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2009

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The Shrunken Power Of The Purse, Alan L. Feld Jan 2009

The Shrunken Power Of The Purse, Alan L. Feld

Faculty Scholarship

The Constitution places control of the federal government's funds in the hands of Congress. This article examines Congress' exercise of discretion in connection with expenditures, impoundments, debt and taxation. It concludes that its actual control over the government's funds has become limited over time and makes recommendations for more robust exercise of its traditional authority.


Induction Of Ifn-Beta And The Innate Antiviral Response In Myeloid Cells Occurs Through An Ips-1-Dependent Signal That Does Not Require Irf-3 And Irf-7, Stephane Daffis, Mehul S. Suthar, Kristy J. Szretter, Michael Gale Jr., Michael S. Diamond Jan 2009

Induction Of Ifn-Beta And The Innate Antiviral Response In Myeloid Cells Occurs Through An Ips-1-Dependent Signal That Does Not Require Irf-3 And Irf-7, Stephane Daffis, Mehul S. Suthar, Kristy J. Szretter, Michael Gale Jr., Michael S. Diamond

Open Access Publications

No abstract provided.


Chronic Cyclodextrin Treatment Of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol And Glycosphingolipid Storage And Disease Progression, Cristin D. Davidson, Nafeeza F. Ali, Mathew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie T. Vanier, Steven U. Walkley Jan 2009

Chronic Cyclodextrin Treatment Of Murine Niemann-Pick C Disease Ameliorates Neuronal Cholesterol And Glycosphingolipid Storage And Disease Progression, Cristin D. Davidson, Nafeeza F. Ali, Mathew C. Micsenyi, Gloria Stephney, Sophie Renault, Kostantin Dobrenis, Daniel S. Ory, Marie T. Vanier, Steven U. Walkley

Open Access Publications

No abstract provided.


The Effects Of Tail Biopsy For Genotyping On Behavioral Responses To Nociceptive Stimuli, Maria Elena P. Morales, Robert W. Gereau Iv Jan 2009

The Effects Of Tail Biopsy For Genotyping On Behavioral Responses To Nociceptive Stimuli, Maria Elena P. Morales, Robert W. Gereau Iv

Open Access Publications

No abstract provided.


G Protein Subunit Dissociation And Translocation Regulate Cellular Response To Receptor Stimulation, Mariangela Chisari, Deepak Kumar Saini, Joon-Ho Cho, Vani Kalyanaraman, N. Gautam Jan 2009

G Protein Subunit Dissociation And Translocation Regulate Cellular Response To Receptor Stimulation, Mariangela Chisari, Deepak Kumar Saini, Joon-Ho Cho, Vani Kalyanaraman, N. Gautam

Open Access Publications

No abstract provided.


Dosage Effects Of Cohesin Regulatory Factor Pds5 On Mammalian Development: Implications For Cohesinopathies, Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Kulkarni Shashikant, Matthew A. Deardorff, Maria L. Giovannucci Uzielli, Dale Dorsett, David C. Beebe, Patrick Y. Jay, Robert O. Heuckeroth, Ian Krantz, Jeffrey Milbrandt Jan 2009

Dosage Effects Of Cohesin Regulatory Factor Pds5 On Mammalian Development: Implications For Cohesinopathies, Bin Zhang, Jufang Chang, Ming Fu, Jie Huang, Rakesh Kashyap, Ezequiel Salavaggione, Sanjay Jain, Kulkarni Shashikant, Matthew A. Deardorff, Maria L. Giovannucci Uzielli, Dale Dorsett, David C. Beebe, Patrick Y. Jay, Robert O. Heuckeroth, Ian Krantz, Jeffrey Milbrandt

Open Access Publications

No abstract provided.


