Digital Commons Network^™

Heterologous Expression Studies Of Saccharomyces Cerevisiae Reveal Two Distinct Trypanosomatid Caax Protease Activities And Identify Their Potential Targets, David Z. Mokry, Surya P. Manandhar, Kristen A. Chicola, George M. Santangelo, Walter K. Schmidt

Faculty Publications

The CaaX tetrapeptide motif typically directs three sequential posttranslational modifications, namely, isoprenylation, proteolysis, and carboxyl methylation. In all eukaryotic systems evaluated to date, two CaaX proteases (Rce1 and Ste24/Afc1) have been identified. Although the Trypanosoma brucei genome also encodes two putative CaaX proteases, the lack of detectable T. brucei Ste24 activity in trypanosome cell extracts has suggested that CaaX proteolytic activity within this organism is solely attributed to T. brucei Rce1 (J. R. Gillespie et al., Mol. Biochem. Parasitol. 153: 115-124. 2007). In this study, we demonstrate that both T. brucei Rce1 and T. brucei Ste24 are enzymatically active when …

Computational Fluid Dynamics Modeling Of Atmospheric Flow Applied To Wind Energy Research, Alan Russell

Boise State University Theses and Dissertations

High resolution atmospheric flow modeling using computational fluid dynamics (CFD) has many applications in the wind energy industry. A well designed model can accurately calculate wind speed, direction, and turbulence at any point in a wind farm using data from a fixed location source. The model can extend point source data over an area of several square kilometers, or map terrain influenced microclimates using remote wind data. A local flow model is critical for wind resource site assessment, and for optimizing wind farm turbine layout for maximum power production. A CFD simulation of an operating wind farm, coupled with a …

Kendall's Tau And Spearman's Rho For Zero-Inflated Data, Ronald Silva Pimentel

Dissertations

Zero-inflated continuous distributions have positive probability mass at zero in addition to a continuous distribution. Such type of data can be encountered, for example, in medical, environmental and financial research. The main focus of this research is to study the association of nonnegative random variables, both having a positive probability mass at zero. New estimators of the classical measures of association, Kendall's tau and Spearman's rho, appropriate for the zero-inflated distributions, are proposed and their asymptotic distributions are derived. Performance of the estimators is assessed by a Monte Carlo simulation study. New ideas are illustrated by a real data example.

Adoption And Integration Of Best Practice Methods In Secondary English Teaching, Gretchen Rumohr-Voskuil

Dissertations

Commencing with a critical examination of the history and rhetorical force of the term "best practice," this dissertation undertakes a qualitative study of three secondary English teachers, considering their adoption and integration of best practice methods. The subjects, represented by urban, suburban and rural secondary schools, were National Writing Project participants identified as "exemplary teachers" by a NWP site director. "Best practice" methods analyzed included the process model for the teaching of writing and literature, student decision-making, and a low-risk writing environment. Factors that were found to influence the adoption of best practice methods included undergraduate and preservice experiences, intern …

Wide I/O Dram Architecture Utilizing Proximity Communication, Qawi Ibnzayd Harvard

Boise State University Theses and Dissertations

The bandwidth and power consumption of dynamic random access memory, used as the main memory of a computer system, impacts the computer’s execution rate even with the existence of a memory hierarchy. DRAM manufacturers focus on density increases due to the innate price per bit decline of main memory while processor manufacturers continually focus on boosting performance by increasing the number of instructions completed per second. This leads to a performance gap between the microprocessor and DRAM.

Proximity communication promises to increase the I/O density of DRAM products while reducing the power consumption of the main memory system. This thesis …

Exploring Masculinities In The United States And Japan, Susan Sims Cochran

Dissertations, Theses and Capstone Projects (Full IR Collection)

This paper explores the differences and similarities between American and Japanese masculinities (and their underlying values). The paper contrasts the findings regarding American and Japanese masculinities detailed in books and articles read by the author, and discusses the portrayal of masculinities in the films "The Last Samurai," "Shall We Dance?" and "Shall We Dansu?" The paper begins with a discussion of masculinities in general, including brief historical contexts, followed by an overview of masculinities studies in America and Japan, concluding with an exploration of the similarities and differences of masculinities in America and Japan, as portrayed in the above-referenced films.

