Digital Commons Network^™

The Murray Ledger And Times, January 7, 2009, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Alterations In Gene Expression And Sensitivity To Genotoxic Stress Following Hdmx Or Hdm2 Knockdown In Human Tumor Cells Harboring Wild-Type P53, Katherine Heminger, Michael Markey, Meldrick Mpagi, Steven J. Berberich

Educator Preparation & Leadership Faculty Works

While half of all human tumors possess p53 mutations, inactivation of wild-type p53 can also occur through a variety of mechanisms that do not involve p53 gene mutation or deletion. Our laboratory has been interested in tumor cells possessing wild-type p53 protein and elevated levels of HdmX and/or Hdm2, two critical negative regulators of p53 function. In this study we utilized RNAi to knockdown HdmX or Hdm2 in MCF7 human breast cancer cells, which harbor wild-type p53 and elevated levels of HdmX and Hdm2 then examined gene expression changes and effects on cell growth. Cell cycle and growth assays confirmed …

Monte Carlo Fast Dose Calculator For Proton Radiotherapy: Application To A Voxelized Geometry Representing A Patient With Prostate Cancer, Pablo Yepes, Sharmalee Randeniya, Phillip J. Taddei, Wayne D. Newhauser

Faculty Publications

The Monte Carlo method is used to provide accurate dose estimates in proton radiation therapy research. While it is more accurate than commonly used analytical dose calculations, it is computationally intense. The aim of this work was to characterize for a clinical setup the fast dose calculator (FDC), a Monte Carlo track-repeating algorithm based on GEANT4. FDC was developed to increase computation speed without diminishing dosimetric accuracy. The algorithm used a database of proton trajectories in water to calculate the dose of protons in heterogeneous media. The extrapolation from water to 41 materials was achieved by scaling the proton range …

Volume 46, Number 20: January 07, 2009, University Of North Dakota

University Letter Archive

No abstract provided.

Beyond Borders: An Ecosystem Approach To Environmental Regulation, Louis Van Gorder

Roger Williams University Law Review

No abstract provided.

The Sleeping Brain's Influence On Verbal Memory: Boosting Resistance To Interference, Jeffrey M. Ellenbogen, Justin C. Hulbert, Ying Jiang, Robert Stickgold

Dartmouth Scholarship

Memories evolve. After learning something new, the brain initiates a complex set of post-learning processing that facilitates recall (i.e., consolidation). Evidence points to sleep as one of the determinants of that change. But whenever a behavioral study of episodic memory shows a benefit of sleep, critics assert that sleep only leads to a temporary shelter from the damaging effects of interference that would otherwise accrue during wakefulness. To evaluate the potentially active role of sleep for verbal memory, we compared memory recall after sleep, with and without interference before testing. We demonstrated that recall performance for verbal memory was greater …

Flux Balance Analysis Of Primary Metabolism In Chlamydomonas Reinhardtii, Nanette R. Boyle, John A. Morgan

School of Chemical Engineering Faculty Publications

Background

Photosynthetic organisms convert atmospheric carbon dioxide into numerous metabolites along the pathways to make new biomass. Aquatic photosynthetic organisms, which fix almost half of global inorganic carbon, have great potential: as a carbon dioxide fixation method, for the economical production of chemicals, or as a source for lipids and starch which can then be converted to biofuels. To harness this potential through metabolic engineering and to maximize production, a more thorough understanding of photosynthetic metabolism must first be achieved. A model algal species, C. reinhardtii, was chosen and the metabolic network reconstructed. Intracellular fluxes were then calculated using …

Central Florida Future, Vol. 41 No. 2, January 7, 2009

Central Florida Future

Arts Complex II to begin construction; Bromance is in the air; Bromance; Hitt's goal: a diverse campus; Strange start date planned two years ago.

Further Studies Investigating The Behavioral Responses Of African Penguins (Spheniscus Demersus) To Olfactory Stimuli, Gregory B. Cunningham, Venessa Strauss

Biology Faculty/Staff Publications

Most of the research into seabird olfaction has focused on procellariiforms (albatrosses and petrels); these birds are responsive to food, nest and social odors. Recently, however, we demonstrated that wild and captive African penguins (Spheniscus demersus) could detect and orient towards a food-related odor, dimethyl sulfide (DMS). Since DMS is associated with high levels of primary productivity in the ocean, we postulated that penguins could use DMS as an indicator of regions where prey is likely to be found when diving. To continue to investigate how penguins use odors while foraging, we were interested in determining whether birds …

Evolution Of The Toxoglossa Venom Apparatus As Inferred By Molecular Phylogeny Of The Terebridae, Mandë Holford, Nicolas Puillandre, Yves Terryn, Corinne Cruaud, Baldomero Olivera, Philippe Bouchet

Publications and Research

Toxoglossate marine gastropods, traditionally assigned to the families Conidae, Terebridae, and Turridae, are one of the most populous animal groups that use venom to capture their prey. These marine animals are generally characterized by a venom apparatus that consists of a muscular venom bulb and a tubular venom gland. The toxoglossan radula, often compared with a hypodermic needle for its use as a conduit to inject toxins into prey, is considered a major anatomical breakthrough that assisted in the successful initial radiation of these animals in the Cretaceous and early Tertiary. The pharmacological success of toxins from cone snails has …

