Digital Commons Network^™

Esquivel V. State Respondent's Brief Dckt. 35792

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Cannabinoid Receptor Type 2 Activation Induces A Microglial Anti-Inflammatory Phenotype And Reduces Migration Via Mkp Induction And Erk Dephosphorylation, Edgar A. Romero-Sandoval, Ryan Horvath, Russell P. Landry, Joyce A. Deleo

Dartmouth Scholarship

Cannabinoid receptor type 2 (CBR2) inhibits microglial reactivity through a molecular mechanism yet to be elucidated. We hypothesized that CBR2 activation induces an anti-inflammatory phenotype in microglia by inhibiting extracellular signal-regulated kinase (ERK) pathway, via mitogen-activated protein kinase-phosphatase (MKP) induction. MKPs regulate mitogen activated protein kinases, but their role in the modulation of microglial phenotype is not fully understood.

May 27, 2009 Greenmail, University Of Alabama At Birmingham

GreenMail (student newsletter through 2024)

No abstract provided.

Spectator 2009-05-27, Editors Of The Spectator

The Spectator

No abstract provided.

Adenylyl Cyclases 1 And 8 Initiate A Presynaptic Homeostatic Response To Ethanol Treatment, Alana C. Conti, James W. Maas Jr., Krista L. Moulder, Xiaoping Jiang, Bhumy A. Dave, Steven Mennerick, Louis J. Muglia

Neurosurgery Faculty Publications

Background: Although ethanol exerts widespread action in the brain, only recently has progress been made in understanding the specific events occurring at the synapse during ethanol exposure. Mice deficient in the calciumstimulated adenylyl cyclases, AC1 and AC8 (DKO), demonstrate increased sedation duration and impaired phosphorylation by protein kinase A (PKA) following acute ethanol treatment. While not direct targets for ethanol, we hypothesize that these cyclases initiate a homeostatic presynaptic response by PKA to reactivate neurons from ethanol-mediated inhibition. Methodology/Principal Findings: Here, we have used phosphoproteomic techniques and identified several presynaptic proteins that are phosphorylated in the brains of wild type …

The Alestle - Vol. 61 No. 64 - 05/27/2009, Southern Illinois University Edwardsville

The Alestle

Vol. 61 No. 64

Characterization Of Agricultural Runoff Associated With Proagritm Treatment Of Poultry Litter Added To Soils, Chrissy Harris

Student Theses and Dissertations

One of the greatest problems facing crop producers, who utilize poultry litter as a fertilizer for their fields, is phosphorus (P) runoff. Although phosphorus is a necessary element for optimal crop production, it can also have an adverse reaction when introduced into the aquatic environment. This problem is thought to have been helped by a new litter treatment product, ProAgriTM that became available for use in the poultry houses, which allegedly binds up the excess P. The purpose of this study was to examine the effect of the ProAgriTM on water quality of runoff. Four different treatments which included a …

The Bg News May 27, 2009, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. May 27, 2009. Volume 99-Issue 152.

Structural Polarities In J.R.R. Tolkien's The Lord Of The Rings, Quincey Vierling Upshaw

USF Tampa Graduate Theses and Dissertations

My thesis reflects an assessment of The Lord of the Rings centering on the idea of a structure of opposites. For each place, race, character and object in The Lord of the Rings, J.R.R. Tolkien included an element which serves as an antithesis. In addition, the style, pacing, and language of the work also contain antithetical pairs which continually engage and propel the reader to the work's conclusion. I contend that this deliberate pairing of opposing elements adds depth and verisimilitude to the work.

Tolkien was an avid student of what his contemporaries would have called "fantasy" or "fairy …

Bringing Students’ Culture Into An Esl/Efl Classroom, Moodiela Mathobela

Sandanona

Can there be an empowering and successful language teaching and learning without incorporating students' culture and their immediate life experiences? Participants and the presenter will experience, explore, and reflect on how students' culture could be used to affect successful learning and vindicate the saying, 'nothing about us without us'.

Adebaran Vol. 3, Issue 2

Aldebaran

No abstract provided.

As-685-09 Resolution On Proposal To Establish College Of Agriculture, Food And Environmental Sciences (Cafes) Center For Sustainability, College Of Agriculture, Food And Environmental Sciences

Academic Senate Resolutions

Endorses the proposal to establish a CAFES Center for Sustainability.

