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Montana Kaimin, February 12, 2009, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

The George-Anne, Georgia Southern University

The George-Anne

• Ayers Weighs in on Controversial Cancelation
• Briefs
• Thru Our Lens
• News
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Illinois State University Report, February 12, 2009, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

Feb. 11, 2009 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Efficient Evaluation Of Ranking Procedures When The Number Of Units Is Large With Application To Snp Identification, Thomas A. Louis, Ingo Ruczinski

Johns Hopkins University, Dept. of Biostatistics Working Papers

Simulation-based assessment is a popular and frequently necessary approach to evaluation of statistical procedures. Sometimes overlooked is the ability to take advantage of underlying mathematical relations and we focus on this aspect. We show how to take advantage of large-sample theory when conducting a simulation using the analysis of genomic data as a motivating example. The approach uses convergence results to provide an approximation to smaller-sample results, results that are available only by simulation. We consider evaluating and comparing a variety of ranking-based methods for identifying the most highly associated SNPs in a genome-wide association study, derive integral equation representations …

Spartan Daily, February 11, 2009, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 132, Issue 10

The Cord Weekly (February 11, 2009)

The Cord

No abstract provided.

Stony Brook Press, V. 30, N. 08, Stony Brook University. Stony Brook Press.

Stony Brook Press

v. 30, n. 08, v.:ill. ; 38 cm (original analog pub.)

Newscope - February 11, 2009

Newscope

No abstract provided.

Dna Instability In Replicating Huntington's Disease Lymphoblasts, Milena Cannella, Vittorio Maglione, Tiziana Martino, Giuseppe Ragona, Luigi Frati, Guo-Min Li, Ferdinando Squitieri

Toxicology and Cancer Biology Faculty Publications

BACKGROUND: The expanded CAG repeat in the Huntington's disease (HD) gene may display tissue-specific variability (e.g. triplet mosaicism) in repeat length, the longest mutations involving mitotic (germ and glial cells) and postmitotic (neurons) cells. What contributes to the triplet mutability underlying the development of HD nevertheless remains unknown. We investigated whether, besides the increased DNA instability documented in postmitotic neurons, possible environmental and genetic mechanisms, related to cell replication, may concur to determine CAG repeat mutability. To test this hypothesis we used, as a model, cultured HD patients' lymphoblasts with various CAG repeat lengths.

RESULTS: Although most lymphoblastoid cell lines …

College Voice Vol. 33 No. 12, Connecticut College.

2008-2009

No abstract provided.

Trustees Approve Creation Of Uab Center For Cardiovascular Biology, Staff

Browse All News

No abstract provided.

Central Florida Future, Vol. 41 No. 16, February 11, 2009

Central Florida Future

SGA elections invisible to some; Working hard for the money; Lectures focuses on Holocaust women; Alarm security outsourced.

Quantitative And Fingerprint Analyses Of Chinese Sweet Tea Plant (Rubus Suavissimus S. Lee), Guixin Chou, Shun Jun Xu, Dong Liu, Yee Koh Gar, Jian Zhang, Zhijun Liu

Faculty Publications

The quality of botanical food is increasingly assessed by the content of multiple bioactive compounds. This study reports, for the first time, an HPLC fingerprinting method for the quality evaluation of Rubus suavissimus leaves possessing multiple bioactivities. Five constituents, gallic acid, rutin, ellagic acid, rubusoside, and steviol monoside, were quantified and used in developing qualitative chromatographic fingerprints. The limits of detection and quantification ranged from 0.29 to 37.86 μg/mL. The relative standard deviations (RSDs) of intra- and interday precisions were no more than 3.14 and 3.01%, respectively. The average recoveries were between 93.1 and 97.5%. The developed method was validated …

Volume 46, Number 25: February 11, 2009, University Of North Dakota

University Letter Archive

No abstract provided.

The Lumberjack, February 11, 2009

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Daily Eastern News: February 11, 2009, Eastern Illinois University

February

No abstract provided.