Technical Writing For Software Documentation Writers: A Textbook On Process And Product, Elizabeth Warnke

Dissertations, Theses and Capstone Projects (Full IR Collection)

No abstract provided.

Doing It Write: Professionalizing The Write Room, Joellen Kubiak-Woodall

Dissertations, Theses and Capstone Projects (Full IR Collection)

No abstract provided.

The Politics Of The Budgetary Process: The Case Study Of Georgia Perimeter College, Kimberley Robinson

Dissertations, Theses and Capstone Projects (Full IR Collection)

Given that numbers alone do not tell much of a story, this research project investigates Georgia Perimeter College’s budget process and the politics that is associated with it. This case study is an exploratory analysis. This type of methodology is ideal when a holistic, in‐depth investigation is needed. Also the method seeks to identify influences on performance. This exploratory analysis examines the comprehensive budgeting process of Georgia Perimeter College. It begins by compiling and organizing all data, and details where the budget process actually starts, who the players are in the budgeting process, and how funds are allocated. The analysis …

Northbound: An Insight Into Latino Immigrants Living In The Unites States Of America, Yahira Arizaleta

Dissertations, Theses and Capstone Projects (Full IR Collection)

No abstract provided.

Op Ed: Imhbco (In My Humble But Correct Opinion) – Academic Libraries And The “Arming America” Problem: A Response To Steve Mckinzie, Rick Anderson

Against the Grain

No abstract provided.

Implementation Of Erosion Control Warranty Specification, Bob G. Mccullouch, Kok Kuan Ng

JTRP Technical Reports

One of the main issues in a warranty specification for erosion control items is how to evaluate performance objectively. This project developed a methodology that uses digital images to measure compliance with defined vegetation cover requirements. It is designed essentially for areas where vegetation (grass) is selected as the erosion control measure. The research was a technical approach to examine the feasibility of using digital photographic analysis. It does not address all issues related to field conditions and as such would require review by interested parties to be complete. For example, how often should sample pictures to taken. Should a …

Bard Free Press, Vol. 11, No. 4 (December 2009), Bard College

Bard Free Press - All Issues (2000-2018)

No abstract provided.

The Bg News December 1, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. December 1, 2009. Volume 100-Issue 65.

On The Many Flavors Of Capitalism Or Reflections On Schumpeter's Ghost, John Henry Schlegel

Journal Articles

Most legal scholars treat capitalism as a genus with one species. The appearance of several books that argue to the contrary suggests that it is sensible to revisit this assumption. Discussion begins by considering the constructed nature of markets, the importance of market systems, and the role of financings as the factor distinguishing capitalism from other forms of a market economy. Thereafter, four articulations of the varieties of capitalism are reviewed: the classic Marxist one, one by a political economist, another by a pair of comparative political scientists, and third by a trio of economists. This review leads to a …

Risk Matrix Input Data Biases, Eric D. Smith, William T. Siefert, David Drain

Engineering Management and Systems Engineering Faculty Research & Creative Works

Risk matrices used in industry characterize particular risks in terms of the likelihood of occurrence, and the consequence of the actualized risk. Human cognitive bias research led by Daniel Kahneman and Amos Tversky exposed systematic translations of objective probability and value as judged by human subjects. Applying these translations to the risk matrix allows the formation of statistical hypotheses of risk point placement biases. Industry-generated risk matrix data reveals evidence of biases in the judgment of likelihood and consequence-principally, likelihood centering, a systematic increase in consequence, and a diagonal bias. Statistical analyses are conducted with linear regression, normal distribution fitting, …

Forecasting Science And Technology For The Department Of Defense, John W. Lyons, Richard Chait, James J. Valdes

Defense and Technology Papers

This paper discusses recent trends in S&T, particularly how various disciplines have converged to produce new capabilities, and considers how a new series of studies might be conducted taking into account such convergences.