Functional Brain Networks Develop From A ‘‘Local To Distributed’’ Organization, Damian A. Fair, Alexander L. Cohen, Jonathan D. Power, Nico U. F. Dosenbach, Jessica A. Church, Fancis M. Miezin, Bradley L. Schlaggar, Steven E. Petersen Jan 2009

Functional Brain Networks Develop From A ‘‘Local To Distributed’’ Organization, Damian A. Fair, Alexander L. Cohen, Jonathan D. Power, Nico U. F. Dosenbach, Jessica A. Church, Fancis M. Miezin, Bradley L. Schlaggar, Steven E. Petersen

Open Access Publications

No abstract provided.


Helminth Genomics: The Implications For Human Health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman Jan 2009

Helminth Genomics: The Implications For Human Health, Paul J. Brindley, Makedonka Mitreva, Elodie Ghedin, Sara Lustigman

Open Access Publications

No abstract provided.


Degradation Of Host Sphingomyelin Is Essential For Leishmania Virulence, Ou Zhang, Mattie C. Wilson, Wei Xu, Fong-Fu Hsu, John Turk, F. Matthew Kuhlmann, Yingwei Wang, Lynn Soong, Phillip Key, Stephen M. Beverley, Kai Zhang Jan 2009

Degradation Of Host Sphingomyelin Is Essential For Leishmania Virulence, Ou Zhang, Mattie C. Wilson, Wei Xu, Fong-Fu Hsu, John Turk, F. Matthew Kuhlmann, Yingwei Wang, Lynn Soong, Phillip Key, Stephen M. Beverley, Kai Zhang

Open Access Publications

No abstract provided.


Between Community And Hospital: Healthcare-Associated Gram-Negative Bacteremia Among Hospitalized Patients, Jonas Marschall, Victoria J. Fraser, Joshua Doherty, David K. Warren Jan 2009

Between Community And Hospital: Healthcare-Associated Gram-Negative Bacteremia Among Hospitalized Patients, Jonas Marschall, Victoria J. Fraser, Joshua Doherty, David K. Warren

Open Access Publications

No abstract provided.


Developing A Risk Stratification Model For Surgical Site Infection After Abdominal Hysterectomy, Margaret A. Olsen, James Higham-Kessler, Deborah S. Yokoe, Anne M. Butler, Johanna Vostok, Kurt B. Stevenson, Yosef Khan, Victoria J. Fraser Jan 2009

Developing A Risk Stratification Model For Surgical Site Infection After Abdominal Hysterectomy, Margaret A. Olsen, James Higham-Kessler, Deborah S. Yokoe, Anne M. Butler, Johanna Vostok, Kurt B. Stevenson, Yosef Khan, Victoria J. Fraser

Open Access Publications

No abstract provided.


Difficulty In Diagnosing Surgical Site Infection After Arthroscopy In Developing Countries, Anucha Apisarnthanarak, Siriporn Wittayachanyapong, Pranee Sitaposa, Kanokporn Thongphubeth, Hilary Babcock, Victoria J. Fraser Jan 2009

Difficulty In Diagnosing Surgical Site Infection After Arthroscopy In Developing Countries, Anucha Apisarnthanarak, Siriporn Wittayachanyapong, Pranee Sitaposa, Kanokporn Thongphubeth, Hilary Babcock, Victoria J. Fraser

Open Access Publications

No abstract provided.


Multicenter Study Of The Impact Of Community-Onset Clostridium Difficile Infection On Surveillance For C. Difficile Infection, Erik R. Dubberke, Anne M. Butler, Bala Hota, Yosef M. Khan, Julie E. Mangino, Jeanmarie Mayer, Kyle J. Popovich, Kurt B. Stevenson, Deborah S. Yokoe, L Clifford Mcdonald, John Jernigan, Victoria J. Fraser Jan 2009

Multicenter Study Of The Impact Of Community-Onset Clostridium Difficile Infection On Surveillance For C. Difficile Infection, Erik R. Dubberke, Anne M. Butler, Bala Hota, Yosef M. Khan, Julie E. Mangino, Jeanmarie Mayer, Kyle J. Popovich, Kurt B. Stevenson, Deborah S. Yokoe, L Clifford Mcdonald, John Jernigan, Victoria J. Fraser

Open Access Publications

No abstract provided.


