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2009

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Characterization Of Ligand-Induced Conformational Changes In The Egf Receptor, Katherine Yang Jan 2009

Characterization Of Ligand-Induced Conformational Changes In The Egf Receptor, Katherine Yang

All Theses and Dissertations (ETDs)

ABSTRACT OF DISSERTATION Characterization of ligand-induced conformational changes in the EGF receptor by Katherine S. Yang Doctor of Philosophy in Biochemistry Washington University in St. Louis, 2009 Professor Linda Pike, Chairperson The epidermal growth factor: EGF) receptor is a classical receptor tyrosine kinase that mediates cellular processes such as proliferation, migration, and differentiation in response to growth factor stimulation. Crystal structures of the EGF receptor suggest that its activation is associated with extensive conformational changes in both the extracellular and intracellular domains. However, evidence of these structural dynamics in intact cells has been lacking. This thesis describes the characterization of …

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Development And Implementation Of Fully 3d Statistical Image Reconstruction Algorithms For Helical Ct And Half-Ring Pet Insert System, Daniel Keesing Jan 2009

Development And Implementation Of Fully 3d Statistical Image Reconstruction Algorithms For Helical Ct And Half-Ring Pet Insert System, Daniel Keesing

All Theses and Dissertations (ETDs)

X-ray computed tomography: CT) and positron emission tomography: PET) have become widely used imaging modalities for screening, diagnosis, and image-guided treatment planning. Along with the increased clinical use are increased demands for high image quality with reduced ionizing radiation dose to the patient. Despite their significantly high computational cost, statistical iterative reconstruction algorithms are known to reconstruct high-quality images from noisy tomographic datasets. The overall goal of this work is to design statistical reconstruction software for clinical x-ray CT scanners, and for a novel PET system that utilizes high-resolution detectors within the field of view of a whole-body PET scanner. …

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Batf Regulates Previously Unknown Ap-1 Target Genes To Control Th17 Differentiation, Barbara Schraml Jan 2009

Batf Regulates Previously Unknown Ap-1 Target Genes To Control Th17 Differentiation, Barbara Schraml

All Theses and Dissertations (ETDs)

Activator protein 1: AP-1) transcription factors are dimers of Jun, Fos, musculoaponeurotic fibrosarcoma: MAF) and activating transcription factor: ATF) family proteins that are characterized by a basic region and a leucine zipper domain. While many AP-1 proteins also contain defined transcriptional activation domains: TADs), some consist only of a basic region and leucine zipper and are thought to function as inhibitors of AP-1 activity. We found that the AP-1 protein Batf, which lacks a TAD, is highly expressed in T helper cells compared to various other immune cells and tissues. IL-17-producing T helper: TH17) cells are a CD4+ T cell …

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Role Of Ict In Revolutionary Movements Of The Former Soviet Union, And Why There Are No Roses, Oranges, Or Tulips, In Russia, Andrei Skurtu Jan 2009

Role Of Ict In Revolutionary Movements Of The Former Soviet Union, And Why There Are No Roses, Oranges, Or Tulips, In Russia, Andrei Skurtu

All Theses and Dissertations (ETDs)

No abstract provided.

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Numerical Drag Reduction Studies On Generic Truck, Miles Bellman Jan 2009

Numerical Drag Reduction Studies On Generic Truck, Miles Bellman

All Theses and Dissertations (ETDs)

Drag reduction studies on generic truck models using passive shape optimization and active flow control are studied using numerical methods. A genetic algorithm is used to find optimal truck front shapes for reduced drag. The best shape found gives a 3.4% drag reduction. Active flow control is used to reduce drag by using oscillatory synthetic jet actuators on a generic truck body, a D-shaped bluff body, and the Ahmed body. Experimental data is available for these three configurations without and with active flow control. Actuators at the back of the trucks energize separating boundary layers and delay the shedding of …

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Computational Analysis Of Functional Imaging In The Primary Auditory Cortex, Thomas Chen Jan 2009

Computational Analysis Of Functional Imaging In The Primary Auditory Cortex, Thomas Chen

All Theses and Dissertations (ETDs)

Functional imaging can reveal detailed organizational structure in cerebral cortical areas, but neuronal response features and local neural interconnectivity can influence the resulting images, possibly limiting the inferences that can be drawn about neural function. Historically, discerning the fundamental principles of organizational structure in the auditory cortex of multiple species has been somewhat challenging with functional imaging as the studies have failed to reproduce results seen in electrophysiology. One difference might result from the way most functional imaging studies record the summed activity of multiple neurons. To test this effect, virtual mapping experiments were run in order to gauge the …

