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2009

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The Debate Over Deference In The Erisa Setting - Judicial Review Of Decisions By Conflicted Fiduciaries, Roy F. Harmon Iii Jan 2009

The Debate Over Deference In The Erisa Setting - Judicial Review Of Decisions By Conflicted Fiduciaries, Roy F. Harmon Iii

South Dakota Law Review

No abstract provided.


Degree Of Vocal Handicap In Two Age Groups Of Individuals, Whitney N. Casey-Heatherman Jan 2009

Degree Of Vocal Handicap In Two Age Groups Of Individuals, Whitney N. Casey-Heatherman

Theses, Dissertations and Capstones

A healthy, functional voice is a critical aspect of daily life, allowing the expression of basic needs as well as interaction within an individual’s community. Unfortunately, for many adults the voice declines in later life. The purpose of this study was to investigate how normal vocal aging affects the quality of life of the elderly. Two hundred two adults without voice disorders from two age groups (30-50 and 65-85) completed the Voice Handicap Index. Results indicated that the older group felt a greater degree of vocal handicap than the younger age group [F (1,156) = 4.944, p = 0.028]. Implications …


Children’S Futures: Lessons From A Second-Generation Community Change Initiative, Karen E. Walker, Claire Gibbons, Marco Navarro Jan 2009

Children’S Futures: Lessons From A Second-Generation Community Change Initiative, Karen E. Walker, Claire Gibbons, Marco Navarro

The Foundation Review

· This article describes Children’s Futures, a 10-year initiative in Trenton, N.J., that seeks to improve the health and well-being of children from 0 to 3 years old and ensure that they are ready for school.

· During the first five years, the initiative was successful in implementing a number of evidence-based practices to improve children’s health, such as providing home visits to pregnant women, measuring and improving the quality of day care centers, and improving the use of information systems to track childhood immunizations.

· Efforts to provide services for fathers and improve home-based child care were not successful; …


The Blind Men And The Elephant: Learning A Little At A Time About Civic Engagement, Melanie Moore Kubo, Ashley Mckenna Jan 2009

The Blind Men And The Elephant: Learning A Little At A Time About Civic Engagement, Melanie Moore Kubo, Ashley Mckenna

The Foundation Review

· This article, written from the perspective of the evaluator, describes what happened in one community in which four noncollaborating funders were supporting community development programs.

· The Treeline Collaborative evolved from grassroots origins to become a leading organization in the community, serving as a one-stop shop for many programs and providing a structure for civic engagement of residents.

· A collaborative evaluation would have enabled a deeper understanding of the Treeline Collaborative, the outcomes it attained and missed, and the multiple roles it plays in the community, perhaps leading to more effective program and funding decisions.


A Model For Multilevel Advocacy Evaluation, Tanya Beer, Ehren D. Reed Jan 2009

A Model For Multilevel Advocacy Evaluation, Tanya Beer, Ehren D. Reed

The Foundation Review

· The Colorado Trust provided three years of general operating support to nine advocacy organizations working to increase access to health through policy change work.

· The nine grantees had a variety of goals and strategies and had different levels of organizational capacity, but were evaluated using a uniform evaluation approach.

· The evaluation was designed to build grantees’ own evaluation capacity to incorporate real-time feedback, monitor progress toward goals, and to assess growth in the overall health advocacy community in Colorado.

· Individual grantees identified short- and intermediate- term outcomes related to The Trust’s intermediate outcomes, which were in …


Rarely Tried, And - Rarely Successful: Theoretically Impossible Price Predation Among The Airlines, Chris Sagers Jan 2009

Rarely Tried, And - Rarely Successful: Theoretically Impossible Price Predation Among The Airlines, Chris Sagers

Journal of Air Law and Commerce

No abstract provided.