Cost-Effectiveness Analysis Of A Silver-Coated Endotracheal Tube To Reduce The Incidence Of Ventilator-Associated Pneumonia, Andrew F. Shorr, Marya D. Zilberberg, Marin Kollef Jan 2009

Cost-Effectiveness Analysis Of A Silver-Coated Endotracheal Tube To Reduce The Incidence Of Ventilator-Associated Pneumonia, Andrew F. Shorr, Marya D. Zilberberg, Marin Kollef

Open Access Publications

No abstract provided.


Impact Of An Antimicrobial Utilization Program On Antimicrobial Use At A Large Teaching Hospital: A Randomized Controlled Trial, Bernard C. Camins, Mark D. King, Jane B. Wells, Heidi L. Googe, Manish Patel, Ekaterina V. Kourbatova, Henry M. Blumberg Jan 2009

Impact Of An Antimicrobial Utilization Program On Antimicrobial Use At A Large Teaching Hospital: A Randomized Controlled Trial, Bernard C. Camins, Mark D. King, Jane B. Wells, Heidi L. Googe, Manish Patel, Ekaterina V. Kourbatova, Henry M. Blumberg

Open Access Publications

No abstract provided.


Selection At A Single Locus Leads To Widespread Expansion Of Toxoplasma Gondii Lineages That Are Virulent In Mice, Asis Khan, Sonya Taylor, James W. Ajioka, Benjamin M. Rosenthal, L. David Sibley Jan 2009

Selection At A Single Locus Leads To Widespread Expansion Of Toxoplasma Gondii Lineages That Are Virulent In Mice, Asis Khan, Sonya Taylor, James W. Ajioka, Benjamin M. Rosenthal, L. David Sibley

Open Access Publications

No abstract provided.


Supplementing High-Density Snp Microarrays For Additional Coverage Of Disease-Related Genes: Addiction As A Paradigm, Scott F. Saccone, Laura J. Bierut, Elissa J. Chesler, Peter W. Kalivas, Caryn Lerman, Nancy L. Saccone, George R. Uhl, Chuan-Yun Li, Vivek M. Philip, Howard J. Edenberg, Stephen T. Sherry, Michael Feolo, Robert K. Moyzis, Joni L. Rutter Jan 2009

Supplementing High-Density Snp Microarrays For Additional Coverage Of Disease-Related Genes: Addiction As A Paradigm, Scott F. Saccone, Laura J. Bierut, Elissa J. Chesler, Peter W. Kalivas, Caryn Lerman, Nancy L. Saccone, George R. Uhl, Chuan-Yun Li, Vivek M. Philip, Howard J. Edenberg, Stephen T. Sherry, Michael Feolo, Robert K. Moyzis, Joni L. Rutter

Open Access Publications

No abstract provided.


Bioinformatics Methods For Learning Radiation-Induced Lung Inflammation From Heterogeneous Retrospective And Prospective Data, Sarah J. Spencer, Damian Almiron Bonnin, Joseph O. Deasy, Jeffrey D. Bradley, Issam El Naqa Jan 2009

Bioinformatics Methods For Learning Radiation-Induced Lung Inflammation From Heterogeneous Retrospective And Prospective Data, Sarah J. Spencer, Damian Almiron Bonnin, Joseph O. Deasy, Jeffrey D. Bradley, Issam El Naqa

Open Access Publications

No abstract provided.


Vav Links The T Cell Antigen Receptor To The Actin Cytoskeleton And T Cell Activation Independently Of Intrinsic Guanine Nucleotide Exchange Activity, Ana V. Miletic, Daniel B. Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J. Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D. Billadeau, Osami Kanagawa, Makio Tokunaga, Wojciech Swat Jan 2009

Vav Links The T Cell Antigen Receptor To The Actin Cytoskeleton And T Cell Activation Independently Of Intrinsic Guanine Nucleotide Exchange Activity, Ana V. Miletic, Daniel B. Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J. Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D. Billadeau, Osami Kanagawa, Makio Tokunaga, Wojciech Swat

Open Access Publications

No abstract provided.


