Korea?: From The Birth To The Death Of Marxist Ideas Of Human Rights, Jiyoung Song

Research Collection School of Social Sciences

This article focuses on the Marxist characteristics of North Korea in its interpretation of human rights. The author's main argument is that many Marxist features pre-existed in Korea. Complying with Marxist orthodoxy, North Korea is fundamentally hostile to the notion of human rights in capitalist society, which existed in the pre-modern Donghak (Eastern Learning) ideology. Rights are strictly contingent upon one's class status in North Korea. However, the peasants' rebellion in pre-modern Korea was based on class consciousness against the ruling class. The supremacy of collective interests sees individual claims for human rights as selfish egoism, which was prevalent in …


Economic Impact Of The University Of Texas‐Pan American, University Of Texas-Pan American Dec 2010

Economic Impact Of The University Of Texas‐Pan American, University Of Texas-Pan American

UTPA Archives - Stats At A Glance

This study was conducted to determine the economic and social impacts of The University of Texas-Pan American (UTPA) on McAllen-Edinburg-Mission Metropolitan Statistical Area’s (MSA) economy.


Newbery Award Winning Books 1975–2009: How Do They Portray Disabilities?, Melissa Leininger, Tina Taylor, Mary Anne Prater, Melissa Allen Heath Dec 2010

Newbery Award Winning Books 1975–2009: How Do They Portray Disabilities?, Melissa Leininger, Tina Taylor, Mary Anne Prater, Melissa Allen Heath

Faculty Publications

Newbery books represent quality literature that has a profound social-emotional impact on its readers, yet these books have not been systematically evaluated for their portrayal of characters with disabilities. Thirty-one Newbery Award and Honor books from 1975–2009 were identified and portrayed 41 main or supporting characters with disabilities. These books were evaluated using the Rating Scale for Quality Characterizations of Individuals with Disabilities in Children’s Literature. Results indicate the representation of Newbery characters with disabilities is not proportionate to the current U.S. population of students with disabilities. Further, racial representation portrayed in these books is not representative of the diverse …


Geophysics At The Interface: Response Of Geophysical Properties To Solid-Fluid, Fluid-Fluid, And Solid-Solid Interfaces, Rosemary Knight, Laura J. Pyrak-Nolte, Lee D. Slater, Estella A. Atekwana, Anthony L. Endres, Jil T. Geller, David P. Lesmes, Seiji Nakagawa, Andre Revil, Mukul M. Sharma, Christian Straley Dec 2010

Geophysics At The Interface: Response Of Geophysical Properties To Solid-Fluid, Fluid-Fluid, And Solid-Solid Interfaces, Rosemary Knight, Laura J. Pyrak-Nolte, Lee D. Slater, Estella A. Atekwana, Anthony L. Endres, Jil T. Geller, David P. Lesmes, Seiji Nakagawa, Andre Revil, Mukul M. Sharma, Christian Straley

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Laboratory studies reveal the sensitivity of measured geophysical properties to solid-fluid, fluid-fluid, and solid-solid interfaces in granular and fractured materials. In granular materials, electrical properties and nuclear magnetic resonance relaxation times exhibit a strong dependence on the size and properties of the solid-fluid interface. The electrical and seismic properties of granular materials and the seismic properties of fractured materials reveal a dependence on the size or geometry of fluid-fluid interfaces. Seismic properties of granular and fractured materials are affected by the effective stress and cementing material at solid-solid interfaces. There have been some recent studies demonstrating the use of field-scale …


Elucidating Functional Roles For Myogenin In Adult Skeletal Muscle Metabolism, Exercise Capacity, And Regeneration, Jesse Flynn Dec 2010

Elucidating Functional Roles For Myogenin In Adult Skeletal Muscle Metabolism, Exercise Capacity, And Regeneration, Jesse Flynn

Dissertations and Theses (Open Access)

The four basic helix-loop-helix myogenic transcription factors, myogenin, Myf5, MRF4, and MyoD are critical for embryonic skeletal muscle development. Myogenin is necessary for the terminal differentiation of myoblasts into myofibers during embryogenesis, but little is known about the roles played by myogenin in adult skeletal muscle function and metabolism. Furthermore, while metabolism is a well-studied physiological process, how it is regulated at the transcriptional level remains poorly understood. In this study, my aim was to determine the function of myogenin in adult skeletal muscle metabolism, exercise capacity, and regeneration. To investigate this, I utilized a mouse strain harboring the Myogflox …


The Immune Inhibitor A1 Protease Of Bacillus Anthracis, Kathryn Pflughoeft Dec 2010

The Immune Inhibitor A1 Protease Of Bacillus Anthracis, Kathryn Pflughoeft

Dissertations and Theses (Open Access)