Parallel Shifts In Ecology And Natural Selection In An Island Lizard, Ryan Calsbeek, Wolfgang Buermann, Thomas B. Smith

Dartmouth Scholarship

Natural selection is a potent evolutionary force that shapes phenotypic variation to match ecological conditions. However, we know little about the year-to-year consistency of selection, or how inter-annual variation in ecology shapes adaptive landscapes and ultimately adaptive radiations. Here we combine remote sensing data, field experiments, and a four-year study of natural selection to show that changes in vegetation structure associated with a severe drought altered both habitat use and natural selection in the brown anole, Anolis sagrei.

Results: In natural populations, lizards increased their use of vegetation in wet years and this was correlated with selection on limb length …

Brave New Circuit: Creeping Towards Dna Database Dystopia In U.S. V. Weikert , Alec Rice

Roger Williams University Law Review

No abstract provided.

Mustang Daily, January 6, 2009

Cal Poly Student Newspaper

Student newspaper of California Polytechnic State University, San Luis Obispo, CA.

Parts Of The Whole: Is Everything Equally Important?, Dorothy Wallace

Numeracy

Two strategies are proposed for sorting out priorities and goals in education. At the college level the column argues that goals, and therefore requirements, should be set based on the desired knowledge base of the entire population rather than the individual. At the scale of a single K-12 classroom the column argues that priority be given to content requiring most instructor intervention, describing how the structure of class time and school activities would change as a result. Implementation of these strategies would lead to more efficient use of teacher’s time and effort, better allocation of systemic resources, and clarity of …

Quantitative Literacy On The Web Of Science, 2 – Mining The Health Numeracy Literature For Assessment Items, H L. Vacher, Todd Chavez

Numeracy

A topic search of the Web of Science (WoS) database using the term “numeracy” produced a bibliography of 293 articles, reviews and editorial commentaries (Oct 2008). The citation graph of the bibliography clearly identifies five benchmark papers (1995-2001), four of which developed numeracy assessment instruments. Starting with the 80 papers that cite these benchmarks, we identified a set of 25 papers (1995-2008) in which the medical research community reports the development and/or application of health-numeracy assessments. In all we found 10 assessment instruments from which we have compiled a total of 48 assessment items. There are both general and context-specific …

The Case For Infusing Quantitative Literacy Into Introductory Geoscience Courses, Jennifer M. Wenner, Eric M. Baer, Cathryn A. Manduca, R. Heather Macdonald, Samuel Patterson, Mary Savina

Numeracy

We present the case for introductory geoscience courses as model venues for increasing the quantitative literacy (QL) of large numbers of the college-educated population. The geosciences provide meaningful context for a number of fundamental mathematical concepts that are revisited several times in a single course. Using some best practices from the mathematics education community surrounding problem solving, calculus reform, pre-college mathematics and five geoscience/math workshops, geoscience and mathematics faculty have identified five pedagogical ideas to increase the QL of the students who populate introductory geoscience courses. These five ideas include techniques such as: place mathematical concepts in context, use multiple …

Establishing The Quantitative Thinking Program At Macalester, David Bressoud

Numeracy

In November 2005, the faculty of Macalester College voted to institute a graduation requirement in Quantitative Thinking (QT) that is truly interdisciplinary. It currently draws on courses from thirteen departments including Anthropology, Economics, Geography, Political Science, Theater, Mathematics, Environmental Science, and Geology. This article describes the process that led to the creation of this program. It explains how we were able to get broad buy-in at the beginning and the long process of trial and error—informed by formative assessment—that was needed to refine the initial vision and shape it into a viable program that would be accepted by most of …

All The More Reason For Qr Across The Curriculum, Bernard L. Madison

Numeracy

No abstract provided.

A Hidden Markov Random Field Model For Genome-Wide Association Studies, Hongzhe Li, Zhi Wei, J M. Maris

UPenn Biostatistics Working Papers

Genome-wide association studies (GWAS) are increasingly utilized for identifying novel susceptible genetic variants for complex traits, but there is little consensus on analysis methods for such data. Most commonly used methods include single SNP analysis or haplotype analysis with Bonferroni correction for multiple comparisons. Since the SNPs in typical GWAS are often in linkage disequilibrium (LD), at least locally, Bonferonni correction of multiple comparisons often leads to conservative error control and therefore lower statistical power. In this paper, we propose a hidden Markov random field model (HMRF) for GWAS analysis based on a weighted LD graph built from the prior …

Faculty Senate Monthly Packet January 2009, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The January 2009 Monthly packet includes the January agenda and appendices and the Faculty Senate minutes and attachments from the meeting held January 2009

John Mcmasters’Contributions To Aircraft Design Education, Russell M. Cummings

Aerospace Engineering

John McMasters was intensely interested in two seemingly diverse pursuits: aircraft design and technical work force development. The later pursuit often got John involved in encouraging the development and improvement of engineering education, especially aircraft design education. He spent countless hours considering the issues that contribute to good design education, and was a strong proponent of programs that would encourage students to become interested in design. An overview of John’s ideas on aircraft design education will be presented based on discussions with John, as well as papers that we co-authored. In addition, John had a long talk with me just …

Faculty Senate Meeting Agenda And Minutes, January 5, 2009

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on, January 5, 2009.

