Digital Commons Network^™

Nitric Oxide Inhibits Insulin-Degrading Enzyme Activity And Function Through S-Nitrosylation, Crystal M. Cordes, Robert G. Bennett, Gerri L. Siford, Frederick G. Hamel

United States Public Health Resources

Insulin-degrading enzyme (IDE) is responsible for the degradation of a number of hormones and peptides, including insulin and amyloid β (Aβ). Genetic studies have linked IDE to both type 2 diabetes and Alzheimer’s disease. Despite its potential importance in these diseases, relatively little is known about the factors that regulate the activity and function of IDE. Protein S-nitrosylation is now recognized as a redox-dependent, cGMP-independent signaling component that mediates a variety of actions of nitric oxide (NO). Here we describe a mechanism of inactivation of IDE by NO. NO donors decreased both insulin and Aβ degrading activities of IDE. Insulin-degrading …

Proteomics Reveal A Concerted Upregulation Of Methionine Metabolic Pathway Enzymes, And Downregulation Of Carbonic Anhydrase-Iii, In Betaine Supplemented Ethanol-Fed Rats, Kusum K. Kharbanda, Vasanthy Vigneswara, Benita L. Mcvicker, Anna U. Newlaczyl, Kevin Bailey, Dean Tuma, David E. Ray, Wayne G. Carter

United States Public Health Resources

We employed a proteomic profiling strategy to examine the effects of ethanol and betaine diet supplementation on major liver protein level changes. Male Wistar rats were fed control, ethanol or betaine supplemented diets for 4 weeks. Livers were removed and liver cytosolic proteins resolved by onedimensional and two-dimensional separation techniques. Significant upregulation of betaine homocysteine methyltransferase-1, methionine adenosyl transferase-1, and glycine N-methyltransferase were the most visually prominent protein changes observed in livers of rats fed the betaine supplemented ethanol diet. We hypothesise that this concerted upregulation of these methionine metabolic pathway enzymes is the protective mechanism by which betaine restores …

Identification Of Francisella Tularensis Subsp. Tularensis A1 And A2 Infections By Real-Time Polymerase Chain Reaction, Claudia R. Molins, Jennifer K. Carlson, Jana Coombs, Jeannine M. Petersen

United States Public Health Resources

Francisella tularensis subsp. tularensis (type A) is subdivided into clades A1 and A2. Human tularemia infections caused by A1 and A2 differ with respect to clinical outcome; A1 infections are associated with a higher case fatality rate. In this study, we develop and evaluate TaqMan polymerase chain reaction (PCR) assays for identification of A1 and A2. Both assays were shown to be specific to either A1 or A2, with sensitivities of 10 genomic equivalents. Real-time PCR results for identification of A1 and A2 were in complete agreement with results obtained by pulsed field gel electrophoresis analysis or conventional PCR when …

Annual Report 2008-2009, Houston Academy Of Medicine-Texas Medical Center Library

Annual Reports: 1943 - Present

This file contains the Annual Report for the library from 2008-2009.

Suffolk Alumni Magazine, Vol. 4, No. 3, 2009, Suffolk University

Suffolk University Magazine

No abstract provided.

Suffolk Alumni Magazine, Vol. 4, No. 2, 2009, Suffolk University

Suffolk University Magazine

No abstract provided.

The Mobility Impact: Implications And Solutions For Families On The Move With An Original Book For Children., Sarah Willis

Graduate Student Independent Studies

Examines the relationship between student mobility and achievement. Contains a picture book for children four to six years designed to help with the transition from house or neighborhood into a new one. Includes recommendations for ways families and schools can help children with the moving process.

Adaptive Leadership: Leadership Theory Or Theoretical Derivative?, Bill Cojocar

Academic Leadership: The Online Journal (2003-2012)

Today’s public and private business leaders and leaders of our Armed Forces are faced with challenges that require leadership that is capable of tackling and solving complex problems and issues, with collective, collaborative, timely effective, and innovative solutions. This set of challenges requires leadership that spans the spectrum of leadership theories, traits, and stylistic approaches that is very adaptive, yet direct in nature. This type of leadership is defined as ‘adaptive leadership’ and is a style of leadership that is developing into a new theory of its own, evolving from situational, transformational, contingency, and complexity theories, as described by Nastanski, …

A 360° View Of Non-Traditional University Presidents, Daryl Delabbio, Louann Palmer

Academic Leadership: The Online Journal (2003-2012)

Institutions of higher learning continue to face many challenges, from declining revenues and increased costs (Fain, 2008) to lack of confidence in their ability to meet the needs of the students and the society they serve (Smith, 2004). At the center of the institution is its CEO: the president. It is in this office and at this person that the buck stops. It is here where decisions are made that will affect the institution and all of its constituencies. As the literal and symbolic leader, the vitality of a given institution is dependent upon the effectiveness of its president (Rhodes, …

The Medical And Social Impact Of Cholera In The 19th Century And Beyond, Heather Guy

Vulcan Historical Review

pp. 71-84

Using John Wilders To Teach Shakespeare’S Second Tetralogy, Edmund M. Taft

Quidditas

John Wilders. The Lost Garden: A View of Shakespeare’s English and Roman History Plays. Totowa, NJ: Rowman & Littlefield, 1978. 154 pp.