Vol. 1 No. 1, Fall 2009; Current Trends In Inequitable Conduct Are Adverse To Patent Policy As Seen Through The Exemplary Case Of Big Pharma, Joshua M. Austin

Northern Illinois Law Review Supplement

This Comment explores the rather difficult and rapidly changing field of patent law, discussing specifically the doctrine of inequitable conduct, a defense raised by the infringing party by which a patent can be rendered unenforceable. Recent trends in inequitable conduct, as it has been used by the Federal Circuit, have made this confusing area of law even more so. This comment identifies these confusions and the Federal Circuit's failure to maintain clear cut precedent. This Comment further discusses the impacts of these current trends, postulating that these trends go so far as to undercut the principal policy purposes behind patent …

Space-Efficient Framework For Top-K String Retrieval Problems, Wing Kai Hon, Rahul Shah, Jeffrey Scott Vitter

Faculty Publications

Given a set D = {d1,d2, ⋯, dD} of D strings of total length n, our task is to report the "most relevant" strings for a given query pattern P. This involves somewhat more advanced query functionality than the usual pattern matching, as some notion of "most relevant" is involved. In information retrieval literature, this task is best achieved by using inverted indexes. However, inverted indexes work only for some predefined set of patterns. In the pattern matching community, the most popular pattern-matching data structures are suffix trees and suffix arrays. However, a typical suffix tree search involves going through …

Effects Of Aggregate Angularity On Mix Design Characteristics And Pavement Performance, Leonardo T. Souza, Yong-Rak Kim

Nebraska Department of Transportation: Research Reports

No abstract provided.

Effects Of Aggregate Angularity On Mix Design Characteristics And Pavement Performance, Yong-Rak Kim, Leonardo T. Souza

Nebraska Department of Transportation: Research Reports

This research targeted two primary purposes: to estimate current aggregate angularity test methods and to evaluate current aggregate angularity requirements in the Nebraska asphalt mixture/pavement specification. To meet the first research objective, various aggregate angularity tests were estimated with the same sets of aggregates and were compared by investigating their characteristics on testing repeatability, cost, testing time, workability, and sensitivity of test results. For the second objective, the effect of aggregate angularity on mixture performance was investigated by conducting laboratory performance tests (the uniaxial static creep test and the indirect tensile fracture energy test) of five mixes designed with different …

Deliberative Democracy And Inequality: Two Cheers For Enclave Deliberation Among The Disempowered, Christopher F. Karpowitz, Chad Raphael, Allen S. Hammond Iv

Communication

Deliberative democracy grounds its legitimacy largely in the ability of speakers to participate on equal terms. Yet theorists and practitioners have struggled with how to establish deliberative equality in the face of stark differences of power in liberal democracies. Designers of innovative civic forums for deliberation often aim to neutralize inequities among participants through proportional inclusion of disempowered speakers and discourses. In contrast, others argue that democratic equality is best achieved when disempowered groups deliberate in their own enclaves (interest groups, parties, and movements) before entering the broader public sphere. Borrowing from each perspective, the authors argue that there are …

Star–Tides And Starfish Networks: Supporting Stressed Populations With Distributed Talent, Linton Wells Ii, Walker Hardy, Vinay Gupta, Daniel Noon

Defense Horizons

The Department of Defense increasingly is involved in postwar stabilization and reconstruction, humanitarian assistance and disaster relief missions, capacity-building of partner nations at home and abroad, and other such complex operations. To provide sustainable support to stressed populations in these environments, an international, networked, knowledge-sharing research project called Sustainable Technologies, Accelerated Research–Transformative Innovation for Development and Emergency Support (STAR–TIDES)¹ encourages innovative approaches to public-private collaboration, whole-of-government solutions, and transnational engagement. It leverages a distributed network of people and organizations to conduct research, support real world contingencies, and bridge gaps among disparate communities.

