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World War I And The Mobilization Of Maternal Sacrifice: Considerations For Peace Politics, Ana C. Garner, Karen L. Slattery

College of Communication Faculty Research and Publications

No abstract provided.

Positive Psychology Within A Cultural Context, Jennifer Teramoto Pedrotti, Lisa M. Edwards, Shane J. Lopez

College of Education Faculty Research and Publications

As our capacity for communication with nations across the globe increases through the advances of technology, our interactions with others with different worldviews also become more frequent. This exposure to diversity on so many levels requires a better understanding of the multiple contexts in which people from different cultural backgrounds live and the strengths they possess that help them experience well-being. In order to define the characteristics that my be viewed as strengths in different groups, we must make efforts to remember that cultural rules and norms often dictate what can be called a strength versus a weakness. It is …

Optical Intensity-Based Long-Period Fiber Grating Biosensors And Biomedical Applications, Zhiyong Wang, Hai Xiao

Electrical and Computer Engineering Faculty Research & Creative Works

No abstract provided.

Optimal Tracking Control Of Affine Nonlinear Discrete-Time Systems With Unknown Internal Dynamics, Travis Dierks, Sarangapani Jagannathan

Electrical and Computer Engineering Faculty Research & Creative Works

In this paper, direct dynamic programming techniques are utilized to solve the Hamilton Jacobi-Bellman equation forward-in-time for the optimal tracking control of general affine nonlinear discrete-time systems using online approximators (OLA's). the proposed approach, referred as adaptive dynamic programming (ADP), is utilized to solve the infinite horizon optimal tracking control of affine nonlinear discrete-time systems in the presence of unknown internal dynamics and a known control coefficient matrix. the design is implemented using OLA's to realize the optimal feedback control signal and the associated cost function. the feedforward portion of the control input is derived and approximated using an additional …

Evaluating The Effects Of Organic And Conventional Inputs On Soil Chemical And Biological Properties In A Four-Year Vegetable Rotation And The Investigation Of Soil Microbial Properties On Plant Gene Expression, Audrey Law

University of Kentucky Doctoral Dissertations

The objective of this research was to determine the effects of conventional inputs on soil chemical and biological properties compared to organic systems in a four year vegetable rotation. Tillage and cover crops were the same in all treatments to avoid confounding factors often present in similar research. Additional experiments investigated plant gene expression in organic and conventional management systems and in soils with decreased microbial diversity. Experimental plots were prepared in the spring of 2004; four replications of three management treatments, organic, low-input and conventional, were arranged in a randomized complete block design. The rotation consisted of edamame soybean, …

The Generalized Burnside And Representation Rings, Eric B. Kahn

University of Kentucky Doctoral Dissertations

Making use of linear and homological algebra techniques we study the linearization map between the generalized Burnside and rational representation rings of a group G. For groups G and H, the generalized Burnside ring is the Grothendieck construction of the semiring of G × H-sets with a free H-action. The generalized representation ring is the Grothendieck construction of the semiring of rational G×H-modules that are free as rational H-modules. The canonical map between these two rings mapping the isomorphism class of a G-set X to the class of its permutation module …

Changes In Longitudinally Assessed Biomechanical Parameters Related To Increased Risk Of Anterior Cruciate Ligament (Acl) Injuries In Adolescent Female And Male Athletes, Kevin Ray Ford

University of Kentucky Doctoral Dissertations

Females suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate compared to male athletes participating in similar sports. Altered movement patterns and inadequate knee stiffness are two interrelated factors that may increase ACL injury risk. Onset of these neuromuscular risk factors may coincide with the rapid adolescent growth that results in the divergence of a multitude of neuromuscular parameters between sexes. The overall purpose of this dissertation was to determine if neuromuscular ACL injury risk factors in female athletes increase following rapid growth and development compared to males. Male and female athletes were tested with three-dimensional …

Promises We Have Kept: Using Grounded Theory Methodology To Understand Developmental Factors That Contribute To Caucasian Low-Income Parents Positive Assessment Of Marital Health, S. Greg Thompson

