Digital Commons Network^™

Role Of Endothelin 1 In Follicular And Luteal Function In The Sheep, Fernando P. Perea-Ganchou

Graduate Theses, Dissertations, and Problem Reports (ETD)

Three experiments were carried out in order to examine the role of endothelin in follicular steroid secretion in vitro and in spontaneous and PGF2alpha-induced luteolysis in sheep.;In experiment 1, it was hypothesized that endothelin 1 (END1) acting through its receptors ENDRA and/or ENDRB, on granulosal cells of ovine preovulatory follicles would inhibit steroid production, and therefore, prevent the premature luteinization of granulosal cells of those follicles. Data from estrogen-inactive 20 follicles collected from 13 ewes were analyzed. Accumulation of E 2 and P4 by cultured granulosal cells was not affected by either LH or END1 or the END receptor blockers. …

Didox Modulates Reactive Oxygen Species Production And Inflammatory Events Induced By Lipopolysaccharide (Lps) And Aryl Hydrocarbon Receptor (Ahr) Ligands In Raw 264.7 Murine Macrophages., Thabe Matsebatlela

All Dissertations

Aberrant activation of macrophages during inflammation results in oxidative burst release of reactive oxygen and reactive nitrogen species (ROS/RNS) which are widely accepted to participate in pathogenesis of cancer, cardiovascular disease, atherosclerosis, hypertension, ischemia/reperfusion injury, diabetes mellitus, neurodegenerative diseases (Alzheimer's disease and Parkinson's disease), rheumatoid arthritis, and ageing. It is demonstrated here that Didox (3,4-Dihydroxybenzohydroxamic acid) possesses antioxidative and anti-inflammatory properties that can protect against inflammation and oxidative stress induced by lipopolysaccharide (LPS) and aryl hydrocarbon receptor (AHR) ligands (PCB126, E804, and IO) in Raw 264.7 murine macrophages. In brief, it is demonstrated here that Didox inhibits LPS-induced oxidative stress, …

Prospective Primary School Teachers’ Perceptions On Boiling And Freezing, Erdal Senocak

Australian Journal of Teacher Education

The aim of this study was to investigate the perceptions of prospective primary school teachers on the physical state of water during the processes of boiling and freezing. There were three stages in the investigation: First, open-ended questions concerning the boiling and freezing of water were given to two groups of prospective primary school teachers (Group-A had science background; Group-B had non-science background). Second, the participants’ answers were examined and analyzed. Finally, those participants who had misunderstandings were given semi-structured interviews to have a deeper insight into their perceptions. The results showed that the participants in Group-B held more misunderstandings …

Understanding The Antioxidant Mechanism Of Inorganic Selenium, Oxo- Sulfur, And Polyphenol Compounds, And The Biological Implications Of Functionalized Nanoparticles, Ria Ramoutar

All Dissertations

Inorganic selenium, oxo-sulfur, and polyphenol compounds are found in foods and dietary supplements, and are recognized for their nutritional benefits and their potential to treat or prevent diseases caused by oxidative stress. In our experiments to determine the effects of inorganic selenium compounds on iron-mediated DNA damage, Na₂SeO₃3 and SeO₂ exhibit antioxidant and pro-oxidant activities depending on concentrations of both the compound and hydrogen peroxide. Additional experiments demonstrate that iron coordination is a novel mechanism responsible for the observed activities. In similar experiments, oxo-sulfur compounds prevent Cu+/ H₂O₂-mediated DNA damage significantly …

Therapeutic Benefits Of Nature Images On Health, Ellen Vincent

All Dissertations

This thesis is a journey that travels back in time, when nature and health were inseparable, and forward to a time when science was the impetus for separation between the natural landscape and healing (chapter two), then into the present when nature and health are being reunited, only through science (chapter three).
The research conducted in 2008-2009 is reported in the form of three journal articles. The first article (chapter four) developed a methodology using sequential methods to select the nature images that would be used in the experiment. Appleton's prospect refuge theory was the basis for four image categories. …

Development Of Improved Torsional Potentials In Classical Force Field Models Of Poly (Lactic Acid), James Mcaliley

