Digital Commons Network^™

Substrate Induced Structural And Dynamics Changes In Human Phosphomevalonate Iinase And Implications For Mechanism, Andrew Lawrence Olson, Huili Yao, Timothy J. Herdendorf, Henry M. Miziorko, Supa Hannongbua, Patchareenat Saparpakom, Sheng Cai, Daniel S. Sem

Chemistry Faculty Research and Publications

Phosphomevalonate kinase (PMK) catalyzes an essential step in the mevalonate pathway, which is the only pathway for synthesis of isoprenoids and steroids in humans. PMK catalyzes transfer of the γ-phosphate of ATP to mevalonate 5-phosphate (M5P) to form mevalonate 5-diphosphate. Bringing these phosphate groups in proximity to react is especially challenging, given the high negative charge density on the four phosphate groups in the active site. As such, conformational and dynamics changes needed to form the Michaelis complex are of mechanistic interest. Herein, we report the characterization of substrate induced changes (Mg-ADP, M5P, and the ternary complex) in PMK using …

Children's Production Of Verbal -S By Dialect Type And Clinical Status, Lesli H. Cleveland

LSU Doctoral Dissertations

The study examined children’s use of verbal –s marking (e.g., he walks) in two nonmainstream dialects of English, African American English (AAE), and Southern White English (SWE). Verbal –s marking was of interest because there are gaps in the literature about the nature of this structure within and across typically developing children who speak AAE and SWE and about the nature of this structure in AAE- and SWE-speaking children with specific language impairment (SLI). To address these gaps, children’s verbal –s marking was examined as a function of their dialect and clinical status and as a function of a number …

Extracting Takagi-Sugeno Fuzzy Rules With Interpretable Submodels Via Regularization Of Linguistic Modifiers, Shang-Ming Zhou, John Q. Gan

School of Nursing and Midwifery

No abstract provided.

Faculty Should Consider Peer Review As A Means Of Improving Students' Scientific Reasoning Skills, Briana Timmerman, Denise Strickland

Journal of the South Carolina Academy of Science

No abstract provided.

The Integrated Biomedical Science Graduate Program At The University Of South Carolina, Richard Hunt

Journal of the South Carolina Academy of Science

No abstract provided.

Temperature Changes Resulting From A Gaalas Laser In The Decontamination Of A Failing Dental Implant, Adam B. Oppenheimer

Journal of the South Carolina Academy of Science

No abstract provided.

Reforming The Law Of Crossborder Litigation: Judicial Jurisdiction, Janet Walker

All Papers

This consultation paper prepared for the Law Commission of Ontario, in association with a Working Group of private international law specialists, considers the current state of the common law in Ontario and the options for codification.

Planting The Promised Landscape: Zionism, Nature, And Resistance In Israel/Palestine, Irus Braverman

Journal Articles

This article reveals the complex historical and cultural processes that have led to the symbiotic identification between pine trees and Jewish people in Israel/Palestine. It introduces three tree donation techniques used by Israel, then proceeds to discuss the meaning of nature in Israel, as well as the meaning of planting and rooting in the context of the Zionist project. The article concludes by reflecting on the ways that pine trees absent Palestinian presence and memory from the landscape, and explains how Palestinian acts of aggression toward these pine landscapes relate to the Israel/Palestine relationship.

African Wetlands Of International Importance: Assessment Of Benefits Associated With Designations Under The Ramsar Convention, Royal C. Gardner, Kim Diana Connolly, Abou Bamba

Journal Articles

A party to the Ramsar Convention on Wetlands must designate at least one site within its territory as a Wetland of International Importance. To assess the benefits associated with these international designations, the authors conducted a survey of 26 Ramsar sites in 18 countries in Africa. After a brief introduction to the Ramsar Convention, the article describes the sites that were surveyed, focusing on the ecosystem services they provide and the challenges they face. The article then examines how the sites are identified with the Ramsar Convention and found that designation provided benefits such as: increased support for protection and …

The Sony Legacy: Secondary Liability Perspectives, Robert I. Reis

Journal Articles

No abstract provided.

