Digital Commons Network^™

Risk Of Second Malignant Neoplasm Following Proton Versus Intensity-Modulated Photon Radiotherapies For Hepatocellular Carcinoma, Phillip J. Taddei, Rebecca M. Howell, Sunil Krishnan, Sarah B. Scarboro, Dragan Mirkovic, Wayne D. Newhauser

Faculty Publications

Hepatocellular carcinoma (HCC), the sixthmost common cancer in theworld, is a global health concern. Radiotherapy for HCC is uncommon, largely because of the likelihood of radiation-induced liver disease, an acute side effect that is often fatal. Proton beam therapy (PBT) and intensity-modulated radiation therapy (IMRT)may offer HCC patients a better option for treating the diseased liver tissue while largely sparing the surrounding tissues, especially the nontumor liver. However, even advanced radiotherapies carry a risk of late effects, including second malignant neoplasms (SMNs). It is unclear whether PBT or IMRT confers less risk of an SMN than the other. The purpose …

Report: The Illinois State University Faculty-Staff Newsletter, December 7, 2010, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

Zivkovic V. State Respondent's Brief Dckt. 37287

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Heterosubstituted N-Thiolated Beta-Lactam Compounds And Methods Of Use, Edward Turos, Praveen Ramaraju

USF Patents

The invention relates to heterosubstituted N-thiolated beta-lactams, compositions comprising these compounds, methods for their production, and methods of use as antibiotics to inhibit the growth of bacteria. In one embodiment, the compounds have the structure shown in formula (A) or formula (B) or formula (C):

wherein the R groups are as defined in the specification. The antibacterial agents of the invention can be administered to a human or animal to treat or inhibit bacterial infection, such as that of Staphylococcus species, including methicillin-resistant Staphylococcus aureus (MRSA).

Investigation Of Spatial And Temporal Processes Of Lake–Aquifer Interactions In The Nebraska Sand Hills, John T. Ong

Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research

Interaction between surface water and groundwater is an important component of the water cycle that affects the physicochemical and biological characteristics of lakes, streams, wetlands, and seacoasts. Due to the complex interaction of geologic, topographic, and hydrologic factors, flow between lakes and groundwater remains poorly understood. Evolution of conceptual models over the past 30 years describes processes of advection, dispersion, and free convection that occur in different lake flow regimes. Few detailed field studies document the validity of these conceptual models because of the difficulty of studying the subsurface and the prohibitive cost of instrumenting large areas. In the semi-arid …

Mode-Locked Optical Amplifier As A Source For A Wdm-Wdm Hierarchy Architecture, Peter Delfyett, Thomas Banwell, Shahab Etemad, Stefano Galli, Janet Lehr Jackel, Ronald Menedez, Paul Toliver

UCF Patents

No abstract provided.

The New Hampshire, Vol. 100 [101], No. 24 (Dec. 7, 2010), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 100, but it is the 101st volume in the series. This was corrected in pencil.

The Bg News December 7, 2010, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. December 7, 2010. Volume 101-Issue 70.

The Parthenon, December 7, 2010, Marshall University

The Parthenon

No abstract provided.

Haploinsufficiency Of Rai1 And Its Effect On Bdnf Expression, Sun Kim

Theses and Dissertations

Smith-Magenis Syndrome (SMS) [OMIM, #182290] is a congenital anomaly and mental retardation (MCA/MR) syndrome associated with deletion of chromosome17p11.2 [1]. The clinical phenotype has been well described and includes minor craniofacial anomalies, self-injurious behaviors as well as sleep disturbances, speech delays, and obesity [1,2,3]. The incidence of SMS is estimated to be ~ 1:15,000 - 25,000 births [2,6]. Among SMS patients, ~90% are comprised of 17p11.2 deletions, while ~10% have RAI1 mutations [8]. All 17p11.2 deletions associated with SMS include RAI1 deletion [10]. RAI1 is thought to function as a transcriptional factor although its cellular role is still unclear. First, …

Comparing Administration Of Nutrition Support With Prescribed Dose, Lara Kelley Griffith

Electronic Theses and Dissertations Archive

Objective: To evaluate if pediatric bone marrow transplant (BMT) patients receive the prescribed dose of nutrition support (NS).Design: Data was obtained from electronic and paper charts at St. Jude Children's Research Hospital. Amount of NS received was compared to the amount prescribed. Subjects: Data was collected on 32 patients, for a total of 63 incidences of hospital stays in which nutrition support was administered.Results: Mean percentage of nutrition prescription met and percentage of total estimated energy needs met were 69% and 72%, respectively. Allogenic BMT patients received significantly more of their nutrition prescription (92%) compared to autologous BMT patients (54%), …

Information-Preserving Structures: A General Framework For Quantum Zero-Error Information, Robin Blume-Kohout, Hui Khoon Ng, David Poulin, Lorenza Viola

Dartmouth Scholarship

Quantum systems carry information. Quantum theory supports at least two distinct kinds of information (classical and quantum), and a variety of different ways to encode and preserve information in physical systems. A system’s ability to carry information is constrained and defined by the noise in its dynamics. This paper introduces an operational framework, using information-preserving structures, to classify all the kinds of information that can be perfectly (i.e., with zero error) preserved by quantum dynamics. We prove that every perfectly preserved code has the same structure as a matrix algebra, and that preserved information can always be corrected. We …

Standard Protocols For The 3 Mst Markers Evaluated, Microbial Source Tracking

EPA Study

This protocol outlines the procedure developed for the EPA Gulf of Mexico grant to Harwood, Lepo and Wang to process environmental water samples via DNA extraction from membrane filters. DNA is then used in PCR-based microbial source tracking assays for human-associated Bacteroides (HBac), M. smithii (Msmithii) and human polyomavirus BK and JC (HPyVs) targets.

