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Hyperpolarized Xenon-129 Magnetic Resonance Imaging Of Functional Lung Microstructure, Isabel Dregely

Doctoral Dissertations

Hyperpolarized 129Xe (HXe) is a non-invasive contrast agent for lung magnetic resonance imaging (MRI), which upon inhalation follows the functional pathway of oxygen in the lung by dissolving into lung tissue structures and entering the blood stream. HXe MRI therefore provides unique opportunities for functional lung imaging of gas exchange which occurs from alveolar air spaces across the air-blood boundary into parenchymal tissue. However challenges in acquisition speed and signal-to-noise ratio have limited the development of a HXe imaging biomarker to diagnose lung disease.

This thesis addresses these challenges by introducing parallel imaging to HXe MRI. Parallel imaging requires dedicated …

Updated Life History And Population Structure Assessment Of Spiny Dogfish, Squalus Acanthias, In The Gulf Of Maine, Walter Bubley

Doctoral Dissertations

Spiny dogfish (Squalus acanthias) are considered to be the most abundant shark species in the Western North Atlantic, but recently there was a decline in biomass estimates following a nearly ten-fold increase in fishery landings. Because fishing pressure has been shown to affect population dynamics in targeted species, an update of previous life history parameters is warranted to effectively manage the population. Although updated and accurate life history parameters are important, it is crucial that these parameters are applied to the correct populations, especially when there is evidence of population structuring in the Western Atlantic. This comprehensive study addressed the …

The Long Journey To Become 'The River Of National Unity': The Sao Francisco River Basin From 1940s To 2008 And The Interactions Of Environment, Government And Local Citizens, Lucigleide Nery Nascimento

Doctoral Dissertations

In its 2,700 kilometers north and then eastern journey to the Atlantic Ocean, the Sao Francisco River of Brazil drains eight percent of the nation's territory. The watershed is three and a half times the size of New England. This research investigates the impacts of the federal water resource management, or lack of it, on the riverine environment and on the life of the people who locally have depended on the ecosystem's services of the river during the 1940s--2008 timeframe. A new legal instrument, the 1997 Water Policy, introduced a novel form of management regarding public participation, policy goals and …

The Effects Of Didemnum Vexillum Overgrowth On Mytilus Edulis Biology And Ecology, Linda Ann Auker

Doctoral Dissertations

Didemnum vexillum is an invasive colonial ascidian in the Gulf of Maine that readily colonizes hard substrates. These substrates include hard-shelled organisms, such as the common blue mussel Mytilus edulis. Preliminary observations and short-term studies showed potential effects of epibiosis on M. edulis growth, specifically lip thickness and tissue index. This dissertation study further examined the effects of D. vexillum on growth and reproduction of, and predation on, M. edulis. Shell thickness index, tissue index, shell mass to tissue mass ratio, lip thickness and mussel length were measured throughout a 12-month period in control and overgrown mussels. Additionally, histological preparations …

Movement And Behavior Of Ocean Sunfish, Mola Mola, In The Northwest Atlantic, Inga F. Potter

Doctoral Dissertations

The ocean sunfish, Mola mola, has a worldwide distribution and is a common resident of the NW Atlantic Ocean. Notable for its unusual anatomy and large size, the biology of the species is largely unknown. I examined the movement and behavior of M. mola using pop-up satellite archival tags (PSAT's). In addition, analysis of aerial survey data was conducted to determine the distribution of ocean sunfish (Family Molidae) in NW Atlantic shelf waters. Data was analyzed from twenty-five PSAT's deployed on M. mola in the northwest Atlantic between 2005 and 2008. Tags were attached from 7-242 days. Results indicate that …

Spatial Management Of Groundfish Resources In The Gulf Of Maine And Georges Bank, Jamie Marie Cournane

Doctoral Dissertations

In the marine environment, studies suggest that overfishing suppresses sustainability and resilience in fish populations. In the 1990s, the National Marine Fisheries Service (NMFS) implemented five large year-round fishery closures in the Gulf of Maine and Georges Bank. These closures are partially protected marine protected areas (MPAs) restricting commercial fishing with bottom-tending gears. To date, evaluation of their performance has focused on the productivity of individual species.

This research aims to understand if fish biodiversity changed after implementation of the five large fisheries closures. Here, a variety of datasets and statistical approaches are used.