Private Norms And Public Spaces, Nicole Stelle Garnett

Journal Articles

This Essay explores the role of private norms in the allocation of urban public spaces as well as local governments' efforts to enforce these norms. The Essay was prepared for the 2008 Brigham-Kanner Property Rights Conference, William and Mary School of Law, as a tribute to Robert Ellickson. community policing, informal norms

Trademark Use And The Problem Of Source, Mark P. Mckenna

Journal Articles

This Article mediates a scholarly debate regarding the existence and desirability of a "trademark use" doctrine. It argues that trademark use is a predicate of liability under the Lanham Act, but those who advocate treating trademark use as a threshold question put much more weight on that concept than it can bear. Courts cannot consistently apply trademark use as a distinct element of the plaintiff's prima facie case because trademark use can be determined only from the perspective of consumers. Specifically, courts can determine whether a defendant has made trademark use of a plaintiff's mark only by asking whether consumers …

Standing, Spending, And Separation: How The No-Establishment Rule Does (And Does Not) Protect Conscience, Richard W. Garnett

Journal Articles

The First Amendment’s “Establishment Clause” is widely thought to protect “conscience.” Does it? If so, how? It is proposed in this paper that the no-establishment rule does indeed promote and protect religious liberty, and does safeguard conscience, but not (or, at least, not only) in the way most people think it does, namely, by sparing those who object from the asserted injury to their conscience caused by public funding of religious activity.

The Supreme Court’s decision in Hein v. Freedom from Religion Foundation - a case in which the Justices limited taxpayer standing to bring Establishment Clause claims - reminds …

Does "Proceeds" Really Mean "Net Profits"? The Supreme Court's Efforts To Diminish The Utility Of The Federal Money Laundering Statute, Jimmy Gurulé

Journal Articles

The Supreme Court’s decision in United States v. Santos is severely hampers the fight against drug traffickers, terrorists, mobsters and white collar criminals. It restricts the scope of the money laundering statute, defining the term “proceeds” in it as net profits, not gross receipts from unlawful activity. This imposes an unreasonable and unwarranted burden on prosecutors to prove net criminal profits, money acquired beyond the defendant’s overhead expenses from unlawful activities. The court’s holding also restricts other provisions of the money laundering statute, such as the concealment theory of money laundering, and it creates confusion over whether the Court’s restrictive …

The Federal Common Law Of Nations, Anthony J. Bellia Jr., Bradford R. Clark

Journal Articles

Courts and scholars have vigorously debated the proper role of customary international law in American courts: To what extent should it be considered federal common law, state law, or general law? The debate has reached something of an impasse, in part because various positions rely on, but also are in tension with, historical practice and constitutional structure. This Article describes the role that the law of nations actually has played throughout American history. In keeping with the original constitutional design, federal courts for much of that history enforced certain rules respecting other nations' perfect rights (or close analogues) under the …

Religious Freedom, Church Autonomy, And Constitutionalism, Richard W. Garnett

Journal Articles

Our topic at this symposium is "religion, the state, and constitutionalism"-not "the Constitution," or "the First Amendment," but "constitutionalism." Countless conferences, cases, books, and articles have wrestled with one version or another of the question, "how does our Constitution, with its First Amendment and its religion clauses, promote, protect, or perhaps restrain religion?" We are considering, it seems to me, a question that is different, and that is different in interesting and important ways: What are connections between religion and religious freedom, on the one hand, and constitutionalism, on the other?

Introduction: Unsettling Questions, Disquieting Stories, Mae Kuykendall, David A. Westbrook

Journal Articles

The Business Law and Narrative Symposium, held at Michigan State University on September 10-11, 2009, brought together nationally known legal scholars, and scholars from other disciplines, to discuss whether and how the institution of the corporation was embedded in social narratives, public stories. This introductory essay reviews the responses of these scholars to the thesis of Kuykendall's article, No Imagination: The Marginal Role of Narrative in Corporate Law. The authors conclude with a hope that corporate law might offer a more literary sensibility by which to make our lives in global capitalism more comprehensible.

For Peter, With Love, John Henry Schlegel

Journal Articles

No abstract provided.

The Freedom Ring: Making Grutter Matter In School Desegregation Cases, Rachel F. Moran

University of Miami Law Review

No abstract provided.

Memory Lost: Brown V. Board And The Constitutional Economy Of Liberty And Race, Kenneth M. Casebeer

University of Miami Law Review

No abstract provided.

