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Identification Of The Downstream Effector Genes Involved In Hoxb4-Induced Expansion Of Hematopoietic Progenitor Cells, Jie Jiang

Theses and Dissertations (ETD)

Overexpression of HOXB4, a member of Homeobox transcription factor family, promotes expansion of hematopoietic stem and progenitor cells bothin vivo and in vitro. However, the molecular mechanisms underlying this effect are not well understood. In order to identify direct target genes of HOXB4 in primary murine hematopoietice progenitor cells, we induced HOXB4 function in lineage-negative, murine bone marrow cells, using a tamoxifen-inducibleHOXB4-ER^T2fusion protein. Seventy seven genes with differentially changed expression in early response to HOXB4 have been identified as candidate target genes. Among them, we show that Hemogen (Hemgn), encoding a nuclear protein specifically …

Statistical Analysis Of Linear Analog Circuits Using Gaussian Message Passing In Factor Graphs, Miti Phadnis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This thesis introduces a novel application of factor graphs to the domain of analog circuits. It proposes a technique of leveraging factor graphs for performing statistical yield analysis of analog circuits that is much faster than the standard Monte Carlo/Simulation Program With Integrated Circuit Emphasis (SPICE) simulation techniques. We have designed a tool chain to model an analog circuit and its corresponding factor graph and then use a Gaussian message passing approach along the edges of the graph for yield calculation. The tool is also capable of estimating unknown parameters of the circuit given known output statistics through backward message …

Age Effects On Iron-Based Pipes In Water Distribution Systems, Ryan T. Christensen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Pipes in water distribution systems may change as they age. The accumulation of corrosion byproducts and suspended particles on the inside wall of aged pipes can increase pipe roughness and reduce pipe diameter. To quantify the hydraulic effects of irregular accumulation on the pipe walls, eleven aged pipes ranging in diameter from 0.020-m (0.75-in) to 0.100-m (4-in) and with varying degrees of turberculation were located and subjected to laboratory testing. The laboratory test results were used to determine a relationship between pipe diameter reduction and Hazen-Williams C. This relationship, combined with a manipulation of the Hazen-Williams equation, provided a simple …

"The Life And Miracles Of Fisher Alumna Katie Kreutter, 2009", Katie Kreutter

Verbum

In lieu of an abstract, below is the essay's first paragraph.

"I still find it difficult to believe that I am writing this submission for Verbum as a Fisher alumnus, and that soon a full semester will have passed since I was enrolled as a full-time student. Looking back on my time at Fisher, I fondly recall courses and professors that positively impacted the quality of my educational experience, as well as clubs and students that similarly supported my social experience. While I do not consider myself to have any sage advice to offer current students, I will say that …

Climate Change Impacts On Water Resources Of The Upper Blue Nile River Basin, Ethiopia, U. Kim, Jagath J. Kaluarachchi, V. U. Smakhtin

Civil and Environmental Engineering Faculty Publications

Climate change affects water resources availability of international river basins that are vulnerable to runoff variability of upstream countries especially with increasing water demands. The upper Blue Nile River Basin is a good example because its downstream countries, Sudan and Egypt, depend solely on Nile waters for their economic development. In this study, the impacts of climate change on both hydrology and water resources operations were analyzed using the outcomes of six different general circulation models (GCMs) for the 2050s. The outcomes of these six GCMs were weighted to provide average future changes. Hydrologic sensitivity, flow statistics, a drought index, …

Current Status And Recent Developments In Australia’S National Space Law And Its Relevance To Space Law And Space Activities In The Pacific Rim, Ricky J. Lee

Journal of Space Law

No abstract provided.

Current Status And Recent Developments In Japan’S National Space Law And Its Relevance To Pacific Rim Space Law And Activities, Setsuko Aoki

Journal of Space Law

No abstract provided.

Bibliography: Aviation And Space Law: Relevant Publications, P. J. Blount

Journal of Space Law

No abstract provided.

