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2010

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Spectral Approaches To Natural Mesh Processing, Takamitsu Kawai Dec 2010

Spectral Approaches To Natural Mesh Processing, Takamitsu Kawai

Graduate Theses, Dissertations, and Problem Reports (ETD)

Mesh design is a major bottleneck in the creation of computer games and animation. Therefore simplifying the process of mesh editing is an important problem. Natural mesh processing is generally difficult to perform since natural meshes often have nontrivial surface shapes and high degrees of freedom. In this study I present novel approaches to natural mesh processing utilizing spectral methods based on the manifold harmonic basis.;Geometric scaling transformations do not respect the biological processes which govern the size and shape of living creatures. I describe an approach to scaling which can be related to biological function. Known biological laws of …


Selective Self-Stereotyping And Women’S Self-Esteem Maintenance, Debra L. Oswald, Kristine M. Chapleau Dec 2010

Selective Self-Stereotyping And Women’S Self-Esteem Maintenance, Debra L. Oswald, Kristine M. Chapleau

Psychology Faculty Research and Publications

The process and implications of gender-based self-stereotyping are examined in this paper. Women displayed a tendency to selectively self-stereotype for personality and physical traits such that they endorsed positive stereotypic traits and denied negative traits as descriptive of the self and closest women friends. However, negative traits were endorsed as descriptive of women in general. Cognitive stereotypes were endorsed as more descriptive of all women than of the general university student. The tendency to selectively self-stereotype on physical traits was positively associated with appearance, social, and performance self-esteem. The results are discussed for their theoretical and practical implications.


Normative Reflectance And Transmittance Measurements On Healthy Newborn And 1-Month-Old Infants, Gabrielle R. Merchant, Nicholas J. Horton, Susan E. Voss Dec 2010

Normative Reflectance And Transmittance Measurements On Healthy Newborn And 1-Month-Old Infants, Gabrielle R. Merchant, Nicholas J. Horton, Susan E. Voss

Engineering: Faculty Publications

Objective:

Ear-canal-based wideband reflectance (WBR) measurements may provide objective measures to assess and monitor middle-ear status in young babies. This work presents WBR measurements of power reflectance and transmittance on populations of healthy newborn babies (3 to 5 days) and healthy 1-mo-old babies (28 to 34 days). Thus, this work determines how power reflectance and transmittance vary between newborn and 1-mo-old babies and characterizes the range of these measures in normal populations.

Design:

Power reflectance and transmittance were calculated from pressure measurements made in the ear canals of seven newborn (12 ears) and eleven 1-mo-old (19 ears) babies. Permutation tests, …


Diabetes Education: Supporting The Pre-Adolescent Child, Janet M. Mattson Dec 2010

Diabetes Education: Supporting The Pre-Adolescent Child, Janet M. Mattson

Theses and Dissertations

A diagnosis of Type I diabetes impacts every aspect of life for the pre-adolescent child. ln order to successfully manage Type J diabetes, the child must learn the complex regimen of its ca re. The responsibility for diabetes se lf-ca re begins to transfer to the child at pre-adolescence. Controlling diabetes is difficult for the pre-adolescent, however, clue to the lack of understanding the complex concepts of this disease and the unique developmental tasks associated with this age group. Diabetes educat ion must support the cogniti ve level and developmental needs of the pre-adolescent. Literature emphasizes the need for age …


Examining The Effectiveness Of Dropout Prevention Practices And Their Implications For Intervention With Public School Students, Louisa Pollack Dec 2010

Examining The Effectiveness Of Dropout Prevention Practices And Their Implications For Intervention With Public School Students, Louisa Pollack

Dissertations

Schools face the dilemma of transforming both the trend of students dropping out of school and the associated negative socioeconomic outcomes into a positive path of persistence and school completion. Despite ongoing efforts of the federal and state government, as well as those of the local school districts, this problem continues to burden the educational system and society as a whole. The opinions of those with the experience of dropping out and returning to school are pertinent sources of information on educative practices that can help stem the dropout rate.

