Digital Commons Network^™

"If We Shadows Have Offended": Reflections Of Social Attitudes Toward Reform In Late Medieval And Reformation Dream Visions, William A. Racicot

Electronic Theses and Dissertations

14th-century dream visions feature intensely personal narrators with attitudes and desires, who agonize over difficult situations, who make errors in judgment. Deeply characterized narrators contribute thematically to these poems, which explore personal subjects like grief and faith. By the 16th century, the form had undergone a thematic transformation from personal narrative to political allegory, losing much of its potency. The narrators use the dream vision structure in order to beg authority figures to forgive the potentially offensive statements made in their work because it was only a dream. Many narrators are ciphers, the eyes and mouthpieces of a theme rather …

Roots: Agrarian Movements And The Importance Of Ground Within The Philosophy Of Communication (A Synecdoche), Maryl Roberts Mcginley

Electronic Theses and Dissertations

This work looks at the way in which an agrarian philosophy communicates the meaningful connection between cultivating land and being attentive to the philosophical notion of ground. It tells the story of agrarian movements from the last century with special attention to what about the philosophy has durability. This work outlines the possibility of an agrarian framework as a potential alternative to modernity. Each chapter is attentive to a different voice in the movement, exploring his engagement with an agrarian philosophy and connection to the philosophy of communication.

Effect Of Melatonin On Differentiation Of Human Mesenchymal Stem Cells And A Study On C-Terminal Domains Of Mt1 And Mt2 Melatonin Receptors, Shalini Sethi

Electronic Theses and Dissertations

Melatonin has been reported to enhance the differentiation of osteoblasts. The purpose of this study was to determine the melatonin treatment that would differentiate human mesenchymal stem cells (hAMSCs) into osteoblasts. A 21 d continuous melatonin treatment significantly increased the alkaline phosphatase (ALP) activity and the deposition of calcium in hAMSCs. These effects were inhibited by MT2 specific antagonist- 4P-PDOT. The time periods of melatonin treatment that increased the expression of osteogenic genes indicated both a sensitized and desensitized receptors with respect to cAMP signaling, signifying two distinct mechanisms of melatonin's action. Unlike the parathyroid hormone which is administered in …

Exploration Of Trpv1 Splice Variant Expression In Rat Dorsal Root Ganglia Following Sciatic Nerve Injury, Karl A. Andersen

Electronic Theses and Dissertations

Transient Receptor Potential Vanilloid 1 (TRPV1) is ligand-gated ion channel that plays an important role in the pain signaling pathway. It is predominantly expressed by sensory neurons located in trigeminal ganglia or dorsal root ganglia (DRG). TRPV1 has been shown to play a crucial role in the generation and maintenance of inflammatory and neuropathic pain. The involvement of splice variants of TRPV1 in pain pathways is not well known. In this study, the mRNA expression of TRPV1 and 3 splice variants (TRPV1.b, TRPV1.β, and TRPV1.var) in DRG was measured following chronic constriction injury of the sciatic nerve in rats. This …

Nicomachean And Neo-Aristotelian Ethics And Shakespeare's Tragedies, Janine Bayer

Electronic Theses and Dissertations

"Nicomachean and Neo-Aristotelian Ethics in Shakespeare's Tragedies" examines two of Shakespeare's most compelling tragedies--Othello and King Lear--through the lens of contemporary virtue ethics theory, thereby offering new conceptions of how morality operates in these plays. Although neo-Aristotelian moral philosophers locate the roots of their theories in Aristotle's Nicomachean Ethics, their arguments reach far beyond Aristotle's original theoretical conception, offering innovative ways for us to understand virtue in our analysis of morality. The dissertation Introduction provides an overview of contemporary moral philosophy--i.e., the state of normative ethics today, including brief explanations of Deontology, Teleology, and Virtue theory. Discussion in Chapter One …

Department Of Education: Fy10 Annual Report, Lehigh Valley Health Network

Department of Education

No abstract provided.

Synthesis Of Bicyclic Pyrrolo[2,3-D]Pyrimidines, And Tricyclic Indeno[2,1-D]/[1,2-D]Pyrimidines As Receptor Tyrosine Kinase (Rtk) Inhibitors And Antimitotic Agents, Ying Zhao

Electronic Theses and Dissertations

The dissertation will give an introduction, background and our research progress in the areas of receptor tyrosine kinases inhibitors and antimitosis inhibitors. The design and syntheses of bicyclic pyrrolo[2,3-d]pyrimidines, and tricyclic indeno[2,1-d]- and [1,2-d]pyrimidines as receptor tyrosine kinase inhibitors and bicyclic pyrrolo[2,3-d]pyrimidines, and tricyclic indeno[2,1-d]pyrimidines as antimitotic inhibitors have been described. As a part of this study, a total of two hundred and eleven new compounds have been synthesized and characterized. Of these, ninety five final compounds were submitted for biological evaluation.

