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2009

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Pengaruh Bahasa Arab Dalam Pendalilan Hukum Syara : Tinjauan Pandangan Mujtahidin Dalam Kes Poligami / Asmilyia Mohd Mokhtar, Asmilyia Mohd Mokhtar Jan 2009

Pengaruh Bahasa Arab Dalam Pendalilan Hukum Syara : Tinjauan Pandangan Mujtahidin Dalam Kes Poligami / Asmilyia Mohd Mokhtar, Asmilyia Mohd Mokhtar

Student Works (2000-2009)

No abstract provided.


The Impact Of Advertising Message Strategies : Fear Appeal Versus Sex Appeal Upon Consumers' Intention To Purchase / Noorlin Azwin Binti Izahar, Noorlin Azwin Izahar Jan 2009

The Impact Of Advertising Message Strategies : Fear Appeal Versus Sex Appeal Upon Consumers' Intention To Purchase / Noorlin Azwin Binti Izahar, Noorlin Azwin Izahar

Student Works (2000-2009)

No abstract provided.


Biological Activities Of Selected Malaysian Seaweeds / Shuba A/P Salvam, Shuba Salvam Jan 2009

Biological Activities Of Selected Malaysian Seaweeds / Shuba A/P Salvam, Shuba Salvam

Student Works (2000-2009)

Antioxidant activity of nine seaweeds, two microalgae, two teas, two dried fruit skins and one dried flower were determined. Among the seaweeds extracts, Sargassum binderi showed the highest AOx (antioxidant activity) for its boiled water extract in both AEAC (ascorbic acid equivalence antioxidant capacity) and DPPH (Diphenyl-1-picrylhydrate) assays. Methanolic extracts of Sargassum binderi and Padina tetrastromatica showed the highest AOx in DPPH and AEAC assays respectively. Gracilaria changii showed the highest AOx for its methanolic extract in Galvinoxyl assay. Boiled water extract of Padina tetrastromatica showed the highest total phenolic content in Total Phenolic assay. The two microalgae tested were …


Synthesis, Characterization And Biological Activity Of Some Carbazone Schiff Bases And Their Metal Complexes / Mohd. Rizal Bin Razali, Mohd. Rizal Razali Jan 2009

Synthesis, Characterization And Biological Activity Of Some Carbazone Schiff Bases And Their Metal Complexes / Mohd. Rizal Bin Razali, Mohd. Rizal Razali

Student Works (2000-2009)

All the metal complexes in this study are synthesized by the general method which the ligand was first prepared by refluxing the precursors of the Schiff base. It was then followed by the addition of the appropriate metal salt to form metal complexes. The characterization of the series of the Schiff base complexes of Ni(II), Cu(II), Zn(II) and Cd(II) with ligand systems containing nitrogen, sulphur and oxygen donor atoms were also carried out. Formation of the Schiff base ligands were confirmed by the presence of v(C=N) band at the range 1550-1650 cm-1 in the IR spectra. In some cases the …


The Implementation Of Environmental Management System In Kamunting Industrial Zone : A Bio-Economic Approach / Huda Sameer Mohammed Rashad Almaarofi, Huda Sameer Mohammed Rashad Almaarofi Jan 2009

The Implementation Of Environmental Management System In Kamunting Industrial Zone : A Bio-Economic Approach / Huda Sameer Mohammed Rashad Almaarofi, Huda Sameer Mohammed Rashad Almaarofi

Student Works (2000-2009)

Environmental Management Practices has become an important key factor in overall business planning and activities nowadays. Environmental Management System (EMS) is one of the environmental management practices which can assist organizations to meet their increasingly heavy onus of responsibility for better condition of future world’s environment. Moreover, firms that adopted EMS have expertise in a wide range of benefits such as: cost saving benefits and a clear reduction in environmental/natural liability and calamity. Many studies have been carried out on investigating the benefits of the EMS, particularly for economy; however, none of these studies had shown any relation to a …


Micropropagation Of Pineapple (Ananas Comosus) Cv. Smooth Cayenne And Moris / Abdelhamid M. Hamad, Abdelhamid M. Hamad Jan 2009

