Digital Commons Network^™

Deconstructing Wyeth V. Levine: The New Limits On Implied Conflict Preemption, David C. Vladeck

Case Western Reserve Law Review

No abstract provided.

Methicillin-Resistant Staphylococcus Aureus: Pharmacoepidemiologic Assessment Of Common Medications, Aisling R. Caffrey

Open Access Dissertations

Background. Methicillin-resistant Staphylococcus aureus (MRSA) is a prevalent organism, causing serious infections which are difficult and expensive to treat. Despite the implementation of evidence-based infection control practices and development of newer efficacious antibiotics, MRSA infection and colonization rates continue to increase. Treatments for MRSA have received considerable research attention over the past 10 years, yet several gaps in knowledge remain. In particular, controversy regarding the effectiveness of linezolid as compared to vancomycin in treating MRSA infections persists, and few risk factors associated with mupirocin resistance have been identified. Methods. In the first manuscript of this dissertation, we sought to estimate …

Profits Above The Law: China’S Melamine Tainted Milk Incident, Chenglin Liu

Faculty Articles

There are fundamental flaws within China’s food safety regulatory regime that permeate both its supervision system and governing laws. This is especially prevalent within the market structure in the dairy industry. The government continues to fail in regulating the chaotic market forcing competitors to internalize costs, which has resulted in melamine tainted milk.

This tainted milk scandal has resulted in the death of thousands of infants in a number of Asian countries. The scandal was concealed by the Sanlu Group and local government for fear of bad publicity and loss of profits.

The Chinese government should search for a new …

The Effects Of Coaching Strategies For Primary Prevention Of Coronary Heart Disease Involving Asymptomatic Hospital Employees, Gabriel Mario Moreno

Browse all Theses and Dissertations

Introduction: An effective coronary heart disease (CHD) prevention program is needed. Currently, prevention of CHD is being sought through pre-CHD risk stratification of patients using office-based screening tools such as the Framingham risk model (Greenland, Smith, and Grundy, 2001). However, patients who are given recommendations for lifestyle behavior modification find difficulty employing and sustaining the changes. The recent popularity of coaching for health behavior change has prompted the question of whether coaching is an effective method to produce a higher success rate for lowering cardiovascular disease following risk stratification.

The main purpose of this study was to investigate the effectiveness …

Ischemic Stroke In Type Ii Diabetic Mice: Deregulation Of Sdf-1a/Cxcr4 Axis, Avik Das

Browse all Theses and Dissertations

Type 2 diabetes mellitus is a major risk factor for ischemic stroke. Also diabetes is associated with poor outcome after stroke. Underlying mechanisms are however not fully understood. Alteration in the expression of the SDF-1a/CXCR4 axis, which is important for ischemic tissue repair, can be a probable cause. In this study, we have determined the expression of SDF-1a/CXCR4 in the brains of type II diabetic mice at basal and in response to ischemic stroke and have investigated a method for overexpression of SDF-1a in the brains of the diabetic mice. Adult male C57BLKS/J mice (db/db) of age 8 weeks were …

Ion Transport Mechanisms During Hyposmotic Regulatory And Isosmotic Apoptotic Volume Decreases In A Human Lens Epithelial Cells Line, Ameet Ajit Chimote

Browse all Theses and Dissertations

Living cells maintain constant volume in response to physiological stresses by altering trans-membrane ion, solute and water flow. In the present study, early and late membrane transport changes in human lens epithelial (HLE-B3) cells under hyposmotic and apoptotic stress were compared. Cell potassium (Ki), rubidium (Rbi)-uptake and water content were measured by atomic absorption spectrophotometry and gravimetry, respectively. Intracellular chloride concentration [Cl]i was determined with the fluorescence dye N- (ethoxycarbonylmethyl)-6-methoxyquinolinium bromide (MQAE), during regulatory volume decrease (RVD) after hyposmotic stress and apoptotic volume decrease (AVD) induced by staurosporine (STP), a protein-kinase inhibitor. Cell water increased in hyposmotic balanced salt solution …

Finding The Trophic Trickle: Using Herbaceous Indicator Species To Investigate Plant Recovery From Intense Browsing By White-Tailed Deer (Odocoileus Virginianus) After The Re-Colonization Of A Top Predator (Canis Lupus), Krystle A. Bouchard

Browse all Theses and Dissertations

High densities of white-tailed deer (Odocoileus virginianus) have been implicated in changing forest community structure and composition. Top predators, including gray wolf (Canis lupus), were extirpated from much of their range by the mid 1900s, but have since returned to Northern Wisconsin. To determine whether the re-colonization of wolves could initiate a trophic cascade resulting in the recovery of understory plants from deer browsing, I surveyed four herbaceous species in areas without wolves and areas with 4-6 year old wolf packs and 12-13 year old wolf packs. Plant size and reproduction were greater in areas where wolves had been for …