All Dissertations

In this work, existing force field descriptions of poly (lactic acid), or PLA, were improved by modifying the torsional potential energy terms to more accurately model the bond rotational behavior of PLA. Extensive calculations were carried out using density functional theory (DFT), for small PLA molecules in vacuo, and also using DFT with a continuum model to approximate the electronic structure of PLA in its condensed phase. From these results, improved force field parameters were developed using a combination of the OPLS and CHARMM force fields. The new force field, PLAFF2, is an update to the previously developed PLAFF model …

Effects Of Polyunsaturated Fatty Acids On Multidrug Resistance And Dna Methylation In Human Cancer Cell Lines, Cheng-Yi Kuan

All Dissertations

Accumulating evidences indicate that dietary intake of long-chain polyunsaturated fatty acids (PUFAs) can affect various cellular processes and improve response of cancer cells to chemotherapy. The mechanisms by which PUFAs affect this response are not well understood. P-glycoprotein (P-gp), encoded by the multidrug resistance gene MDR1, is a drug efflux transporter that plays an important role in the bioavailability of anti-cancer drugs. Effects of long-chain polyunsaturated fatty acids on MDR1 gene expression and functional activity in the human colon cancer cell line Caco-2 were studied in this research. Caco-2 cells were treated with different concentrations of three PUFAs: eicosapentaenoic acid …

Effect Of Cosb3 Nanoparticles On The Thermoelectric Properties Of Filled And Unfilled Cosb3 Skutterudites, Paola Alboni

All Dissertations

This study explores the possibility of somewhat decoupling the electrical and thermal conduction, thereby being able to limit the thermal conduction while minimizing the effect on the electrical conduction. The approach is using a nanoparticle layer with a slight compositional mismatch as compared to the bulk skutterudite. A hydrothermal nanoparticle-plating technique has been employed to grow a layer of CoSb₃ nanoparticles on the surface of skutterudite bulk matrix grains. Skutterudites of various forms were fabricated and studied in order to assess the effect of this nano-plated layer as a viable method in the improvement of thermoelectric properties of CoSb …

Population Ecology Of The Floodplain Herb Macbridea Caroliniana (Lamiaceae) With Investigations On The Species' Habitat, Breeding System And Genetic Diversity, Katherine Weeks

All Dissertations

The perennial herbaceous mint Macbridea caroliniana is known from 36 locations in discrete watersheds of the Carolinas and Georgia. It is one of relatively few conspicuously flowering herbs that occupy bottomland hardwood forests. The general project goal was to gain knowledge that is applicable to the species' conservation both at the Congaree National Park (CNP) where the largest known population of this species occurs and range-wide. Specific objectives were to (1) quantify the population size and describe the distribution of M. caroliniana within CNP, and determine the extent of co-occurrence with wild hogs and the non-native Murdannia keisak; (2) identify …

Kinetic Analysis Of Coal And Biomass Co-Gasification With Carbon Dioxide, Jiachuan Bu

Graduate Theses, Dissertations, and Problem Reports (ETD)

Based on Thermogravimetric Analysis (TGA) experimental data, a kinetic analysis of the Boudouard reaction was studied for three different coal chars, three different biomass chars, and their mixtures. The coal chars included: North Dakota Lignite, Illinois No.6, and Powder River Basin char; the biomass chars included: Hardwood, Switchgrass, and Corn Stove char. The reaction temperature ranged from 900°C to 1100°C. Different kinetic models were used for modeling the reaction rate. For the simplified Dutta and Wen model, it was found that the reaction rate was first order with respect to both CO2 and carbon. For the modified shrinking sphere model, …

Development Of Computational Tools For Modeling Engine Fuel Economy And Emissions, Christopher L. Marlowe

Graduate Theses, Dissertations, and Problem Reports (ETD)

The Integrated Bus Information System (IBIS) is a vehicle fleet emission and fuel economy prediction software. IBIS is under development by faculty and students of West Virginia University (WVU). The overall goal of IBIS is to provide an approachable and reliable method for users, primarily transit agencies, to evaluate overall fleet emissions and fuel consumption. This approach differs from current modeling packages as IBIS is an online tool and allows for a customizable, user-defined vehicle fleet.;The modeling strategy for IBIS involves creating models using data obtained from the WVU Center for Alternative Fuels, Engines, and Emissions (CAFEE) testing database. These …