Florida Sentinel Bulletin, May 26, 2009, Gwen Hayes

Florida Sentinel Bulletin Collection

The May 26, 2009, issue of the Florida Sentinel Bulletin.

Similar Patterns Of Linkage Disequilibrium And Nucleotide Diversity In Native And Introduced Populations Of The Pea Aphid, Acyrthosiphon Pisum, Jennifer A. Brisson, Sergey V. Nuzhdin, David L. Stern

School of Biological Sciences: Faculty Publications

Background: The pea aphid, Acyrthosiphon pisum, is an emerging genomic model system for studies of polyphenisms, bacterial symbioses, host-plant specialization, and the vectoring of plant viruses. Here we provide estimates of nucleotide diversity and linkage disequilibrium (LD) in native (European) and introduced (United States) populations of the pea aphid. Because introductions can cause population bottlenecks, we hypothesized that U.S. populations harbor lower levels of nucleotide diversity and higher levels of LD than native populations. Results: We sampled four non-coding loci from 24 unique aphid clones from the U. S. (12 from New York and 12 from California) and 24 …

Academic Senate - Agenda, 5/26/2009, Academic Senate

Academic Senate Agendas

No abstract provided.

Hotline Press Newspaper- May 26,2009 Vol 26 No 49, Hotline Press Newspaper

Hotline Press Newspaper 2009

No abstract provided.

“Design And Synthesis Of Molecular Probes For The Study Of 5-Ht2a And H1 Receptors”, Jitesh Shah

Theses and Dissertations

The serotonin (5-HT) receptors, with seven subtypes and at least fifteen distinct members, mediate a wide range of physiological functions both in the central nervous system and in the periphery. All members of the 5-HT family except the 5-HT3 subtype belong to the family of aminergic G protein-coupled receptors (GPCRs). Over the years, various molecules have been reported which act selectively at 5-HT2 receptors. However, there are no ligands that exhibit complete selectivity for one subpopulation of 5-HT2 receptors. Insight into how drugs bind to 5-HT2 receptors could contribute significantly to the development of subtype-selective agents with enhanced therapeutic effects. …

David Engel And "The Oven Bird's Song" (Edited Interview), David M. Engel

Contributions to Books

Published as Chapter 8 in Conducting Law and Society Research: Reflections on Methods and Practice, Simon Halliday & Patrick Schmidt, eds.

Understanding litigiousness involves many perspectives on how societies generate, shape, and process disputes. Whereas some may begin the study of disputing with the law and the formal institutions charged with implementing it, or what happens “in court,” a long tradition of Law and Society scholarship has emphasized the importance of seeing how cultural practices give life and meaning to the law. Though some of this scholarship has come from anthropology, much of it has been produced by scholars from …

Development Of Ppar-Γ Receptor Agonists As Therapeutic Agents For Diabetes, Ashwini Goswami

Theses and Dissertations

The peroxisome proliferator-activated receptors (PPARs) are the transcriptional regulators of glucose, lipids and cholesterol metabolisms. It has been established that PPAR-γ is the receptor for thiazolidinediones (TZDs) class of type II anti-diabetic drugs. These compounds act as agonists of PPAR-γ. They may delay the development of type II diabetes in individuals at high risk of developing the condition, and have been shown to have potentially beneficial effects on cardiovascular risk factors. PPAR-γ receptor activation by TZDs improves insulin sensitivity by promoting fatty acid uptake into adipose tissue, increasing production of adiponectin (responsible for glucose regulation and fatty acid metabolism) and …

To Flee Or To Fight, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

A New Quantitative Method For The Taxonomic Identification Of Tetrapods, Stephanie Kuster

All Theses and Dissertations (ETDs)

The rarity of good fossil samples throughout geologic time frequently makes fossil identification difficult. This dissertation presents a new, multivariate, statistically validated method to identify tetrapods based on quantification of the shapes of microstructural features in cortical bone of the postcranial skeleton. The ultimate goal is to reduce the reliance on rare, near-complete fossil skeletons. The method is validated on a set of 15,745 mammalian microstructural features from eleven diverse species. An additional set of 21,122 microstructural features from one species serve to examine microstructural variation within a single skeleton. Microstructural measurements were made on thin-sections using optical microscopy. Initial …

Uropathogenic E. Coli Employ A Conserved Intracellular Infection Pathway That Can Be Inhibited By Novel Anti-Virulence Therapeutics, Corinne Cusumano

