Digital Commons Network^™

The Sagebrush Steppe Treatment Evaluation Project (Sagestep): A Test Of State-And Transition Theory., J. D. Mciver, Mark W. Brunson, S. Buntin, J. Chambers, N. Devoe, P. Doescher, J. Grace, D. Johnson, S. Knick, R. Miller

Environment and Society Faculty Publications

No abstract provided.

Hegelian Priorities In Christendom: A Reconsideration, Howard P. Kainz

Philosophy Faculty Research and Publications

Arguments from the nineteenth century concerning whether Hegel was an atheist or a theist are still ongoing. This paper examines Hegel’s philosophical and theological milieu, his influence on the history of philosophy and on politics, his unique interpretation of the unity of theology and philosophy, and his unusually sanguine interpretation of the relationship between church and state, along with special problems he discerned in the emergence of democracies.

Symbol And Function In Contemporary Architecture For Museums, Curtis Carter

Philosophy Faculty Research and Publications

No abstract provided.

Fifth Grade Student Learning And Interest In The American Revolution Through Reading Graphic Novels Compared To Reading Biography Or Other Nonfiction Books, Kari Bosma

Graduate Research Papers

The purpose of this study was to examine student recall of facts, along with enjoyment of reading and interest in the topic when using graphic novels as compared to illustrated nonfiction prose in social studies content area reading. Twenty-two fifth grade students (13 f, 9 m) in a public school in a Midwestern state participated in the study. Half of the students read about the Boston Massacre and Patrick Henry through graphic novels and read about Paul Revere and the Boston Tea Party with illustrated nonfiction texts, with the other half doing the opposite. The mean number of correct ideas …

Transgenic Rat Model Of Neurodegeneration Caused By Mutation In The Tdp Gene, Hongxia Zhou, Cao Huang, Han Chen, Dian Wang, Carlisle P. Landel, Pedro Yuxing Xia, Robert Bowser, Yong-Jian Liu, Xu Gang Xia

Nebraska Center for Biotechnology: Faculty and Staff Publications

TDP-43 proteinopathies have been observed in a wide range of neurodegenerative diseases. Mutations in the gene encoding TDP-43 (i.e., TDP) have been identified in amyotrophic lateral sclerosis (ALS) and in frontotemporal lobe degeneration associated with motor neuron disease. To study the consequences of TDP mutation in an intact system, we created transgenic rats expressing normal human TDP or a mutant form of human TDP with a M337V substitution. Overexpression of mutant, but not normal, TDP caused widespread neurodegeneration that predominantly affected the motor system. TDP mutation reproduced ALS phenotypes in transgenic rats, as seen by progressive degeneration of motor neurons …

Cytocompatible Cross-Linking Of Electrospun Zein Fibers For The Development Of Water-Stable Tissue Engineering Scaffolds, Quiran Jiang, Narendra Reddy, Yiqi Yang

Department of Agricultural and Biological Systems Engineering: Faculty Publications

This paper reports a new method of cross-linking electrospun zein fibers using citric acid as a non-toxic cross-linker to enhance the water stability and cytocompatibility of zein fibers for tissue engineering and other medical applications. The electrospun structure has many advantages over other types of structures and protein-based biomaterials possess unique properties preferred for tissue engineering and other medical applications. However, ultrafine fiber matrices developed from proteins have poor mechanical properties and morphological stability in the aqueous environments required for medical applications. Efforts have been made to improve the water stability of electrospun protein scaffolds using cross-linking and other approaches, …

Microwave-Based Alkali Pretreatment Of Switchgrass And Coastal Bermudagrass For Bioethanol Production, Deepak R. Keshwani, Jay J. Cheng