Hif-1 Alpha: A Master Regulator Of Trophoblast Differentiation And Placental Development, Kashmira Kulkarni

Browse all Theses and Dissertations

Early embryonic development occurs under low oxygen levels. The placenta is an organ transiently formed during pregnancy and plays a crucial role during development of the embryo. Alterations in the placental structure or function have been associated with the pathologies such as preeclampsia in humans. In mammals, the hypoxia inducible factor (HIF) transcription factors have been identified as the major regulators of cellular responses in low oxygen. In the current study, we investigated the effects of low oxygen on the differentiation of trophoblast stem cells, lineage committed trophoblast giant cells and labyrinthine lineage-committed cells. We examined the effects of an …

The Pleading Problem, Adam N. Steinman

Articles

Federal pleading standards are in crisis The Supreme Courts recent decisions in Bell Atlantic Corp v Twombly and Ashcroft v Iqbal have the potential to upend civil litigation as we know it What is urgently needed is a theory of pleading that can bring Twombly and Iqbal into alignment with the text of the Federal Rules of Civil Procedure and a halfcentury worth of Supreme Court precedent while providing a coherent methodology that preserves access to the courts and allows pleadings to continue to play their appropriate role in the adjudicative process This Article provides that theory It develops a …

The Influence Of Temperature On Population Growth And Allergen Production In Cultured House Dust Mites - Dermatophagoides Pteronyssinus And Dermatophagoides Farinae, Lakshmi Yella

Browse all Theses and Dissertations

Dermatophagoides pteronyssinus and Dermatophagoides farinae are commercially cultured to produce materials to make extracts for diagnostic tests and immunotherapy. There is some speculation as to how the culture conditions such as time of culture, temperature, relative humidity and food might influence the mite populations and subsequent production of allergens. The purpose of our investigation was to see how temperature influenced the population growth and allergen production of cultured house dust mites. D. pteronyssinus and D. farinae were cultured at 20°C and 25°C. Samples were collected at two week intervals for live mite count, life stage composition and to determine Group …

Promoting Mental Health Occupational Therapy In Higher Education: Lifestyle Redesign® For The College Student, Karen Mccarthy

Collected Faculty Scholarship

No abstract available

Eatin' Good? Not In This Neighborhood: A Legal Analysis Of Disparities In Food Availability And Quality At Chain Supermarkets In Poverty-Stricken Areas, Nareissa Smith

Michigan Journal of Race and Law

Many Americans-especially the poor-face severe hurdles in their attempts to secure the most basic of human needs-food. One reason for this struggle is the tendency of chain supermarkets to provide a limited selection of goods and a lower quality of goods to patrons in less affluent neighborhoods. Healthier items such as soy milks, fresh fish, and lean meats are not present in these stores, and the produce that is present is typically well past the peak of freshness. Yet, if the same patron were to go to another supermarket owned by the same chain--but located in a wealthier neighborhood-she would …

Generating Sustainable Weight Loss: Investigating The Efficacy Of A Behavioral Based Weight Loss Intervention, Michael James Bordieri

Theses

Two thirds of Americans are overweight or obese. Traditional obesity interventions (e.g. drug therapy, diets, behavior therapy) generate moderate short-term weight loss but have little evidence of long-term weight maintenance. The cultural phenomenon of "yo-yo dieting" mirrors empirical findings which suggest that weight loss, albeit demanding, is a far easier process to target than weight maintenance. The present study sought to evaluate the efficacy of an acceptance based behavioral intervention designed to generate improvements in psychological health and quality of life in obese and overweight adults as well as encourage gradual and sustainable weight loss. The therapy package combined the …

Understanding The Link Between Ethanol Production And Food Prices, Nathalia Ferreira Monteiro

Theses

Food prices have increased rapidly in recent years, and so has ethanol consumption. Some studies have claimed that there is a connection between those two. Net exporters of food tend to benefit from higher prices, while regions that are net importers of food, tend to be adversely affected. The large amount of poor countries in the second group justifies an investigation of the causes of increasing food prices. This thesis aims to contribute to the discussion, analyzing, theoretically and empirically, the impact that the diversion of feedstock from food to ethanol production has on food prices. The interaction between food …

Government Auditing Standards And Circular A-133 Developments - 2009; Audit Risk Alerts, American Institute Of Certified Public Accountants

Industry Guides (AAGs), Risk Alerts, and Checklists

No abstract provided.