The Physical And Genetic Framework Of The Maize B73 Genome, Fusheng Wei, Jianwei Zhang, Shiguo Zhou, Ruifeng He, Mary Schaeffer, Kristi Collura, David Kudrna, Ben P. Faga, Marina Wissotski, Wolfgang Gloser, Susan M. Rock, Tina A. Graves, Robert S. Fulton, Ed Coe, Patrick S. Schnable, David C. Schwartz, Doreen Ware, Sandra W. Clifton, Richard K. Wilson, Rod A. Wing Jan 2009

The Physical And Genetic Framework Of The Maize B73 Genome, Fusheng Wei, Jianwei Zhang, Shiguo Zhou, Ruifeng He, Mary Schaeffer, Kristi Collura, David Kudrna, Ben P. Faga, Marina Wissotski, Wolfgang Gloser, Susan M. Rock, Tina A. Graves, Robert S. Fulton, Ed Coe, Patrick S. Schnable, David C. Schwartz, Doreen Ware, Sandra W. Clifton, Richard K. Wilson, Rod A. Wing

Open Access Publications

No abstract provided.


A Role Of Scn9a In Human Epilepsies, As A Cause Of Febrile Seizures And As A Potential Modifier Of Dravet Syndrome, Nanda A. Singh, Chris Pappas, E. Jill Dahle, Lieve R. F. Claes, Timothy H. Pruess, Peter De Jonghe, Joel Thompson, Missy Dixon, Christina Gurnett, Andy Peiffer, H. Steve White, Francis Filloux, Mark F. Leppert Jan 2009

A Role Of Scn9a In Human Epilepsies, As A Cause Of Febrile Seizures And As A Potential Modifier Of Dravet Syndrome, Nanda A. Singh, Chris Pappas, E. Jill Dahle, Lieve R. F. Claes, Timothy H. Pruess, Peter De Jonghe, Joel Thompson, Missy Dixon, Christina Gurnett, Andy Peiffer, H. Steve White, Francis Filloux, Mark F. Leppert

Open Access Publications

No abstract provided.


In Vitro Growth Environment Produces Lipidomic And Electron Transport Chain Abnormalities In Mitochondria From Nontumorigenic Astrocytes And Brain Tumours, Michael A. Kiebish, Xianlin Han, Hua Cheng, Thomas N. Seyfried Jan 2009

In Vitro Growth Environment Produces Lipidomic And Electron Transport Chain Abnormalities In Mitochondria From Nontumorigenic Astrocytes And Brain Tumours, Michael A. Kiebish, Xianlin Han, Hua Cheng, Thomas N. Seyfried

Open Access Publications

No abstract provided.


Item Response Modeling Of Dsm-Iv Mania Symptoms In Two Representative Us Epidemiological Samples, A. Agrawal, J. I. Nurnberger Jr., M. T. Lynskey Jan 2009

Item Response Modeling Of Dsm-Iv Mania Symptoms In Two Representative Us Epidemiological Samples, A. Agrawal, J. I. Nurnberger Jr., M. T. Lynskey

Open Access Publications

No abstract provided.


Bringing Kash Under The Sun: The Many Faces Of Nucleo-Cytoskeletal Connections, David Razafsky, Didier Hodzic Jan 2009

Bringing Kash Under The Sun: The Many Faces Of Nucleo-Cytoskeletal Connections, David Razafsky, Didier Hodzic

Open Access Publications

No abstract provided.


Physical Activity And Colon Cancer Prevention: A Meta-Analysis, Kathleen Yaus Wolin, Yan Yan, Graham A. Colditz, I. M. Lee Jan 2009

Physical Activity And Colon Cancer Prevention: A Meta-Analysis, Kathleen Yaus Wolin, Yan Yan, Graham A. Colditz, I. M. Lee

Open Access Publications

No abstract provided.