The Impact Of An Urban Wal-Mart Store On Area Businesses: An Evaluation Of One Chicago Neighborhood's Experience, Center For Urban Research And Learning, Julie Davis, David Merriman, Lucia Samayoa, Brian Flanagan, Ron Baiman, Joseph Persky

Center for Urban Research and Learning: Publications and Other Works

Having achieved nearly complete coverage of non-urban and suburban markets, mega-retailer Wal-Mart has turned its attention to urban expansion. Evaluations of Wal-Mart’s impact on urban retail businesses and local employment are necessary to inform policy makers, scholars, and community activists looking to improve economic opportunities for inner-city residents. This study focuses on the Wal-Mart store that opened on the West Side of Chicago in September 2006.

Reactivity Of Phenyldi(2-Thienyl)Phosphine Towards Group 7 Metal Carbonyls: Carbon–Phosphorus Bond Activation, Shishir Ghosh, Alok K. Das, Noorjahan Begum, Daniel T. Haworth, Sergey V. Lindeman, James R. Gardinier, Tasneem A. Siddiquee, Dennis W. Bennett, Ebbe Nordlander, Graeme Hogarth, Shariff E. Kabir

Chemistry Faculty Research and Publications

Addition of phenyldi(2-thienyl)phosphine (PPhTh₂) to [Re₂(CO)_10−n(NCMe)_n] (n = 1, 2) affords the substitution products [Re₂(CO)_10−n(PhPTh₂)_n] (1, 2) together with small amounts of fac-[ClRe(CO)₃(PPhTh₂)₂] (3) (n = 2). Reaction of [Re₂(CO)₁₀] with PPhTh₂in refluxing xylene affords a mixture which includes 2, [Re₂(CO)₇(PPhTh₂)(μ-PPhTh)(μ-H)] (4), [Re₂(CO)₇(PPhTh₂)(μ-PPhTh)(μ-η¹,κ¹(S)-C₄H₃S)] (5) and …

Fiscal Year 2009 Fhwa-536 Report For The Kentucky Transportation Cabinet, Steven Douglas Kreis, Candice Y. Wallace

Kentucky Transportation Center Research Report

The Federal Highway Administration (FHWA) requires state transportation agencies to submit a biennial report on local highway finances. The purpose of these reports is to provide FHWA with the data it needs to capture the financing of highway activities at the local level. Based on this information, it can identify trends in revenue, expenditures, investments, and program development, and in turn make decisions about future investments. The report, FHWA-536, asks agencies to report on four areas of local highway finance: 1) disposition of highway-user revenues; 2) revenues used for roads and streets identified by source and funding type; 3) road …

Synchronization And Media Exchange In Large-Scale Caenorhabditis Elegans Cultures, Jason D. Brown

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The nematode Caenorhabditis elegans is a model organism for understanding sensory molecules of multicellular organisms. Ovulating hermaphrodites produce putative pheromone(s) that cause male attraction. Because pheromones are produced in such small quantities, adult conditioned-media from large-scale synchronous culture is necessary to analyze these pheromones. Current protocols for culture synchronization have volume constraints that limit large-scale synchronous cultures and current methodology for adult conditioned-media production is impractical.

Modification of Tangential Flow Filtration (TFF) systems was investigated for use as a method to increase the volume limits of bleach egg harvest for C. elegans culture synchronization. Also, an adult retention device built …

Design, Test, And Calibration Of The Utah State University Floating Potential Probe, Jessica D. Gregory

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The ionosphere is a conducting layer in the Earth's upper atmosphere and is the nearest naturally occurring plasma environment. Inherent to all plasma environments is an electric field. Currently, the double electric field probe is the most successful instrument for measuring the electric fields of space plasmas. Utah State University/Space Dynamics Lab has developed a double electric field probe, called the Floating Potential Probe (FPP), with a slightly different instrumentation approach than what has been done previously. The FPP is one component of a suite of instruments that launched in fall of 2007 from Wallops Island, Virginia, as part of …