A survey was conducted to gather the opinions of students …


Administrators' And Teachers' Perceptions Of In-School Suspension, Amelia Shondra Jackson Dec 2010

Administrators' And Teachers' Perceptions Of In-School Suspension, Amelia Shondra Jackson

Dissertations

Providing a safe and orderly school environment for students to learn is of paramount importance to school administrators, teachers, students, and the general public; however, the learning process should not be compromised while trying to maintain such an environment. There are many alternative approaches that can be utilized that would rectify the problem we as educators face in providing a safe and orderly environment. At-risk students are usually the ones who have the most serious infractions. These students exhibit a cyclical pattern of recalcitrant behavior. It is imperative that these at-risk students be identified as early as possible, and intervention …


Emotional Maturity Of Adolescents And Adults In Ged Programs, Billy Joe Riffle Dec 2010

Emotional Maturity Of Adolescents And Adults In Ged Programs, Billy Joe Riffle

Dissertations

When discussing issues relating to students in General Educational Development (GED) Option and pre-GED programs with educators, the contention exists that it is possible to make reasonably accurate predictions on the success or failure of a student by observing a number of items. Looking at their cumulative records shows their academic and attendance history. Insight is gained by looking at their family dynamics and how they relate to adults. Much can be learned about them from their discipline reports and the nature of any infractions. One of the most intriguing aspects gained through experience and observation is the perception of …


The Relationship Between Leader Decision Making And Student Achievement At K-3 Title I And Reading First Elementary Schools, Emily Kathleen Richmond Dec 2010

The Relationship Between Leader Decision Making And Student Achievement At K-3 Title I And Reading First Elementary Schools, Emily Kathleen Richmond

Dissertations

This mixed methodology study investigated the relationship between administrator and teacher perceptions of leader decision making regarding five variables (reading training, reading curriculum, program evaluation, financial support, and student assessment) and student achievement (in the single content area, reading, at the 3rd grade level) in Title I K-3 schools receiving Reading First Grants (RFGs) and Title I K-3 schools not receiving RFGs, in four states (Arkansas, Georgia, Idaho, and Oklahoma). Respondent data and district data regarding percentages of students achieving proficient and above on state third grade reading assessments were analyzed via Pearson Correlations, Multiple Regression Analysis, and a MANOVA. …


Life History And Habitat Use Of The Juvenile Alabama Shad (Alosa Alabamae) In Northern Gulf Of Mexico Rivers, Paul Fraser Mickle Dec 2010

Life History And Habitat Use Of The Juvenile Alabama Shad (Alosa Alabamae) In Northern Gulf Of Mexico Rivers, Paul Fraser Mickle

Dissertations

The Alabama shad, Alosa alabamae, is an anadromous species that is in decline and has seen extirpations from impoundments as well as decreased water quality. Alabama shad live in the Gulf of Mexico and ascend Northern Gulf of Mexico Drainages to reproduce early in the year (January-May). The juveniles spend the majority of the year in these freshwater systems before emigrating out to the Gulf of Mexico as late as December.

This dissertation focuses on the juvenile life stages that occur within the Northern Gulf of Mexico drainages. Spawning conditions of the river, as well as the habitat and diet, …


Stereo Matching Using A Modified Efficient Belief Propagation In A Level Set Framework, Stephen Goyer Rogers Dec 2010

Stereo Matching Using A Modified Efficient Belief Propagation In A Level Set Framework, Stephen Goyer Rogers

Dissertations

Stereo matching determines correspondence between pixels in two or more images of the same scene taken from different angles; this can be handled either locally or globally. The two most common global approaches are belief propagation (BP) and graph cuts.

Efficient belief propagation (EBP), which is the most widely used BP approach, uses a multi-scale message passing strategy, an O(k) smoothness cost algorithm, and a bipartite message passing strategy to speed up the convergence of the standard BP approach. As in standard belief propagation, every pixel sends messages to and receives messages from its four neighboring pixels in EBP. Each …


Folate Receptor-Targeted Delivery Of Small Interfering Rna To Cancer Cells, Yilin Zhang Dec 2010

Folate Receptor-Targeted Delivery Of Small Interfering Rna To Cancer Cells, Yilin Zhang

Dissertations

The vitamin folic acid (folate, FA) has been extensively explored as a targeting ligand to deliver a variety of diagnostic/prognostic/therapeutic agents into various tumors through the assistance of its receptor – the folate receptor (FR). FR is over-expressed in many types of human cancer and can mediate internalization of FA-conjugates through an endocytic pathway. The discovery of small interfering RNA (siRNA), which is cable of inducing potent gene silencing in a sequence-specific manner, provides an excellent molecular tool to suppress aberrant gene expression in malignancies, and therefore siRNA has the potential to revolutionize cancer therapeutics. Towards the goal of developing …