Modern patterns constructed from NMFS bottom-trawl …

Factors Regulating The Production Of Stx-2 In Escherichia Coli O157:H7, Kate P. Stefani

Doctoral Dissertations

The severity of Escherichia coli O157:H7 disease is due in part to a major virulence factor produced by the microbe, the shiga-like toxin 2 (Stx-2). Antibiotic treatment to reduce pathogen numbers is controversial, as it is thought that antibiotics may increase the levels of Stx-2 released from the pathogen. Currently, recommended treatment for E. coli O157:H7 is palliative The purpose of this study was to examine three critical factors potentially important to disease outcomes, and to determine their effect on expression of the stx2 gene and on release of Stx-2 from the pathogen. Those factors selected for study were: (i) …

Comprehension Of Protagonists' Goals And Intentions: The Dynamic Relation Between Reading Skill, Text Characteristics, And Reading Strategies, Jennifer J. Stiegler

Doctoral Dissertations

Studies by the National Assessment of Educational Progress (NAEP, 2009) indicate that the inability to comprehend text is one of the primary reasons students perform poorly in school Reading difficulties often persist into adulthood with 23% of U.S. adults only meeting basic reading proficiency levels (NCES, 2004). To address this problem, it is critical to identify the underlying cognitive processes that pose the greatest challenges to struggling readers. Recent research has explored basic skills (e.g., working memory capacity, suppression mechanisms, domain knowledge, and reading strategies) that have been shown to be essential for reading. To date it is unclear which …

From Biosphere To Noosphere: Vladimir Vernadsky's Theoretical System As A Conceptual Framework For Universal Sustainability Education, Irina L. Trubetskova

Doctoral Dissertations

In light of accelerating global warming and climate change, the importance of sustainability education is unquestionable. It is a requirement of our time that sustainability education must become a part of any professional curriculum in higher education because today's college students are tomorrow's decision makers and the key players at local, national, and international levels.

Although the importance of education for a sustainable future has been recognized by the global community and we are now living through the United Nations Decade of Education for Sustainable Development (2005-2014), a common conceptual approach to teaching sustainability does not exist. We face a …

"This Wilderness World": The Evolution Of A New England Farm Town, 1820--1840, Mary Babson Fuhrer

Doctoral Dissertations

This dissertation uses the extraordinary conflict that roiled one rural town in central Massachusetts during the second quarter of the nineteenth century as a lens through which to observe communal relationships in transition. Using the Amish as a model, the dissertation identifies traditional communal social organization as agrarian, patriarchal, communal, homogeneous, localistic, and consensual -- as well as closed, conformist, and suspicious of difference and innovation. The dissertation argues that conflict arose in Boylston during the 1820s and '30s as these traditional relationships gradually gave way to more modern ways of belonging, associating, and envisioning one's place in the wider …

Land Development In Massachusetts: Its Effect On The Environment Within Essex And Middlesex Counties From 1990 To 2007, Peter Sean Tardie

Doctoral Dissertations

Since the 1970's urban centers in and surrounding Essex and Middlesex Counties in Massachusetts have expanded and proliferated into adjacent communities. This expansion has led to the conversion of land for housing, businesses, schools, recreation, and parks, placing significant strain on existing land cover, land use, and available natural resources. Mounting growth pressures and a reduction of undeveloped land have raised serious concerns as cropland and forest fragmentation, wetland destruction, protected open-space infringement, pollution, and systematic losses of rural conditions have become obvious. To monitor development, the post-classification change detection method was applied to Landsat Thematic Mapper (TM) satellite data …

The Voice Fiction Edition, Connecticut College

2009-2010

No abstract provided.

Toward A Pro-Life Environmental Movement, Lucia A. Silecchia

Scholarly Articles

In modern times, the secular environmental movement seems to have taken on an anti-life message, in ways both subtle and direct. This anti-human – and often anti-life – view has crept into the heart of the “mainstream” ecological movement with consequences that can be detrimental to both human dignity and to the environment itself. This essay does not aim to analyze the complexities inherent in economic development, demographic predictions, or climatology. Instead, it is a call to reflect carefully and soberly on the troubling moral consequences of grounding respect for the environment in disrespect for the dignity of the human …

Sexual Signal Evolution Outpaces Ecological Divergence During Electric Fish Species Radiation, Matthew E. Arnegard, Peter B. Mcintyre, Luke J. Harmon, Miriam L. Zelditch, William G. R. Crampton, Justin K. Davis, John P. Sullivan, Sébastien Lavoué, Carl D. Hopkins