“O thoughts of men accurst!

Past and to come seems best; things present, worst.”

(2 Henry 4.1.3.107-108)

Becoming Literate Through Art: Benefits Of A Literacy Infused Art Curriculum, Amy Wagner

Theses and Graduate Projects

The decline of literacy skills continues to be a crisis and a concern. It is important to emphasize that being literate goes beyond reading and writing. The definition of literacy can and should also include the ability to listen and speak. With this inclusion literacy becomes well defined as a form of communication. While art and writing are both forms of expression and thereby a means of communication, it is only natural that, because the two share the same goal, they should be studied jointly. The study and practice of art can enhance student's fine motor skills, cognitive learning development …

Limits And Challenges Of E-Mail Use In The Business World, Joanne L. Johnson

Theses and Graduate Projects

Miscommunication can cost time, money and even relationships. Facts surrounding e-mail's speed, convenience, and cost-effectiveness have been established; however, through my research and experience I have discovered there are limits to the effectiveness of e-mail. I will discuss the limitations of e-mail as a medium for effective business communication from the perspective of its effectiveness as a medium,, effects on productivity, and possible risks. E-mail poses limits and challenges as a communication medium in the business world versus basic face-to-face communication. The absence of non-verbal and verbal cues and the ability in standard e-mail for immediate feedback are weaknesses. As …

Teaming: Advantages And Implementation, Kevin Van Gheem

Theses and Graduate Projects

Teaching for four years, I have first-hand experience of what it is like teaching in two distinctly different types of classrooms. My first year was difficult as I was often alone in my room with little guidance or help from fellow teachers. The following three years, our school began to implement teaming and I began to see the benefits of it right before my eyes. This paper will examine some of the benefits for students, parents, and teachers. It will also discuss different types of teams or professional learning communities that can exist in a school. And finally, this paper …

2009 Intersession Catalog, Illinois Mathematics And Science Academy

Intersession Catalogs

No abstract provided.

Richard Newhauser (Ed.), The Seven Deadly Sins: From Communities To Individuals (Book Review), Denise A. Kaiser

History Faculty Publications

Book review by Denise Kaiser:

ISBN 9789004157859

Advocates For Agriculture: Discovering Your Influential Power, Troy Hadrick, Stacy Hadrick

Range Beef Cow Symposium

One doesn’t have to watch any type of media source for very long these days to come across a story that is very negative towards agriculture. Specifically, animal agriculture has become a favorite target for many reporters, animal rights groups, and even some consumers. It seems that many of them chose not to even include the thoughts of actual farmers and ranchers when talking about agriculture. Instead they turn to the internet or other non-ag sources for their information. So with so much negative attention being placed on food production, what do we do as producers to combat this situation? …

Animal Rights As A Mainstream Phenomenon [Shortened Version For Reading In Australia], Bernard E. Rollin

Range Beef Cow Symposium

The last 50 years have witnessed a dazzling array of social ethical revolutions in Western society. Such moral movements as feminism, civil rights, environmentalism, affirmative action, consumer advocacy, pro- and anti-abortion activism, homosexual rights, children‘s rights, the student movement, antiwar activism, public rejection of biotechnology, have forever changed the way governments and pubic institutions comport themselves. This is equally true for private enterprise: to be successful, businesses must be seen as operating solidly in harmony with changing and emerging social ethics. It is arguable that morally based boycotting of South African business was instrumental in bringing about the end of …

Extensive Heifer Development Systems, Richard N. Funston, Jeremy Martin, Andy Roberts

Range Beef Cow Symposium

Studies in numerous species provide evidence that diet during development can partially control physiological changes necessary for puberty (Frisch, 1984). Energy balance or plane of nutrition influences reproductive performance in heifers and cows (Butler and Smith, 1989; Randel, 1990; Robinson, 1990; Short and Adams, 1988; Swanson, 1989). Numerous studies have reported inverse correlations between postweaning growth rate and age at puberty (Arije and Wiltbank, 1971; Ferrell, 1982; Short and Bellows, 1971; Wiltbank et al., 1966, 1969, 1985) and pregnancy rates in heifers were shown to be dependent upon the number displaying estrus prior to or early in the breeding season …

Common $Ense Heifer Management, Patsy Houghton

Range Beef Cow Symposium

The replacement heifer is a mixed blessing for cow-calf operators. On one hand, she represents the future profitability and genetic improvement of the cow herd; thus her selection and development are of paramount importance to the continued success of any cow herd. On the other hand, the replacement heifer is an inconvenience at best. She is essentially non-productive for the first two-and-a-half years of her life; thus she places a significant drain on a rancher’s cash flow, making her easy prey for mismanagement. Nevertheless, proper growth and development of the replacement female from birth until she produces her first calf …

Impact Of Method Of Heifer Development And Post-Ai Management On Reproductive Efficiency, George Perry, Julie Walker, Cody Wright, Ken Olson