A Psychometric Investigation Of The Young Adult Social Behavior Scale (Yasb), Michelle Rene Augustin Dec 2010

A Psychometric Investigation Of The Young Adult Social Behavior Scale (Yasb), Michelle Rene Augustin

Dissertations

Aggressive behavior is a serious public health concern that has resulted in several problems in contemporary society. Despite a considerable body of literature on human aggression, both popular and scientific, a focus on overt physical aggression has obscured other forms of aggression. As a result, considerably less is known about other, more subtle forms of aggression, such as relational aggression. Moreover, research on relational aggression, particularly among older adolescents and adults, has been hindered by the lack of psychometrically sound measures. Research in this area would be enhanced by the availability of such a measure, facilitating comparison of data across …


Geological And Ichthyological Investigations Into Palaeodrainage Hypothesis For The Tennessee River, Andrea Karen Persons Dec 2010

Geological And Ichthyological Investigations Into Palaeodrainage Hypothesis For The Tennessee River, Andrea Karen Persons

Dissertations

The course of the ancestral Tennessee River has been debated in both the geological and biological literature for over 100 years. Several of the proposed courses for the ancestral Tennessee place its course across the state of Mississippi. Geochemical analysis of sedimentary rocks in the Pascagoula River basin supports these hypotheses suggesting that the rocks in the Pascagoula basin were derived from the Highland Rim of Tennessee and northern Alabama, while geochemical analysis of rocks from the Pearl River basin point to deposition from a mixture of sources including the ancestral Mississippi River and perhaps the ancestral Tennessee. To delve …


Older Adults And A Writing Workshop: A Phenomenological Study, Jennifer Lynn Alex Dec 2010

Older Adults And A Writing Workshop: A Phenomenological Study, Jennifer Lynn Alex

Dissertations

This study examines how older adults experience the phenomenon of participating in a writing workshop and how older adults interpret their experiences, understandings, and realities of writing. Ten older adults, ranging in age from 62 to 83 with varying degrees of experiences in writing, participated in this study. Through a semi-structured interview, each participant related his or her experience first as a writer and then as a member of a writing workshop offered through a Community Literacy Center in a mid-sized Appalachian city.

A phenomenological analysis method was used to identify and analyze themes of meaning that emerged in the …


The Effect Of A Math Emporium Course Redesign In Developmental And Introductory Mathematics Courses On Student Achievement And Students' Attitudes Toward Mathematics At A Two-Year College, Amy Renée Bishop Dec 2010

The Effect Of A Math Emporium Course Redesign In Developmental And Introductory Mathematics Courses On Student Achievement And Students' Attitudes Toward Mathematics At A Two-Year College, Amy Renée Bishop

Dissertations

The purpose of this research was to determine the effect of computer-based instruction on student mathematics achievement and students' attitudes toward mathematics in developmental and introductory mathematics courses, namely Elementary Algebra, Intermediate Algebra, and College Algebra, at a community college. The researcher also examined the relationship between attitudes and achievement. The sample consisted of 112 students, and the study was conducted during the Spring 2010 semester at a community college in south Mississippi. The participants were enrolled in one of six classes taught by the researcher. The control group consisted of three classes (one Intermediate and two College Algebra sections) …


Toxicogenomics Analysis Of Non-Model Transcriptomes Using Next-Generation Sequencing And Microarray, Arun Rawat Dec 2010

Toxicogenomics Analysis Of Non-Model Transcriptomes Using Next-Generation Sequencing And Microarray, Arun Rawat

Dissertations

With the advent of next generation technologies like Roche/454 Life Sciences that require low cost and less time for sequencing will help in providing a workable draft of non-model species genomes. Availability of high throughput microarray technologies for gene expression profiling provides low-cost tools for investigation of highly-integrated responses to various stimuli. These advancements along with bioinformatics processing have led to an increasing number of non-model species having well-annotated transcriptomes. The project focuses on the life cycle of development, functional annotation, and utilization of genomic tools for the avian wildlife species to determine the molecular impacts of exposure to munitions …


Synthesis And Electrical Properties Of Functional Block Copolymer/Inorganic Nanocomposite Materials, Hongying Chen Dec 2010

Synthesis And Electrical Properties Of Functional Block Copolymer/Inorganic Nanocomposite Materials, Hongying Chen

Dissertations

Sulfonated poly[styrene-b-ethylene-co-butylene-b-styrene] (sSEBS) block copolymers/inorganic nanocomposite materials were synthesized via in situ formation of inorganic fillers and characterized particularly for their dielectric properties and proton conductivities.

