Digital Commons Network^™

Remembering The Endangered "Child": Limiting The Definition Of "Safe Haven" And Looking Beyond The Safe Haven Law Framework, Lucinda J. Cornett

Kentucky Law Journal

No abstract provided.

A "Preposterous Anomaly": Sovereign Immunity In Kentucky Following The Crash Of Comair Flight 5191, Nathaniel R. Kissel

Kentucky Law Journal

No abstract provided.

The Anticipation Misconception, Colin P. Marks

Kentucky Law Journal

No abstract provided.

The Disregarding Of The Rehabilitative Spirit Of Juvenile Codes: Addressing Resentencing Hearings In Blended Sentencing Schemes, Grace Shear

Kentucky Law Journal

No abstract provided.

Journeying Toward Humility: Complexities In Advancing Pedagogy For The Privileged, Ann Curry-Stevens

School of Social Work Faculty Publications and Presentations

This narrative describes the author's journey away from a stance of innocence, toward one of humility in her engagement with pedagogy for the privileged. With deep attention to her identity, the contentious dimensions of this pedagogy have compelled her towards a much more troubled relationship with this practice. The following narrative profiles key contributions of pedagogy for the privileged, and articulates the contentions embedded within. It concludes with three essential ingredients to moderate her privilege: practicing from a stance of humility and "not knowing, " advancing research into the practice outcomes of such courses, and accountability structures where communities hold …

The Military Genogram: A Solution-Focused Approach For Resiliency Building In Service Members And Their Families, Eugenia Weiss, Jose Coll, Jennifer Gerbauer, Kate Smiley, Ed Carillo

School of Social Work Faculty Publications and Presentations

In recent decades, it has become evident among mental health practitioners that the military is a unique culture that is comprised of distinct ethics, core values, codes of conduct, and strict hierarchical roles. In light of the war in Afghanistan and the war in Iraq, veterans and their families are seeking mental health services due to a variety of psychosocial issues; however, mental health practitioners are lacking military-specific knowledge in understanding individuals within the military subculture. In addition, they are ill-equipped with interventions aimed at supporting the military family. Historically, the genogram has been an effective tool in delineating intergenerational …

Inter-American System, Claudia Martin

Scholarly Articles in Law Reviews & Journals

No abstract provided.

Healing Through Reading : Bibliotherapy, Cierra Van Treese

Capstone Projects and Master's Theses

For some children the joy and innocence of childhood is cut short when they face, or are overwhelmed by traumatic events. Bibliotherapy seeks to begin and encourage the healing process in children as they relate and connect to characters within a book. Connecting children to appopriate books is one of the most crucial aspects of bibiliotherapy, however, because libraries, books stores and book lists do not organize books by subject, an online resource which provides a list of good, quality books arranged by subject was needed in order for children to be able to explore and connect for themselves. The …

What About Race After Obama: Individualism, Multiculturalism, Or Assimilationism?, John Berteaux

HCOM Faculty Publications and Presentations

I argue that we do not get an adequate picture of society from liberal conceptions of race and racism. What this analysis does, then, is call for a synthesis of historical, social, and cultural insights to inform and enrich the philosophical conception of race and racism.

Prevalence Of Rubella Igg Antibodies Among Syrian Females Of Childbearing Age, Faraj Barah, Amer G. Chehada

Saudi Medical Journal

OBJECTIVE: To examine the current sero-epidemiology of rubella IgG among Syrian females of childbearing age that missed rubella vaccination. METHODS: A cross-sectional study examined healthy female students of the Pharmacy College, Kalamoon University, Deratiah, Syria. Ninety sera were collected between March and May 2008, and were subject to rubella specific IgG screening and titration using an enzyme-linked immunosorbent assay-based technique provided by Diamed Eurogen in the Microbiology Laboratory, Faculty of Pharmacy. RESULTS: The quantitative analysis for rubella IgG showed a noticeable variability in the values of antibodies that ranged between 0-363 IU/ml. A total of 77 participants were positive for …

Gabab Regulation Of Methamphetamine-Induced Associative Learning, Robin Michelle Voigt

Dissertations

Addiction is a chronic, relapsing disorder for which strikingly few effective therapies exist, and there are no FDA-approved pharmacotherapies for methamphetamine (Meth) addition. There is an immense need to identify the neurobiological underpinnings of psychostimulant addiction and develop efficacious drug therapies to compliment the current mainstay treatment of behavioral/cognitive therapy.

Re-exposure to cues associated with psychostimulants (e.g., drug paraphernalia) increase neuronal activity and can elicit drug-craving and -seeking; an effect which is profound and long-lasting. A mechanism to disrupt those brain processes which are necessary to maintain the association may reduce the incidence of cue-elicited relapse.