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Switchgrass and coastal bermudagrass are promising lignocellulosic feedstocks for bioethanol production. However, pretreatment of lignocelluloses is required to improve production of fermentable sugars from enzymatic hydrolysis. Microwave-based alkali pretreatment of switchgrass and coastal bermudagrass was investigated in this study. Pretreatments were carried out by immersing the biomass in dilute alkali reagents and exposing the slurry to microwave radiation at 250 W for residence times ranging from 5 to 20 minutes. Simons’ stain method was used to quantify changes in biomass porosity as a result of the pretreatment. Pretreatments were evaluated based on yields of total reducing sugars, glucose, and xylose. …

Improving The Value Of Standard Toxicity Test Data In Reach, Magnus Breitholtz, Elin Lundström, Ulrika Dahl, Valery E. Forbes

Valery Forbes Publications

Worldwide, environmental risk assessment strategies are based on the assumption that measuring direct effects of single substances, using a few single species tests, in combination with safety factors correcting for extrapolation inconsistencies, can be used to protect higher levels of biological organization, such as populations and even ecosystems. At the same time, we are currently facing a range of pollution problems (Millennium Ecosystem Assessment Series 2005), of which some could at least indirectly be linked to the fact that this assumption may not be fully valid. Consequently, there is an ongoing scientific debate on whether current chemical control protocols are …

Candida Albicans Cellwall Components And Farnesol Stimulate The Expression Of Both Inflammatory And Regulatory Cytokines In The Murine Raw264.7 Macrophage Cell Line, Suman Ghosh, Nina Howe, Katie Volk, Swetha Tati, Kenneth W. Nickerson, Thomas M. Petro

Kenneth Nickerson Papers

Candida albicans causes candidiasis, secretes farnesol, and switches from yeast to hyphae to escape from macrophages after phagocytosis. However, before escape, macrophages may respond to C. albicans’ pathogen-associated molecular patterns (PAMPs) through toll-like receptor 2 (TLR2) and dectin-1 receptors by expressing cytokines involved in adaptive immunity, inflammation, and immune regulation. Therefore, macrophages and the RAW264.7 macrophage line were challenged with C. albicans preparations of live wild-type cells, heat-killed cells, a live mutant defective in hyphae formation, a live mutant producing less farnesol, or an isolate producing farnesoic acid instead of farnesol. Interleukin-6 (IL-6), and IL-1b, IL- 10, and tumor …

Molecular Basis Of A Novel Adaptation To Hypoxic-Hypercapnia In A Strictly Fossorial Mole, Kevin L. Campbell, Jay F. Storz, Anthony V. Signore, Hideaki Moriyama, Kenneth C. Catania, Alexander P. Payson, Joseph Bonaventura, Jörg Stetefeld, Roy E. Weber

Jay F. Storz Publications

Background: Elevated blood O₂ affinity enhances survival at low O₂ pressures, and is perhaps the best known and most broadly accepted evolutionary adjustment of terrestrial vertebrates to environmental hypoxia. This phenotype arises by increasing the intrinsic O₂ affinity of the hemoglobin (Hb) molecule, by decreasing the intracellular concentration of allosteric effectors (e.g., 2,3-diphosphoglycerate; DPG), or by suppressing the sensitivity of Hb to these physiological cofactors.

Results: Here we report that strictly fossorial eastern moles (Scalopus aquaticus) have evolved a low O₂ affinity, DPG-insensitive Hb - contrary to expectations for a mammalian species that is …

Review Of The Rhetoric Of Intellectual Property: Copyright Law And The Regulation Of Digital Culture, By Jessica Reyman, Jessica Silbey

Faculty Scholarship

A short book review of Jessica Reyman’s, The Rhetoric of Intellectual Property: Copyright Law and the Regulation of Digital Culture.