Bacillus anthracis, an organism ubiquitous in the soil and the causative agent of anthrax, utilizes multiple mechanisms to regulate secreted factors; one example is the activity of secreted proteases. One of the most abundant proteins in the culture supernates of B. anthracis is the Immune Inhibitor A1 (InhA1) protease. Here, I demonstrate that InhA1 modulates the abundance of approximately half of the proteins secreted into the culture supernates, including substrates that are known to contribute to the ability of the organism to cause virulence. For example, InhA1 cleaves the anthrax toxin proteins, PA, LF, and EF. InhA1 also targets …


Stress-Induced Targeting Of Molecular Chaperones In The Yeast Saccharomyces Cerevisiae, Hugo Tapia Dec 2010

Stress-Induced Targeting Of Molecular Chaperones In The Yeast Saccharomyces Cerevisiae, Hugo Tapia

Dissertations and Theses (Open Access)

The eukaryotic stress response is an essential mechanism that helps protect cells from a variety of environmental stresses. Cell death can result if cells are not able to properly adapt and protect themselves against adverse stress conditions. Failure to properly deal with stress has implications in human diseases including neurodegenerative disorders and distinct cancers, emphasizing the importance of understanding the eukaryotic stress response in detail. As part of this response, expression of a battery of heat shock proteins (HSP) is induced, which act as molecular chaperones to assist in the repair or triage of unfolded proteins. The 90-kDa HSP (Hsp90) …


Plasmacytoid Dendritic Cells Sense Skin Injury And Promote Wound Healing Through Type I Interferons, Josh D. Gregorio Dec 2010

Plasmacytoid Dendritic Cells Sense Skin Injury And Promote Wound Healing Through Type I Interferons, Josh D. Gregorio

Dissertations and Theses (Open Access)

Plasmacytoid dendritic cells (pDCs) are a rare population of circulating cells, which selectively express intracellular Toll-like receptors (TLR)-7 and TLR-9 and have the capacity to produce large amounts of type I IFNs (IFN-a/b) in response to viruses or host derived nucleic acid containing complexes. pDCs are normally absent in skin but accumulate in the skin of psoriasis patients where their chronic activation to produce IFN-a/b drives the disease formation. Whether pDCs and their activation to produce IFN-a/b play a functional role in healthy skin is unknown. Here we show that pDCs are rapidly and transiently recruited into healthy human and …


The Role Of Post-Translation Regulation Of Twist Expression In The Tumor Progression Of Squamous Cell Carcinoma Of Head And Neck, Ying-Wen Su Dec 2010

The Role Of Post-Translation Regulation Of Twist Expression In The Tumor Progression Of Squamous Cell Carcinoma Of Head And Neck, Ying-Wen Su

Dissertations and Theses (Open Access)

Squamous cell carcinoma of head and neck (SCCHN) is the tenth most common cancer in the world. Unfortunately, the survival of patients with SCCHN has not improved in the last 40 years. Therefore new targets for therapy are needed, and to this end we are studying signaling pathways activated by IL-6 which we have found stimulates cell migration and soft agar growth in SCCHN. Our data show that IL-6 increases TWIST expression in a transcription-independent mechanism in many SCCHN cell lines. Further investigation reveals TWIST can be phosphorylated upon IL-6 treatment. By computation prediction (http://scansite.mit.edu/motifscan_seq.phtml ), we found that TWIST …


Network To Pology In Human Protein Interaction Data Predicts Functional Association, Hua Li Dec 2010

Network To Pology In Human Protein Interaction Data Predicts Functional Association, Hua Li

Dissertations and Theses (Open Access)

High-throughput assays, such as yeast two-hybrid system, have generated a huge amount of protein-protein interaction (PPI) data in the past decade. This tremendously increases the need for developing reliable methods to systematically and automatically suggest protein functions and relationships between them. With the available PPI data, it is now possible to study the functions and relationships in the context of a large-scale network. To data, several network-based schemes have been provided to effectively annotate protein functions on a large scale. However, due to those inherent noises in high-throughput data generation, new methods and algorithms should be developed to increase the …


Characterization Of The Agrobacterium Tumefaciens Virb2 Pilin Of The Virb/D4 Type Iv Secretion System, Jennifer Kerr Dec 2010

Characterization Of The Agrobacterium Tumefaciens Virb2 Pilin Of The Virb/D4 Type Iv Secretion System, Jennifer Kerr

Dissertations and Theses (Open Access)

The Agrobacterium tumefaciens VirB/D4 type IV secretion system (T4SS) delivers oncogenic T-DNA and effector proteins to susceptible plant cells. This leads to the formation of tumors termed Crown Galls. The VirB/D4 T4SS is comprised of 12 subunits (VirB1 to VirB11 and VirD4), which assemble to form two structures, a secretion channel spanning the cell envelope and a T-pilus extending from the cell surface. In A. tumefaciens, the VirB2 pilin subunit is required for assembly of the secretion channel and is the main subunit of the T-pilus. The focus of this thesis is to define key reactions associated with the T4SS …