Conditioned place preference (CPP) …

Polyomavirus Enhancer Activator 3 (Pea3), A Member Of The Ets Family Of Transcription Factors, Is A Transcriptional Activator Of Notch-1 And Notch-4 In Breast Cancer: An Opportunity For Novel Combinational Therapy, Anthony George Clementz

Dissertations

Women diagnosed with triple-negative breast cancer have the worst overall prognosis and frequently present with metastatic tumors. To date, there are no targeted therapies available to combat this aggressive form of breast cancer due to the lack of expression of well-known targets such as ER-alpha, PR, or HER2/neu. Therefore, there is an immediate need to identify novel targets that are responsible for the proliferation, survival, and invasive phenotype. Notch-1 and Notch-4, both potent breast oncogenes, are overexpressed in triple-negative breast cancers-associated with the poorest overall survival. PEA3 (polyomavirus enhancer activator 3), a member of the Ets family of transcription factors, …

Humanity In The Balance: The Relationship Between The Moral Law And The Promotion Of The Moral World In Kant's Ethics, John J. Garcia

Dissertations

This dissertation deals with the tension between two seemingly divergent approaches to morality. On the one hand, there are those who take the view that morality concerns itself with the promotion of certain ends. This is a teleological or consequentialist view of ethics. On the other hand, we see thinkers who take the view that rationality or some other criteria provide us certain moral imperatives that may not be violated, regardless of our desire to bring about a particular end. Kant is usually depicted not only as a member of the latter camp, but indeed as the father of this …

Psychosocial Development, Well-Being, And Internalizing Symptoms During Emerging Adulthood: An Examination Of Mediating And Moderating Factors, Jennifer Paley Edidin

Dissertations

The current study was the second part of a longitudinal study, which sought to explore psychosocial development in an older population of emerging adults. Specifically, it examined cross-sectional and longitudinal relations between psychosocial development and internalizing symptoms, as well as between psychosocial development and well-being. Possible mediating and moderating factors were also considered. Two hundred and twelve eligible individuals from one private Midwestern University and one small private college on the East Coast, who completed measures as college seniors, were invited to participate in the second wave of the study, approximately 1½ years after graduation. Participants were asked to complete …

In Whose Best Interest? Using An Experimental Vignette To Assess Factors Influencing Placement Decisions In Child Welfare, Jeff Sieracki

Dissertations

Building on prior research that utilizes clinical vignettes to analyze child welfare placement decisions (Briar, 1963; Britner & Mossler, 2002; Donnelly, 1980; Drury-Hudson, 1999; Gold, et al., 2001; Taylor, 2006), the present study employs an experimental format to assess the relative importance that social workers place on variables related to placement decisions, and to study any differences regarding decision making that may emerge amongst the child welfare professionals themselves. The study consists of a single hypothetical vignette that will be sent to social workers in the state of Illinois. Prior to administration of the questionnaire, multiple experts in the field …

Review Of Beau Breslin's "From Words To Worlds", Robert L. Tsai

Scholarly Articles in Law Reviews & Journals

No abstract provided.

Using Competition Law To Promote Access To Knowledge, Sean Flynn

Contributions to Books

One of the points of convergence among the many strands of the A2K movement is resistance to the one-size-fits-all ratcheting up of intellectual property provisions around the world. The resistance is grounded in analysis showing that intellectual property rules often create social costs that far outweigh their intended benefits. Much of the A2K movement’s advocacy for limitations of intellectual property rights is located within the field of intellectual property law – promoting the inclusion and use of balancing mechanisms within the laws granting intellectual property rights. But intellectual property rights are also shaped and limited by their interaction with other …

The Role Of A Law School Dean: Balancing A Variety Of Roles And Interests - The American University Washington College Of Law Experience, Claudio Grossman

Scholarly Articles in Law Reviews & Journals

No abstract provided.

The Use Of Protective Behavioral Strategies Is Related To Reduced Risk In Heavy Drinking College Students With Poorer Mental And Physical Health, Joseph W. Labrie, Shannon R. Kenney, Andrew Lac

Heads Up!

The present study examined the moderating role of health status (physical, mental, and social health) and the relationships between protective behavioral strategies utilized to reduce high-risk drinking (e.g., avoiding drinking games, setting consumption limits, or having a designated driver) and alcohol use and negative consequences in a sample of heavy drinking college students (N = 1,820). In this high risk sample, multiple regression analyses showed that stronger social health was related to increased drinking, while poorer physical, mental, and social health were related to increased alcohol negative consequences. Further, moderation effects revealed that increasing the use of protective behaviors …

The Newest Religious Sect Has Started In Los Angeles: Race, Class, Ethnicity, And The Origins Of The Pentecostal Movement, 1906 – 1913, Marne Campbell

African American Studies Faculty Works

No abstract provided.