In preparation of sSEBS/SrTiO3 nanocomposites, titanium (IV) isopropoxide [Ti(OPri)4] complex was diffused into sSEBS film, followed by subsequent hydrolysis of [Ti(OPr i)4], diffusion of strontium cations in sSEBS domains, and in situ formation of crystalline SrTiO3. sSEBS with sulfonation degree of 38.1% and 65.0% were employed, and relevant sSEBS/SrTiO3 composites contain SrTiO3 of 10-15 wt%. Elemental composition characterization with ESEM/EDX indicated uniform distribution of …


Bemdec: An Adaptive And Robust Methodology For Digital Image Feature Extraction, Isaac Kueth Gang Dec 2010

Bemdec: An Adaptive And Robust Methodology For Digital Image Feature Extraction, Isaac Kueth Gang

Dissertations

The intriguing study of feature extraction, and edge detection in particular, has, as a result of the increased use of imagery, drawn even more attention not just from the field of computer science but also from a variety of scientific fields. However, various challenges surrounding the formulation of feature extraction operator, particularly of edges, which is capable of satisfying the necessary properties of low probability of error (i.e., failure of marking true edges), accuracy, and consistent response to a single edge, continue to persist. Moreover, it should be pointed out that most of the work in the area of feature …


Teacher Attitude Toward Differentiated Instruction In Third Grade Language Arts, Vivian Marina Mclean Dec 2010

Teacher Attitude Toward Differentiated Instruction In Third Grade Language Arts, Vivian Marina Mclean

Dissertations

The purpose of this study was to investigate teacher attitude toward differentiated instruction in third grade language arts in classrooms across a southern region of the United States. The researcher sought to answer four research questions “Does National Board Certification affect teacher attitude toward differentiated instruction,” “Does teacher education affect teacher attitude towards differentiated instruction?”, “Does teacher experience affect teacher attitude toward differentiated instruction?”, and “Does professional development affect teacher attitude toward differentiated instruction?”

The research findings supported the work of Tomlinson, McTighe, Webb, Wiggins, Vygotsky, and Gardner. Their literature served as a foundation in the identification of the variables …


The Relationship Among Mathematics Anxiety, Mathematical Self-Efficacy, Mathematical Teaching Self-Efficacy, And The Instructional Practices Of Elementary School Teachers, Lydia Joan Smith Dec 2010

The Relationship Among Mathematics Anxiety, Mathematical Self-Efficacy, Mathematical Teaching Self-Efficacy, And The Instructional Practices Of Elementary School Teachers, Lydia Joan Smith

Dissertations

The purpose of this quantitative, correlational study was to explore the relationships among the variables of mathematics anxiety, mathematical self-efficacy, mathematical teaching self-efficacy, and the instructional practice of elementary school teachers. The study included 320 practicing elementary teachers who teach mathematics to students in kindergarten through eighth grade. These teachers completed the Abbreviated Mathematics Anxiety Scale, the Mathematics Teaching and Mathematics Self-Efficacy survey, and the Patterns of Adaptive Learning Survey. Quantitative data analysis methods included descriptive statistics and multiple regression analysis. Results indicated a statistically significant relationship between mathematical teaching self-efficacy (efficacy) and mastery approaches to instruction, as well as …


Clinical Decision Making Of Rural Novice Nurses, Teresa J. Seright Dec 2010

Clinical Decision Making Of Rural Novice Nurses, Teresa J. Seright

Theses and Dissertations

The purpose of this study was to develop substantive theory regarding decision making by the novice nurse in a rural hospital setting. Interviews were guided by the following research questions: What cues were used by novice rural registered nurses in order to make clinical decisions? What were the sources of feedback which influenced subsequent decision making for processing of cues?

Theory development was based on an in-depth investigation of 12 novice nurses practicing in rural critical access hospitals in a North Central State. This study consisted of face to face interviews with 12 registered nurses, nine of whom were observed …


Acetate Causes Alcohol Hangover Headache In Rats., Christina R Maxwell, Rebecca Jay Spangenberg, Jan B Hoek, Stephen D Silberstein, Michael L Oshinsky Dec 2010

Acetate Causes Alcohol Hangover Headache In Rats., Christina R Maxwell, Rebecca Jay Spangenberg, Jan B Hoek, Stephen D Silberstein, Michael L Oshinsky

Department of Neurology Faculty Papers

BACKGROUND: The mechanism of veisalgia cephalgia or hangover headache is unknown. Despite a lack of mechanistic studies, there are a number of theories positing congeners, dehydration, or the ethanol metabolite acetaldehyde as causes of hangover headache.