Agrobacterium Virb10 Contributions To Type Iv Substrate Secretion, T-Pilus Biogenesis, And Outer Membrane Pore Formation, Isaac Garza Dec 2010

Agrobacterium Virb10 Contributions To Type Iv Substrate Secretion, T-Pilus Biogenesis, And Outer Membrane Pore Formation, Isaac Garza

Dissertations and Theses (Open Access)

The VirB/D4 type IV secretion system (T4SS) of Agrobacterium tumefaciens functions to transfer substrates to infected plant cells through assembly of a translocation channel and a surface structure termed a T-pilus. This thesis is focused on identifying contributions of VirB10 to substrate transfer and T-pilus formation through a mutational analysis. VirB10 is a bitopic protein with several domains, including a: (i) cytoplasmic N-terminus, (ii) single transmembrane (TM) α-helix, (iii) proline-rich region (PRR), and (iv) large C-terminal modified β-barrel. I introduced cysteine insertion and substitution mutations throughout the length of VirB10 in order to: (i) test a predicted transmembrane topology, (ii) …


Analyzing The Role Of Αvβ8 Integrin In Glioma-Induced Angiogenesis, Jeremy H. Tchaicha Dec 2010

Analyzing The Role Of Αvβ8 Integrin In Glioma-Induced Angiogenesis, Jeremy H. Tchaicha

Dissertations and Theses (Open Access)

In this study we aimed to determine the functional roles for αvβ8 integrin in astrocytoma-induced angiogenesis. These studies originate from our analyses of αvβ8 integrin in developmental brain angiogenesis. αv and β8 knockout (KO) mice develop brain-specific vascular phenotypes that resemble vascular pathologies observed in the malignant astrocytoma, glioblastoma multiforme (GBM). Indeed, a murine xenograft model of astrocytoma suggested a role for the integrin in glioma-induced angiogenesis. Primary mouse astroglia were cultured from wild type (WT) and β8 KO neonates and were immortalized (HPV:E6/E7) and transformed (HRas:G12V). WT and β8 KO transformed astroglia were intracranially injected into athymic mice. WT …


Elucidating The Role Of Cd44 Expression On Mesenchymal Stem Cells Within The Tumor Microenvironment, Erika L. Spaeth Dec 2010

Elucidating The Role Of Cd44 Expression On Mesenchymal Stem Cells Within The Tumor Microenvironment, Erika L. Spaeth

Dissertations and Theses (Open Access)

The tumor microenvironment is comprised of a vast array of heterogeneous cells including both normal and neoplastic cells. The tumor stroma recruitment process has been exploited for an effective gene delivery technique using bone marrow derived MSC. Targeted migration of the MSC toward the tumor microenvironment, while successful, is not yet fully understood. This study was designed to assess the role of CD44 in the migration of MSC toward the tumor microenvironment and to determine the implications of CD44-deficient MSC within the tumor stroma. Inhibition of MSC migration was evaluated through a variety of methods in vitro and in vivo …


14-3-3sigma Negatively Regulates The Stability And Subcellular Localization Of Cop1, Chun-Hui Su Dec 2010

14-3-3sigma Negatively Regulates The Stability And Subcellular Localization Of Cop1, Chun-Hui Su

Dissertations and Theses (Open Access)

Mammalian constitutive photomorphogenic 1 (COP1), a p53 E3 ubiquitin ligase, is a key negative regulator for p53. DNA damage leads to the translocation of COP1 to the cytoplasm, but the underlying mechanism remains unknown. We discovered that 14-3-3σ controlled COP1 subcellular localization and protein stability. Investigation of the underlying mechanism suggested that, upon DNA damage, 14-3-3σ bound to phosphorylated COP1 at S387, resulting in COP1 translocation to the cytoplasm and cytoplasmic COP1 ubiquitination and proteasomal degradation. 14-3-3σ targeted COP1 for degradation to prevent COP1-mediated p53 degradation, p53 ubiquitination, and p53 transcription repression. COP1 expression promoted cell proliferation, cell transformation, and …


Dynamic Remodeling Of The Stressed Heart: Role Of Protein Degradation Pathways, Deborah Vela Dec 2010

Dynamic Remodeling Of The Stressed Heart: Role Of Protein Degradation Pathways, Deborah Vela

Dissertations and Theses (Open Access)

The heart is a remarkable organ. In order to maintain its function, it remodels in response to a variety of environmental stresses, including pressure overload, volume overload, mechanical or pharmacological unloading and hormonal or metabolic disturbances. All these responses are linked to the inherent capacity of the heart to rebuild itself. Particularly, cardiac pressure overload activates signaling pathways of both protein synthesis and degradation. While much is known about regulators of protein synthesis, little is known about regulators of protein degradation in hypertrophy. The ubiquitin-proteasome system (UPS) selectively degrades unused and abnormal intracellular proteins. I speculated that the UPS may …