Concentration Of Metabolites And Behavior Of Live Weight In Llamas (Lama Glama) Fed With Natural Grass And Barley During Gestation, Postpartum, And New Born Phases In Turco, Department Of Oruro, Eduardo Ticona Benique

Theses and Dissertations

The llama, a potential socioeconomic resource in the Bolivian highlands, faces serious nutritional deficiencies during the gestational and postpartum stages that negatively affect production. This study was conducted at the Tika Huta Experimental Center in the Llachu community of the Oruro prefecture. Our objectives were to determine metabolite concentration in blood plasma as well as live weight performance of pregnant and postpartum female llamas. Adult and juvenile llamas were fed diets of either plain natural grass or natural grass combined with 0.4 kg of barley hay. In addition, we determined metabolite concentrations in blood plasma and live weight performance of …

Trials And Tribulations: What Happens When Historians Enter The Courtroom, David Rosner

Law and Contemporary Problems

In recent years, historians have been brought into legal cases in unprecedented numbers. As the courts have tried to adjudicate responsibility for environmental and occupational diseases, history has played an increasingly central role in decisions that affect the cases themselves and in social policy regarding risk. In suits over tobacco-related diseases, asbestosis, radiation, and other toxic substances, more historians of technology and science, social history, and public health are being sought to provide testimony aimed at assessing responsibility for damages that have arisen years--sometimes decades--after exposure. Here, Rosner traces the use of historians as experts in litigation.

Dog Neglect, Christopher Garcia

Digressions: Literary & Art Journal

No abstract provided.

A Longitudinal Examination Of The Contribution Of Perceived Motor Competence And Actual Motor Competence To Physical Activity In 6 To 9 Year Old Children, Fleur Mcintyre

Theses

This study examined the relationship between perceived motor competence, actual motor competence and physical activity. In particular, it aimed to identify the impact of perceived motor competence (PMC), actual motor competence (AMC), and age and gender on the physical activity levels of young children. A number of factors have been identified as key contributors to children’s physical activity levels. However, there had been little investigation into their developing impact and subsequent relationship with emergent physical activity levels, particularly in the younger primary age groups.

Physical activity, AMC and PMC measures were collected from 6-, 7-, 8-, and 9-year-old boys and …

Advertising Obesity: Can The U.S. Follow The Lead Of The Uk In Limiting Television Marketing Of Unhealthy Foods To Children?, David Darwin

Vanderbilt Journal of Transnational Law

Childhood obesity has tripled in the U.S. since the 1970s, and television advertisement of unhealthy foods has been linked to the unhealthy eating habits of children. The United Kingdom, facing a similar problem, promulgated regulations in 2007 banning the advertisement of foods high in fat, sodium, and sugar during programming directed at children below age 16.

In the U.S., industry representatives, public policy advocates, and government officials are debating whether to rely on self-regulation efforts or to implement government-established guidelines. Industry representatives argue that government guidelines would do little to solve the childhood obesity problem and that the UK regulations …

The Emperor Is Still Naked: Why The Protocol On The Rights Of Women In Africa Leaves Women Exposed To More Discrimination, Kristin Davis

Vanderbilt Journal of Transnational Law

The Protocol to the African Charter on Human and Peoples' Rights on the Rights of Women in Africa entered into force in 2005. Met with much celebration for the protection it would provide African women, the Protocol was heralded as one of the most forward-looking human rights instruments. Now, fifteen years after it was conceived, the Protocol deserves a full assessment of the issues that it has faced in accession and will face in implementation. This Note analyzes the way in which the Protocol was developed and the effect the Protocol's language will have on its ability to achieve its …

Strafford County 2008 Annual Report Of The Commissioners, Treasurer, Other County Officers And The Strafford County Delegation Strafford County, New Hampshire For The Year Ending December 31, 2008., Stafford County Representatives

Strafford County, NH Annual Reports

This is an annual report containing vital statistics for a county in the state of New Hampshire.

Response To Nicholas Boyle, O. Carter Snead

Journal Articles

Response to Nicholas Boyle’s talk “God, Sex, and America: From Decline of the Common Morality to the Emergence of a Global Ethical Life” at The Catholic University of America Center for Law, Philosophy and Culture’s Symposium “A Common Morality for the Global Age: In Gratitude for What We Are Given.”

International Trade And World Health Policy: Helping People Reach Their Full Potential, Phillip Countryman

Pace International Law Review

No abstract provided.

