Digital Commons Network^™

Conformation Dependent Monoclonal Antibodies Distinguish Different Replicating Strains Or Conformers Of Prefibrillar Aβ Oligomers, Rakez Kayed, Isabel Canto, Leonid Breydo, Suhail Rasool, Tamas Lukacsovich, Jessica Wu, Ricardo Albay, Anna Pensalfini, Stephen Yeung, Elizabeth Head, J. Lawrence Marsh, Charles Glabe

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary pathological species of protein aggregates.

RESULTS: We have produced several monoclonal antibodies that specifically recognize prefibrillar oligomers and do not recognize amyloid fibrils, monomer or natively folded proteins. Like the polyclonal antisera, the individual monoclonals recognize generic epitopes that do not depend on a specific linear amino acid sequence, but they display distinct preferences for different subsets of prefibrillar oligomers. Immunological …

Volcanic Stratigraphy And A Kinematic Analysis Of Ne-Trending Faults Of Allens Ranch 7.5' Quadrangle, Utah County, Utah, Adam Paul Mckean

Theses and Dissertations

The mineral resources of the Tintic Mining District are influenced by three major events in its geologic history; the Mesozoic Sevier Orogeny, Paleogene volcanism and Late Neogene Basin and Range extension. In this paper a detailed analysis of each these geologic events is presented to help us understand the structural host, mineralization and exhumation of the Tintic Mining District ore. A kinematic analysis of the faults was completed to determine the origin of NE-trending faults, Sevier Orogeny or Basin and Range extension, in the northern part of the East Tintic Mountains in Allens Ranch 7.5' quadrangle, near the eastern margin …

Trusted Mobile Overlays, Robert Scott Robertson

Theses and Dissertations

Sensitive information is increasingly moving online and as data moves further from the control of its owner, there are increased opportunities for it to fall into malicious hands. The Web is comprised of three untrusted components where there is a risk of information compromise: networks, service providers, and clients. This thesis presents Trusted Mobile Overlays: a system that leverages trusted mobile devices to protect users from these untrusted components of the Web, while minimizing deployment difficulties. It presents a high-level design of the system as well as a prototype that implements the design.

Usa V. Frank Caple

2010 Decisions

USDC for the Middle District of Pennsylvania

The Bg News December 13, 2010, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. December 13, 2010. Volume 101-Issue 74.

Identifying The Quantum Correlations In Light-Harvesting Complexes, Kamil Brádler, Mark M. Wilde, Sai Vinjanampathy, Dmitry B. Uskov

Faculty Publications

One of the major efforts in the quantum biological program is to subject biological systems to standard tests or measures of quantumness. These tests and measures should elucidate whether nontrivial quantum effects may be present in biological systems. Two such measures of quantum correlations are the quantum discord and the relative entropy of entanglement. Here, we show that the relative entropy of entanglement admits a simple analytic form when dynamics and accessible degrees of freedom are restricted to a zero- and single-excitation subspace. We also simulate and calculate the amount of quantum discord that is present in the Fenna-Matthews-Olson protein …

Top Quark Mass Measurement In The Lepton+Jets Channel Using A Matrix Element Method And In Situ Jet Energy Calibration, T. Aaltonen, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, J. A. Appel, A. Apresyan, T. Arisawa, A. Artikov, J. Asaadi, W. Ashmanskas, B. Auerbach, A. Aurisano, F. Azfar, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, P. Barria, P. Bartos, M. Bauce, G. Bauer, F. Bedeschi, D. Beecher, S. Behari

Faculty Publications

A precision measurement of the top quark mass mt is obtained using a sample of tt̄ events from pp̄ collisions at the Fermilab Tevatron with the CDF II detector. Selected events require an electron or muon, large missing transverse energy, and exactly four high-energy jets, at least one of which is tagged as coming from a b quark. A likelihood is calculated using a matrix element method with quasi-Monte Carlo integration taking into account finite detector resolution and jet mass effects. The event likelihood is a function of mt and a parameter ΔJES used to calibrate the jet energy scale …