University of Kentucky Doctoral Dissertations

Low-income Caucasian married parents described lifespan processes and conditions that contributed to their individual assessments that their marriage was healthy. Spouses participated in an interview together, followed later by an individual interview with each. Interview scripts referenced the study‘s primary research questions which sought their reflections on (a) external conditions that they considered to be important to their development, and (b) personal thoughts, emotions and behaviors they deemed relevant to the success of their marriage. A third research question called for integration of participants‘ reflections into a cogent grounded theory regarding successful low-income marriages. Analysis incorporated grounded theory methods, and …

Effects Of Mindfulness And Meditation Experience On Cognitive And Emotional Functioning And Ego Depletion, Emily Lauren Brown Lykins

University of Kentucky Doctoral Dissertations

Mindfulness is increasingly recognized as an important phenomenon both clinically and empirically, with mindfulness-based interventions demonstrated to be efficacious across a wide variety of patient populations and disorders (i.e., Baer, 2003). Though debate regarding the exact definition of mindfulness continues, generally accepted definitions involve the common elements of intentionally directing attention toward the present moment and adopting an accepting, nonjudgmental, and/or nonreactive orientation, intent, or attitude (i.e., Baer et al., 2006; Bishop et al., 2004). Several testable predictions in the cognitive and emotional domains were derived from the operational definition of mindfulness provided by Bishop et al. (2004). Recent empirical …

Adolphe Nourrit, Gilbert-Louis Duprez, And Transformations Of Tenor Technique In The Early Nineteenth Century: Historical And Physiological Considerations, Jason Christopher Vest

University of Kentucky Doctoral Dissertations

The April 1837 debut of tenor Gilbert-Louis Duprez at the Paris Opéra sparked uproarious applause and inspired a new group of tenors with a different vocal technique from tenors of the previous generation. Whereas previous tenors of the nineteenth century sang in a graceful, light, and flexible style that complemented the operatic compositions of Gluck, Rossini, and Bellini, Duprez sang in a powerful, forceful voice that brought new dramatic fervor to the existing repertoire of French Grand Opera. Duprez’ stentorian vocal representations of Arnold in Rossini’s Guillaume Tell and Robert in Meyerbeer’s Robert le diable, among others, inspired composers …

Regeneration Of Damaged Growth Plate Using Igf-I Plasmid-Releasing Porous Plga Scaffolds, Nirmal Ravi

University of Kentucky Doctoral Dissertations

Growth plate injuries account for 15-30% of long bone fractures in children. About 10% of these result in significant growth disturbances due to formation of a boney bar. If not treated correctly, this can lead to life-lasting consequences of limb length inequalities and angular deformities. Current treatments for growth plate injuries include removal of boney bar and insertion of fat, silicone, bone cement, etc.. This treatment y is inadequate, leaving almost half of these patients with continued deformities. This dissertation reports characterization of a DNA–containing porous poly(lactic-co-glycolic acid) (PLGA) scaffold system, chondrogenesis using insulin-like growth factor I (IGF-I) plasmid-releasing scaffolds …

Investigations Of S-Glutathionylation Of Brain Proteins In The Progression Of Alzheimer's Disease And Of A Potential Glutatione Mimetic As A Treatment Of Alzheimer's Disease, Shelley Faye Newman

University of Kentucky Doctoral Dissertations

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by neurofibrillary tangles, senile plaques and loss of synapses. Many studies support the notion that oxidative stress plays an important role in AD pathogenesis. Previous studies from our laboratory employed redox proteomics to identify oxidatively modified proteins in the AD inferior parietal lobule (IPL). The proteins were consistent with AD pathology and have been central to further investigations of the disease. The present study was focused on the identification of specific targets of protein S-glutathionylation in AD, early AD (EAD), and mild cognative impairment (MCI) using a redox proteomics approach. In AD …

The Culture Connection: Testing A Model Of African American Attitudes Toward Mental Health Service Utilization, Andrea Michelle Smith

University of Kentucky Doctoral Dissertations

The purpose of the current study was to combine the factors previously determined to be related to African American help seeking into a single path model and, using structural equation modeling (SEM), determine the relative influence of each factor in the attitudes toward seeking mental health services (see Figure 2.2) among a community sample of African American adults from several metropolitan areas in the US. As such, SEM was utilized to compare the relative fit of two opposing models within this sample, one where a path from economic barriers to help-seeking attitudes was estimated freely and one where that path …