Faculty Bibliography 2010s

Natural selection arising from resource competition and environmental heterogeneity can drive adaptive radiation. Ecological opportunity facilitates this process, resulting in rapid divergence of ecological traits in many celebrated radiations. In other cases, sexual selection is thought to fuel divergence in mating signals ahead of ecological divergence. Comparing divergence rates between naturally and sexually selected traits can offer insights into processes underlying species radiations, but to date such comparisons have been largely qualitative. Here, we quantitatively compare divergence rates for four traits in African mormyrid fishes, which use an electrical communication system with few extrinsic constraints on divergence. We demonstrate rapid …

Systematic Identification Of Conserved Motif Modules In The Human Genome, Xiaohui Cai, Lin Hou, Naifang Su, Haiyan Hu, Minghua Deng, Xiaoman Li

Faculty Bibliography 2010s

Background: The identification of motif modules, groups of multiple motifs frequently occurring in DNA sequences, is one of the most important tasks necessary for annotating the human genome. Current approaches to identifying motif modules are often restricted to searches within promoter regions or rely on multiple genome alignments. However, the promoter regions only account for a limited number of locations where transcription factor binding sites can occur, and multiple genome alignments often cannot align binding sites with their true counterparts because of the short and degenerative nature of these transcription factor binding sites. Results: To identify motif modules systematically, we …

Angiogenesis: An Update And Potential Drug Approaches, Maen Abdelrahim, Santhi Konduri, Riyaz Basha, Philip A. Philip, Cheryl H. Baker

Faculty Bibliography 2010s

The therapeutic potential of targeting tumor endothelium and vascular supply is now widely recognized to treat different diseases. One such disease is cancer; where endothelial cells are actively proliferating to support the tumor growth. Solid tumors cannot grow beyond the size of a few millimeters without inducing the proliferation of endothelium and formation of new blood vessels. Hence it is crucial to search for new agents that selectively block tumor blood supply. These include anti-angiogenic molecules, vascular disrupting agents or endothelial disrupting agents. The anti-angiogenic molecules such as monoclonal antibodies and tyrosine kinase inhibitors disrupt endothelial cell survival mechanisms and …

Taking The Good With The Bad: Recognizing The Negative Externalities Created By Charities And Their Implications For The Charitable Deduction, Shannon Weeks Mccormack

Articles

The tax code allows taxpayers to deduct amounts donated to an extremely broad variety of organizations deemed to create societal benefits — that is, positive externalities. But many organizations that may receive tax-deductible contributions also cause harms. Both the tax code and subsidy theory, one of the most utilized scholarly theories developed to analyze the deduction from an economic and morally neutral perspective, fail to properly account for these negative externalities. In order to do so, one needs to look beyond the economic models utilized by subsidy theorists. For instance, there should be some limit to the types of harms …

Referential Choices In Narratives Of 4-Year-Old Thai-Speaking Children, Theeraporn Ratitamkul

Manusya, Journal of Humanities

This paper examines how 4-year-old Thai-speaking children made referential choices when referring to animate entities in a story. The aim is to answer two questions. First, do young Thai children's narratives exhibit Preferred Argument Structure (PAS) patterns (Du Bois 1987)? And, second, do young Thai children differentiate their choice of referential forms based on discourse contexts? It was found that children's selection of referential forms generally followed the PAS constraints. The only constraint that was not strictly observed was the Non-lexical A constraint. Furthermore, children were found to be influenced by discourse contexts when they expressed arguments in subject positions. …

Children’S Fiction Discourse Analysis: The Critique Of Victorian Economics In George Macdonald’S The Princess And Curdie, Osama Jarrar

North Wind: A Journal of George MacDonald Studies

No abstract provided.

The Other Side Of The Story: Using Graphic Organizers To Counter The Counter-Analysis Quandary, Lisa T. Mcelroy, Christine N. Coughlin

University of Baltimore Law Review

No abstract provided.

Que Ondee Sola - January-Feb 2010, Xavier Luis Burgo

Que Ondee Sola

Student publication founded in 1972, articles include: Poetry

Western Australian Resource Condition Monitoring Projects 2007-2009, Ceidwen Pengelly, 2010

All other publications

Monitoring the status and trends of our natural resources is the only way we can assess whether the actions that have been implemented are making a difference. The impetus for this resource condition monitoring program (RCM) was the recognition that our monitoring networks, baseline data and data management systems were inadequate to enable quantitative reporting to government, and the community, on the difference their investments in natural resource management were making. It was considered that making a significant investment in raising our ability to report would be a long-lasting legacy of value to the state.