John Roberts's Formalist Nightmare, Steven L. Winter

University of Miami Law Review

No abstract provided.

Sleight Of Hand Or The Old Bait & Switch?: Article Iii And The Politics Of Self-Policing By The Court In Parents Involved, Zanita E. Fenton

University of Miami Law Review

No abstract provided.

Parents Involved In Community Schools V.Seattle School District No. 1: A Return To A Separate And Unequal Society, Kimberly J. Freedman

University of Miami Law Review

No abstract provided.

The Spirit Of Brown In Parents Involved And Beyond, Shron L. Browne, Elizabeth A. Yi

University of Miami Law Review

No abstract provided.

Cultural Vulnerability And Resilience In The Arctic: Preliminary Report On Archeological Fieldwork At Cape Krusenstern, Northwest Alaska, Shelby L. Anderson, Adam Freeburg, Ben Fitzhugh

Anthropology Faculty Publications and Presentations

While natural scientists track environmental change in response to global warming, less attention has been directed towards human interface with long term Arctic environmental dynamics. Current research at Cape Krusenstern, Alaska, seeks to address this deficit through investigation of human-environmental interactions recorded in archeological and paleoenvironmental data spanning the last 4,000-5,000 years at the Cape, building on the pioneering work conducted at Krusenstern by J. Louis Giddings and Douglas D. Anderson. Systematic survey and use of new mapping technology to record cultural and natural features are methods central to addressing these research questions. Discovery of new archeological features indicates occupation …

Copyright, Trademark And Secondary Liability After Grokster, Mark Bartholomew

Journal Articles

Even though secondary infringement doctrine in both copyright and trademark stems from the same common law starting points, the doctrines have moved in very different directions, particularly in the last decade. As copyright litigants expanded their litigation strategy to include online intermediaries, secondary copyright liability was stretched to encompass a wider array of defendants with increasingly tangential relationships to the direct infringer. Meanwhile, even though similar online threats jeopardized the ability of trademark holders to safeguard their brands' goodwill, courts refused to implement a similar expansion for secondary trademark liability. Although courts are aware of this doctrinal double standard, they …

Contributory Infringers And Good Samaritans, Mark Bartholomew

Journal Articles

The introduction of online technologies has put increased pressure on the doctrine of contributory infringement as intellectual property rights holders switch their attention from direct infringers to Internet intermediaries. The Supreme Court has instructed lower courts to evaluate contributory infringement in light of traditional tort law. The common law of aiding and abetting, however, is so inconsistent as to offer no real guidance. A better approach lies in a separate but related area of tort doctrine. In a limited number of circumstances, tort law recognizes a duty to protect third parties from the actions of others. Like aiding and abetting, …

Cops, Robbers, And Search Engines: The Questionable Role Of Criminal Law In Contributory Infringement Doctrine, Mark Bartholomew

Journal Articles

Online technologies have created a new litigation locus for intellectual property rights holders, one that targets intermediaries, not direct infringers. This unprecedented litigation strategy has put sudden pressure on the courts to evaluate the liability of indirect infringers. Without a developed body of precedent at their disposal, judges have resorted to analogies from the criminal law of accomplice liability to set the boundaries of contributory infringement. Does it make sense for intellectual property regulation to depend on the same principles that animate criminal law? This Article maintains that it would be a mistake to remake contributory infringement law in criminal …

Changing, Not Balancing, The Market: Economic Politics And "Social" Programs, Martha T. Mccluskey

Contributions to Books

Published in Progressive Lawyering, Globalization, and Markets: Rethinking Ideology and Strategy, Claire Dalton, ed.

Private Import Safety Regulation And Transnational New Governance, Errol E. Meidinger

Contributions to Books

Published as Chapter 12 in Import Safety: Regulatory Governance in the Global Economy, Cary Coglianese, Adam M. Finkel & David Zaring, eds.

This paper examines the role of ‘private’ (non-governmental) regulatory programs in assuring the safety of imported products. Focusing particularly on food safety it argues that private regulatory institutions have great capacity to control safety hazards and to implement dynamic systems for detecting and correcting nascent risks. However, to establish the accountability and legitimacy relationships necessary for long-term effectiveness, private safety regulatory programs must devise new ways of incorporating and responding to the interests of developing country producers, laborers, …