Narrative Theory And Fort Berthold's Stories Of The Paranormal Or Supernatural, Waylon C. Baker

Theses and Dissertations

The author collected stories of the paranormal and supernatural from 10 enrolled members of the Three Affiliated Tribes of Fort Berthold, North Dakota. The research participants were members of the Mandan, Hidatsa, and Arikara tribes. Five research questions guided the study: (1) Where did these contemporary stories of the paranormal or supernatural originate? (2) What is the meaning behind these stories? (3) How are these stories different from other stories of the paranormal or supernatural? (4) Do the respondents “believe” in these stories of the paranormal? (5) Do these stories connect to traditional American Indian customs and beliefs?

The content …

Perceptions Of Weight Reduction Surgery: The Role Of Stigma And The Attribution Of Responsibility, Jessica Marie Behm

Theses and Dissertations

The amount of weight reduction surgeries performed in the United States has increased considerably within the last twenty years. Many people choose to undergo the procedure with the hopes of shedding the negative stigma of being obese and improving their life. The purpose of this study was to investigate how society views individuals who have elected to undergo weight reduction surgery. A questionnaire assessing the influence of three variables (Responsibility, Acceptability, and Stigma) on the perception of weight reduction surgery was developed and administered to 503 Midwestern college students. The respondents were presented with one of two vignettes depicting a …

Recent Applications Of Acyclic (Diene)Iron Complexes And (Dienyl)Iron Cations In Organic Synthesis, William A. Donaldson, Subhabrata Chaudhury

Chemistry Faculty Research and Publications

Complexation of (tricarbonyl)iron to an acyclic diene serves to protect the ligand against oxidation, reduction, and cycloaddition reactions, whereas the steric bulk of this adjunct serves to direct the approaches of reagents to unsaturated groups attached to the diene onto the face opposite to iron. Furthermore, the Fe(CO)₃ moiety can serve to stabilize carbocation centers adjacent to the diene (i.e. pentadienyl-iron cations). Recent applications of these reactivities to the synthesis of polyene-, cyclopropane-, cycloheptadiene-, and cyclohexenone-containing natural products or analogues are presented.

The Link, Vol 3, No. 8, August/September 2009, Illinois State University, Center For Integrated Professional Development

The Link

Newsletter for the Illinois State University Center for Integrated Professional Development

A Study Of The Impact Of High School Physical Education Curriculum Choices On Health-Related Fitness Indicators And Motivation For Physical Activity, Beverly J. Ziegler

Education Doctoral

Lack of physical activity and poor nutrition are factors that contribute to the obesity epidemic. Promotion and support of meaningful quality physical education experiences may be an appropriate focus to improve the health, fitness and wellness of students. The purpose of the research study is to determine if there is an impact in students in grades eleven and twelve physical education who receive choice vs. no choice on their health related fitness indicators and their motivation for physical activity. The research is grounded int eh Self-Determination Theory (SDT) of human motivation to determine if the social contexts (climate) in physical …

The Relationship Of Level Of Traumatic Exposure, Perceived Stress, And Resilience With Salivary Cortisol And Salivary Alpha-Amylase Diurnal Rhythm In Palestinian Children 10-12 Years Exposed To Chronic War Violence, Mohammad R. Asia Phd, Rn

Dissertations

Political violence, war, and genocide exist across the world and often the innocent children and civilians become victims. War and long-term violence have potentially harmful psychological and physiological effects on children. There are limited studies on the effect of prolonged armed conflict on the child's physiologic and psychologic stress responses. The purpose of this study is to investigate the relationships between level of trauma, stress and resilience with salivary cortisol and salivary alpha-amylase (sAA) diurnal patterns in Palestinian children, ages 10-12, living in a long standing war zone. Salivary cortisol, a surrogate marker of hypothalamic-pituitary-adrenal axis (HPA) activity, and salivary …

Psychometric Testing Of The Information-Motivation-Behavioral Skills Model Of Behavior Change Questionnaire In Mexican-Americans With Diabetes Type 2, Beverley Brownell Phd