Range Beef Cow Symposium

An important part of any production system is the reproductive performance and costs associated with developing replacement heifers. The cost of developing replacement heifers has a tremendous impact on the profitability and sustainability of cow-calf operations, and reproductive failure costs the U.S. beef and dairy industries approximately $1 billion annually (Bellows et al., 2002). Heifers need to calve by 24 months of age to achieve maximum life-time productivity (Patterson et al., 1992), and heifers that lose a pregnancy or conceive late in the breeding season are likely to not have enough time to rebreed during a defined breeding season. In …

Profitable Cow And Heifer Pregnancy Rates, Jack C. Whittier

Range Beef Cow Symposium

Wow! What a challenging topic. Why is it challenging? Because there is not one right answer; nor is the question easy to define or analyze. However, there are some underlying principles that I believe apply in most situations. I will spend most of my time on those principles with the hope that you as a cattle manager can use these principles to make good decisions.

Integrating Information Into Selection, Connee R. Quinn

Range Beef Cow Symposium

Integration: To make into a whole by bringing all parts together. As ranchers we intuitively know the unique resources that make up the whole of our operations and use these resources to cost effectively produce a product. Ranch resources can be simply categorized into forage, genetics and people and the rancher‘s commitment to good management practices. Add to that, information or knowledge management, management of relationships and, of course, managing for the end product. The glue that holds these parts together is the rancher-- the heart, the passion of the operation.

Integrating Information Into Selection, Loren Berger

Range Beef Cow Symposium

Berger’s Herdmasters is located on the southern edge of the Sandhills near North Platte, Nebraska and is home to our composite seedstock operation with a base of approximately 350 head. Our business is focused on the production of hybrid bulls consisting of Red Angus X Simmental and Angus X Simmental, plus we do have some high percentage Angus bulls (both Red and Black) that are designed to be used on heifers. Our operation conducts an annual bull sale on the second Saturday in February and continues to see expansion each year. This year’s offering will consist of around 180 bulls …

New Beef Products Research, Chris R. Calkins

Range Beef Cow Symposium

Muscle profiling research conducted in the early part of this decade by the University of Nebraska and the University of Florida for The Beef Checkoff was highly successfully. This research led to the development of the flat iron steak, the petite tender, and the ranch cut from the shoulder clod and has been credited with increasing the value of market cattle by $50 - $70 per head. In 2007, over 92 million pounds of flat iron steaks, 40 million pounds of petite tenders, and 37 million pounds of ranch steaks were sold into foodservice. Although difficult to track, additional sales …

Selecting For Efficiency, Nick Hammett

Range Beef Cow Symposium

Why is efficiency so important to the beef industry? "Efficiency impacts unit cost of production, thereby having the potential to increase beef's competitiveness in both the domestic and global marketplace, to improve industry profitability, and to enhance long-term sustainability of the industry." (Ritchie, 2001). In simple terms, from a producer’s standpoint, efficiency can make you more money by lowering costs, increasing returns, or both. But, only if measured, interpreted and implemented correctly.

Impacts Of Calf Nutritional Management On Quality Grade, Scott Lake

Range Beef Cow Symposium

Why is quality important? An enormous amount of research and money have been invested in determining the impacts of just about every management practice on the effects of marbling. Marketing and management practices have been developed around the choice/select spread. But the question begs to be asked, “Is marbling important?” Regardless of the choice/select spread or any other premiums received due to carcass quality, the answer to that question should be a resounding “YES”, for no other reason than the importance of a quality eating experience from consumers. The 2005 National Quality Beef Audit reports that the #1 concern of …

Managing Annual Bromes In The Northern Great Plains, Lance Vermeire, Matt Rinella, Jennifer Muscha

Range Beef Cow Symposium

Annual bromes periodically have substantial impact on rangelands in the northern Great Plains. The often rapid increases in annual brome populations and there negative effects on forage and animal production are justified cause for concern. However, population increases are predictable and management tools have been successfully identified for short-term control. Fort Keogh Livestock and Range Research Laboratory is examining new applications of established methods and testing whether careful timing and integration of control methods may be key to long-term reduction of annual bromes.

The Two Best Decisions I Have Made, John Maddox

Range Beef Cow Symposium

You might be surprised when I tell you the two best decisions made on our ranch, are much easier to come up with than the two worst decisions. Now, not even for a second, do I believe that I haven’t made some big mistakes. A matter of fact some of them have been real dousies. And there have been so many big mistakes somehow prioritizing them in order to come up with two of the worst is not only difficult but they are painful to recollect! So lets start with the best decisions.

U.S. Beef Demand Drivers And Enhancement Opportunities: A Research Summary, James R. Mintert, Glynn T. Tonsor, Ted C. Schroeder

Range Beef Cow Symposium

Large shifts in domestic beef demand have had substantial impacts on the beef industry. Before the late 1970s, growth in the U.S. economy and rising consumer incomes contributed to beef demand increasing for a sustained period. In response to growing product demand, the beef industry increased in size. However, starting about 1980, domestic retail beef demand weakened and subsequently declined every year through 1998. The long-run decline in retail beef demand contributed to a reduction in cattle industry size, particularly in relation to competing meat sectors such as poultry and pork. In 1999, following nearly 20 consecutive years of decline, …