The Representation Of Place In Middlemarch, Adam Wright

The George Eliot Review Online, ISSN: 2831-5375

Critics in the past have tended to refer to the rootedness of characters in George Eliot's novels. This is particularly true of Adam Bede, where the naturalistic roots of characters are often explicitly stated, such as when Dinah affirms 'I'm not free to leave Snowfield, where I was first planted, and have grown deep into it, like the small grass on the hill-top'.1 Catherine Middleton, in her essay 'Roots and Rootlessness', when analysing Middlemarch refers to seven different types of roots in just four pages (,emotional', 'physical', 'moral', 'affective', 'social', 'intellectual' ,and 'local').2 These terms not only complicate our understanding …

'Good Teaching': Adam Bede And Education, Dinah Birch

The George Eliot Review Online, ISSN: 2831-5375

George Eliot's commitment to teaching motivates her writing from the first. Like many of those whose thinking was shaped by early nineteenth-century evangelicalism, she saw education as a vital responsibility. In 1847, when she was twenty-eight years old, she remarked to Sara Hennell that she thought '''Live and Teach" should be a proverb as well as "Live and Learn"'.1 Eliot's persistent interest in teaching and learning was a reason for her turning to fiction as her primary medium as a writer - not the only reason, but an important one. She had no inclination whatsoever to become a professional teacher, …

Expressive Things In Adam Bede, Barabar Hardy

The George Eliot Review Online, ISSN: 2831-5375

A drop of ink is the first thing in the first sentence of George Eliot's first novel: 'With a single drop of ink for a mirror, the Egyptian sorcerer undertakes to reveal to any chance corner farreaching visions of the past.' Like many objects in Adam Bede, this one is more complicated than first appears. In its generalized imaging of magical creation, ritual and prophesy, it is an invocation, introducing and solemnizing the other object with which it is twinned and compared, the real drop of ink at the end of the author's pen which has actually written this sorcerer's …

Superior Domesticity: Two George Eliot Cats, Beryl Gray

The George Eliot Review Online, ISSN: 2831-5375

The Persian cat, Hafiz, appears in two scenes in Daniel Deronda (1876) .1 The first of these appearances occurs in chapter 18, which introduces the compact, creative little Meyrick women - mother and three daughters - just as they are about to become Mirah Lapidoth's hospitable benefactresses, though she is as yet unknown to them. They are gathered harmoniously together in the evening lamp- and candle-lit, miniature double parlour of their narrow riverside house. 'All four, if they had been wax-work, might have been packed easily in a fashionable lady's travelling trunk.'2 Their corporeal diminutiveness is …

Studies In Cyberspace: Honors, Professional Teacher Development, Curricular Development, And Systemic Change In Louisiana, Brian C. Etheridge, Galen Turner, Heath Tims, Christian A. Duncan

Honors in Practice Online Archive

For years, honors programs and colleges have experienced well-documented difficulties in justifying and defending their budgets (and in some cases their existence). These challenges—some of which are discussed in the 2006 JNCHC “Forum on Honors Administration” and the 2009 JNCHC “Forum on Social Class and Honors”—have ranged from the philosophical (“honors programs are elitist”) to the pragmatic (“we have to take care of our own students first, so we can’t spare any faculty for an honors class”). Honors administrators have therefore developed an extensive and effective litany of benefits that emphasize how honors programs enhance the student experience, the health …

Recent Editions, Margaret A. Hogan

Documentary Editing: Journal of the Association for Documentary Editing (1979–2011)

This annual bibliography of documentary editions recently published in the fields of American and British history, literature, and culture is generally restricted to scholarly first editions of English-language works. In addition to the bibliographical references, Internet addresses are provided for the editorial project or the publisher.

Auswertung Der In Den Jahren 1993-2009 Im Östlichen Altai (Russland) Und Südöstlichen Altai (Tyva) Gesammelten Federn Und Rupfungen, W.-D. Busching

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

Determination-results of birds from Russian Altai-Mountains and Tyva based on plucked and moult-feathers.

This paper deals with plucked- and moult-feathers of different Central-Asian birds collected by STEPHAN ERNST, DANIEL MICHELE LINDNER and JENS HERING in the Russian Altai- Mountains and Tyva 1993 - 2009.

Beobachtungen Zu Unterscheidungsmerkmalen An Equidenschädeln, Speziell Zwischen Denen Von Mongolischen Dschiggetai Und Pferden, Roland Müller, Joachim Wussow

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

First paragraph:

Von STUBBE et.al. wurden zwischen 2001 und 2004 in der Südmongolei ca. 400 Schädel des Dschiggetai (Equus hemionus hemionus) gesammelt.