Method Against Method: Swarm And Interdisciplinary Research Methodology, Dylan E. Wittkower Jan 2009

Method Against Method: Swarm And Interdisciplinary Research Methodology, Dylan E. Wittkower

Philosophy Faculty Publications

Part of a special issue on “swarm methodology,” this paper, written by a swarm participant, reflects upon the purpose and value of this kind of interdisciplinary research methodology. First, by way of a recognition of the interdisciplinary status of this paper itself, the question of what we hope to accomplish when we engage in conversations across disciplinary boundaries is broached. Second, a discussion of the practice of peer-review provides an approximate view of one paradigmatic understanding of how we produce a “conversation” within a given established research methodology. We are then, third, able to consider a number of possible related …


Alterations In Default Network Connectivity In Posttraumatic Stress Disorder Related To Early Life Trauma, Robyn L. Bluhm, Peter C. Williamson, Elizabeth A. Osuch, Paul A. Frewen, Todd K. Stevens, Kristine Boksman, Richard W.J. Neufeld, Jean Théberge, Ruth A. Lanius Jan 2009

Alterations In Default Network Connectivity In Posttraumatic Stress Disorder Related To Early Life Trauma, Robyn L. Bluhm, Peter C. Williamson, Elizabeth A. Osuch, Paul A. Frewen, Todd K. Stevens, Kristine Boksman, Richard W.J. Neufeld, Jean Théberge, Ruth A. Lanius

Philosophy Faculty Publications

Background: The "default network" consists of a number of brain regions that exhibit correlated low-frequency activity at rest and that have been suggested to be involved in the processing of self-relevant stimuli. Activity in many of these areas has also been shown to be altered in individuals with posttraumatic stress disorder (PTSD). We hypothesized that the posterior cingulate cortex (PCC)/precuneus, part of the default network, would exhibit altered connectivity at rest with other areas of the default network and regions associated with PTSD.

Methods: Seventeen medicated and unmedicated female patients with chronic posttraumatic stress disorder (PTSD) related to early-life trauma …


Resting State Default-Mode Network Connectivity In Early Depression Using A Seed Region-Of-Interest Analysis: Decreased Connectivity With Caudate Nucleus, Robyn Bluhm, Peter Williamson, Ruth Lanius, Jean Théberge, Maria Densmore, Robert Bartha, Richard Neufeld, Elizabeth Osuch Jan 2009

Resting State Default-Mode Network Connectivity In Early Depression Using A Seed Region-Of-Interest Analysis: Decreased Connectivity With Caudate Nucleus, Robyn Bluhm, Peter Williamson, Ruth Lanius, Jean Théberge, Maria Densmore, Robert Bartha, Richard Neufeld, Elizabeth Osuch

Philosophy Faculty Publications

Aim: Reports on resting brain activity in healthy controls have described a default-mode network (DMN) and important differences in DMN connectivity have emerged for several psychiatric conditions. No study to date, however, has investigated resting-state DMN in relatively early depression before years of medication treatment. The objective of the present study was, therefore, to investigate the DMN in patients seeking help from specialized mental health services for the first time for symptoms of depression.

Methods: Fourteen depressed subjects and 15 matched controls were scanned using 4-T functional magnetic resonance imaging while resting with eyes closed. All but one subject was …


Home, Jennifer Davis Jan 2009

Home, Jennifer Davis

The Mercury

No abstract provided.


The Future Of Neuroimaged Lie Detection And The Law, Joelle A. Moreno Jan 2009

The Future Of Neuroimaged Lie Detection And The Law, Joelle A. Moreno

Faculty Publications

No abstract provided.


Benthic Algae (Except Bacillariophyta) And Their Seasonal Variations In Karagöl Lake (Borçka, Artvin-Turkey), Saadet Kolayli, Bülent Şahi̇n Jan 2009

Benthic Algae (Except Bacillariophyta) And Their Seasonal Variations In Karagöl Lake (Borçka, Artvin-Turkey), Saadet Kolayli, Bülent Şahi̇n

Turkish Journal of Botany

Seasonal variation in the species composition of the benthic algae of Karagöl Lake was investigated from April to October in 2001 and 2002. The benthic algal flora consisted of 38 taxa belonging to the divisions Chlorophyta, Cyanophyta, Euglenophyta, and Chrysophyta. In general, Chlorophyta were dominant in terms of species number and abundance during the study period. The distribution range of the benthic algae composition and dominant species differed from each other at all stations. Benthic algal growth was mostly influenced by water temperature and light.