Applications Of Computational Fluid Dynamics To Planetary Atmospheres, Xiaolong Deng

University of Kentucky Doctoral Dissertations

Computational Fluid Dynamics (CFD) has been applied to many areas. As one of the most important fluids, the atmosphere is closely related to people’s life. Studying the atmospheres on other planets can help people understand the Earth’s atmosphere and the climate and weather phenomena in it. Because of the complexity of a planetary atmosphere and the limitation of observations, applying CFD to the study of planetary atmospheres is becoming more and more popular. This kind of CFD simulations will also help people design the mission to the extra planets.

In this dissertation, through CFD simulations, we studied the three important …

Persistent Currents And Quantum Critical Phenomena In Mesoscopic Physics, Oleksandr Zelyak

University of Kentucky Doctoral Dissertations

In this thesis, we study persistent currents and quantum critical phenomena in the systems of mesoscopic physics. As an introduction in Chapter 1 we familiarize the reader with the area of mesoscopic physics. We explain how mesoscopic systems are different from quantum systems of single atoms and molecules and bulk systems with an Avogadro number of elements. We also describe some important mesoscopic phenomena.

One of the mathematical tools that we extensively use in our studies is Random Matrix Theorty. This theory is not a part of standard physics courses and for educational purposes we provide the basics of Random …

Lipid-Based Paclitaxel And Doxorubicin Nanoparticles To Overcome P-Gp-Mediated Drug Resistance In Solid Tumors, Xiaowei Dong

University of Kentucky Doctoral Dissertations

Multidrug resistance (MDR) is a major obstacle limiting chemotherapeutic efficacy. The purpose of these studies was to investigate the potential application of injectable paclitaxel (PX) and doxorubicin (Dox)-loaded nanoparticles (NPs) engineered from oil-in-water microemulsion precursors for overcoming P-glycoprotein (P-gp)- mediated drug resistance in solid tumors.

An in-vitro study was performed to test whether the oil (stearyl alcohol and cetyl alcohol) used to make lipid nanoparticles could be metabolized. The results showed that the concentrations of the fatty alcohols within nanoparticles, which were quantitatively determined over time by gas chromatography, decreased to only 10-20% of the initial concentration after 15-24 h …

Bootstrap Enhanced N-Dimensional Deformation Of Space With Acoustic Resonance Spectroscopy, David John Link

University of Kentucky Doctoral Dissertations

Acoustic methods can often be used with limited or no sample preparations making them ideal for rapid process analytical technologies (PATs). This dissertation focuses on the possible use of acoustic resonance spectroscopy as a PAT in the pharmaceutical industry. Current good manufacturing processes (cGMP) need new technologies that have the ability to perform quality assurance testing on all products. ARS is a rapid and non destructive method that has been used to perform qualitative studies but has a major drawback when it comes to quantitative studies. Acoustic methods create highly non linear correlations which usually results in high level computations …

Exploring Lesbian And Gay Experiences With Individuals, Systems, And Environments: Patterns Of Response To Heterosexist Prejudice And Discrimination, James Russell Couch

University of Kentucky Doctoral Dissertations

While the general social climate in the U.S. has become more accepting and tolerant of sexual minority individuals, heterosexist discrimination, prejudice and violence continues to affect LGBT individuals, families and communities. While much research literature exists on the experience of minority stress and the psychological consequences of minority stress on sexual minorities, little research has been produced that examines sexual minority coping. Within the last decade, heteronegativity has been suggested as a possible coping response to heterosexism. The goal of the present study was to understand sexual minority responses to heterosexism (including heteronegativity) in a variety of contexts and circumstances. …

Alterations Of Zinc Transporters In Alzheimer's Disease, Ganna Lyubartseva

University of Kentucky Doctoral Dissertations

Alzheimer’s disease (AD), one of the major causes of disability and mortality in Western societies, is a progressive age-related neurodegenerative disorder. Increasing evidence suggests the etiology of AD may involve disruptions of zinc (Zn) homeostasis. We hypothesize that disruption of Zn homeostasis leads to alterations of Zn transporter (ZnT) proteins, resulting in increased production of neurotoxic amyloid beta (Aβ) peptide in AD brain. To address this hypothesis we carried out the following studies.