Effects Of Combined Bevacizumab And Paclitaxel On Tumor Interstitial Fluid Pressure In A Preclinical Breast Cancer Model, Ricardo Hugo Alvarez Dec 2010

Effects Of Combined Bevacizumab And Paclitaxel On Tumor Interstitial Fluid Pressure In A Preclinical Breast Cancer Model, Ricardo Hugo Alvarez

Dissertations and Theses (Open Access)

Effects of Combined Bevacizumab and Paclitaxel on Tumor Interstitial Fluid Pressure in a Preclinical Breast Cancer Model by Ricardo H. Alvarez Several mechanisms of cell resistance are often accountable for unsuccessful chemotherapy against cancer. Another reason, which has received increased attention, is the inefficient transport of anticancer drugs into tumor tissue. These impaired transports of chemotherapy into the tumor have been attributed to abnormal microvasculature and to pathologically increased tumor hypertension also called: interstitial fluid pressure (IFP). The pathophysiological processes leading to elevated tumor IFP are poorly understood. Here, in a preclinical breast cancer model, it is argued that a …


Mcam/Muc18 Regulates Melanoma Progression By Modulating The Expression Of Id-1, Maya Zigler Dec 2010

Mcam/Muc18 Regulates Melanoma Progression By Modulating The Expression Of Id-1, Maya Zigler

Dissertations and Theses (Open Access)

The acquisition of the metastatic melanoma phenotype is associated with increased expression of the melanoma cell adhesion molecule MCAM/MUC18 (CD146). However, the mechanism by which MUC18 contributes to melanoma metastasis remains unclear. Herein, we stably silenced MUC18 expression utilizing lentivirus-incorporated small hairpin RNA, in two metastatic melanoma cell lines, A375SM and C8161, and conducted cDNA microarray analysis. We identified and validated that the transcriptional regulator, Inhibitor of DNA Binding-1 (Id-1), previously shown to function as an oncogene in several malignancies, was downregulated by 5.6-fold following MUC18 silencing. Additionally, we found that MUC18 regulated Id-1 expression at the transcriptional level via …


Is Punishment Relevant After All? A Prescription For Informing Juries Of The Consequences Of Conviction, Jeffrey Bellin Dec 2010

Is Punishment Relevant After All? A Prescription For Informing Juries Of The Consequences Of Conviction, Jeffrey Bellin

Vanderbilt Law School Faculty Publications

The American jury, once heralded as "the great corrective of law in its actual administration," has suffered numerous setbacks in the modern era. As a result, jurors have largely become bystanders in a criminal justice system that relies on increasingly severe punishments to incarcerate tens of thousands of offenders each year. The overwhelming majority of cases are resolved short of trial and, even when trials occur, jurors are instructed to find only the facts necessary for legal guilt. Apart from this narrow task, jurors need not, in the eyes of the law, concern themselves with whether a conviction and subsequent …


Policy Relevant Heterogeneity In The Value Of Statistical Life: New Evidence From Panel Data Quantile Regressions, W. Kip Viscusi, Thomas J. Kniesner, James P. Ziliak Dec 2010

Policy Relevant Heterogeneity In The Value Of Statistical Life: New Evidence From Panel Data Quantile Regressions, W. Kip Viscusi, Thomas J. Kniesner, James P. Ziliak

Vanderbilt Law School Faculty Publications

We examine differences in the value of statistical life (VSL) across potential wage levels in panel data using quantile regressions with intercept heterogeneity. Latent heterogeneity is econometrically important and affects the estimated VSL. Our findings indicate that a reasonable average cost per expected life saved cut-off for health and safety regulations is $7 million to $8 million per life saved, but the VSL varies considerably across the labor force. Our results reconcile the previous discrepancies between hedonic VSL estimates and the values implied by theories linked to the coefficient of relative risk aversion. Because the VSL varies elastically with income, …


Impeachment And Assassination, Josh Chafetz Dec 2010

Impeachment And Assassination, Josh Chafetz

Cornell Law Faculty Publications

In 1998, the conservative provocateur Ann Coulter made waves when she wrote that President Clinton should be either impeached or assassinated. Coulter was roundly - and rightly - condemned for suggesting that the murder of the President might be justified, but her conceptual linking of presidential impeachment and assassination was not entirely unfounded. Indeed, Benjamin Franklin had made the same linkage over two hundred years earlier, when he noted at the Constitutional Convention that, historically, the removal of “obnoxious” chief executives had been accomplished by assassination. Franklin suggested that a proceduralized mechanism for removal - impeachment - would be preferable. …