Dissertations

Background: The most successful diabetes self-management (DSM) programs focus on changing previously established behavior patterns. To develop focused and culturally appropriate self-management programs, health care providers need valid and reliable assessment tools. Purpose: To test the reliability and content and construct validity of an instrument developed to assess diabetes knowledge, motivation, and adherence to medical regimes. The Information-Motivation-Behavioral (IMB) Skills Diabetes scale was tested with 83 Mexican-American adults with type 2 diabetes from a community in Orange County, CA. Methodology: A cross-sectional correlational study design was conducted with 64 female and 19 male Mexican-American adults diagnosed diabetes type 2 patients. …

Heterogeneity In Returns To Work Experience: A Dynamic Model Of Female Labor Force Participation, Ken Yamada

Research Collection School Of Economics

This paper provides structural estimates of heterogeneous returns to work experience for Japanese married women. A dynamic model of labor force participation is used to account for dynamic selfselection into employment. Heterogeneity is incorporated into the model in a way that allows for the multidimensional skill heterogeneity in employment and home production and for the individual-specific slope and curvature of experience effect on earnings. The structural estimates and their comparison to the reduced-form estimates highlight the importance of dynamic self-selection into employment and heterogeneity in returns to work experience.

Examining The Efficacy Of Parent -Child Interaction Therapy With High -Functioning Autism, Joshua J. Masse

Graduate Theses, Dissertations, and Problem Reports (ETD)

Externalizing behaviors are a common component of the clinical presentation of autism spectrum disorders (ASD) and are typically the initial focus of treatment for children within this population. Although a number of therapies targeting behaviors characteristic of ASD exist, most do not offer a short-term, manual-based approach aimed at increasing child compliance. Although traditionally used with typically-developing children, Parent-Child Interaction Therapy (PCIT) is one behaviorally-based, short-term (∼14 sessions) parent training program that has demonstrated success in increasing child compliance, reducing problem behavior, and improving parent-child communication. The study examined the efficacy of PCIT as a first-line treatment for children with …

The Interactions Of Cisplatin And Model Proteins Studied By Electrospray Ionization Mass Spectrometry And Tandem Mass Spectrometry, Ting Zhao

Graduate Theses, Dissertations, and Problem Reports (ETD)

Protein-cisplatin interactions lie at the heart of both the effectiveness of cisplatin as an anticancer drug and side effects associated with cisplatin treatment. A greater understanding of the protein-cisplatin interactions at the molecular level can not only improve our understanding of the action of cisplatin as an anticancer drug but also inform the design of cisplatin-like agents for future use. Therefore, the interactions of cisplatin with three different model proteins were studied, which may provide theoretical basis for predicating mechanistically relevant protein-cisplatin interactions in biological fluids.;Cytochrome c (cyt c) was used as a model protein to develop a mass spectrometric …

Vascular Plants Of South Fork Mountain, Humboldt & Trinity Counties, James P. Smith Jr

Botanical Studies

No abstract provided.

Nano-Surface Engineering On Copper Substrate For Friction Reduction, Julius Morehead

Mechanical Engineering Undergraduate Honors Theses

Nano-engineered-textures on a material surface used to conduct fluids can significantly improve the hydrophobicity or wetting property of the surface, resulting in lower resistance of the surface to the fluid?s movement. In this work, aluminum-induced crystallization of amorphous silicon was investigated for generating nano-textures on copper substrates, a common material in heating, ventilating, air conditioning, and refrigeration systems. Flat copper substrate was utilized. Several experiments were conducted to study the effects of annealing temperature, annealing duration, a-Si and Al thickness, and the sequence of film structure. Scanning electron microscopy was employed to characterize the surface nano-topography. The results showed that …

Nitrogen And Phosphorus Remediation Of Aquatic Garden Plants In Laboratory-Scale Constructed Wetlands., Robert Polomski

All Dissertations

This research investigated the potential of growing marketable aquatic garden plants that also remediate nursery and greenhouse runoff in a subsurface-flow constructed wetland. The cost of wastewater treatment is offset by the production of revenue-generating horticultural crops. Aquatic garden plants that offer the dual benefits of nutrient remediation and aesthetic value may also be planted in bioretention basins, rain gardens, buffer zones, and filter strips.
Fifteen commercially available aquatic garden plants were grown for 8 weeks in a laboratory scale subsurface wetland in a greenhouse and received nitrogen (N) and phosphorus (P) from Hoagland's nutrient solution every two days for …