1. We characterized alterations of ZnT-1, ZnT-4 and ZnT-6 in the brain of preclinical AD (PCAD) subjects, who show no overt clinical manifestations of AD but demonstrate …

Examining The Construct Of Perfectionism: A Factor-Analytic Study, Agnes Mariann Stairs

University of Kentucky Doctoral Dissertations

The construct of perfectionism is related to many important outcome variables. However, the term “perfectionism” has been defined in many different ways, and items comprising the different existing scales appear to be very different in content. The overarching aim of the present set of studies was to help clarify the specific unidimensional constructs underlying what is called “perfectionism”. First, trained raters reliably sorted items from existing measures of perfectionism into nine dimensions. An exploratory factor analysis, followed by a confirmatory factor analysis on an independent sample, resulted in a 9 scale, 61 item measure, called the Measure of Constructs Underlying …

Analysis Of Security Measures For Sequences, Ramakanth Kavuluru

University of Kentucky Doctoral Dissertations

Stream ciphers are private key cryptosystems used for security in communication and data transmission systems. Because they are used to encrypt streams of data, it is necessary for stream ciphers to use primitives that are easy to implement and fast to operate. LFSRs and the recently invented FCSRs are two such primitives, which give rise to certain security measures for the cryptographic strength of sequences, which we refer to as complexity measures henceforth following the convention. The linear (resp. N-adic) complexity of a sequence is the length of the shortest LFSR (resp. FCSR) that can generate the sequence. Due …

Paleogeographic Reconstructuion Of The St. Lawrence Promontory, Western Newfoundland, John Stefan Allen

University of Kentucky Doctoral Dissertations

Neoproterozoic-Early Cambrian continental rifting related to the breakup of the supercontinent Rodinia framed the continental margin of eastern Laurentia and the departing cratons around the opening Iapetus Ocean. The result of continental extension was the production of a zig-zag set of promontories and embayments on the eastern Laurentian margin defined by northeast-trending rift segments offset by northwesttrending transform faults.

The St. Lawrence promontory defines the Laurentian margin in western Newfoundland. There, Neoproterozoic-Carboniferous clastic, volcanic, and carbonate successions record protracted continental rifting and passive-margin thermal subsidence followed by destruction of the margin during the early, middle, and late Paleozoic Appalachian orogenic …

Experimental And Molecular Dynamics Simulation Studies Of Partitioning And Transport Across Lipid Bilayer Membranes, Ravindra Wadhumal Tejwani

University of Kentucky Doctoral Dissertations

Most drugs undergo passive transport during absorption and distribution in the body. It is desirable to predict passive permeation of future drug candidates in order to increase the productivity of the drug discovery process. Unlike drug-receptor interactions, there is no receptor map for passive permeability because the process of transport across the lipid bilayer involves multiple mechanisms. This work intends to increase the understanding of permeation of drug-like molecules through lipid bilayers.

Drug molecules in solution typically form various species due to ionization, complexation, etc. Therefore, species specific properties must be obtained to bridge the experiment and simulations. Due to …

Using Thr Ffm To Understand And Integrate The Deficits Of Psychopathy, Karen J. Derefinko

University of Kentucky Doctoral Dissertations

Psychopathy is associated with several behavioral and psychophysiological deficits. Lynam (2002) has argued that the use of an overarching conceptualization of psychopathy can provide a parsimonious explanation of psychopathic pathology. The current study examined relations between tasks used to explore psychopathic pathology and dimensions from the Five Factor Model of personality. Undergraduate participants completed the NEO PI-R, the BART, a go/no-go task, an emotional morph task, and provided physiological responses to stimuli. While hypothesized relations to FFM psychopathy composites were generally unsupported, other interesting relations to traits were identified. Results indicated that hypoarousal to negative stimuli was negatively related to …

Viable Institutions, Judicial Power, And Post-Communist Constitutional Courts, Kirill Mikhaylovich Bumin