Removal And Utilization Of Wastewater Nutrients For Algae Biomass And Biofuels, Erick W. Griffiths

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Logan City Environmental Department operates a facility that consists of 460 acres of fairly shallow lagoons (~ 5'deep) for biological wastewater treatment that meets targets for primary and secondary treatments (solids, biological oxygen demand (BOD), and pathogen removal). Significant natural algal growth occurs in these lagoons, which improves BOD removal through oxygenation and also facilitates N removal through volatilization as ammonia under high pH conditions created by algal growth. Phosphorus, however, is non-volatile and stays in the water and likely cycles in and out of algal cells as they grow and die in the lagoons. In the near future, …

Evaluation Of Industrial Promoted Agroforestry In Andhra Pradesh And Madhya Pradesh, India, Brian D. Mcdonald

Graduate Theses, Dissertations, and Problem Reports (ETD)

In many parts of the world, pulp and paper companies are becoming heavily dependent on private agroforestry schemes. With growing demand for wood fiber and limited commercial land to grow it on, the forest industry is continually turning to private farmers and individuals to contract timber. In order to alleviate this problem, many companies have turned to out-grower schemes to supply wood to the mills. Local farmers now have the opportunity to benefit from company extension and supplies, and in return, the company can guarantee its supply of raw materials.;A recent trend in agriculture is adding trees to farmers? traditional …

Synthesis And Spectroscopic Characterization Of Nanostructured Thermoelectric Materials, Jason Reppert

All Dissertations

Bismuth in the bulk form is a semimetal with a rhombohedral structure. It has a small band overlap between the conduction and valence bands and a highly anisotropic electron effective-mass tensor. Thermoelectric materials, in which one of the three dimensions is in the nanometer regime, exhibit unique quantum confinement properties and have generated much interest in recent years. Theoretical investigations have suggested that nanowires with diameters ≤ 10 nm will possess a figure-of-merit ZT > 2. Prior to this study, it has been shown that Bi nanowires with small enough diameters (~10 nm), prepared via the pulsed laser vaporization method, undergo …

Some New Problems In Changepoint Analysis, Jonathan Woody

All Dissertations

Climatological studies have often neglected changepoint effects when modeling
various physical phenomena. Here, changepoints are plausible whenever a station location moves or its instruments are changed. There is frequently meta-data to
perform sound statistical inferences that account for changepoint
information. This dissertation focuses on two such problems in changepoint analysis.
The first problem we investigate involves assessing trends
in daily snow depth series. Here, we introduce a stochastic storage model. The model allows for seasonal features, which permits the
analysis of daily data. Changepoint times are shown to greatly influence estimated trends in one snow depth series and are accounted …

On The Testing And Estimation Of High-Dimensional Covariance Matrices, Thomas Fisher

All Dissertations

Many applications of modern science involve a large number of parameters. In
many cases, the number of parameters, p, exceeds the number of observations,
N. Classical multivariate statistics are based on the assumption that the
number of parameters is fixed and the number of observations is large. Many of
the classical techniques perform poorly, or are degenerate, in high-dimensional
situations.
In this work, we discuss and develop statistical methods for inference of
data in which the number of parameters exceeds the number of observations.
Specifically we look at the problems of hypothesis testing regarding and the
estimation of the covariance …

Inter-Tube Bonding And Defects In Carbon Nanotubes And The Impact On The Transport Properties And Micro-Morphology, Keqin Yang

All Dissertations

The transport properties of the carbon nanotubes (CNTs) are affected by the tube-tube interaction and the defects presented in the system. Inter-tube bonding, formed during spark plasma sintering (SPS) process, lowers the electrical/thermal resistivity at the tube-tube junctions and also causes new scattering mechanisms such as strong electron-phonon coupling (EPC) at low temperature. More evidences have been found by changing the SPS temperature and doping the CNTs to support the electron-phonon coupling is Kohn anomaly (KA) in as-SPSed CNTs. The phonon drag, appearing in thermoelectric power (TEP) of the as-SPSed CNTs at low temperature, can be explained in the framework …