Fatal Flirting: The Nazi State And The Seventh-Day Adventist Church, Harold Alomía

Journal of Adventist Mission Studies

No abstract provided.

Shaking Hands With The (D)Evil: Adventism And Communism, Cristian Dumitrescu

Journal of Adventist Mission Studies

No abstract provided.

Church And Society In Adventism: Some Reflections, Kwabena Donkor

Journal of Adventist Mission Studies

No abstract provided.

Children At Risk: Key Frontier For Adventist Mission, P. T. Pointe

Journal of Adventist Mission Studies

No abstract provided.

Adventism Among The World Religions, Gary Krause

Journal of Adventist Mission Studies

No abstract provided.

The 5'-7-Methylguanosine Cap On Eukaryotic Mrnas Serves Both To Stimulate Canonical Translation Initiation And To Block An Alternative Pathway, Sarah F. Mitchell

Chemistry and Biochemistry Faculty Works

Translational control is frequently exerted at the stage of mRNA recruitment to the initiating ribosome. We have reconstituted mRNA recruitment to the 43S preinitiation complex (PIC) using purified S. cerevisiae components. We show that eIF3 and the eIF4 factors not only stabilize binding of mRNA to the PIC, they also dramatically increase the rate of recruitment. Although capped mRNAs require eIF3 and the eIF4 factors for efficient recruitment to the PIC, uncapped mRNAs can be recruited in the presence of eIF3 alone. The cap strongly inhibits this alternative recruitment pathway, imposing a requirement for the eIF4 factors for rapid and …

Ribosome Recycling Step In Yeast Cytoplasmic Protein Synthesis Is Catalyzed By Eef3 And Atp, Sarah F. Mitchell

Chemistry and Biochemistry Faculty Works

After each round of protein biosynthesis, the posttermination complex (PoTC) consisting of a ribosome, mRNA, and tRNA must be disassembled into its components for a newround of translation. Here, we show that a Saccharomyces cerevisiae model PoTC was disassembled by ATP and eukaryotic elongation factor 3 (eEF3). GTP or ITP functioned with less efficiency and adenosine 5γ′-(β,γ-imido)triphosphate did not function at all. The kcat of eEF3 was 1.12 min-1, which is comparable to that of the in vitro initiation step. The disassembly reaction was inhibited by aminoglycosides and cycloheximide. The subunits formed from the yeast model PoTC remained separated under …

Delayed Differentiation In Embryonic Stem Cells And Mesodermal Progenitors In The Absence Of Ctbp2, Heather Tarleton

Health and Human Sciences Faculty Works

Mammalian embryonic stem cells (ESCs) are characterized by an ability to self-renew and give rise to each of the three germ layers. ESCs are a pluripotential source of numerous primitive progenitors and committed lineages and can make stoichiometric decisions leading to either asymmetric or symmetric cell division. Several genes have been identified as essential for maintenance of self-renewal, but few non-lineage specific genes have been identified as essential for differentiation. We selected the chromatin factor Ctbp2 from microarray data for its enriched expression in stem cells, in comparison to committed progenitors. RNA interference (RNAi) was used to knockdown gene expression …

Spark-Induced Sparks As A Mechanism Of Intracellular Calcium Alternans In Cardiac Myocytes, Robert J. Rovetti, Xiaohua Cui, Alan Garfinkel, James N. Weiss, Zhilin Qu

Mathematics, Statistics and Data Science Faculty Works

Rationale: Intracellular calcium (Ca) alternans has been widely studied in cardiac myocytes and tissue, yet the underlying mechanism remains controversial.

Objective: In this study, we used computational modeling and simulation to study how randomly occurring Ca sparks interact collectively to result in whole-cell Ca alternans.

Methods and Results: We developed a spatially-distributed intracellular Ca cycling model in which Ca release units (CRUs) are locally coupled by Ca diffusion throughout the myoplasm and sarcoplasmic reticulum (SR) network. Ca sparks occur randomly in the CRU network when periodically paced with a clamped voltage waveform, but Ca alternans develops as the pacing speeds …

Epistemic Malevolence, Jason Baehr

Philosophy Faculty Works

Against the background of a great deal of structural symmetry between intellectual and moral virtue and vice, it is a surprising fact that what is arguably the central or paradigm moral vice—that is, moral malevolence or malevolence proper—has no obvious or well-known counterpart among the intellectual vices. The notion of “epistemic malevolence” makes no appearance on any standard list of intellectual vices; nor is it central to our ordinary ways of thinking about intellectual vice. In this essay, I argue that there is such a thing as epistemic malevolence and offer an account of its basic character and structure. Doing …