Fatty Acid Content And Composition Of Turkish Beef And Lamb At Retail, Leyla Vatansever, Gülcan Demi̇rel Jan 2009

Fatty Acid Content And Composition Of Turkish Beef And Lamb At Retail, Leyla Vatansever, Gülcan Demi̇rel

Turkish Journal of Veterinary & Animal Sciences

The fatty acid content and chemical composition of retail samples of beef and lamb meat were investigated. Fifty beef and lamb chops were purchased from different supermarkets in İstanbul on separate occasions. The average muscle fatty acid content was 2395 and 2257 mg/100 g of muscle for beef and lamb, respectively. Saturated and polyunsaturated fatty acid contents were 1000 and 940 mg/100 g, and 199 and 261 mg/100 g of muscle for beef and lamb, respectively. Overall results indicate that, particularly before the Sacrifice Holiday, concentrate-based feeding of livestock increases and this has an adverse effect on the n-6/n-3 ratio …


Detection Of Bordetella Avium By Polymerase Chain Reaction In The Lungs And Tracheas Of Turkeys With Pneumonia, Süheyla Türkyilmaz, Sevi̇n Kirdar, Fulya Ocak, Şebnur Hazimoğlu Jan 2009

Detection Of Bordetella Avium By Polymerase Chain Reaction In The Lungs And Tracheas Of Turkeys With Pneumonia, Süheyla Türkyilmaz, Sevi̇n Kirdar, Fulya Ocak, Şebnur Hazimoğlu

Turkish Journal of Veterinary & Animal Sciences

Lung, trachea, and serum samples obtained from turkeys showing clinical signs of respiratory disease were examined for the presence of Bordetella avium infection (bordetellosis) using culture, enzyme-linked immunosorbent assay (ELISA), and polymerase chain reaction (PCR). The material of this study consisted of 2 live turkeys at the age of 24 weeks with respiratory distress, nasal discharge, and cough that had been brought to the Microbiology Laboratory of the Faculty of Veterinary Medicine, Adnan Menderes University. The results of the study show that B. avium, the causative agent of bordetellosis, was not isolated from either the lung or trachea, while both …


Pulmonary Aspergillosis And Amyloid Accumulation In An Ostrich (Struthio Camelus), Ahmet Akkoç, Rahşan Yilmaz, İ. Taci̇ Cangül, M. Özgür Özyi̇ği̇t Jan 2009

Pulmonary Aspergillosis And Amyloid Accumulation In An Ostrich (Struthio Camelus), Ahmet Akkoç, Rahşan Yilmaz, İ. Taci̇ Cangül, M. Özgür Özyi̇ği̇t

Turkish Journal of Veterinary & Animal Sciences

Fatal pulmonary aspergillosis and AA type amyloid accumulations in the liver and spleen are described in a female ostrich (Struthio camelus). The animal had had respiratory problems and long-term inappetence over an 8-week period. Necropsy revealed that several soft, grayish to white nodules ranging from 1 to 3 mm in diameter were scattered throughout the lungs and thoracic air sacs. Prominent enlargement of the liver and spleen was observed. No gross lesions were found in the other organs studied. The microscopic examination showed severe, necrotizing, granulomatous pneumonia, and air sacculitis. Aspergillus fumigatus was recovered from the lungs and air sacs …


Thermoregulation Differs In Chinampo (Bos Taurus) And Locally Born Dairy Cattle, Jose L. Espinoza, Jesus Sanchez, Jose A. Gracia, Jesus R. Sanchez, Ricardo Ortega, Alejandro Palacios Jan 2009

Thermoregulation Differs In Chinampo (Bos Taurus) And Locally Born Dairy Cattle, Jose L. Espinoza, Jesus Sanchez, Jose A. Gracia, Jesus R. Sanchez, Ricardo Ortega, Alejandro Palacios

Turkish Journal of Veterinary & Animal Sciences

In order to evaluate heat tolerance, physiological constants of 32 cows were measured (Chinampo: n = 12; Holstein: n = 10; Jersey: n = 10). From June to December 2006, rectal temperature and respiratory rate were recorded every Monday at 0600 and 1700 h. Holstein rectal temperature was affected by heat most, followed by Jersey, and Chinampo (the most heat-resistant). Respiratory rate of the 3 breeds was affected by climatic factors, but the Holstein and Jersey cows registered values higher than those of Chinampo cows. With a temperature-humidity index (THI) above 72 the physiological variables of all 3 breeds increased. …