Creation Of Bioactive Surfaces To Modulate Cell Behavior Using Surface Initiated Photoiniferter-Mediated Graft Photopolymerization, Nihar Shah

All Dissertations

Biomaterials widely used in biomedical applications still face biocompatibility issues arising from non-specific protein adsorption on the foreign surface, and the consequent undesired cell response. Emerging evidence suggests that imparting specific bioactivity to the biomaterial's surface to elicit favorable response from cells, (like osseointegration of joint implants and endothelialization of stents) can yield much better biocompatibility results when combined with passive prevention of protein adsorption. In more complex diseases like spinal cord injury and cardiomyopathy, specific biomolecules are required to elicit desired cell responses for successful regeneration. However, for success of such biomolecule based strategies, the effects of various parameters …

Metal Oxide And Mercuric Sulfide Nanoparticles Synthesis And Characterization, Xin Xu

All Dissertations

Increasing applications of nanoparticles (NPs), such as metal oxide and mercuric sulfide NPs, lead to heightened environmental concern. Challenges to the study of natural and engineered NPs include the physical and chemical characterizations.
Commercially available and laboratory-synthesized metal based NPs, iron oxide (Fe2O3), copper oxide (CuO), titanium dioxide (TiO2), zinc oxide (ZnO) and mercuric sulfide (HgS) were studied by comprehensive characterizations methods. The general synthesis process was modified sol-gel method. The size and morphology of NPs could be influenced by temperature, sonication, calcination, precursor concentration, pH and types of reaction media. In the synthesis of nZnO in ethanol, the essential …

Real-Time Vehicle Parameter Estimation And Adaptive Stability Control, John Limroth

All Dissertations

This dissertation presents a novel Electronic Stability Control (ESC) strategy that is capable of adapting to changing vehicle mass, tire condition and road surface conditions. The benefits of ESC are well understood with regard to assisting drivers to maintain vehicle control during extreme handling maneuvers or when extreme road conditions such as ice are encountered. However state of the art ESC strategies rely on known and invariable vehicle parameters such as vehicle mass, yaw moment of inertia and tire cornering stiffness coefficients. Such vehicle parameters may change over time, especially in the case of heavy trucks which encounter widely varying …

The Development Of A Mesenchymal Stem Cell Based Bone Graft System, Sarina Sinclair

All Dissertations

Greater than 5.5 million fractures are sustained by Americans each year, accounting for more than 500,000 bone graft surgeries. Bone grafts are the second most transplanted material, surpassed only by blood. The current 'gold standard' for bone grafting involves harvesting bone material from the patient's iliac crest, due to its osteoinductive properties. Unfortunately, the surgery required to harvest material from the iliac crest causes additional pain for the patient, relies on a limited amount of available bone tissue, and results in, on average, a 30% rate of donor site morbidity. Both natural and synthetic substitutes have been developed to avoid …

Dynamics Of Ultrasonic Consolidation, James Gibert

All Dissertations

Ultrasonic consolidation (UC) is a solid state rapid manufacturing process derived from ultrasonic welding of thin metal foils coupled with contour milling to achieve functional accurate components. The bonding of metal is accomplished by the local application of high frequency vibration energy under pressure producing a metallurgical bond without melting the base material. Its unique nature allows the design and fabrication of structural panels for satellites, production of injection molding tools, functionally graded structures, metal-matrix composites, embedded sensors, armor, and fiber embedded adaptive structures. It is commonly theorized that interfacial motion and friction at the bonding interface play a prominent …

Characterization Of Escherichia Coli Related To Construction Site Sediment Basins, Calvin Sawyer