Micropropagation Of Pineapple (Ananas Comosus) Cv. Smooth Cayenne And Moris / Abdelhamid M. Hamad, Abdelhamid M. Hamad

Student Works (2000-2009)

A total of 25 experiments were conducted to test the effect of several factors such as hormone types and concentrations, incubation periods, subcultures, medium states, sucrose, pH, explants size, explants density and medium volume per culture and medium strength on the shoot formation per explant, total shoots, total cost and cost per shoot of Smooth cayenne and Moris pineapple at each and over 4 consecutive subcultures. Rooting responses and plantlets quality of both cultivars were tested in different hormones, media strength, shoots age, sucrose content and incubation periods. Survival during acclimatization was evaluated in relation to rooting treatments, plantlet quality, …


Determination Of Palm Biodiesel/Petroleum Diesel Blend Ratio Through Spectroscopic Method / Alinda Samsuri, Alinda Samsuri Jan 2009

Determination Of Palm Biodiesel/Petroleum Diesel Blend Ratio Through Spectroscopic Method / Alinda Samsuri, Alinda Samsuri

Student Works (2000-2009)

Biodiesel, defined as the alkyl esters (usually methyl esters) of vegetable oils, is miscible with conventional petroleum diesel fuel at all blend levels. Blends of biodiesel with conventional petroleum diesel fuel represent a common utilization of biodiesel. The Malaysian Government has initiated the implementation of palm biodiesel since 2007 and the proposed blend is B5. Accordingly, there is interest and need for the development of methods for determining or verifying the blend level of biodiesel in petroleum diesel. To date, the most widely used and acceptable method for determination of biodiesel blend levels is using IR spectroscopy. The present study …


Comparative Molecular Subtyping Of Salmonella Enterica Serovar Typhi By Vntr, Rep-Pcr And Restricted Ap-Pcr / Sepideh Rezanejad Shirazi, Sepideh Rezanejad Shirazi Jan 2009

Comparative Molecular Subtyping Of Salmonella Enterica Serovar Typhi By Vntr, Rep-Pcr And Restricted Ap-Pcr / Sepideh Rezanejad Shirazi, Sepideh Rezanejad Shirazi

Student Works (2000-2009)

In this study, Salmonella enterica serovar Typhi (S. Typhi) strains collected from outbreak and sporadic cases of typhoid fever during the years 1998 to 2007 in Malaysia were characterized using three PCR-based methods, i.e., restricted arbitrarily primed PCR (resAP-PCR), repetitive element PCR (rep-PCR) and variable-number tandem repeat (VNTR) analysis. The objective of this study was to explore the utility of VNTR and resAP-PCR as newer molecular methods in comparison with the commonly used method of rep-PCR to subtype S. Typhi. ResAP-PCR analysis was conducted using arbitrary primers STHae8 and STAlu9 following endonuclease digestion of S. Typhi DNA with HaeIII and …


Effect Of Rna Interference On Myb Transcripts During Flower Development In Dendrobium Orchid / Jennifer Vincent, Jennifer Vincent Jan 2009

Effect Of Rna Interference On Myb Transcripts During Flower Development In Dendrobium Orchid / Jennifer Vincent, Jennifer Vincent

Student Works (2000-2009)

RNA interference is currently a widely used technique for gene silencing studies in several plant and animal systems. In this study a rapid and inexpensive RNAi technique was used for manipulation of endogenous gene expression in Dendrobium orchids using large quantities of dsRNA which were synthesized in HT115 E. coli. A partial cDNA clone of the MYB9 gene was isolated from Dendrobium Sonia flowers and this was confirmed by sequencing and local alignment analysis using BLAST. The MYB9 gene sequence was cloned into a bacterial expression vector in forward and reverse orientations and transformed into HT115 E. coli strain where …


Osteopromotive Effects Of Polyhydroxyalkanoates In An Animal Model / Shirley Koh Pui Ling, Shirley Pui Ling Koh Jan 2009

