Digital Commons Network^™

Manipulating Embryonic Neural Precursor Cells For Therapeutic Transplantation Into A Rat Model Of Neuropathic Pain, Orion Furmanski

Open Access Dissertations

Persons with spinal cord injury (SCI) suffer life-long consequences including paralysis, loss of involuntary bodily functions, and chronic pain. A subset of SCI patients develop neuropathic pain (NP), a chronic condition resulting from damage to the spinal cord. Hyperexcitability of spinal cord sensory neurons near damaged tissue is believed to underlie SCI-related NP. Although many therapies have been employed clinically to combat SCI-NP, few give satisfactory long-term relief. Transplantation of cells that release GABA, a molecule that inhibits neuronal activity, is being explored as an alternative to current SCI-NP therapies. My experiments made progress toward preclinical modeling of GABA cell …

2009 Winter Boise State University Commencement Program

Commencement Programs

No abstract provided.

Minutes, Crummer Graduate School Of Business Faculty Meeting, Friday, December 18, 2009, Crummer Graduate School Of Business Faculty

Crummer Graduate School of Business Minutes and Reports

No abstract provided.

Imposes Additional Tax On Cigarettes For Cancer Research. Initiative Statute.

Initiatives

Imposes additional five cent tax on each cigarette distributed ($1.00 per pack), and an equivalent tax increase on other tobacco products, to fund cancer research and other specified purposes. Requires tax revenues be deposited into a special fund to finance research and research facilities focused on detecting, preventing, treating, and curing cancer, heart disease, emphysema, and other tobacco-related diseases, and to finance prevention programs. Creates nine-member committee charged with administering the fund. Summary of estimate by Legislative Analyst and Director of Finance of fiscal impact on state and local government: Increase in new cigarette tax revenues of about $850 million …

T Cell Receptor Cross-Reactivity Directed By Antigen-Dependent Tuning Of Peptide-Mhc Molecular Flexibility, Oleg Y. Borbulevych, Kurt H. Piepenbrink, Brian E. Gloor, Daniel R. Scott, Ruth F. Sommese, David K. Cole, Andrew K. Sewell, Brian M. Baker

Food for Health: Publications

Tell mediated immunity requires T cell receptor (TCR) cross-reactivity, the mechanisms behind which remain incompletely elucidated. The αβ TCR A6 recognizes both the Tax (LLFGYPVYV) and Tel1p (MLWGYLQYV) peptides presented by the human class I MHC molecule HLA-A2. Here we found that although the two ligands are ideal structural mimics, they form substantially different interfaces with A6, with conformational differences in the peptide, the TCR, and unexpectedly, the MHC molecule. The differences between the Tax and Tel1p ternary complexes could not be predicted from the free peptide-MHC structures and are inconsistent with a traditional induced-fit mechanism. Instead, the differences were …

Active Vibration Control Of Essential Tremor, Sri Sitaram Chowdary Lavu, Abhijit Gupta

NIU Bibliography

Essential Tremor is the most common form of pathological tremor and is a major source of functional disability, affecting many of the daily living tasks. Essential tremor appears usually after the fourth decade and is slowly progressive. This paper is related to the active vibration control of the tremor of hand. Active vibration control has been successfully implemented in the past to control the vibrations of structures. In this study, a PID controller has been designed using MATLAB/SIMULINK. The PID controller has been loaded in the DS1104 processor. Experiments have been conducted on a beam and an artificial arm. A …

The Negative Images Of Nursing Portrayed On Grey’S Anatomy, House And Er And Its Effect On Public Perception And The Contemporary Nursing Shortage, Jacquelyn Bishop

Health Sciences Student Scholarship

No abstract provided.

A Comparison Of The Wellbeing Of Orphans And Abandoned Children Ages 6–12 In Institutional And Community-Based Care Settings In 5 Less Wealthy Nations, Kathryn Whetten, Jan Ostermann, Rachel A. Whetten, Brian W. Pence, Karen O'Donnell, Lynne C. Messer, Nathan M. Thielman, The Positive Outcomes For Orphans (Pofo) Research Team

Faculty Publications

Background

Leaders are struggling to care for the estimated 143,000,000 orphans and millions more abandoned children worldwide. Global policy makers are advocating that institution-living orphans and abandoned children (OAC) be moved as quickly as possible to a residential family setting and that institutional care be used as a last resort. This analysis tests the hypothesis that institutional care for OAC aged 6–12 is associated with worse health and wellbeing than community residential care using conservative two-tail tests.