A Role For Lipid Rafts In Egfr Tki Resistance In Breast Cancer, Mary Elizabeth Irwin

Wayne State University Dissertations

Breast cancer can be divided into genetic sub-types including luminal, HER2+, and basal-type. With the introduction of targeted therapies against estrogen receptor and HER2 receptor mortality rates of American women with breast cancer have declined. Unfortunately, basal-type breast cancers, which have the worst clinical outcome, do not express estrogen receptor or HER2, and as such, have no targeted therapeutic option. The epidermal growth factor receptor is an attractive target for therapeutics in basal-type breast cancer, as it is over-expressed in 60% of these cases. Also, over-expression of EGFR correlates with poor patient prognosis. Unfortunately, inhibitors of EGFR have shown little …

The Guarantee Clause In The States: Structural Protections For Minority Rights And Necessary Limits On The Initiative Power, Anya J. Stein

UC Law Constitutional Quarterly

This Note discusses the constitutional significance of the Guarantee Clause of Article IV, Section 4, which states that "[t]he United States shall guarantee to every State in this Union, a Republican Form of Government." For decades, the United States Supreme Court has held that the Guarantee Clause presents a nonjusticiable political question in the federal courts. Notwithstanding this federal doctrine, the Guarantee Clause remains justiciable in the state courts.

State ballot initiatives are vulnerable to uses that violate the Guarantee Clause's protection of the republican form of government. This Note presents a three-part argument. First, the Guarantee Clause provides critical …

Tax Reform Commissioners In The Sweep Of California's Fiscal History, Steven M. Shefrin

UC Law Constitutional Quarterly

What role do tax reform commissions play in California fiscal history? The recent California Commission on the 21st Century Economy-the Parsky Commission-temporarily raised hopes for substantive tax reform in California. However, its apparent failure raises broader questions about the role of tax commissions. Have they ever led to fundamental tax policy changes in the state and, if so, what made them successful?

To address these questions, this paper explores the experiences of two important California tax commissions, the 1906 and 1929 commissions, and places them into the history of taxation in California. Both the recommendations of the 1906 and 1929 …

Between Safety And Transparency: Prior Restraints, Foia, And The Power Of The Executive, Devin S. Schindler

UC Law Constitutional Quarterly

The Freedom of Information Act, and, to a lesser extent, the Constitution, embody a democratic commitment to transparent and open government. Roughly balanced against this commitment is the need in selected circumstances to prevent the release of information that could lead directly or indirectly to tangible harm to America and its interests. Most recently, the debate between safety and transparency came to the forefront in the case American Civil Liberties Union v Department of Defense, where the Second Circuit ordered the President to release a series of nonconfidential but potentially inflammatory pictures showing prisoner abuse at the Abu Ghraib prison. …

Seeking Common Ground: A Secular Statement, Bruce Ledewitz

UC Law Constitutional Quarterly

It is clear that there is a crisis today in the interpretation of the Establishment Clause. Not only do we not know what the Clause means, we do not even have clear opposing constitutional visions. At the same time, we have today a related crisis in American political life between religious believers and nonbelievers over the proper place of religion in politics. Finally, we have today in the West, a crisis of social morals as older religious certainties fade and secularism drifts dangerously close to nihilism. In my view, all of these issues are related. The answer to all three …

The Marketplace Metaphor And Commercial Speech Doctrine: Or How I Learned To Stop Worrying About And Love Citizens United, Darrel C. Menthe

UC Law Constitutional Quarterly

In this article, I place the Citizens United decision in historical and doctrinal context, and argue that the decision indicates a terminal stage of the development and application of the "marketplace of ideas" metaphor in First Amendment law. I argue that the "good news" about the Citizens United decision is that it sets the stage for the abolition of the commercial speech doctrine, which resulted in lower protection for commercial speech, as previously set forth in the 1980 Central Hudson decision. This is good news because the commercial speech doctrine has become a doctrinal anomaly that threatens to undermine the …