Osteopromotive Effects Of Polyhydroxyalkanoates In An Animal Model / Shirley Koh Pui Ling, Shirley Pui Ling Koh

Student Works (2000-2009)

The biocompatibility and potential osteoconductive properties of medium-chain-length polyhydroxyalkanoates (mcl-PHA) in bone was investigated using the rabbit mandible as the animal model. The PHA was produced by a bacteria Pseudomonas putida using saponified palm kernel oil (SPKO) as carbon source. Twelve New Zealand white rabbits weighing between 2.5 kg to 3.5 kg were used. Twenty four of full thickness critical size (15 mm × 10 mm) defects were created in rabbit mandibles bilaterally. In each rabbit, the PHA sheet of size 19 mm × 27 mm was wrapped over the defect on one side. The remaining defects were left empty …


Tissue Culture And Morphogenesis Of Begonia X Hiemalis Fotsch. Cv.Schwabenland Red / Asmah Awal, Asmah Awal Jan 2009

Tissue Culture And Morphogenesis Of Begonia X Hiemalis Fotsch. Cv.Schwabenland Red / Asmah Awal, Asmah Awal

Student Works (2000-2009)

In vitro regeneration of Begonia x hiemalis Fotsch. cv. Schwabenland Red, also known as Begonia Rose, an ornamental plant was achieved from four different intact explants; such as leaf, peduncle, petiole and stem explants. The sterilization protocol was established for in vivo explants to overcome contamination. The results revealed that four different types of explants could produce in vitro regeneration. Leaf and petiole explants were amongst the best explants that were observed in this study. The optimum regeneration medium was identified in this study, i.e. MS medium supplemented with 1.0 mg/l BAP and 1.0 mg/l NAA which produced normal shoots. …


Bioremediation Of Landfill Gas Under Laboratory Conditions / Navarani A/P Vejaratnam, Navarani Vejaratnam Jan 2009

Bioremediation Of Landfill Gas Under Laboratory Conditions / Navarani A/P Vejaratnam, Navarani Vejaratnam

Student Works (2000-2009)

Per capita generation of municipal solid waste (MSW) in Malaysia has reached 1.3kg per day giving a total generation of more than 31000 tonnes daily. All the MSW collected are disposed into 260 landfills or dumps with 90% of the landfills being non-sanitary. Due to lack of proper gas collection facilities, almost all the methane produced are released passively to the atmosphere.Malaysian landfills produce 1.3-7.5 L/kg/year of methane gas. Since methane is 23 times more harmful as greenhouse gas than CO2, it is essential to mitigate its emission from landfills. One option to reduce methane emissions is to oxidize the …


Identification And Comparison Of Orthologous Argonaute Gene Sequences In Bananas / Pui Han Pin, Han Pin Pui Jan 2009

Identification And Comparison Of Orthologous Argonaute Gene Sequences In Bananas / Pui Han Pin, Han Pin Pui

Student Works (2000-2009)

The Argonaute proteins are key components in the effector complex of RNA silencing pathways which interact with small RNAs to mediate sequence specific silencing of nucleic acid targets (reviewed in Carmell et al., 2002; Lingel & Izaurralde, 2004; Cerrutti & Casas-Mollano, 2006; Peters & Meister, 2007; Tolia & Joshua-Tor, 2007; Hutvagner & Simard, 2008). In plants, these proteins are involved in a diversity of biological roles such as antiviral defence, heterochromatin regulation and in the regulation of growth and development (reviewed in Carmell et al., 2002; Ding et al., 2004; Lippman & Martienssen, 2004; Bartel, 2004; Zaratiegui et al., 2007, …


Reactions Of Epoxidized Natural Rubber With Palm Oil-Based Alkyds And Medium-Chain-Lenght Polyhydroxyalkanoates / Lee Siang Yin, Siang Yin Lee Jan 2009

Reactions Of Epoxidized Natural Rubber With Palm Oil-Based Alkyds And Medium-Chain-Lenght Polyhydroxyalkanoates / Lee Siang Yin, Siang Yin Lee

Student Works (2000-2009)