Study Of The Egfr, Src And Stat3 Pathway In Pancreatic Cancer, Soumya Jaganathan

Electronic Theses and Dissertations

Cancer is associated with many molecular aberrations that support the malignant phenotype. In that regard, aberrant activation of epidermal growth factor receptor (EGFR), Src, and signal transducer and activator of transcription 3 (Stat3) occur concurrently in pancreatic cancer and are implicated in the disease phenotype. Notwithstanding, increasing evidence indicates that therapies that target only EGFR or Src are rather ineffective in modulating the cancer phenotype. The poor therapeutic outcome of the monotherapies targeting EGFR or Src may in part be due to the increased incidence of signaling cross-talks among aberrant signaling pathways in cancer. Molecular details of the signaling integration …

Dryland Soil Carbon And Nitrogen Influenced By Sheep Grazing In The Wheat–Fallow System, Upendra M. Sainju, Andrew W. Lenssen, Hayes B. Goosey, Erin Snyder, Patrick G. Hatfield

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Sheep (Ovis aries) grazing during fallow for weed control in wheat (Triticum aestivum L.)–fallow systems may influence soil C and N levels and grain yields by returning part of consumed crop residue to the soil through feces and urine. We evaluated the effects of fallow management (sheep grazing [grazing], herbicide application [chemical], and tillage [mechanical]) for weed control and soil water conservation and cropping sequence (continuous spring wheat [CSW], spring wheat–fallow [SW-F], and winter wheat–fallow [WW-F]) on soil organic carbon (SOC), inorganic carbon (SIC), total nitrogen (STN), NH₄–N, and NO₃–N levels at the 0- to …

Permanent Genetic Resources Added To The Molecular Ecology Resources Database 1 February 2010–31 March 2010, D. Aurelle, M. R. Pooler, T. A. Rinehart, B. E. Scheffler, Molecular Ecology Resources Primer Development Consortium

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

This article documents the addition of 228 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Anser cygnoides, Apodemus flavicollis, Athene noctua, Cercis canadensis, Glis glis, Gubernatrix cristata, Haliotis tuberculata, Helianthus maximiliani, Laricobius nigrinus, Laricobius rubidus, Neoheligmonella granjoni, Nephrops norvegicus, Oenanthe javanica, Paramuricea clavata, Pyrrhura orcesi and Samanea saman. These loci were cross-tested on the following species: Apodemus sylvaticus, Laricobius laticollis and Laricobius osakensis (a proposed new species currently being described).

Is Ashcroft V. Iqbal The Death (Finally) Of The “Historical Test” For Interpreting The Seventh Amendment?, Kenneth S. Klein

Faculty Scholarship

There is the possibility that the recent Supreme Court decision of Ashcroft v. Iqbal finally will be the necessary impetus to revisit one of the more bizarre but enduring canards of American jurisprudence -- the way we interpret the Seventh Amendment's preservation of a right to a jury trial in federal civil litigation. The Seventh Amendment provides that "[i]n suits at common law ... the right of trial by jury shall be preserved." To this day, the way we apply the Seventh Amendment-in other words, what we interpret to be the constitutional intent and mandate of our Founders-is to postulate …

Chronic Inflammatory Responses To Microgel-Based Implant Coatings, Amanda W. Bridges, Rachel E. Whitmire, Neetu Singh, Kellie L. Templeman, Julia E. Babensee, L. Andrew Lyon, Andrés J. García

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Inflammatory responses to implanted biomedical devices elicit a foreign body fibrotic reaction that limits device integration and performance in various biomedical applications. We examined chronic inflammatory responses to microgel conformal coatings consisting of thin films of poly(N-isopropylacrylamide) hydrogel microparticles cross-linked with poly(ethylene glycol) diacrylate deposited on poly(ethylene terephthalate) (PET). Unmodified and microgel-coated PET disks were implanted subcutaneously in rats for 4 weeks and explants were analyzed by histology and immunohistochemistry. Microgel coatings reduced chronic inflammation and resulted in a more mature/organized fibrous capsule. Microgel-coated samples exhibited 22% thinner fibrous capsules that contained 40% fewer cells compared to unmodified PET disks. …