METHODS: We used a chronic headache model to examine how pure ethanol produces increased sensitivity for nociceptive behaviors in normally hydrated rats.

RESULTS: Ethanol initially decreased sensitivity to mechanical stimuli on the face (analgesia), followed 4 to 6 hours later by inflammatory pain. Inhibiting alcohol dehydrogenase extended the analgesia whereas inhibiting aldehyde dehydrogenase decreased analgesia. Neither treatment had nociceptive effects. Direct administration of acetate …


Inclusive Dijet Cross Sections In Neutral Current Deep Inelastic Scattering At Hera, H. Abramowicz, I. Abt, L. Adamczyk, M. Adamus, R. Aggarwal, S. Antonelli, P. Antonioli, A. Antonov, M. Arneodo, V. Aushev, Y. Aushev, O. Bachynska, A. Bamberger, A. N. Barakbaev, G. Barbagli, G. Bari, F. Barreiro, D. Bartsch, M. Basile, O. Behnke, J. Behr, U. Behrens, L. Bellagamba, A. Bertolin, S. Bhadra, M. Bindi, C. Blohm, V. Bokhonov, T. Bołd, E. G. Boos, K. Borras, Margarita C. K. Mattingly Dec 2010

Inclusive Dijet Cross Sections In Neutral Current Deep Inelastic Scattering At Hera, H. Abramowicz, I. Abt, L. Adamczyk, M. Adamus, R. Aggarwal, S. Antonelli, P. Antonioli, A. Antonov, M. Arneodo, V. Aushev, Y. Aushev, O. Bachynska, A. Bamberger, A. N. Barakbaev, G. Barbagli, G. Bari, F. Barreiro, D. Bartsch, M. Basile, O. Behnke, J. Behr, U. Behrens, L. Bellagamba, A. Bertolin, S. Bhadra, M. Bindi, C. Blohm, V. Bokhonov, T. Bołd, E. G. Boos, K. Borras, Margarita C. K. Mattingly

Faculty Publications

Single- and double-differential inclusive dijet cross sections in neutral current deep inelastic ep scattering have been measured with the ZEUS detector using an integrated luminosity of 374 pb-1. The measurement was performed at large values of the photon virtuality, Q2, between 125 and 20 000 GeV2. The jets were reconstructed with the kT cluster algorithm in the Breit reference frame and selected by requiring their transverse energies in the Breit frame, ET,Bjet, to be larger than 8 GeV. In addition, the invariant mass of the dijet system, Mjj, was required to be greater than 20 GeV. The cross sections are …


An Annotated Bibliography Of Music Composed By Heinz Holliger For The Oboe, Oboe D'Amore, Or English Horn, Matthew Allen Ward Dec 2010

An Annotated Bibliography Of Music Composed By Heinz Holliger For The Oboe, Oboe D'Amore, Or English Horn, Matthew Allen Ward

Graduate Theses, Dissertations, and Problem Reports (ETD)

This annotated bibliography is intended to serve as a resource for those musicians seeking any compositions composed by Heinz Holliger for the oboe, oboe d'amore, or English horn for performance, pedagogical, or research-related purposes. This bibliography is a current listing of all published and unpublished compositions written for these instruments by Holliger as of March 2010. Twenty-four annotations provide information on performance-related criteria such as the year of completion, publisher, instrumentation, movements and titles, text and translation, available historical information, timing, difficulty, range, and extended techniques. Also included is a description and discussion of all the extended techniques that appear …


A Degradation Model For Solid Oxide Fuel Cell Anodes Due To Impurities In Coal Syngas, Fatma Nihan Cayan Dec 2010

A Degradation Model For Solid Oxide Fuel Cell Anodes Due To Impurities In Coal Syngas, Fatma Nihan Cayan

Graduate Theses, Dissertations, and Problem Reports (ETD)

Solid Oxide Fuel Cells (SOFCs) offer great promise as a clean and efficient alternative to conventional power generation technologies. A major advantage of SOFCs in comparison to other fuel cell types is that they can be operated directly on a wide variety of fuels including biogas, hydrocarbon fuels and coal-derived synthesis gas (syngas). SOFC operating on coal syngas is an especially attractive prospect given the abundant coal resources in the world. However, coal syngas usually contains various impurities such as phosphorus, arsenic, zinc, sulfur, mercury, selenium, and vanadium which affect the performance and durability of SOFCs. At low impurity concentrations, …