Actinomycetes are widespread in marine ecosystem. They are of interest in research field as they are capable to produce bioactive secondary metabolites which can be developed into useful pharmaceutical products. An example of the product is antibiotics which can be used to treat infectious diseases. The potential of antibacterial and antifungal activity of eleven marine derived actinomycetes from the genus Streptomyces were studied. They were tested against bacteria Enterobacter faecalis, Staphylococcus aureus, Bacillus subtilis, Pleisiomonas shigelloides and Pseudomonas aeruginosa and fungi Candida parapsilosis and Candida albicans. Primary screening by the cross streak method and secondary screening by diffusion using paper …


Some Aspects Of Physico-Chemical Properties Of Chitosan In Solutions And Films / Elham S. Meftah Elgannoudi, Elham S. Meftah Elgannoudi Jan 2009

Some Aspects Of Physico-Chemical Properties Of Chitosan In Solutions And Films / Elham S. Meftah Elgannoudi, Elham S. Meftah Elgannoudi

Student Works (2000-2009)

This work is focused on studying the influence of temperature, concentration, shearing time and storage time on the rheological properties, i.e., the dynamic viscosity and shear stress as a function of shear rate of chitosan solubilized in the three selected solvents.Results showed that within the temperature range we studied (20oC to 50oC), apronounced shear thinning was observed. It was also found that all the solutions obeyed the Arrhenius equation. When the effect of concentration was studied, it was observed that the shear thinning behavior was more remarkable at the highest concentration (10 g L-1) for all solutions. The effect of …


Budaya Pemakanan Masyarakat Malaysia Dari Perspektif Agama, Polisi, Sains Dan Teknologi Dengan Rujukan Khusus Kepada Pengaruh Islam Dalam Penghasilan Makanan / Che Wan Jasimah Bt. Wan Mohamed Radzi, Che Wan Jasimah Wan Mohamed Radzi Jan 2009

Budaya Pemakanan Masyarakat Malaysia Dari Perspektif Agama, Polisi, Sains Dan Teknologi Dengan Rujukan Khusus Kepada Pengaruh Islam Dalam Penghasilan Makanan / Che Wan Jasimah Bt. Wan Mohamed Radzi, Che Wan Jasimah Wan Mohamed Radzi

Student Works (2000-2009)

Kajian yang merentasi pelbagai disiplin ilmu ini bertujuan untuk mengkaji budaya pemakanan masyarakat Malaysia daripada aspek budaya, dasar, sains, teknologi dan agama Islam. Hubungan di antara budaya dan makanan, sains dan teknologi dan makanan, kesihatan dan makanan, serta agama dan makanan dikaji dengan lebih mendalam. Antara persoalan yang dikaji ialah apakah makna budaya pemakanan itu sebenarnya dan bagaimanakah rupa bentuk corak pemakanan masyarakat hari ini setelah ia mengalami gelombang arus budaya pemakanan India, Cina, Islam dan moden. Kajian ini dibahagi kepada enam bab. Perbincangan di dalam bab pertama meliputi pengenalan, pernyataan masalah, objektif kajian, metodologi kajian, limitasi kajian serta semakan …


Assessment Of Water Quality Parameters, Biomaginfication Studies Of Selected Heavy Metals And Characterization Of Solid Wastes In Sungai Pencala / N. Lakshmi Praba, N. Lakshmi Praba Jan 2009

Assessment Of Water Quality Parameters, Biomaginfication Studies Of Selected Heavy Metals And Characterization Of Solid Wastes In Sungai Pencala / N. Lakshmi Praba, N. Lakshmi Praba

Student Works (2000-2009)

The study was conducted to assess the extent of pollution in Sungai Pencala. A total of 14 monitoring stations were established along the river. The selected sampling stations represented the various activities in the surroundings of Sungai Pencala. Samplings were conducted 12 times over a period of 16 months from March 2006 – June 2007. Water quality parameters such as temperature, pH, DO, BOD, COD, NH3-N, conductivity, tubidity, TSS, TDS, TBC, and E Coli were monitored to determine the pollution status of the river. The results were then compared to the current recommended Interim National Water Quality Standards for Malaysia …