Regulation Of Vcam-1 Expression By Tgfβ2 During The Formation Of The Epicardium, Margaret Elizabeth Grant Burton

MUSC Theses and Dissertations

The normal formation of the epicardium, the outer cell layer of the heart, is critical for subsequent development of the heart to proceed normally. Abnormalities in the epicardium lead to cardiac defects as shown in mice deficient in retinoid X receptor α (RXRα-/-), a model of congenital heart disease that exhibits many cardiac malformations including epicardial defects. The RXRα-/- epicardium is slower to form and once formed, it detaches from the myocardium. Previously an elevation of transforming growth factor β2 (TGFβ2) has been observed in RXRα-/- hearts at midgestation and an alteration in vascular cell adhesion molecule 1 (VCAM-1) was …

Accessing Children's Perspectives Through Participatory Photo Interviews, Jane Jorgenson, Tracy Sullivan

Communication Faculty Publications

In this article we seek to contribute to the emerging conversation on child-centered research methods by reflecting on the use of participatory photo interviewing to understand children's experiences with household technology. Participatory photo interviews attempt to engage children as active research participants by giving them cameras and inviting them to take pictures dealing with various aspects of their lives. The photos are later used in the interview process to jointly explore the subjective meaning of the images. We focus here on how children oriented to the research task, and in particular, on the ethnographic insights obtained by attending to the …

Soil- And Groundwater-Quality Data For An Abandoned Cattle And Hog Feedlot In Henderson County, Kentucky, E. Glynn Beck, James S. Dinger, Eugenia Pena-Yewtukhiw, John H. Grove

Information Circular--KGS

Groundwater samples collected from a livestock well in southwestern Henderson County, Ky., contained nitrate-N concentrations greater than 20 mg/L, two times the U.S. Environmental Protection Agency’s maximum contaminant level. The well is located in an abandoned cattle and hog feedlot. The feedlot is located in an upland bedrock setting with Pleistocene loess overlying Pennsylvanian bedrock. One hundred twenty-one soil cores were collected to better define the areal extent of organic-rich soil believed to be the source of the elevated nitrate-N in the groundwater. Cores were collected on 25-ft centers to a depth of 4 ft below the land surface. Soil …

Sources And Occurrences Of Nonpoint-Source Chemicals In Groundwater, Jackson Purchase Region, Kentucky, R. Stephen Fisher, E. Glynn Beck

Report of Investigations--KGS

Nitrate concentrations that exceed U.S. Environmental Protection Agency drinking-water standards have been reported in Jackson Purchase Region groundwater since the 1960's. More recently, other nonpoint-source chemicals such as pesticides and volatile organic compounds have also been found. The sources of these chemicals and the pathways by which they reach domestic groundwater supplies must be determined to protect human health and to design effective land-management practices.

To investigate the occurrence of nonpoint-source chemicals in Jackson Purchase groundwater, 60 wells were selected on the basis of geographic location, hydrostratigraphic unit penetrated, and well type (bored or drilled); distances to row crops, known …

Entering Into The Profound Mystery: Yves Congar’S Via Media On The Salvation Of People Of Non-Christian Religions, Elizabeth M. Cunneen

School of Theology and Seminary Graduate Papers/Theses

The twenty-first century Catholic Church is in the process of understanding its relation to the Second Vatican Council. Yves Congar, one of the most influential theologians at the council, had a theological career spanning over fifty years, and his theological insights remain pertinent to contemporary historical and cultural concerns. This paper describes Yves Congar’s particular ecclesiological, pneumatological and Christological insights in response to the question of the salvation of people of non-Christian religions. Congar seeks to find a via media, or middle way, which denies two extreme perspectives, one of which holds that explicit non-Christians are not saved, and …

Natural History Of Blue-And-Yellow Macaws (Ara Ararauna) In Miami-Dade County, Florida, Bill Pranty, Daria Feinstein, Karen Lee

Florida Field Naturalist

No abstract provided.

Use Of Supplemental Northern Bobwhite (Colinus Virginianus) Food By Non-Target Species, Gail Morris, L. Mike Conner, Madan K. Oli

Florida Field Naturalist

No abstract provided.