Describing The Phenomena Of Principals' Experiences With Implementation Of Response To Intervention, Lorrie Belk Butler

Electronic Theses and Dissertations

The traditional method of identifying students with disabilities has led to a new innovation being implemented at the school level. Response to Intervention (RTI) is an alternative approach that received federal approval with the passage of Individuals with Disabilities Educational Improvement Act (IDEIA) 2004. On July 1, 2010, RTI became the required process for determining identification of students with learning disabilities for all schools in the state of Florida. Implementation of this approach requires significant changes in how schools operate. Using a phenomenological study design, the purpose of this study was to gain an understanding of the experiences of elementary …

The "Just War" Theory: Application To United States And Israeli Militarism, Daniel C. Maguire

Theology Faculty Research and Publications

No abstract provided.

Whom The Gods Would Destroy, They First Make Myopic: Religion And Ethics In Cross-Disciplinary Ecological Dialogue, Daniel C. Maguire

Theology Faculty Research and Publications

No abstract provided.

Scripture In The Pastoral Letters Of The Provincial Councils Of Baltimore, Eric Vanden Eykel

Theology Faculty Research and Publications

In the pastoral letters of the provincial councils of Baltimore (1829-1849), a dramatic shift occurs in the way Scripture is employed as a source of authority; in the earlier letters, the role of Scripture is commanding and evident, while in the later, it is almost invisible. This article addresses each letter in turn, outlining the ways in which Scripture is employed to illustrate and reinforce the decrees of the provincial councils. The analysis suggests that Scripture's role in the 1829-1840 letters corresponds to the turbulent environment of the Catholic Church in America, especially in relation to Protestant nativist groups, and …

Identification Of Novel Antimalarials From Marine Natural Products For Lead Discovery, Stephenie M. Alvarado

Electronic Theses and Dissertations

An estimated 500 million cases of malaria occur each year. The increasing prevalence of drug resistant strains of Plasmodium in most malaria endemic areas has significantly reduced the efficacy of current antimalarial drugs for prophylaxis and treatment of this disease. Therefore, discovery of new, inexpensive, and effective drugs are urgently needed to combat this disease. Marine biodiversity is an enormous source of novel chemical entities and has been barely investigated for antimalarial drug discovery. In an effort to discover novel therapeutics for malaria, we studied the antimalarial activities of a unique marine-derived peak fraction library provided by Harbor Branch Oceanographic …

Concentric Layout, A New Scientific Data Layout For Matrix Data Set In Hadoop File System, Lu Cheng

Electronic Theses and Dissertations

The data generated by scientific simulation, sensor, monitor or optical telescope has increased with dramatic speed. In order to analyze the raw data speed and space efficiently, data preprocess operation is needed to achieve better performance in data analysis phase. Current research shows an increasing tread of adopting MapReduce framework for large scale data processing. However, the data access patterns which generally applied to scientific data set are not supported by current MapReduce framework directly. The gap between the requirement from analytics application and the property of MapReduce framework motivates us to provide support for these data access patterns in …

Designing Of Energy Efficient Indoor Environments Using A Localized Radial Basis Function Meshless Method, Victor Huayamave

Electronic Theses and Dissertations

Around the world, the energy over consumption issue has been one of the key socio-economic and political challenges, which has drastically worsened over the last few years. Over the years engineers and environmentalists have proposed several approaches to improve energy efficiency. One is to reduce energy demand by improving consumption habits and a second approach is to introduce the use of a "greener" concept by using biomaterials in a diverse and more efficient manner in engineering construction to create energy efficient environments. This work will investigate the effects of using "green" stabilized earth materials to provide and enhance thermal regulation …

Grade 7 Native Americans, Bryan Fierson

Social Studies

This lesson on Native American life will be a three-day lesson that includes, among other differentiated elements, a hook sparking the students' imagination through fantasy, a direct instruction session, two anchor activities, a group reading activity, a creative writing exercise, and performance tasks to measure student comprehension and learning.