Pharmaceutical Direct-To-Consumer Advertising And Print Media, Vanessa Khim

Graphic Communication

The purpose of this study was to determine which type of pharmaceutical direct-to-consumer (DTC) advertising would be the best marketing strategy for pharmaceutical companies to use. The main argument was that one-to-one marketing in the forms of print media and the Internet was the best strategy over mass media marketing in the forms of television and radio.

The study researched various literary sources on the different marketing strategies which facilitated in examining the positive and negative aspects of each. One hundred surveys were distributed to medical personnel and pharmaceutical prescription consumers in both the Bay Area and San Luis Obispo …

Comparison Of Eye Movement Data To Direct Measures Of Situation Awareness For Development Of A Novel Measurement Technique In Dynamic, Uncontrolled Test Environments, Kristin Moore

All Dissertations

Situation awareness (SA) is a measure of an individual's knowledge and understanding of the current and expected future states of a situation. While there are numerous options for SA measurement, none are currently suitable in dynamic, uncontrolled environments. Direct measures of SA are the most common, but require a large amount of researcher control as well as the ability to stop operators during a task in order to ask questions about their levels of SA. The current research explored the relationship between direct measures of SA and eye tracking measures as a first step in the development of an unobtrusive …

Bridging The Operational Divide: An Information-Processing Model Of Internal Supply Chain Integration, Ana Rosado Feger

All Dissertations

Supply Chain Management, the coordination of upstream and downstream flows of product, services, finances, and information from a source to a customer, has risen in prominence over the past fifteen years. The delivery of a product to the consumer is a complex process requiring action from several independent entities. An individual firm consists of multiple functional departments, each responsible for one aspect of customer service. In the traditional corporate structure of functional silos, there is little communication between Purchasing, Manufacturing, and Logistics, and yet these departments comprise three core supply chain processes of a firm. Ironically, managers report that it …

Reaching Beyond The "Moron": Eugenic Control Of Secondary Disability Groups, Gerald V. O'Brien, Meghan E. Bundy

The Journal of Sociology & Social Welfare

While much has been published about the American eugenics movement, few authors have considered the relative status of various disability populations as targets of eugenic control. While many writers focus on persons diagnosed as feeble-minded as the central focus of control, little has been written regarding the status of additional disability groups. This is important since, as described here, a central component of coming to understand past social injustices against marginalized groups and the contemporary relevance of such injustices is gaining an awareness of why specific populations were accepted by control authorities as appropriate or viable targets for control measures.

Two-Phase Boost Converter, Tadeus Gunawan

Master's Theses

A boost converter is one of the most efficient techniques to step up DC input voltage to a higher needed DC output voltage. The boost converter has many possible applications, such as in a photovoltaic system, hybrid car and battery charger. The proposed prototype in this report is a proof of concept that a Two-Phase Boost Converter is a possible improvement topology to offer higher efficiency without compromising any advantages readily offered by a basic boost. The prototype is designed to be able to handle up to 200 watts of output power with an input of 36 volts and an …

Single Cell Impedance Measurements Using Microfabricated Electrodes And Labview Graphical Programming, Stephanie Sophia Hernandez

Master's Theses

This Master’s Thesis project consists of the research, design, and fabrication of a system that could perform broadband impedance measurements (1kHz-20Mhz) of single cells using National Instruments Labview data acquisition and programming in coordination with a single cell capture device. Presented first is the background information on cells and their electrical properties, along with background in micro-total-analysis systems as well as impedance spectroscopy. Experimental Methods are then discussed for the electrode design, cellular modeling in COMSOL, fabrication methods, and Labview 8.0 Set-up and programming. Measurements were performed using the single-cell capture device on saline, yeast cells, and a polysterene bead. …

Cross-Border Banking: The Road Ahead And Lessons From Emerging Markets In Europe, David Nellor, Salinas Gonzalo

Economic and Financial Review

This paper focuses on the regulatory challenges posed by the growth of cross-border banking, lessons from the emerging markets in Europe. It also highlights that authorities in sub-Sahara Africa, and Nigeria, in particular, could draw from European experience.