The Effect Of Acupuncture Therapy On The Repair Of The Calcaneal Tendon (Tendo Calcaneus Communis) In Dogs, Davood Sharifi, Jalal Bakhtiari, Fahang Sasani, Taher Rezaei Jan 2009

The Effect Of Acupuncture Therapy On The Repair Of The Calcaneal Tendon (Tendo Calcaneus Communis) In Dogs, Davood Sharifi, Jalal Bakhtiari, Fahang Sasani, Taher Rezaei

Turkish Journal of Veterinary & Animal Sciences

The effect of acupuncture therapy on the healing process of the calcaneal tendon (tendo calcaneus communis) of the dog was evaluated after tendon splitting in 10 adult mixed breed dogs. Complete, full thickness splitting of the right Achilles tendon, 2 cm in length, was performed using a scalpel blade. The dogs were randomly divided into 2 groups (group 1 and 2) of 5 dogs each. The dogs in group 2 were subjected to acupuncture therapy 10 min/day for 2 weeks, starting on postoperative day 3. The acupuncture points used were GB30, BL40, and ST36. No treatment was given to group …


Use Of Oxalic Acid To Control Varroa Destructor In Honeybee (Apis Mellifera L.) Colonies, Ethem Akyol, Hali̇l Yeni̇nar Jan 2009

Use Of Oxalic Acid To Control Varroa Destructor In Honeybee (Apis Mellifera L.) Colonies, Ethem Akyol, Hali̇l Yeni̇nar

Turkish Journal of Veterinary & Animal Sciences

This study was carried out to determine the effects of oxalic acid (OA) on reducing Varroa mite (Varroa destructor) populations in honeybee (Apis mellifera L.) colonies in the fall. Twenty honeybee colonies, in wooden Langstroth hives, were used in this experiment. Average Varroa infestation levels (%) of the OA and control groups were 25.87% and 24.57% on adult workers before the treatments. The OA treatments were applied twice, on 3 November and 13 November 2006. Average Varroa infestation levels were 5.24% and 31.43% after the first application and 2.87% and 41.74% after the second application in the OA and control …


Description Of Dogs Naturally Infected With Hepatozoon Canis In The Aegean Region Of Turkey, Serdar Paşa, Funda Kiral, Tüli̇n Karagenç, Abi̇di̇n Atasoy, Kami̇l Seyrek Jan 2009

Description Of Dogs Naturally Infected With Hepatozoon Canis In The Aegean Region Of Turkey, Serdar Paşa, Funda Kiral, Tüli̇n Karagenç, Abi̇di̇n Atasoy, Kami̇l Seyrek

Turkish Journal of Veterinary & Animal Sciences

Clinical and laboratory findings recorded in 10 dogs naturally infected with Hepatozoon canis in the Aegean region of Turkey were reported. The diagnosis was made by finding H. canis gamonts within leucocytes in Giemsa-stained blood smears. H. canis parasitaemia level was calculated manually by counting 500 neutrophils in blood smears. Parasitaemia varied from 1% to 23% of the circulating neutrophils. Anorexia, fever, depression, weight loss, and lymphadenopathy are the main clinical signs in infected dogs. All dogs had microcytic normochromic anaemia; however, 7 of the dogs had neutrophilia, 1 had lymphopenia, 2 had monocytosis, 1 had eosinophilia, and 9 had …


Levels Of Tetracycline Residues In Cattle Meat, Liver, And Kidney From A Slaughterhouse In Tabriz, Iran, Mehran Mesgari Abasi, Mohammad Reza Rashidi, Afshin Javadi, Maryam Bannazadeh Amirkhiz, Solmaz Mirmahdavi, Maryam Zabihi Jan 2009

Levels Of Tetracycline Residues In Cattle Meat, Liver, And Kidney From A Slaughterhouse In Tabriz, Iran, Mehran Mesgari Abasi, Mohammad Reza Rashidi, Afshin Javadi, Maryam Bannazadeh Amirkhiz, Solmaz Mirmahdavi, Maryam Zabihi