Ordinary Creativity In Patent Law: The Artist Within The Scientist, Amy L. Landers

Missouri Law Review

Patent law is intended to promote the creativity of scientists and engineers. The system recognizes that the work of the individual is the engine that ultimately increases the state ofscientific knowledge. As economist Paul Romer recognized, "Technological advance comes from things that people do." Furthering creativity represents the constitutional, theoretical and doctrinal heart of patent law. Yet the field has not meaningfully evaluated the fundamental question of what creativity is. Using theories from psychology, sociology, history and the philosophy of science, this work examines and proposes how patent law can formulate a legal conception of creativity. To undertake this inquiry, …

The Heath Anthology Of American Literature - Sixth Edition, Volume C: Late Nineteenth Century: 1865-1910, Paul Lauter, John Alberti, Mary Pat Brady, Jackson R. Bryer, King-Kok Cheung, Kirk Curnutt, Anne Goodwyn Jones, Richard Yarborough, James Kyung-Jin Lee, Wendy Martin, Quentin Miller

Covers, Titles, and Tables: The Formations of American Literary Canons in Anthologies - Archive

Contains Title Page, Table of Contents

Guardians Of Municipal Public Trees: Commonwealth Of Massachusetts Tree Wardens’ Authority And Accountability, Julie E. Steiner

Western New England Law Review

Today’s tree wardens are continually called upon to strike a balance between preservation of public trees and protection of the public from hazardous tree conditions. The Commonwealth of Massachusetts has been a pioneer in tree protection legislation, including the enactment of the first state legislation requiring a municipal tree warden. As guardians of the municipal landscape, tree wardens decide whether and when to plant new public shade trees, or to permit those that already exist to be cut, trimmed, or removed. This Article describes the important historical role the Commonwealth of Massachusetts has played in protecting public trees, the legal …

Effect Of Ingestion By Alligator Snapping Turtles (Macrochelys Temminckii) On Seeds Of Riparian Vegetation, Jean Pierre Elbers

Graduate Theses/Dissertations

The alligator snapping turtle (Macrochelys temminckii) is a large freshwater turtle that inhabits many lotic water bodies in the Southeastern United States. The species consumes primarily fish but also consumes large amounts of vegetation including seeds of common persimmon (Diospyros virginiana), tupelos (Nyssa sp.), willow oak (Quercus phellos), and pecan (Carya illinoensis). Captive specimens of M. temminckii were fed samples of the above-mentioned seeds to assess how the species affects ingested seeds in order to evaluate the potential role this species may play as a seed disperser. The proportion of seeds defecated intact varied with species (57−99 %), was lowest …

Clean, Green, And Not So Mean: Can Business Save The World?, Andy Spackman, Celia Ross, Christy Donaldson, Louise Feldman, Patrick Griffis, Elizabeth Stephan, Laurie Bridges, Baseema Krkoska, Tony Lin, Mark Siciliano

Library Faculty Research

No matter how you define it, corporate social responsibility (CSR) is a hot topic. From community investing to business ethics to environmental sustainability and beyond, proponents of CSR view the business landscape through a lens that focuses less on profitability and more on the greater good.

“Doing well by doing good” is the business world’s new mantra. Concepts of CSR, green business, social entrepreneurship, and peace through commerce have become a focus of research and are inspiring the next generation of businesspeople. The 2010 BRASS Program gave attendees an expert’s view of certain niches within the broader realm of ethical …

Emerging Law Addressing Climate Change And Water, Elizabeth Burleson

Elisabeth Haub School of Law Faculty Publications

The World Economic Forum recognizes that while restrictions on energy affect water systems and vise versa, energy and water policy are rarely coordinated. The International Panel on Climate Change predicts that wet places will become wetter and dry places will become dryer. Transboundary water, energy and climate coordination can occur through international consensus building.