Improved Search For A Higgs Boson Produced In Association With Z→L+L- In Pp̄ Collisions At √S=1.96tev, T. Aaltonen, B. Álvarez González, S. Amerio, D. Amidei, A. Anastassov, A. Annovi, J. Antos, G. Apollinari, J. A. Appel, A. Apresyan, T. Arisawa, A. Artikov, J. Asaadi, W. Ashmanskas, B. Auerbach, A. Aurisano, F. Azfar, W. Badgett, A. Barbaro-Galtieri, V. E. Barnes, B. A. Barnett, P. Barria, P. Bartos, M. Bauce, G. Bauer, F. Bedeschi, D. Beecher, S. Behari

Faculty Publications

We search for the standard model Higgs boson produced with a Z boson in 4.1fb⊃-1 of integrated luminosity collected with the CDF II detector at the Tevatron. In events consistent with the decay of the Higgs boson to a bottom-quark pair and the Z boson to electrons or muons, we set 95% credibility level upper limits on the ZH production cross section multiplied by the H→bb̄ branching ratio. Improved analysis methods enhance signal sensitivity by 20% relative to previous searches. At a Higgs boson mass of 115GeV/c2 we set a limit of 5.9 times the standard model cross section. © …

December 13, 2010 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Evaluation Of Be Wise About Your Portion Size: A Nutrition Education Program For Floridians, Andrea C. Goosen, Laura K. Guyer, Linda B. Bobroff

Florida Public Health Review

In the U.S., obesity is recognized as a growing epidemic whose increased prevalence among adults, children and adolescents present major health concerns. It is the second leading cause of preventable death, surpassed only by tobacco use. Research indicates that controlling the portion sizes of food is an effective way to lose and maintain weight loss. The nutrition education program, “Be Wise about Your Portion Size (BWPS),” was developed in 2005 by the Florida Interagency Food and Nutrition Committee (FIFNC) to support the efforts of community-based nutrition educators. The resource manual provides background information about obesity, consumer handouts, and lesson plans …

Web-Based Ide To Create Model And Controller Components For Mvc-Based Web Applications On Cakephp, Sugiharto Widjaja

Master's Projects

A Web-based IDE that allows users to easily manage Model and Controller components of a CakePHP web application was developed. With this IDE, users are able to manage the model and controller components without having to write very much PHP code. They are able to create new model components without having to worry about creating the database tables for the models as the IDE creates them automatically. The IDE offers a simple interface for users to edit the schema of their models. Users can add or delete data from their models without dealing with the SQL insert/delete statements. The IDE …

Unh-Led Experiment Hurtled Into Aurora Above Norway By Nasa Rocket, David Sims

Media Relations

No abstract provided.

Florida Sentinel Bulletin, December 13, 2010, Gwen Hayes

Florida Sentinel Bulletin Collection

The December 13, 2010, issue of the Florida Sentinel Bulletin.

Hill, Elighu Eldrid, Bronx African American History Project

Oral Histories

Interviewee: Eldrid Hill

Interviewer: Dr. Mark Niason, Ricardo Soto-Lopez, Dana Driskell

Summarized by Sheina Ledesma

Eldrid Hill is a former lieutenant of the New York City Fire Department who has been a long time resident of both Harlem and the Bronx. He has also been deeply involved in local politics and urban planning and a member of Community Board 3 in the Bronx for several decades. Hill was born on July 12, 1928 in Harlem. His mother was from the Dutch side of the island of St. Martin while his father was from St. Kitts. His father was an alcoholic …

Patterns Of Social Activity Engagement Among Older Hispanics And Their Relationship To Sociodemographic And Health Variables, Marta B. Rodríguez-Galán, Luis M. Falcón

Sociology Faculty/Staff Publications

The purpose of this study was to examine patterns of social activity engagement in a sample of older Hispanics (Puerto Rican, Dominican, and other Hispanic) and determine whether these patterns differed significantly from the comparison non-Hispanic White group. This article also analyzes how ethnicity, sociodemographic, and health variables (health problems and depression) relate to each of the activity engagement patterns. The factor analysis of social activities from the Norbeck Social Support Questionnaire yielded three factors, which describe engagement in social activities as: children and relatives active, friends and activities active, and senior services active. The results from the regression analyses …