The Colby Echo (2009-02-11), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

February 11, 2009 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Role Of Rock And Pkc In Regulation Of Contraction Of Permeabilized Femoral Arterial Smooth Muscle, Brendan Browne

Theses and Dissertations

KCl is traditionally used as a stimulus to examine the role of increases in cytosolic Ca2+ on the regulation of smooth muscle contraction. KCl bypasses GPCR activation, thereby avoiding activation of additional cell signaling systems, such as phospholipase C and PKC that are inherent to Gaq and Ga12/13 stimulation. GPCR activation causes Ca2+ sensitization (greater force for a given increase in Ca2+) by a ROCK- and PKC-dependent inhibition of myosin light chain (MLC) phosphatase. Recent studies have demonstrated that KCl can also produce Ca2+ sensitization, implying that Ca2+ itself may induce Ca2+ sensitization. To test the hypothesis that Ca2+ can …

Survival Analysis With High-Dimensional Covariates: An Application In Microarray Studies, David Engler, Yi Li

Faculty Publications

Use of microarray technology often leads to high-dimensional and low-sample size (HDLSS) data settings. A variety of approaches have been proposed for variable selection in this context. However, only a small number of these have been adapted for time-to-event data where censoring is present. Among standard variable selection methods shown both to have good predictive accuracy and to be computationally efficient is the elastic net penalization approach. In this paper, adaptations of the elastic net approach are presented for variable selection both under the Cox proportional hazards model and under an accelerated failure time (AFT) model. Assessment of the two …

Measures To Summarize And Compare The Predictive Capacity Of Markers, Wen Gu, Margaret Pepe

UW Biostatistics Working Paper Series

The predictive capacity of a marker in a population can be described using the population distribution of risk (Huang et al., 2007; Pepe et al., 2008a; Stern, 2008). Virtually all standard statistical summaries of predictability and discrimination can be derived from it (Gail and Pfeiffer, 2005). The goal of this paper is to develop methods for making inference about risk prediction markers using summary measures derived from the risk distribution. We describe some new clinically motivated summary measures and give new interpretations to some existing statistical measures. Methods for estimating these summary measures are described along with distribution theory that …

February 10, 2009, University Of Mississippi. Faculty Senate

Meeting Minutes

Minutes for the February 10, 2009 meeting of the University of Mississippi Faculty Senate.

02-10-09 (The Liberty Champion, Volume 26, Issue 15)

2008 -- 2009

No abstract provided.

Spartan Daily, February 10, 2009, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 132, Issue 9

The Current Volume 19: Issue 18, Nova Southeastern University

Student Newspapers

No abstract provided.

Hotline Press Newspaper- Feb 10,2009 Vol 26 No 34, Hotline Press Newspaper

Hotline Press Newspaper 2009

No abstract provided.

Biosynthesis Of The Caenorhabditis Elegans Dauer Pheromone, Rebecca A. Butcher, Justin R. Ragains, Weiqing Li, Gary Ruvkun, Jon Clardy, Yi Mak Ho

Faculty Publications

To sense its population density and to trigger entry into the stress-resistant dauer larval stage, Caenorhabditis elegans uses the dauer pheromone, which consists of ascaroside derivatives with short, fatty acid-like side chains. Although the dauer pheromone has been studied for 25 years, its biosynthesis is completely uncharacterized. The daf-22 mutant is the only known mutant defective in dauer pheromone production. Here, we show that daf-22 encodes a homolog of human sterol carrier protein SCPx, which catalyzes the final step in peroxisomal fatty acid β-oxidation. We also show that dhs-28, which encodes a homolog of the human D-bifunctional protein that acts …

Cancer Treatment Using C-Type Natriuretic Peptides, David L. Vesely

USF Patents

The present invention includes a method of utilizing four peptide hormones to inhibit the growth of cancer(s). A dramatic decrease in the number of human pancreatic adenocarcinoma cells (i.e., the type of cancer with the highest mortality, with patients only surviving four months) was observed responsive to treatment. The application of the invention would be to utilize one or more of these peptide hormones alone and/or in combination to treat cancer. The ability of these peptide hormones to decrease the number of adenocarcinoma cells has implications for adenocarcinomas at other sites in the body with the majority of cancers of …

Academic Senate - Agenda, 2/10/2009, Academic Senate

Academic Senate Agendas

No abstract provided.