All Dissertations

Large construction sites can have significant temporary and permanent impacts on the physical landscape. Excess sediment is frequently deposited into nearby surface waters, altering benthic habitat, reducing water clarity and transporting other pollutants such as enteric bacteria. To capture eroded soil and attenuate storm discharge peaks, many permitted construction projects larger than 10 acres in South Carolina require the installation of a sediment basin. Sediment-laden runoff is routed to a newly excavated impoundment, where larger particles settle out of suspension. Thus an entirely new hydrologic feature designed to concentrate eroded sediment and water is introduced into the landscape.
Eight construction …

Automatic Extracted Object Technique For Contrast Enhancement Medical Images, Raffia's Talib, Atheer Jabbar Mansor

Iraqi Journal of Computers, Communications, Control and Systems Engineering

The aim of this work is a proposed system to enhance automatically the contrast of the desired region in the medical image to get the wanted information without enhancing the contrast of the whole image. The proposed system includes the automatic extraction process, the automatic contrast enhancement process and finally reinsertion process for region in the image. Threshold, smoothing, boundary extraction, chain code or region filling techniques were used in the automatic extraction process. While, histogram equalization, histogram stretching, gray level grouping (GLG), fast gray level grouping (FGLG) or auto-contrast techniques were used in the automatic contrast enhancement process for …

Error Estimation For An Integrated Gps/Ins System Using Adaptive Neuro-Fuzzy Technique, Salam A., Ahmed M. Hassan, Ali F. Lutfy

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Global Positioning System (GPS) and Strap down Inertial Navigation System (SDINS) can be Integrated Together To Provide A Reliable Navigation System. In This Paper, A Technique For Error Estimation In A GPS/INS System Based On A Low-Cost Inertial Measurement Unit (IMU) Is Offered. This Technique Is Composed Of Wavelet Transform (WT) And Adaptive Fuzzy System (AFS). The Wavelet Decomposition Is Used To De-Noise The Position And Velocity Components Of The GPS And INS Outputs. An AFS Is Introduced In This Paper To Estimate The Position And Velocity Errors In The Integrated System In Order To Provide Accurate Navigation Information About …

A Lab View Based Data Acquisition System For Radial Temperature Distribution, Ahmed Mudher, Hazem I. Ali, Ali Farooq Lutfi

Iraqi Journal of Computers, Communications, Control and Systems Engineering

Lab VIEW (Laboratory Virtual Instrument Engineering Workbench) is gaining its popularity as a graphical programming language especially for data acquisition and measurement. This is due to the vast array of data acquisition cards and measurement systems which can be supported by LabVIEW as well as the relative ease by which advanced software can be programmed. One area of application of LabVEW is in the measuring and analyzing of radial temperature distribution. This paper describes a LabVIEW based data acquisition and analysis developed specifically for radial temperature distribution. The temperature is simultaneously measured and displayed.

Synthesis And Characterization Of Metallic, Core-Shell And Composite Nanoparticles, Amar Kumbhar

All Dissertations

ABSTRACT
Silver nanoparticles exhibit size, shape and the surrounding dielectric medium dependent optical properties (scattering and absorption) in the visible spectral region. These optical properties can be explained in terms of the collective oscillation of the 'free conduction band electrons' or 'surface plasmons' induced by an external electromagnetic field. Dipole and Quadrupole Plasmon resonances have been observed for silver particles less than 100nm in diameter prepared using various synthetic techniques. However higher order resonances have been elusive due to lack of experimental techniques to prepare colloidal solutions of large silver nanoparticles in the size range above 100nm. Controlled hydrogen reduction …

Efficient Analysis Of Loaded Cylindrical Monopole Antennas, Adam Schreiber

All Dissertations

In this dissertation is presented a collection of papers focusing on enhancing the efficiency of integral equation solutions of antennas. A method of incorporating network principles into the method of moments is developed. Scattering parameters are determined for two structures: a coaxial-guide/radial-guide junction present in coaxial feeds of monopole and dipole antennas, and a folded coaxial guide junction proposed as part of an inductive load below the feed of the antenna. There is excellent agreement among the data obtained from the proposed method, independent MoM solutions not incorporating network principles, and measurements. An investigation into electrically switching a folded coaxial …