All Theses and Dissertations (ETDs)

Urinary tract infections: UTIs) affect 13 million women annually in the United States and are predominately caused by uropathogenic Escherichia coli: UPEC). In a murine cystitis model, UPEC utilize a multistep pathogenic pathway in which they invade and form intracellular bacterial communities: IBCs) within bladder facet cells. Type 1 pili expressing the adhesin, FimH, are necessary for UPEC binding and invasion of urothelial cells and formation of IBCs. UPEC ultimately disperse from the IBC, many with filamentous morphology, and infect other host urothelial cells. Using a panel of UPEC clinical isolates, this work evaluates the conservation of the IBC pathway …

Evaluation Of Pbr In Breast Cancer, Stephany Shockley

All Theses and Dissertations (ETDs)

The utility of Positron Emission Tomography: PET) in the detection of cancer began with the radiopharmaceutical 2-[18F]fluoro-2-deoxyglucose: FDG) used for measuring altered cellular metabolism. Specific radioligands are being developed to allow non-invasive analysis of protein expression to further characterize tumors. One protein that has been identified as a promising target is the Peripheral Benzodiazepine Receptor: PBR). PBR expression is up-regulated in several cancers, and in many there has been a correlation drawn between increased malignancy and protein expression levels. Therefore, developing PET methodologies to apply for PBR imaging could be an important step in understanding individual tumors as we move …

Growth Factor Delivery From Fibrin Matrics Containing Affinity-Based Delivery Systems To Treat Peripheral Nerve Injury, Matthew Wood

All Theses and Dissertations (ETDs)

This thesis work sought to develop a biomaterial to further the understanding of affinity-based delivery and to serve as a potential treatment for peripheral nerve injury. The use of an affinity-based delivery system: ABDS) with growth factors in a nerve guidance conduit: NGC) was hypothesized to promote nerve regeneration and functional recovery following a critical nerve defect. Evaluation of affinity-based delivery using peptides with varying binding affinity for heparin determined that peptide binding affinity for heparin affected the release rate and biological activity of nerve growth factor: NGF) in vitro. The ABDS presented biologically active NGF, which promoted neurite extension …

Dissecting The Molecular Mechanisms Underlying Synpase Development And Neuronal Functions In Caenorhabditis Elegans, Shuo Luo

All Theses and Dissertations (ETDs)

The development and function of the nervous system is under delicate regulation of diverse tissue-derived signals in multi-cellular organisms. In Dr. Nonet's lab, I am using the model organism Caenorhabditis elegans to ask two basic questions: 1) How do different tissues in an organism coordinate to regulate neural functions and behaviors? 2) What controls the development of synapse, the basic unit of the nervous system? These questions divide my dissertation into three parts, with the first two parts related to the first question and the third part to the second question. In the first part of this dissertation, I present …

May 23, 2009 (Pages 2559-2678), Pennsylvania Legislative Reference Bureau

Volume 39 (2009)

No abstract provided.

Assuring Quality In Distance Education For Library And Information Science: The Role Of The Library, V Gopkumar, A Baradol

Library Philosophy and Practice (e-journal)

The concept of distance education and its use in Library and Information Science (LIS) education are presented. The importance of providing library and information services for LIS distance learners to enhance quality is discussed. The paper points out that web based information services can be used to extend library and information services to distance learners. Options and resources available are discussed in detail. A way of re-engineering of library and information services is highlighted.

Florida Sentinel Bulletin, May 22, 2009, Gwen Hayes

Florida Sentinel Bulletin Collection

The May 22, 2009, issue of the Florida Sentinel Bulletin.

Volume Cxxvi, Number 24, May 22, 2009, Lawrence University

The Lawrentian

No abstract provided.

Moarabisque: The Essence Of Arabia : A Motion Graphics Piece That Promotes The Diverse Saudi Arabian Arts And Culture, Wail Al Hamid

Theses

Moarabisque: The essence of Arabia is an "Arabian custom designed motion graphics series". This Series is inspired by the diverse geography, architecture, arts, and culture of the Arabian Peninsula. These series are merged together as a cohesive motion graphics piece that visually reflects and promotes the varied Arabian culture through arts, architecture, music, and Islamic iconography. The final motion graphics video will introduce a series of visual icons that are of vital importance to religious and cultural values of Muslims; especially the Arabic nation. These icons delineate the characteristics of the Arabian culture; an Islamic civilized culture that emerged from …