Differential Mortality Drives Life-History Evolution And Population Dynamics In The Fish Brachyrhaphis Rhabdophora, Jerald B. Johnson, J. Jaime Zuniga-Vega

Faculty Publications

Life-history theory predicts that populations experiencing different levels of extrinsic mortality will evolve divergent reproductive strategies. Previous work in the live bearing fish Brachyrhaphis rhabdophora shows that individuals from populations that occur with piscivorous fish mature earlier and at smaller sizes and have more and smaller offspring than fish from populations without predators. However, until now, there have been no data to demonstrate that differences in mortality rates actually exist between predator and predator free sites. Here we present the results of a serial mark-recapture field study designed to estimate mortality rates in natural populations of B. rhabodophora from Costa …

Proton Irradiation Effects On Semiconductor Cdse/Zns Core/Shell Nanocrystals, Stephen Graham Charter

Graduate Theses and Dissertations

The absorbance and photoluminescence measurement of semiconductor CdSe/ZnS core shell nanocrystals were reviewed and investigated after they were exposed to proton irradiation. The CdSe/ZnS core shell nanocrystals of 3.2nm and 4.4nm were commercially purchased and investigated. These nanocrystals were embedded in UV resin. Proton irradiation of energy 2MeV was applied at doses from 3 x 1013 protons cm-2 to 1.47 x 1015 protons cm-2 for both nanocrystal sizes. Absorbance measurements were conducted at 300K. Results from absorbance measurements showed slight broadening of the first exciton peak of both samples but was most noticeable in the 3.2nm nanocrystal sample. UV resin …

Cloning And Expression Of A Putative Exported Protein Coding Gene Sas1089 From An Invasive Community Associated Staphylococcus Aureus Strain Mssa476, Nailah Alzaki

All-Inclusive List of Electronic Theses and Dissertations

Originally, methicillin resistant Staphylococcus aureus (MRSA) occurred primarily in the hospital setting and was designated hospital- associated MRSA (HA-MRSA). In recent years, isolates of Staphylococcus aureus from the community (CA-MRSA), found to be methicillin resistant, are not as resistant tooth~ antibiotics as HA-MRSA. However, community strains are noted for their invasiveness causing soft tissue infections with propensity for invasion to deeper sites.

Gpu-Based Implementation Of Real-Time System For Spiking Neural Networks, Dmitri Yudanov

Theses

Real-time simulations of biological neural networks (BNNs) provide a natural platform for applications in a variety of fields: data classification and pattern recognition, prediction and estimation, signal processing, control and robotics, prosthetics, neurological and neuroscientific modeling. BNNs possess inherently parallel architecture and operate in continuous signal domain. Spiking neural networks (SNNs) are type of BNNs with reduced signal dynamic range: communication between neurons occurs by means of time-stamped events (spikes). SNNs allow reduction of algorithmic complexity and communication data size at a price of little loss in accuracy. Simulation of SNNs using traditional sequential computer architectures results in significant time …

Earmstrong, Armstrong Atlantic State University

Armstrong News & Publications: e-Armstrong Newsletter (Archived)

No abstract provided.

The Helicobacter Pylori Anti-Sigma Factor Flgm Is Predominantly Cytoplasmic And Cooperates With The Flagellar Basal Body Protein Flha, Melanie Rust, Sophie Borchert, Eike Niehus, Sarah A. Gripp, Afrodita Bajceta, Jonathan L. Mcmurry, Sebastian Suerbaum, Kelly T. Hughes, Christine Josenhans

Faculty Articles

Helicobacter pylori requires flagellar motility and orientation to persist actively in its habitat. A particular feature of flagella in most Helicobacter species including H. pylori is a membraneous flagellar sheath. The anti-sigma factor FlgM of H. pylori is unusual, since it lacks an N-terminal domain present in other FlgM homologs, e.g., FlgM of Salmonella spp., whose regulatory function is intimately coupled to its secretion through the flagellar type III secretion system. The aim of the present study was to characterize the localization and secretion of the short H. pylori FlgM in the presence of a flagellar sheath and to elucidate …