Turkish Journal of Veterinary & Animal Sciences

Total of 500 samples from triceps, gluteal and diaphragm muscles, kidney, and liver, were obtained randomly from beef carcasses of a slaughterhouse in Tabriz. We measured oxytetracycline, tetracycline, and chlortetracycline (TCs) residues by high performance liquid chromatography (HPLC) method. Seventy four percent of samples (380 samples) had detectable TCs residues. The mean amounts of oxytetracycline, tetracycline, and chlortetracycline residues in all samples were 52.2, 33.8, and 125.2 µg/kg, respectively. The mean amounts of total residues of TCs in all meat samples, triceps, gluteal and diaphragm muscles, kidney, and liver were 131.0, 163.1, 63.4, 166.7, 408.1, and 254.9 µg/kg, respectively. Five …


Comparison Of Trauma Scores For Adults Who Fell From Height As Survival Predictivity, Mehmet Eryilmaz, Murat Durusu, Öner Menteş, Tahi̇r Özer, Seli̇m Kiliç, Gürkan Ersoy, Özcan Altinel, Murat Kalemoğlu, Nurkan Törer Jan 2009

Comparison Of Trauma Scores For Adults Who Fell From Height As Survival Predictivity, Mehmet Eryilmaz, Murat Durusu, Öner Menteş, Tahi̇r Özer, Seli̇m Kiliç, Gürkan Ersoy, Özcan Altinel, Murat Kalemoğlu, Nurkan Törer

Turkish Journal of Medical Sciences

Aim: Falls from a height and their subsequent injuries and traumas can cause morbidity and death. In the present study, ISS, NISS, RTS, and TRISS values were analyzed to assess mortality probabilities of patients who fell from a height. Materials and Methods: Patients' age, gender, height of falls (0-2 m, 3-5 m, and 6 m and above), organ pathologies, and ISS, NISS, RTS, and TRISS scores were evaluated in terms of mortality. Results: Regarding the survival rate, no statistically significant difference was found between age and gender (P > 0.05). We determined that all trauma scores were correlated with mortality, and …


A Simple Surgical Technique For Repair Of Iridodialysis, Şengül Özdek, Mehmet Cüneyt Özmen Jan 2009

A Simple Surgical Technique For Repair Of Iridodialysis, Şengül Özdek, Mehmet Cüneyt Özmen

Turkish Journal of Medical Sciences

A simple surgical technique is described for repair of iridodialysis and a traumatic iridodialysis case is presented. In this technique, a 10-0 polypropylene suture is used for repair. The knot is left in the anterior chamber to avoid suture related complications such as erosion, patient discomfort, and infection. This technique can be a safe and easy way to repair large iridodialysis.


Linear And Whorled Nevoid Hypermelanosis In Trisomy 13, Şengül Yüksel, Serap Savaci, Uğur Biçak, Cengi̇z Yakinci, Bülent Mizrak Jan 2009

Linear And Whorled Nevoid Hypermelanosis In Trisomy 13, Şengül Yüksel, Serap Savaci, Uğur Biçak, Cengi̇z Yakinci, Bülent Mizrak

Turkish Journal of Medical Sciences

Linear and whorled nevoid hypermelanosis (LWNH) is a reticulate pigmentary disorder with a sporadic occurrence, generally representing a genetic mosaicism. In this case, we describe a two-month-old girl with trisomy 13, who presented with various systemic anomalies such as congenital ventricular septal defect, microcephaly, auricular deformities, flatness of nasal root, overlapping fingers, umbilical hernia, and LWNH. G-banding chromosomal analyses were performed on cultured peripheral blood lymphocytes of the patient and the parents. The karyotype of the patient was 47, XX,+13[100], with no mosaicism. The karyotypes of the parents were normal. To our knowledge, we present the first patient with LWNH …


Factors Affecting Quality Of Life In Patients With Coronary Heart Disease, Tahi̇r Durmaz, Özcan Özdemi̇r, Burcu Akyunak Özdemi̇r, Telat Keleş, Ni̇hal Akar Bayram, Engi̇n Bozkurt Jan 2009