Effects Of Environmental Education Through Camping Experience On Students’ Knowledge And Attitude Regarding Wetlands / Jaya Mary Asirvatham, Jaya Mary Asirvatham Jan 2009

Effects Of Environmental Education Through Camping Experience On Students’ Knowledge And Attitude Regarding Wetlands / Jaya Mary Asirvatham, Jaya Mary Asirvatham

Student Works (2000-2009)

The study was conducted to determine if environmental education camp has an effect on the level of knowledge and attitude regarding wetlands. The result of this study was based on a questionnaire survey of pre-test and post-test groups which consisted of 206 students, who attended the education camp. Participants of the camp were primary and secondary school students from 10 states which were segregated into Eastern, Northern and Southern zones of Peninsular Malaysia. The study examined the demographic profile, pre-camp knowledge and attitude of students regarding wetlands, students’ expectations and perception of the environmental education camp. Students’ pre-camp environmental knowledge …


Kajian Bioaktiviti Dan Kandungan Kimia Cassia Alata L. Dan Cassia Tora L. / Mastura Binti Abd. Malek, Mastura Abd. Malek Jan 2009

Kajian Bioaktiviti Dan Kandungan Kimia Cassia Alata L. Dan Cassia Tora L. / Mastura Binti Abd. Malek, Mastura Abd. Malek

Student Works (2000-2009)

Kajian telah dijalankan ke atas dua spesies tumbuhan ubatan iaitu Cassia alata L. dan Cassia tora L. untuk mengenalpasti kandungan kimia yang hadir dan bioaktivitinya. Penskrinan fitokimia terhadap ekstrak-ekstrak tumbuhan kajian menunjukkan kehadiran sebatian-sebatian seperti antrakuinon, terpenoid dan flavanoid. Aktiviti antimikrob oleh ekstrak tumbuhan kajian dikaji terhadap beberapa strain bakteria, yis dan kulat yang bersifat patogenik kepada manusia. Cassia alata L. dan Cassia tora L. menunjukkan aktiviti antimikrob yang kuat ke atas strain bakteria. Ujian antioksidan yang terdiri daripada tiga jenis asai iaitu asai pelupusan DPPH, asai pengurangan kuasa dan asai pelunturan β-karotena telah dijalankan untuk mengkaji aktiviti antioksidan ekstrak …


Synthesis, Characterization, And Photocatalytic Degradation Of Some Organotin Compounds / Mohammad Reza Reisi, Mohammad Reza Reisi Jan 2009

Synthesis, Characterization, And Photocatalytic Degradation Of Some Organotin Compounds / Mohammad Reza Reisi, Mohammad Reza Reisi

Student Works (2000-2009)

Organotin compounds (OTCs) are the compounds that have at least one C- Sn bond. Some of the organotin compounds are hazardous to the environment. This is particularly true for tributyltin chloride (TBTCl) which has been used as antifouling agent on painting of the ships. This compound caused hazardous problems for marine environment. In this work, photo-degradation of this compound in water was performed by ultraviolet irradiation, ultraviolet irradiation in the presence of TiO2 and ultraviolet irradiation in the presence of a mixture of TiO2 and polyoxometallate (POM). The rate of photo-degradation reaction of TBTCl was investigated and rate of reactions …


Teori Istihalah Menurut Perspektif Islam Dan Sains : Aplikasi Terhadap Beberapa Penghasilan Produk Makanan / Mohammad Aizat Bin Jamaludin, Mohammad Aizat Jamaludin Jan 2009

Teori Istihalah Menurut Perspektif Islam Dan Sains : Aplikasi Terhadap Beberapa Penghasilan Produk Makanan / Mohammad Aizat Bin Jamaludin, Mohammad Aizat Jamaludin

Student Works (2000-2009)