In Translation V.1:No.2 (2010:Fall), Matthew J. Cook

UCHC Articles - Research

Momentum Continues: Newly Formed CICATS IRB The newly established CICATS Institutional ReviewBoard (IRB), chaired by Julian Ford, PhD, is officially operational. Applications are currently being accepted for review of CICATS research studies and trials. The first convened meeting was held on November 18, 2010.

Research Navigation There are two new members of CICATS available to you in your research investigator corner — the Regulatory Analyst and the Investigator Advocate.

The Gateway Stacey Anderson, Operations Manager The Gateway serves as the primary point of contact for researchers seeking assistance, referral, services and resources. This “nerve center” promotes collaborative clinical and translational …

Spartan Daily December 6, 2010, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 135, Issue 50

Proposed Hsc Governance Regents Policy Revisions, Unm University Counsel

Faculty Senate Documents

Attached is a packet of proposed revised Regents policies pertaining to the HSC Governance reorganization proposal. After careful review, the Policy Office concluded that the earlier format of proposed revisions to Regent Policy 2.13 (which was originally presented to the Regents on November 16, 2010 and integrated a range of policy modifications into a single and very lengthy policy), was confusing and administratively burdensome. Therefore, the previously circulated Regent Policy 2.13 has been replaced by four separate proposed Regent policies, RPM\xa7\xa7 3.4 through 3.7. The general structure of the Health Sciences Center, as well as the role of the new …

Commonwealth Times 2010-12-06

Commonwealth Times, 1969-

No abstract provided.

Mustang Daily, December 6, 2010

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

December 6th 2010, Csusb

Coyote Chronicle (1984-)

No abstract provided.

The Statesman, V. 54, I. 15, Stony Brook University

Stony Brook Statesman-Sucolian

v. 54, i. 15

Current, December 06, 2010, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

December 6, 2010, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Dual Inhibition Of Sodium-Mediated Proton And Calcium Efflux Triggers Non-Apoptotic Cell Death In Malignant Gliomas, William Harley, Candace Floyd, Tamara Dunn, Xiao-Dong Zhang, Tsung-Yu Chen, Manu Hegde, Hasan Palandoken, Michael H. Nantz, Leonardo Leon, K.L. Carraway Iii, Bruce Lyeth, Fredric A. Gorin

Chemistry and Biochemistry

Malignant glioma cells maintain an elevated intracellular pH (pH_i) within hypoxic–ischemic tumormicroenvironments through persistent activation of sodium–proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al., 2004). While amiloride reduces pH_i of malignant gliomas by inhibiting isoform 1 of sodium–proton exchange (NHE1), direct acidification was shown to be cytostatic rather than cytotoxic. At cytotoxic concentrations, amiloride has multiple drug targets including inhibition of NHE1 and sodium–calciumexchange. Amiloride's glioma cytotoxicity can be explained, at least in part, by dual inhibition of NHE1 and …

The Murray Ledger And Times, December 6, 2010, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Sovereignty And Cooperative Management Of Shared Water Resources In A Time Of Shrinking Availability: The Role Of International Law, Stephen C. Mccaffrey

McGeorge School of Law Other Faculty Works

It is a commonplace today that per capita availability of fresh water is shrinking. In addition, it is well known that some 60 per cent of global freshwater flows are contained in the 263 river basins that are shared by two or more countries, and that around 40 per cent of the human population lives in these international basins. These facts underscore the necessity of cooperation between states sharing fresh water, whether it is on the surface or underground. And yet internal political forces often lead countries to maximize their use of shared water resources without considering adequately the needs …

Lanthorn, Vol. 45, No. 29, December 6, 2010, Grand Valley State University

Volume 45, July 8, 2010 - June 9, 2011

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Faculty Senate Agenda, December 6, 2010, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Faculty Evaluation Committee Annual Report
• Athletic Council Annual Report
• EPC Items for October
• EPC Items for November
• ASUSU Annual Report
• Retention and Student Success Annual Report
• Evaluation of Teaching Excellence (Quality Instruction)
• PRPC Section 402.3. - 402.9 The Faculty Senate and Its Committees (Second Reading)
• PRPC Section 405.11.4 (1) Tenured and Term Appointments: Evaluation, Promotion, and Retention (First Reading)

Thinking Differently: Developing A Fall Risk Assessment For The Emergency Department Setting, Carissa K. Fauks

Theses and Graduate Projects

When a patient falls in the hospital it ends up being costly for both the patient and the hospital. Having an awareness of risk factors that lead to an increase in patient falls becomes very important for all nursing staff. However, the contributing factors are not the same for every department in a hospital. The focus of this proposal is the development of a fall assessment that is specific to the emergency department. Age, cognition, elimination, physical mobility, and medications were the risk factors determined to be most important after a review of the literature. Once the fall assessment scale …

The Utah Statesman, December 6, 2010, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Reconstructability Analysis Of Epistasis, Martin Zwick

Complex Systems Faculty Publications and Presentations

The literature on epistasis describes various methods to detect epistatic interactions and to classify different types of epistasis. Reconstructability analysis (RA) has recently been used to detect epistasis in genomic data. This paper shows that RA offers a classification of types of epistasis at three levels of resolution (variable-based models without loops, variable-based models with loops, state-based models). These types can be defined by the simplest RA structures that model the data without information loss; a more detailed classification can be defined by the information content of multiple candidate structures. The RA classification can be augmented with structures from related …