Factors Affecting Quality Of Life In Patients With Coronary Heart Disease, Tahi̇r Durmaz, Özcan Özdemi̇r, Burcu Akyunak Özdemi̇r, Telat Keleş, Ni̇hal Akar Bayram, Engi̇n Bozkurt

Turkish Journal of Medical Sciences

Background: Cardiovascular diseases are currently the most common cause of death worldwide and associated with significant impairment of quality of life (QOL). In this study, we aimed to evaluate the QOL patients with coronary heart disease (CHD) in our country and the factors associated with QOL in these patients. Materials and Methods: The study population was composed of 85 patients diagnosed with stable CHD. The data were collected using Ferrans and Powers' Quality of Life Index Cardiac Version- IV and the query designed by the investigators. Results: Eighty-five patients (29 female, 56 male; ages between 38 and 72 years) were …


The Relation Between Gleason Score, And Nuclear Size And Shape Factors In Prostatic Adenocarcinoma, Si̇bel Bektaş, Burak Bahadir, Banu Doğan Gün, Gürkan Kerti̇ş, Şükrü Oğuz Özdamar Jan 2009

The Relation Between Gleason Score, And Nuclear Size And Shape Factors In Prostatic Adenocarcinoma, Si̇bel Bektaş, Burak Bahadir, Banu Doğan Gün, Gürkan Kerti̇ş, Şükrü Oğuz Özdamar

Turkish Journal of Medical Sciences

Aim: The aim of this study was to assess the size and shape characteristics of prostatic adenocarcinoma cell nuclei using a computer-assisted analysis system, and to compare the results with the Gleason score. Materials and Methods: Morphometric nuclear parameters, such as roundness factor, form ellipse, area, length, and perimeter, were evaluated based on specimen slides of 130 prostatic adenocarcinoma cases (77% needle biopsies and 23% prostatectomy specimens) using a computerized image analysis system. Correlation analysis between Gleason score and morphometric results was performed. Results: The Gleason score was correlated with mean nuclear area (r = 0.516, P = 0.01), mean …


Prevalence Of Sen Virus Genotype-D And Genotype-H Among Haemodialysed Patients, Seda Tezcan, Nuran Deli̇ali̇oğlu, Mehmet Sami̇ Seri̇n, Gönül Aslan, Naci̇ Ti̇fti̇k, Gürol Emekdaş Jan 2009

Prevalence Of Sen Virus Genotype-D And Genotype-H Among Haemodialysed Patients, Seda Tezcan, Nuran Deli̇ali̇oğlu, Mehmet Sami̇ Seri̇n, Gönül Aslan, Naci̇ Ti̇fti̇k, Gürol Emekdaş

Turkish Journal of Medical Sciences

Aim: A recently discovered DNA virus (SEN virus) has been assumed to be responsible for post-transfusion hepatitis in humans. Phylogenetic analysis of the SEN virus (SEN-V) has revealed the existence of 8 different genotypes (A-H). SEN-V genotype-H (SENV-H) and SEN-V genotype-D (SENV-D) have been described as most closely associated with post-transfusion hepatitis. So far, it is unclear whether patients on maintenance haemodialysis are at increased risk for acquiring the SEN virus. The aim of the present study was to investigate the prevalence of SENV-D and SENV-H among patients on maintenance haemodialysis. Materials and Methods: Serum samples derived from 100 haemodialysed …


The Effect Of Music On Cognitive Emotional Response In Undergraduate Students Studying Health-Related Courses: A Pilot Study, U. Alalami, S. K. Alalami, Ross Gordon Cooper Jan 2009

The Effect Of Music On Cognitive Emotional Response In Undergraduate Students Studying Health-Related Courses: A Pilot Study, U. Alalami, S. K. Alalami, Ross Gordon Cooper

Turkish Journal of Medical Sciences

No abstract provided.