Methodology

The Positive Outcomes for Orphans (POFO) study employed two-stage random sampling survey methodology in 6 sites across 5 countries to identify 1,357 …

Regulation Of Cellular Protein Phosphatase-1 (Pp1) By Phosphorylation Of The Cpi-17 Family, C-Kinase-Activated Pp1 Inhibitors., Masumi Eto

Department of Molecular Physiology and Biophysics Faculty Papers

The regulatory circuit controlling cellular protein phosphatase-1 (PP1), an abundant group of Ser/Thr phosphatases, involves phosphorylation of PP1-specific inhibitor proteins. Malfunctions of these inhibitor proteins have been linked to a variety of diseases, including cardiovascular disease and cancer. Upon phosphorylation at Thr(38), the 17-kDa PP1 inhibitor protein, CPI-17, selectively inhibits a specific form of PP1, myosin light chain phosphatase, which transduces multiple kinase signals into the phosphorylation of myosin II and other proteins. Here, the mechanisms underlying PP1 inhibition and the kinase/PP1 cross-talk mediated by CPI-17 and its related proteins, PHI, KEPI, and GBPI, are discussed.

Fall 2009 Commencement Program, University Of Alabama In Huntsville

Commencement Programs

No abstract provided.

Identifying Blood Biomarkers And Physiological Processes That Distinguish Humans With Superior Performance Under Psychological Stress., Amanda M. Cooksey, Nausheen Momen, Russell Stocker, Shane C. Burgess

CVM Publications

BACKGROUND: Attrition of students from aviation training is a serious financial and operational concern for the U.S. Navy. Each late stage navy aviator training failure costs the taxpayer over $1,000,000 and ultimately results in decreased operational readiness of the fleet. Currently, potential aviators are selected based on the Aviation Selection Test Battery (ASTB), which is a series of multiple-choice tests that evaluate basic and aviation-related knowledge and ability. However, the ASTB does not evaluate a person's response to stress. This is important because operating sophisticated aircraft demands exceptional performance and causes high psychological stress. Some people are more resistant to …

University Of Nebraska At Omaha, December Commencement 2009, University Of Nebraska At Omaha

Commencement Programs

No abstract provided.

Af17 Competes With Af9 For Binding To Dot1a To Up-Regulate Transcription Of Epithelial Na+ Channel Α, Mary R. Reisenauer, Marc Anderson, Le Huang, Zhijing Zhang, Qiaoling Zhou, Bruce C. Kone, Andrew P. Morris, Gene D. Lesage, Stuart E. Dryer, Wenzheng Zhang

ETSU Faculty Works

We previously reported that Dot1a*AF9 complex represses transcription of the epithelial Na+ channel subunit α (α-ENaC) gene in mouse inner medullary collecting duct mIMCD3 cells and mouse kidney. Aldosterone relieves this repression by down-regulating the complex through various mechanisms. Whether these mechanisms are sufficient and conserved in human cells or can be applied to other aldosterone-regulated genes remains largely unknown. Here we demonstrate that human embryonic kidney 293T cells express the three ENaC subunits and all of the ENaC transcriptional regulators examined. These cells respond to aldosterone and display benzamil-sensitive Na+ currents, as measured by whole-cell patch clamping. We also …

Virtual Intermediaries Ii - Canadian Solutions (Drop Shipments) Compared With Us, Japanese & Eu Approaches, Richard Thompson Ainsworth

Faculty Scholarship

Virtual travel agents are opportunistic internet-based travel agents. They are intermediary businesses that create mutually beneficial three-party transactions that secure accommodations for a traveler that: (a) meet the basic needs of the traveler (at a discount), (b) fills vacant room for accommodation retailers with guests that pay below market, but above standard costs, and (c) profit from the extra cash, the margin in the transaction.

The virtual intermediary’s eye is always on the discount and the cash flow. One of the things that catches their attention are the accommodation taxes which they collect from the traveler in advance and remit …

Winter Commencement: December 18, 2009, University Of North Dakota

UND Commencement Programs

UND Winter Commencement program from December 18, 2009.

Study Finds Greenhouse Gas Carbon Dioxide Ramps Up Aspen Growth, University Relations

Campus News Archive

Chris Cole, professor of biology, and Jon Anderson, professor of mathematics, and Wisconsin colleagues find a surprising response to carbon dioxide.