Disparities By Race And Ethnicity In Cancer Survivor Stories Available On The Web, Katherine S. Eddens, Matthew W. Kreuter, Jennifer C. Morgan, Kate E. Beatty, Sina A. Jasim, Lori Garibay, Donghua Tao, Trent D. Buskirk, Keri A. Jupka Jan 2009

Disparities By Race And Ethnicity In Cancer Survivor Stories Available On The Web, Katherine S. Eddens, Matthew W. Kreuter, Jennifer C. Morgan, Kate E. Beatty, Sina A. Jasim, Lori Garibay, Donghua Tao, Trent D. Buskirk, Keri A. Jupka

Open Access Publications

No abstract provided.


Phase Ii Study Of Continuous Daily Sunitinib Dosing In Patients With Previously Treated Advanced Non-Small Cell Lung Cancer, Silvia Novello, Giorgio V. Scagliotti, Rafael C. Rosell, Mark A. Socinski, Julie R. Brahmer, James N. Atkins, Cinta Palleres, Russell E. Burgess, Lesley Tye, Paulina Selaru, Erjian Wang, Richard Chao, Ramaswamy Govindan Jan 2009

Phase Ii Study Of Continuous Daily Sunitinib Dosing In Patients With Previously Treated Advanced Non-Small Cell Lung Cancer, Silvia Novello, Giorgio V. Scagliotti, Rafael C. Rosell, Mark A. Socinski, Julie R. Brahmer, James N. Atkins, Cinta Palleres, Russell E. Burgess, Lesley Tye, Paulina Selaru, Erjian Wang, Richard Chao, Ramaswamy Govindan

Open Access Publications

No abstract provided.


Oncogenic Hpv Infection Interrupts The Expression Of Tumor-Suppressive Mir-34a Through Viral Oncoprotein E6, Xiaohong Wang, Hsukun Wang, John P. Mccoy, Nilam Sanjib Banerjee, Janet S. Rader, Thomas R. Broker, Craig A. Meyers, Louise Chow, Zhiming Zheng Jan 2009

Oncogenic Hpv Infection Interrupts The Expression Of Tumor-Suppressive Mir-34a Through Viral Oncoprotein E6, Xiaohong Wang, Hsukun Wang, John P. Mccoy, Nilam Sanjib Banerjee, Janet S. Rader, Thomas R. Broker, Craig A. Meyers, Louise Chow, Zhiming Zheng

Open Access Publications

No abstract provided.


A Phase 2 Study Of Vorinostat In Acute Myeloid Leukemia, Eric W. Schaefer, Arturo Loaiza-Bonilla, Mark Juckett, John F. Dipersio, Vivek Roy, James Slack, Wenting Wu, Kristina Laumann, Igor Espinoza-Delgado, Steven D. Gore Jan 2009

A Phase 2 Study Of Vorinostat In Acute Myeloid Leukemia, Eric W. Schaefer, Arturo Loaiza-Bonilla, Mark Juckett, John F. Dipersio, Vivek Roy, James Slack, Wenting Wu, Kristina Laumann, Igor Espinoza-Delgado, Steven D. Gore

Open Access Publications

No abstract provided.


Neural Cadherin: A Study Of Domain 1., Elaine Ann Clark Jan 2009

Neural Cadherin: A Study Of Domain 1., Elaine Ann Clark

Honors Theses

Cadherins are a class of transmembrane proteins responsible for calcium dependent cell-cell adhesion. Classic cadherins share a common structure involving five extracellular domains, each connected by a 7 residue sequence known as a linker region. As these domains are modular in nature, this study focuses primarily on the first extracellular domain of neural cadherin without and with the adjacent linker region. NCADl and NCADl-Ll. Upon calcium binding, a tryptophan residue located in domain 1 allows for the adhesive activity of the cadherin through formation of a strand crossover structure. With the dissected NCADl and NCADl-LI, the binding pocket for calcium …