Disseminated Superficial Actinic Porokeratosis: A Case Report, Asli Eralp, Yeşi̇m Kaymak Jan 2009

Disseminated Superficial Actinic Porokeratosis: A Case Report, Asli Eralp, Yeşi̇m Kaymak

Turkish Journal of Medical Sciences

Disseminated superficial actinic porokeratosis (DSAP) is a type of porokeratosis observed in parts of the skin exposed to intense sunlight and usually appears in the third or fourth decade of life. Since it is a rare disorder, herein we present our experience of a 57-year-old man with DSAP. Dermatological examination of the patient revealed pink/red multiple papular lesions, ranging in diameter from 0.5 to 1 cm, with an atrophic center and hyperkeratotic contours limited to sun-exposed skin parts especially in the extremities and rarely in trunk. Cryotherapy was effective in healing the lesions.


Aromatase Inhibitors In Infertile Patients: Effects On Seminal Parameters, Serum And Seminal Plasma Testosterone Levels, And Estradiol Levels During Short-Term Follow-Up, M. Murad Başar, Devri̇m Tuğlu Jan 2009

Aromatase Inhibitors In Infertile Patients: Effects On Seminal Parameters, Serum And Seminal Plasma Testosterone Levels, And Estradiol Levels During Short-Term Follow-Up, M. Murad Başar, Devri̇m Tuğlu

Turkish Journal of Medical Sciences

Aim: To evaluate the effects of an aromatase inhibitor (anastrozole) on seminal parameters, and on serum and seminal plasma testosterone/estradiol ratios in infertile patients, as well as to clarify its place among empirical infertility treatment modalities. Patients and Methods: The study included 32 patients with spermatozoa numbering > 5 million/mL in ejaculate and a serum testosterone/estradiol ratio < 0.14. Anastrozole, an aromatase-inhibiting agent, was given (1 mg b.i.d.) and patients were re-evaluated 2 months later based on semen analysis, and measurements of serum and seminal plasma testosterone and estradiol levels. Results: Semen analysis parameters before and after treatment, respectively, were as follows: number of spermatozoa: 12.4 ± 4.1 million/mL and 22.3 ± 5.7 million/mL; motility: 33.4 ± 4.2% and 47.6 ± 7.4%; normal morphology: 5.4 ± 1.3% and 8.9 ± 2.7%. Differences between the values before and after treatment were statistically significant (P < 0.05). Serum testosterone level was 4.1 ± 1.2 ng/mL, estradiol level was 52.1 ± 9.4 pg/mL, and testosterone/estradiol ratio was 0.13 ± 0.03 at the beginning of treatment. These values were 3.2 ± 0.6 ng/mL, 68.4 ± 7.3 pg/mL, and 0.05 ± 0.001, respectively, in seminal plasma. Following 2 months of anastrozole treatment, testosterone and estradiol levels, and the testosterone/estradiol ratio showed statistically significant changes in serum and seminal plasma. While testosterone levels significantly increased, estradiol levels decreased (serum P_T = 0.001, P_{E2} = 0.001; seminal plasma P_T = 0.001, P_{E2} = 0.001). Conclusion: Aromatase inhibitors are a potential treatment method for infertile male patients with increased plasma estradiol levels and decreased plasma testosterone/estradiol ratios.


Comparison Of Semen Parameters Between Pregnant And Nonpregnant Couples With Male Factor Infertility During Intrauterine Insemination*, Candan İltemi̇r Duvan, Bülent Berker, Ömer Bayrak, Kaan Aydos, Ni̇lgün Turhan Öztürk, Hakan Şatiroğlu Jan 2009

Comparison Of Semen Parameters Between Pregnant And Nonpregnant Couples With Male Factor Infertility During Intrauterine Insemination*, Candan İltemi̇r Duvan, Bülent Berker, Ömer Bayrak, Kaan Aydos, Ni̇lgün Turhan Öztürk, Hakan Şatiroğlu

Turkish Journal of Medical Sciences

Aim: To compare the semen parameters between pregnant and nonpregnant couples with male factor infertility during intrauterine insemination (IUI). Materials and Methods: The study included a total of 156 IUI cycles performed in our center from January 2005 to December 2006 with the indication of male infertility. IUI cycles were divided into 2 groups: group 1 pregnancy (24 cycles) and group 2 (132 cycles) nonpregnancy cycles. Results: In both groups, progressive motility of neither initial nor processed sperm specimens was significantly different (P > 0.05). When comparisons of semen parameters in groups were performed in the initial specimen, sperm concentration and …