Discovery Of Very High Energy Gamma Rays From Pks 1424+240 And Multiwavelength Constraints On Its Redshift, P. T. Reynolds, Et Al

Physical Sciences Publications

We report the first detection of very high energy83Gamma-ray emission above 100 GeV. (VHE) gamma-ray emission above 140 GeV from PKS 1424+240, a BL Lac object with an unknown redshift. The photon spectrum above 140 GeV measured by VERITAS is well described by a power law with a photon index of 3.8 ± 0.5stat ± 0.3syst and a flux normalization at 200 GeV of (5.1 ± 0.9stat ± 0.5syst) × 10–11 TeV–1 cm–2 s–1, where stat and syst denote the statistical and systematical uncertainties, respectively. The VHE flux is steady over the observation period between MJD 54881 and 55003 (from …

The Legal Origins Theory In Crisis, Lisa M. Fairfax

BYU Law Review

No abstract provided.

Rethinking The "Law And Finance" Paradigm, Katharina Pistor

BYU Law Review

No abstract provided.

Contemporary Legal Transplants: Legal Families And The Diffusion Of (Corporate) Law, Holger Spamann Spamann

BYU Law Review

No abstract provided.

The Murray Ledger And Times, December 18, 2009, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Effective Blended Family Ministry In The Twenty-First Century Church, Ronald Lee Beck

Doctoral Dissertations and Projects

The Blended or Step family is the number one family unit in the United States today. As a result, it is imperative that the New Testament Church learn to more effectively minister to the needs of this growing family group. Although the blended family has many issues, six of the more prevalent issues are discussed in this thesis with solutions given to help any family in the blending process to have a better chance of success.

Dedication, The Board Of Editors

Western New England Law Review

No abstract provided.

Can Green Roofs Provide Habitat For Urban Bees (Hymenoptera: Apidae)?, Sheila R. Colla, Erin Willis, Laurence Packer

Cities and the Environment (CATE)

Increasing urbanization of many regions of the world has resulted in the decline of suitable habitat for wild flora and fauna. Green roofs have been suggested as a potential avenue to provide patches of good-quality habitat in highly developed regions. In this study, we surveyed green roofs in Toronto, Ontario, Canada for bee diversity and abundance to determine their potential as quality habitats in an urban area for these important pollinators. By comparing various biodiversity measures between green roofs and ground-level sites, we show that green roofs provide habitat to many bee species. Implications for pollinator conservation and urban agricultural …

Modification Of A Community Garden To Attract Native Bee Pollinators In Urban San Luis Obispo, California, Jaime Pawelek, G W. Frankie, Robbin W. Thorp, Maggie Przybylski

Cities and the Environment (CATE)

Gardens have become increasingly important places for growing nutritional food, for conserving biodiversity, for biological and ecological research and education, and for community gathering. Gardens can also be designed with the goal of attracting aesthetically pleasing wildlife and pollinators, like birds and butterflies, but other important garden visitors, like bees, can also be drawn to specially planned and modified gardens. A community garden in San Luis Obispo, California provided the setting for modification with the goal of attracting native bee pollinators by planting known bee-attractive plants. The local gardeners participated in a survey questionnaire and focused interviews to provide their …

Introduction To Urban Pollinators And Community Gardens Issue, Eric G. Strauss

Cities and the Environment (CATE)

Introduction

Constitutional Law—The "Choose-Life" Specialty Plate Cases: Standing To Sue When The Government Manipulates Public Debate, Layla G. Taylor

Western New England Law Review

No abstract provided.

A Conductor's Guide To Two Cantatas By Philipp Heinrich Erlebach: Ich Will Wasser Giessen And Christus Ist Mein Leben, Tobin Christopher Sparfeld

Open Access Dissertations

Philipp Heinrich Erlebach (1657-1714) was a court composer and music director in the central German town of Schwarzburg-Rudolstadt. During his day, Erlebach mastered nearly every genre of his era and turned the court of Rudolstadt into a sophisticated musical center. Unfortunately, a fire which consumed the Rudolstadt court in 1735 destroyed many of his sacred and secular manuscripts. Erlebach had a marked influence on the development of the sacred cantata. He was one of the first composers to write a cycle of texts by Erdmann Neumeister, the earliest cycle of Neumeister cantatas that survives. This study provides background and analysis …

Biology Of Amacrine Cells And Retinal Ganglion Cells In The Developing Retina, Noelia J. Kunzevitzky

Open Access Dissertations

How do neighboring neurons differ? How are they similar? How do they relate to each other? Retinal ganglion cells (RGCs) and amacrine cells are born during the same developmental window, from the same population of progenitor cells, and some amacrine cells even migrate to the same retinal layer where RGCs reside, the ganglion cell layer. Amacrine cells are presynaptic to RGCs, whose axons subsequently project through the optic nerve and carry visual information to the brain. Although the cell biology of RGCs has been studied in some detail, relatively little is known about the cell and molecular biology of amacrine …

Gsu View, 2009-12-17, Office Of Public Affairs

GSU View

Newsletter published by Governors State University 2007-current.