The Roles Of Elevated Bcl-2 In Ovarian Cancer, Nicole Shree Anderson

USF Tampa Graduate Theses and Dissertations

Ovarian cancer (OC) is the second most common gynecologic cancer; however it is responsible for the most gynecologic cancer-related deaths. Apoptosis evasion is an important mechanism in OC tumorigenesis, and the prototypic anti-apoptotic protein, B-cell lymphoma 2 (Bcl-2), is often overexpressed in OC tumors. Gaining a better understanding of the mechanism(s) behind Bcl-2 overexpression and potential extra-anti-apoptotic functions of Bcl-2 could elucidate the importance of elevated Bcl-2 in OC. In the current study, I show through immunohistochemical analysis of normal, benign, and OC tissue sections, that both epithelial and stromal Bcl-2 expression decreases with OC progression. However, the number of …

Draft Direct Service Core Competencies, Eileen M. Brennan, Pauline Jivanjee, Eliz Roser

Regional Research Institute for Human Services

At the first quarterly meeting of the Pathways Transition Training Collaborative (PTTC), members approved the following definition of competency, and the structure of the core competency document. The definition is based in part on the work of Hoge, Tondora, and Marrelli (2005). We will be developing an interdisciplinary course for graduate students based on the core competencies that emerge from the PTTC and the research of the Pathways to Positive Futures RTC. Later, the PTTC will present webinar and online course modules that develop from the core competencies identified by our community of practice.

Commodity Trade Potential In Tanzania: What Went Wrong With The Mineral Sector?, Petro Sauti Magai

Business Management Review

This paper analyses the facts causing the mineral sector to make less of a contribution to the country ' s economy. Although the sector accounts for nearly half of the country ' s exports, ordinary Tanzanians are not benefiting from this because the government has implemented tax laws that overly favour multinational mining companies. Companies claim to make loss and so avoid paying taxes although they still invest in the country The system is also perceived to be lacking transparency. It is argued that the combined loss to the country is a result of low royalty rates, unpaid corporation taxes …

Determination Of Level Of Imports In The Construction Industry In Tanzania, Robert Suphian

Business Management Review

The construction industry has to be competitive and be able to undertake most of the construction projects in Tanzania and export its services and product according to the Tanzania construction policy. This is contrary to the fact that the industry is dominated by Foreign Service providers to the tune of approximately 70 percent in terms of market share. This study employed an econometric model estimation to answer the question of what determined import for construction services in Tanzania for the period 1985-2008. The Ordinary Least Square technique was adopted and applied for regression analysis using Stata 10 software. The findings …

Demand For Accountants In Botswana: Views Of Employers, Christian J. Mbekomize

Business Management Review

The objective of this study was to explore the problem of shortage of accountants in Botswana in order to establish which types of accountants are in short supply, identify the sector of the economy which has been most affected by the shortage and find out how this shortage could be curtailed. A survey of the views of employers of accountants revealed the vacancy rate of professional accountants in Botswana as 15% of the establishment, with that the ratio of local to expatriate accountants about 1:1. These findings do not support the findings by the Botswana Institute of Accountants in 2009, …

Monitoring Soil Quality To Assess The Sustainability Of Harvesting Corn Stover, Douglas L. Karlen, Gary E. Varvel, Jane M.F. Johnson, John M. Baker, Shannon L. Osborne, Jeff M. Novak, Paul R. Adler, Greg W. Roth, Stuart J. Birrell

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Harvesting feedstock for biofuel production must not degrade soil, water, or air resources. Our objective is to provide an overview of field research being conducted to quantify effects of harvesting corn (Zea mays L.) stover as a bioenergy feedstock. Coordinated fi eld studies are being conducted near Ames, IA; St. Paul and Morris, MN; Mead, NE; University Park, PA; Florence, SC; and Brookings, SD., as part of the USDA-ARS Renewable Energy Assessment Project (REAP). A baseline soil quality assessment was made using the Soil Management Assessment Framework (SMAF). Corn grain and residue yield for two diff erent stover harvest rates …

Board Of Directors Meeting Minutes (December 13, 2010), Dmacc

Board of Directors Meeting Minutes

This file contains the minutes from the Des Moines Area Community College Board meeting held on December 13, 2010.