Design Strategies For Mitigating Passenger Door Holding Behavior On Suburban Trains In Paris, Selby Coxon, Karen Burns, Arthur De Bono

World Transit Research

The length of time a train is halted at a station is particularly important during service peak periods and short headways. Some passenger behaviors, such as the deliberate holding open of doors, has a detrimental effect upon maintaining short dwell times and service timetable. Mechanical malfunction due to door holding is also a significant contributor to trains having to be removed from service.
There is a general absence of literature in the transportation field examining this problem or offering potential solutions. This paper discusses a commissioned research project carried out by Monash University’s Department of Design for the French National …

Blue Carbon: The Role Of Healthy Oceans In Binding Carbon, Christian Nellemann, Emily Corcoran, Carlos M. Duarte, Cassandra De Young, Luciano E. Fonseca, Gabriel Grimsdith

Center for Coastal and Ocean Mapping

No abstract provided.

An Evaluation Of Habitat Models For The Common Loon (Gavia Immer), Alexis M. Rudko

Master's Theses and Capstones

The Loon Preservation Committee (LPC) has been collecting field data for the common loon (Gavia immer) in New Hampshire for thirty-six years. A habitat model for lakes throughout New Hampshire was created by Dr. Mark Brennan for the time period 1980--2002. This project re-evaluates Brennan's habitat model using new data from 2003--2008. Two additional models, one with all lakes and another with the three largest lakes excluded, were created and compared to Brennan's model to see if the overall accuracy improved. These models show which lakes have high and low potential for loon habitat. The results of the re-evaluation of …

Western Maine Saints: The First Mormons Of Western Maine 1830--1890, Carole A. York

Master's Theses and Capstones

This thesis is about the forty-nine individuals and ten families who converted to the Church of Jesus Christ of Latter-day Saints (LDS) in Bethel and Newry, Maine and the missionaries who brought them into the church. The account includes a brief history of these small back country towns, providing the historical context for the early church in Maine, and continues with the experiences of these Saints as they fled from persecution in Ohio, Missouri, and Illinois. In February, 1846, the Mormons began the arduous trek to the Great Salt Lake Basin. This thesis shows that these converts, typical of other …

Increasing Written Language Skills Utilizing Writing Software And Traditional Methods, Caroline Larson

Undergraduate Honors Theses

A grid based computer program, Clicker5, appeared to have many features that logically may assist struggling writers. It utilizes pictures, sound, speech synthesis, word banks and a spelling checker. Karemaker et al. (2008) examined the use of Clicker5 and observed increased attention and focus during reading, and greater gains in word recognition and rhyme awareness. Scattered research exists on some of the multimedia features that Clicker5 utilizes (e.g. auditory and visual instruction, specific feedback, student specific examples, Wissick & Gardner, 2000; composition processes and revision facilitation, MacArthur 2000; spell checkers with strategy instruction, and speech synthesis to increase error …

How Our Health Depends On Biodiversity, Eric Chivian M.D., Aaron Bernstein M.D., M.P.H.

Ecosystem Disruption & Climate Change

The eminent Harvard biology Professor Edward O.Wilson once said about ants, “We need them to survive, but they don’t need us at all.” The same, in fact, could be said about countless other insects, bacteria, fungi, plankton, plants, and other organisms. This fundamental truth, however, is largely lost to many of us. Rather, we humans often act as if we are totally independent of Nature, as if our driving thousands of other species to extinction and disrupting the life-giving services they provide will have no effect on us whatsoever.

This summary, using concrete examples from our award-winning Oxford University Press …

Jewish Heritage Sites And Monuments In Moldova, Samuel D. Gruber

Religion - All Scholarship

2010 report from the United States Commission for the Preservation of America's Heritage Abroad on historic Jewish sites in Romania. Includes information on the history and current conditions of synagogues, cemeteries, and holocaust memorials.

Historic Jewish Sites In Romania, Samuel D. Gruber

Religion - All Scholarship

2010 report from the United States Commission for the Preservation of America's Heritage Abroad on historic Jewish sites in Romania. Includes information on the history and current conditions of synagogues, cemeteries, and holocaust memorials.

Intercultural Communications: Medicine Across Cultures, Danielle Tomeck

Intertext

No abstract provided.

Save As... Knowledge And Transmission In The Age Of Digital Technologies, Diana Taylor

Imagining America

Diana Taylor, university professor and professor of Performance Studies and Spanish, New York University, provides a rich entry point into complex questions about digital media and its implications for scholarly practice. Drawing on her experience with the Hemispheric Institute of Performance and Politics, a multinational collaboration of artists and scholars grounded in an on-line archive of performance work across the Americas, Taylor insists that we need to imagine communities that are not only local or national and publics that are not exclusive to the present. Attending to the ways in which digital innovations inflect earlier technologies for creating and transmitting …