An Evaluation Of The Efficacy And Safety Of A Protocol To Premedicate Neonates For Elective Or Semi-Urgent Intubations In A Newborn Intensive Care Unit, Judith Dunmire Polak Dec 2010

An Evaluation Of The Efficacy And Safety Of A Protocol To Premedicate Neonates For Elective Or Semi-Urgent Intubations In A Newborn Intensive Care Unit, Judith Dunmire Polak

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background. Intubation is a painful and stressful procedure frequently performed in the NICU, yet less than 1% of US preterm infants receive premedication. The purpose of this study is to evaluate the efficacy of an intubation protocol in the NICU to add one 2mcg/kg dose of fentanyl prior to the procedure.;Objectives. The primary outcome was to decrease the time to successful intubation. Secondary outcomes were to increase staff knowledge regarding procedural pain, to reduce the number of attempts and to decrease adverse physiologic events.;Design. Staff attended one educational session. Pre- and post-tests assessed knowledge, beliefs, and attitudes. Data pre- and …


A Novel Global Pattern Recognition Algorithm, Joseph M. Stoffa Dec 2010

A Novel Global Pattern Recognition Algorithm, Joseph M. Stoffa

Graduate Theses, Dissertations, and Problem Reports (ETD)

The background, development, performance assessment, and analysis of a novel pattern recognition algorithm that is applicable to any set of binary images are discussed. The efficacy of the algorithm when applied to the problem of fingerprint recognition is quantified. The conclusion was that the algorithm is relatively poor as a fingerprint identification algorithm, averaging an equal error rate of approximately 19% as calculated by the rules specified in the Year 2000 Fingerprint Verification Competition. The positive attributes of the algorithm were its ultra-fast matching times, orientation independence, lack of rejection events, relative insensitivity to resolution difference, and one-way transformations. The …


4-H Fun With Foods - Lesson 3: Cookies: Drop & Bar, Georgia C. Lauritzen, Darlene Christensen, Susan Haws, Naomi Weeks, Debra Proctor, Ronda Olsen Dec 2010

4-H Fun With Foods - Lesson 3: Cookies: Drop & Bar, Georgia C. Lauritzen, Darlene Christensen, Susan Haws, Naomi Weeks, Debra Proctor, Ronda Olsen

All Current Publications

This publication is part of 4-H Fun with Foods Guide, Lesson 3 provides recipes and instructions to make drop and bar cookies.


Utah Fertilizer Guide, D. W. James, K. F. Topper Dec 2010

Utah Fertilizer Guide, D. W. James, K. F. Topper

All Current Publications

The Utah Fertilizer Guide is designed to provide practical answers to routine questions related to soil fertility management. The guide emphasizes laboratory analysis of soil and plant samples as the keystone to optimum fertilizer rates for maximum economic plant yield and quality. The focus of the guide is on soil fertility problems peculiar to the semi-arid and arid soils of Utah.


Structure And Expression Of Two Nuclear Receptor Genes In Marsupials: Insights Into The Evolution Of The Antisense Overlap Between The Α-Thyroid Hormone Receptor And Rev-Erbα, Brandon C. Rindfleisch, M. Scott Brown, John L. Vandeberg, Stephen Munroe Dec 2010

Structure And Expression Of Two Nuclear Receptor Genes In Marsupials: Insights Into The Evolution Of The Antisense Overlap Between The Α-Thyroid Hormone Receptor And Rev-Erbα, Brandon C. Rindfleisch, M. Scott Brown, John L. Vandeberg, Stephen Munroe

Biological Sciences Faculty Research and Publications

Background: Alternative processing of α-thyroid hormone receptor (TRα, NR1A1) mRNAs gives rise to two functionally antagonistic nuclear receptors: TRα1, the α-type receptor, and TRα2, a non-hormone binding variant that is found only in mammals. TRα2 shares an unusual antisense coding overlap with mRNA for Rev-erbα (NR1D1), another nuclear receptor protein. In this study we examine the structure and expression of these genes in the gray short-tailed opossum, Monodelphis domestica, in comparison with that of eutherian mammals and three other marsupial species, Didelphis virginiana, Potorous tridactylus and Macropus eugenii, in order to understand the evolution and regulatory …