Faculty Senate Agenda, January 5, 2009, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Council on Teacher Education
• Scholarship Advisory Board
• EPC Items
• Code Review Committee
• PRPC – Proposal to amend Sections 402.11.1 and 402.12.6(2 & 8)
• Elimination of Distance & Electronic Education Subcommittee
• Grievance Policies – Definition of Days (policy 407.1.2) first reading remove from tab

Severity Of Root Rot In Mature Subterranean Clover And Associated Fungal Pathogens In The Wheatbelt Of Western Australia, Tim Scanlon, Tiernan A. O’Rourke, Martin J. Barbetti, Megan H. Ryan, Len J. Wade, Alan C. Mckay, Ian T. Riley, Hua Li, Krishnapillai Sivasithamparam

Journal articles

Pasture decline is considered to be a serious challenge to agricultural productivity of subterranean clover across southern Australia. Root disease is a significant contributing factor to pasture decline. However, root disease assessments are generally carried out in the early part of the growing season and in areas predominantly sown to permanent pastures. For this reason, in spring 2004, a survey was undertaken to determine the severity of root disease in mature subterranean clover plants in pastures located in the wheatbelt of Western Australia. DNA-based soil assays were used to estimate population density in the soil of a variety of soil-borne …

Central Florida Future, Vol. 41 No. 1, January 5, 2009

Central Florida Future

Alumnus drowns after kayak flips; Away from home; Love across the miles; Students learn through serving; Online courses on the rise; Online@UCF.

Recruitment In Child Psychiatry: The Impact Of A Voluntary Fellowship Program On Medical Students Career Decisions, Eric Arzubi

Yale Medicine Thesis Digital Library

This study was designed to measure interest in child and adolescent psychiatry among medical students and to assess the impact of an innovative medical student fellowship program on that interest. Students (N = 916) from ten medical schools completed an online survey designed to measure their interest in child and adolescent psychiatry and their understanding of the subspecialty. Students (N = 123) participating in a voluntary child and adolescent psychiatry fellowship offered at six of the ten medical schools completed an online survey designed to evaluate the quality of their experience and to measure the impact of the fellowship program …

Grapes Of Wrath? How The United States Can Reduce The Negative Effects Of Winery Wastewater, Kristen Cunningham

Colorado Environmental Law Journal

No abstract provided.

Hepatitis B Virus Subgenotypes D1 And D3 Are Prevalent In Pakistan, Anwar Ali Siddiqui, Saeeda Baig, Runu Chakravarty Runu Chakravarty, Tariq Moatter

Department of Biological & Biomedical Sciences

Background:

As the hepatitis B genotyping is important for assessing its clinical implications and geographical distribution, the sub-genotypes have been found useful for determination of specific genomic markers related to hepatocarcinogenesis. In Pakistan, there is no reported data on molecular evolutionary analysis of HBV. A study was, therefore, much needed to evaluate the spectra of mutations present in the strains prevalent here.

Findings:

To confirm specificity of PCR typing, phylogenetic analysis of the pre-S1 region and the divergence was studied through 13 sequences of 362 bp (accession number EF432765 – EF432777). A total of 315 serum samples, selected from HBsAg …

Wound Healing Plants Of Jalgaon District Of Maharashtra State, India, M. Z. Chopda, R. T. Mahajan

Ethnobotanical Leaflets

Jalgaon District of Maharashtra state (India) has a great heritage and rich in various green and semi evergreen species. Record of 3347 species from 201 families appeared in earlier literature from Jalgaon District. A list of 283 wound healing plants of Indian origin is compiled; out of these 224 plants are native of Maharashtra, a 131 plants among them occurred in Jalgaon District, which are in practice by local herbalist, Vaidyas and nonregistered medical practitioners and Mukhiya (Head) of tribal community. Taxonomical distribution showed 93.63% dicot and 6.37% monocot and a single aquatic plant. The investigation revealed that wound healing …

Measurement Of Ethnic Knowledge Associated With Semecarpus Anacardium L. F. -- A Rare And Endangered Ethnobotanical Plant Of Jharkhand, India, Kaushal Kumar

Ethnobotanical Leaflets

During the observation on ethnobotanical wealth used by the tribal people in their day to day needs, healthcare and socio-religious ceremonies of Jharkhand state of India, it was observed that due to the depletion of plants, the ethnic culture and associated knowledge system related with the plant species is also being lost. It has also seriously affected the oral traditions and knowledge of the tribal communities. To assess the above problem several indices like ‘Knowledge frequency’, ‘Plant-lore Index’ and percentage of ‘Community knowledge loss’ were developed to measure the knowledge status of tribes associated with Semecarpus anacardium L.f .