Petals: Proteomic Evaluation And Topological Analysis Of A Mutated Locus' Signaling, Gurkan Bebek, Vishal Patel, Mark R. Chance

Faculty Scholarship

Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified over the years, it is not always clear which functions or interactions are operative in a particular tumor. This is confounded by the presence of mutations in a number of other putative cancer driver (CAN) genes, which often synergize with mutations in Apc.Computational methods are, thus, required to predict which pathways are likely to be operative when a particular mutation in Apc is observed.Results: We developed a pipeline, PETALS, to predict and …

The Function Of Narrative In Leadership: Theoretical Foundations And Empirical Evidence, Michael S. Carriger

WCBT Faculty Publications

This research is focused on the differential impacts of narrative and facts and figures on the understanding of corporate strategy or competitive advantage. In this way a theoretical (philosophical) foundation can be laid for narrative and the understanding of corporate strategy. Additionally, much needed theoretically sound, empirical validation can be offered for the use of narrative and storytelling by leaders within organizations as a means of creating, disseminating,and executing strategy. Employing a model derived from the tension between modern and post-modern thinking about the nature of ideas and concepts a conceptual framework is offered to try to explain the possible …

Lanthorn, Vol. 45, No. 31, December 13, 2010, Grand Valley State University

Volume 45, July 8, 2010 - June 9, 2011

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Gender Differences In Resilience In The Emerging Adulthood Population, Erin Bezek

Theses

Risk factors and protective factors influence an individual's resilience. For this study archival data collected from Rochester Institute of Technology college students were used. Specifically the participants' responses on the 16PF- Adolescent Personality Questionnaire (APQ) Life Difficulties Scale (LDS) were analyzed. After reconfiguring the Life Difficulties Scale using the literature review to analyze the items, results indicated that specific items can be considered risk factors, whereas others can be considered protective factors. Results from this emerging adulthood population did not indicate gender differences in the risk and protective factors.

Dihomotopic Deadlock Detection Via Progress Shell Decomposition, David A. Cape, Stephen C. Jackson, Bruce M. Mcmillin

Computer Science Faculty Research & Creative Works

The classical problem of deadlock detection for concurrent programs has traditionally been accomplished by symbolic methods or by search of a state transition system. This work examines an approach that uses geometric semantics involving the topological notion of dihomotopy to partition the state space into components, followed by search of a reduced state space. Prior work partitioned the state-space inductively. in this work, a decomposition technique motivated by recursion coupled with a search guided by the decomposition is shown to effectively reduce the size of state transition systems. the reduced state space yields asymptotic improvement in overall runtime for verification. …

Deafdigest: Blue Edition, December 12, 2010, Barry Strassler

DeafDigest Blue 2010

No abstract provided.

Memo, Office Of Academic Affairs, 47th Fall 2010 Commencement, December 12, 2010, University Of South Florida St. Petersburg. Office Of Academic Affairs

USF St. Petersburg Graduations and Commencements

Memo from the University of South Florida St. Petersburg's Office of Academic Affairs with logistics information about Fall 2010 commencement.

Criminal Justice Information Sharing: A Legal Primer For Criminal Practitioners In California, W. David Ball, Robert Weisberg

Faculty Publications

California criminal justice agencies need access to data in order to provide security, health care treatment, and appropriate programming, as well as to coordinate these activities with other agencies. By the same token, outside agencies—whether criminal, social service, or non-governmental—could often do their jobs more effectively with access to information generated or retained within particular criminal justice agencies. Criminal justice realignment under AB 109 has only heightened the need for inter-agency data sharing and cooperation, yet there continue to be misunderstandings about the legal framework surrounding information exchange.

This Article aims to provide a basic, practical background on the legal …