Video-Tracking And On-Plant Tests Show Cry1ab Resistance Influences Behavior And Survival Of Neonate Ostrinia Nubilalis Following Exposure To Bt Maize, Jarrad R. Prasifka, Richard L. Hellmich, Andre L. B. Crespo, Blair Siegfried, David W. Onstad

Department of Entomology: Faculty Publications

To examine how resistance to Bacillus thuringiensis (Bt) toxins influences movement and survival of European corn borer (Ostrinia nubilalis [Hübner]) neonates, the responses of Cry1Ab-resistant , -susceptible, and hybrid (F1) larvae were examined using two different techniques. First, using an automated videotracking system, aspects of O. nubilalis movement were quantified in the presence of artificial diet incorporating 50% non-Bt or insect-resistant Cry1Ab maize tissue. Second, O. nubilalis dispersal and survival were measured 48–72 h after hatching on a Cry1Ab maize plant surrounded by two non-Bt maize plants. Video tracking indicated the presence of Cry1Ab tissue increased the total distance …

Gene Expression Profiling Of Tolerant Barley In Response To Diuraphis Noxia (Hemiptera: Aphididae) Feeding, A. Gutsche, Tiffany Heng-Moss, Gautam Sarath, P. Twigg, Yuannan Xia, G. Lu, D. Mornhinweg

Department of Entomology: Faculty Publications

Aphids are, arguably, the single most damaging group of agricultural insect pests throughout the world. Plant tolerance, which is a plant response to an insect pest, is viewed as an excellent management strategy. Developing testable hypotheses based on genome-wide and more focused methods will help in understanding the molecular underpinnings of plant tolerance to aphid herbivory. As a first step in this process, we undertook transcript profiling with Affymetrix GeneChip Barley Genome arrays using RNA extracted from tissues of tolerant and susceptible genotypes collected at three hours, three days and six days after Diuraphis noxia introduction. Acquired data were compared …

Using The World Wide Web To Educate And Inform The Public About Risk And Agricultural Biotechnology, Douglas A. Golick, Robert D. Peterson, Leon G. Higley

Department of Entomology: Faculty Publications

The University of Nebraska and AgBios, Inc. launched the AgBiosafety website (http://agbiosaftzy.unl.edu) with the purpose of educating the public about agricultural biotechnology risk and safezy issues through science-based content. This article discusses the creation ofthe website, its components, and data gathered from usage statistics and a web-delivered survey. Also included is a discussion of the results ofdata gathered and recommendations for future web-based educational efforts in biotechnology safety and risk assessment.

Genes Differentially Expressed By Cumulus Cells And Assays Using Same To Identify Pregnancy Competent Oocytes, Jose B. Cibelli, Amy E. Iager, Hasan H. Otu

Department of Electrical and Computer Engineering: Faculty Publications

A genetic means of identifying "pregnancy competent" oocytes is provided. The means comprises detecting the level of expression of one or more genes that are expressed at characteristic levels (upregulated or downregulated) in cumulus cells derived from pregnancy competent oocytes. This characteristic gene expression level, or pattern referred to herein as the "pregnancy signature", also can be used to identify subjects with underlying conditions that impair or prevent the development of a viable pregnancy, e.g., pre-menopausal condition, other hormonal dysfunction, ovarian dysfunction, ovarian cyst, cancer or other cell proliferation disorder, autoimmune disease and the like. In preferred embodiments the …

Predatory Senescence In Ageing Wolves, Daniel R. Macnulty, Douglas W. Smith, John A. Vucetich, L. David Mech, Craig Packer

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

It is well established that ageing handicaps the ability of prey to escape predators, yet surprisingly little is known about how ageing affects the ability of predators to catch prey. Research into long-lived predators has assumed that adults have uniform impacts on prey regardless of age. Here we use longitudinal data from repeated observations of individually-known wolves (Canis lupus) hunting elk (Cervus elaphus) in Yellowstone National Park to demonstrate that adult predatory performance declines with age and that an increasing ratio of senescent individuals in the wolf population depresses the rate of prey offtake. Because this ratio fluctuates independently of …

Problems With The Claim Of Ecotype And Taxon Status Of The Wolf In The Great Lakes Region, Matthew A. Cronin, L. David Mech

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Koblmuller et al. (2009) analyzed molecular genetic data of the wolf in the Great Lakes (GL) region of the USA and concluded that the animal was a unique ecotype of grey wolf and that genetic data supported the population as a discrete wolf taxon. However, some of the literature that the researchers used to support their position actually did not, and additional confusion arises from indefinite use of terminology. Herein, we discuss the problems with designation of a wolf population as a taxon or ecotype without proper definition and assessment of criteria.

Koblmuller et al. (2009) wrote ‘The GL …