University of Kentucky Doctoral Dissertations

In pursuing their goals, newly-created constitutional courts of Eastern Europe and the former Soviet republics are affected by their institutional setting and capabilities. Yet, previous studies did not explore how constitutional courts develop over time and what noteworthy implications for politics and society result from their institutional growth. To address this gap in the literature, I measured a variety of organizational characteristics and constructed an index of institutional development for the twenty eight constitutional courts in the post-communist countries from the initial year of their transitions through 2005. I argued that high values on this measure (which I labeled the …

Aspects Of The Geometry Of Metrical Connections, Matthew J. Wells

University of Kentucky Doctoral Dissertations

Differential geometry is about space (a manifold) and a geometric structure on that space. In Riemann’s lecture (see [17]), he stated that “Thus arises the problem, to discover the matters of fact from which the measure-relations of space may be determined...”. It is key then to understand how manifolds differ from one another geometrically. The results of this dissertation concern how the geometry of a manifold changes when we alter metrical connections. We investigate how diverse geodesics are in different metrical connections. From this, we investigate a new class of metrical connections which are dependent on the class of smooth …

Imide-Functionalized Conjugated Polymers: Synthesis, Structure-Property And Device Studies, Xugang Guo

University of Kentucky Doctoral Dissertations

Organic semiconductors are widely studied as potential active components for consumer electronics due largely to their easily tuned properties and the promise of lower-cost solution-based processing technology. Imide-functionalized organic small molecule compounds have been one of the more important and studied organic semiconductors. However, very few imide-functionalized conjugated polymers have been reported in the literature. The body of this dissertation focuses on the synthesis, structure-property and device studies of imide-functionalized conjugated polymers. Reasons for choosing arylene imides as polymer building blocks include: a) they impart low-lying LUMOs to polymers, allowing band-gap engineering through choice of comonomers with variable electron-donating ability; …

Investigation Of Surface Fine Grained Laminae, Streambed, And Streambank Processes Using A Watershed Scale Hydrologic And Sediment Transport Model, Joseph Paul Russo

University of Kentucky Doctoral Dissertations

Sediment transport at the watershed scale in the Bluegrass Region of Kentucky is dominated by surface fine grained laminae, streambed, and streambank erosion; high instream sediment storage; and surface erosion processes. All these processes can be impacted by agricultural, urban, and suburban land-uses as well as hydrologic forcing. Understanding sediment transport processes at the watershed scale is a need for budgeting and controlling sediment pollution, and watershed modeling enables investigation of the cumulative effect of sediment processes and the parameters controlling these processes upon the entire sediment budget for a watershed. Sediment transport is being modeled by coupling the hydrologic …

Pattern Recognition Integrated Sensing Methodologies (Prisms) In Pharmaceutical Process Validation, Remote Sensing And Astrobiology, Thaddaeus S. Hannel

University of Kentucky Doctoral Dissertations

Modern analytical instrumentation is capable of creating enormous and complex volumes of data. Analysis of large data volumes are complicated by lengthy analysis time and high computational demand. Incorporating real-time analysis methods that are computationally efficient are desirable for modern analytical methods to be fully utilized. The use of modern instrumentation in on-line pharmaceutical process validation, remote sensing, and astrobiology applications requires real-time analysis methods that are computationally efficient.

Integrated sensing and processing (ISP) is a method for minimizing the data burden and sensing time of a system. ISP is accomplished through implementation of chemometric calculations in the physics of …

Long-Period Ground Motions In The Upper Mississippi Embayment From Finite-Fault, Finite-Difference Simulations, Kenneth A. Macpherson

University of Kentucky Doctoral Dissertations

A 3D velocity model and 3D wave propagation code have been employed to simulate long-period ground motions in the upper Mississippi embayment. This region is exposed to seismic hazard in the form of large earthquakes in the New Madrid seismic zone and observational data are sparse, making simulation a valuable tool for predicting the effects of large events. These simulations were undertaken in order to estimate ground-motion characteristics and to investigate the influence of the 3D embayment structure and finite-fault mechanics. There are three primary fault zones in the New Madrid seismic zone, each of which was likely associated with …