Kajian ini memfokuskan aplikasi teori Istihalah menurut perspektif Islam dan sains. Pada dasarnya, teori ini tidak distrukturkan dengan sistematik dalam khazanah perbendaharaan fiqh Islam. Manakala dalam perspektif sains tiada satu perbincangan khusus yang melibatkan Istihalah. Walaupun begitu, ia mempunyai konotasi yang hampir sinonim dengan teori perubahan zat. Kajian ini melibatkan aplikasi teori Istihalah terhadap beberapa penghasilan produk makanan. Untuk mencapai objektif yang ditetapkan, pengkaji telah menggunakan beberapa metode. Di antaranya ialah metode pengumpulan data yang merangkumi kajian perpustakaan dan kajian lapangan. Kajian perpustakaan diaplikasi untuk mendapatkan data-data primer dan sekunder khususnya sebagai landasan dan struktur teori Istihalah. Manakala dalam kajian …


Efl Learning Strategies Used By Female Undergraduate Students / Wafa Ismail Saud, Ismail Saud Wafa Jan 2009

Efl Learning Strategies Used By Female Undergraduate Students / Wafa Ismail Saud, Ismail Saud Wafa

Student Works (2000-2009)

The aim of the present study was to provide an accurate and holistic description of the language learning strategies used by female EFL undergraduate students, as well as to explore the relationship of language learning strategies with the two variables: major field of study and performance level in the English language. It also aimed at specifying the English language learning strategies that were associated with the four language skills. The survey method was used on a sample of 264 female EFL undergraduate students who were enrolled in the first and second year of their undergraduate degree programme. Their majors were …


An Investigation Into Hotel Employees' Perception Of Green Practices, Sun-Hwa Kim Jan 2009

An Investigation Into Hotel Employees' Perception Of Green Practices, Sun-Hwa Kim

Electronic Theses and Dissertations

This study examined how employees of the hotel industry perceived green practices. Data was collected from 220 employees working in eight green certified hotels in Orlando. Research results revealed that performance levels of green practices implemented by hotels were lower than the importance levels of those same green practices as perceived by hotel employees. The results of the study illustrated that (1) the employees' perception regarding green practices was not different than one of hoteliers in terms of importance and performance, and (2) employees weighted the green practices that were beneficial to them as more important than green practices that …


Delayed Rejection Of Mhc Class Ii-Disparate Skin Allografts In Mice Treated With Farnesyltransferase Inhibitors, Ken Field Jan 2009

Delayed Rejection Of Mhc Class Ii-Disparate Skin Allografts In Mice Treated With Farnesyltransferase Inhibitors, Ken Field

Faculty Journal Articles

Farnesyltransferase inhibitors (FTIs), developed as anti-cancer drugs, have the potential to modulate immune responses without causing nonspecific immune suppression. We have investigated the possibility that FTIs, by affecting T cell cytokine secretion, can attenuate alloreactive immune responses. The effects of FTIs on murine alloreactive T cells were determined both in vitro, by measuring cytokine secretion or cell proliferation in mixed lymphocyte cultures, and in vivo, by performing skin allografts from H-2bm12mice to MHC class II-disparate B6 mice. We found that two different FTIs, ABT-100 and L-744,832, blocked secretion of IFN-γ, IL-2, IL-4, and TNF-α from naïve …


Roses Are Red, Violets Are Bluehow Poetry In Science Can Help Students Learn Something New, Kimberly Casselman Jan 2009

Roses Are Red, Violets Are Bluehow Poetry In Science Can Help Students Learn Something New, Kimberly Casselman

Electronic Theses and Dissertations

This study was an attempt to examine how poetry integrated with science could assist eighth graders in the memorization of key science vocabulary words. Furthermore, it would investigate if student attitude, interest, and motivation would improve with the use of the poetry. Instruction was adjusted to implement poetry into astronomy lessons. Memorization activities such as poems, chanting, and repetition were used to help students remember the vocabulary and the definitions. Pre/post tests were used to interpret if the poetry did assist in the memorization of the astronomy vocabulary. Science interest surveys and science attitude surveys were used to interpret if …


Changes In Longitudinally Assessed Biomechanical Parameters Related To Increased Risk Of Anterior Cruciate Ligament (Acl) Injuries In Adolescent Female And Male Athletes, Kevin Ray Ford Jan 2009

Changes In Longitudinally Assessed Biomechanical Parameters Related To Increased Risk Of Anterior Cruciate Ligament (Acl) Injuries In Adolescent Female And Male Athletes, Kevin Ray Ford

University of Kentucky Doctoral Dissertations

Females suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate compared to male athletes participating in similar sports. Altered movement patterns and inadequate knee stiffness are two interrelated factors that may increase ACL injury risk. Onset of these neuromuscular risk factors may coincide with the rapid adolescent growth that results in the divergence of a multitude of neuromuscular parameters between sexes. The overall purpose of this dissertation was to determine if neuromuscular ACL injury risk factors in female athletes increase following rapid growth and development compared to males. Male and female athletes were tested with three-dimensional …


Regulation Of Low Density Lipoprotein Receptor Splicing Efficiency, I-Fang Ling Jan 2009

Regulation Of Low Density Lipoprotein Receptor Splicing Efficiency, I-Fang Ling

University of Kentucky Doctoral Dissertations

Low density lipoprotein receptor (LDLR) is an apolipoprotein E (apoE) receptor and may play a role in Alzheimer’s disease (AD) development. A single nucleotide polymorphism (SNP), rs688, that has been identified to modulate the splicing efficiency of LDLR exon 12 and is associated with higher cholesterol and AD in some case-control populations. The exon 12 deleted mRNA is predicted to produce a soluble form of LDLR that fails to mediate apoE uptake. To gain additional insights, in this study, I seek to understand the regulation of LDLR splicing efficiency. To identify functional cis-elements within LDLR exon 12, I mutated several …


Direct Products And The Intersection Map Of Certain Classes Of Finite Groups, Julia Chifman Jan 2009

Direct Products And The Intersection Map Of Certain Classes Of Finite Groups, Julia Chifman

University of Kentucky Doctoral Dissertations

The main goal of this work is to examine classes of finite groups in which normality, permutability and Sylow-permutability are transitive relations. These classes of groups are called T , PT and PST , respectively. The main focus is on direct products of T , PT and PST groups and the behavior of a collection of cyclic normal, permutable and Sylow-permutable subgroups under the intersection map. In general, a direct product of finitely many groups from one of these classes does not belong to the same class, unless the orders of the direct factors are relatively prime. Examples suggest that …


Age May Be Hazardous To Outcome Following Traumatic Brain Injury: The Mitochondrial Connection, Lesley Knight Gilmer Jan 2009

Age May Be Hazardous To Outcome Following Traumatic Brain Injury: The Mitochondrial Connection, Lesley Knight Gilmer

University of Kentucky Doctoral Dissertations

Older individuals sustaining traumatic brain injury (TBI) experience a much higher incidence of morbidity and mortality. This age-related exacerbated response to neurological insult has been demonstrated experimentally in aged animals, which can serve as a model to combat this devastating clinical problem. The reasons for this worse initial response are unknown but may be related to age-related changes in mitochondrial respiration.

Evidence is shown that mitochondrial dysfunction occurs early following traumatic brain injury (TBI), persists long after the initial insult, and is severitydependent. Synaptic and extrasynaptic mitochondrial fractions display distinct respiration capacities, stressing the importance to analyze these fractions separately. …


Droplet Flows In Microchannels Using Lattice Boltzmann Method, Amit Gupta Jan 2009

Droplet Flows In Microchannels Using Lattice Boltzmann Method, Amit Gupta

Electronic Theses and Dissertations

Microelectromechanical systems (MEMS) have widespread applications in medical, electronical and mechanical devices. These devices are characterized by the smallest dimension which is at least one micrometer and utmost one millimeter. Rapid progress in the manufacture and utilization of these microdevices has been achieved in the last decade. Current manufacturing techniques of such devices and channels include surface silicon micromachining; bulk silicon micromachining; lithography; electrodeposition and plastic molding; and electrodischarge machining (EDM). In recent years, electrostatic, magnetic, electromagnetic and thermal actuators, valves, gears and diaphragms of dimensions of hundred microns or less have been fabricated successfully. Sensors have been manufactured that …