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Palpable Pedagogy: Expressive Arts, Leadership, And Change In Social Justice Teacher Education (An Ethnographic/Auto-Ethnographic Study Of The Classroom Culture Of An Arts-Based Teacher Education Course), Lucy Elizabeth Barbera Jan 2009

Palpable Pedagogy: Expressive Arts, Leadership, And Change In Social Justice Teacher Education (An Ethnographic/Auto-Ethnographic Study Of The Classroom Culture Of An Arts-Based Teacher Education Course), Lucy Elizabeth Barbera

Antioch University Dissertations & Theses

Palpable Pedagogy: Expressive Arts, Leadership, and Change in Social Justice TeacherEducation is an arts-informed ethnographic study of the pedagogy and culture engendered when the expressive arts are employed in social justice teacher education. Palpable Pedagogy is a qualitative study that examines the power of the expressive arts to identify, explore, and address issues of inequity in the context of a social justice teacher education course that I taught over three consecutive years. The literature in the field outlines the essential components for effective social justice teacher education (identity, reflection, and dialogue) and neatly explores them. However, with the exception of …

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Art, Water, And Circles: In What Ways Do Study Circles Empower Artists To Become Community Leaders Around Water Issues, Jill Beth Jacoby Jan 2009

Art, Water, And Circles: In What Ways Do Study Circles Empower Artists To Become Community Leaders Around Water Issues, Jill Beth Jacoby

Antioch University Dissertations & Theses

This research explored the use of study circles as a means of engaging artists in dialogue with their peers about water related concerns. The question driving this research was, “In what ways do study circles empower artists to become community leaders around water issues?” Secondary questions focused on emerging environmental, water, and social justice themes as well as examples of increased water awareness and behavior change occurring as a result of individual participation in the study circles. Artists have a unique way of commanding attention and communicating about environmental concerns while functioning as catalysts for activism on a variety of …

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Detection Of Numerous Verotoxigenic E. Coli Serotypes, With Multiple Antibiotic Resistance From Cattle Faeces And Soil, L. Scott, P. Mcgee, Ciara Walsh, Seamus Fanning, T. Sweeney, J. Blanco, M. Karczmarczyk, B. Earley, N. Leonard, J.J. Sheridan Jan 2009

Detection Of Numerous Verotoxigenic E. Coli Serotypes, With Multiple Antibiotic Resistance From Cattle Faeces And Soil, L. Scott, P. Mcgee, Ciara Walsh, Seamus Fanning, T. Sweeney, J. Blanco, M. Karczmarczyk, B. Earley, N. Leonard, J.J. Sheridan

Articles

Verotoxigenic E. coli (VTEC) belong to a diverse range of serotypes. Serotypes O157 and O26 are predominately identified in VTEC-associated disease in Europe, however due to difficulty in detection little is known about the epidemiology of non-O157 serotypes. This study reports the identification of 7 VTEC serotypes from cattle faeces and soil. Cattle faeces samples (n = 128) were taken from animals in 6 different farms, with soil samples (n = 20) obtained from 1 farm. After sample incubation in modified tryptone soy broth (mTSB) supplemented with streptomycin sulphate samples were plated onto sorbitol MacConkey (SMAC) also supplemented …

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Childhood Nature Contact And Its Effect On Adult Coping Skills, Mary-Jeanne Raleigh Jan 2009

Childhood Nature Contact And Its Effect On Adult Coping Skills, Mary-Jeanne Raleigh

Antioch University Dissertations & Theses

Reported anxiety levels continue to rise, in conjunction with a decrease in the depth and breath of coping strategies reported in college populations throughout the United States (Arthur, 1998; Twenge, 2000). Emotional management skills begin development in middle childhood (8-12yrs) and transition into adult coping skills in early adulthood (18-24yrs) (Seifert, 2000). The uses of natural restorative environments for coping may be reinforced during developmental phases in which coping skills are being learned. The development of coping strategies incorporating the use of natural restorative environments maybe contingent on early exposure to the qualities of natural restorative space found in routine …

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Seeing Shifts: Ecologists' Lived Experiences Of Climate Change In Mountains Of The American West, Kimberly Ford Langmaid Jan 2009

Seeing Shifts: Ecologists' Lived Experiences Of Climate Change In Mountains Of The American West, Kimberly Ford Langmaid

Antioch University Dissertations & Theses

This study explores the lived experiences of field ecologists who research the effects of global climate change on mountain species and ecosystems in the American West. The purpose is to generate narrative descriptions of ecologists’ experiences in order to communicate about both the scientific ecology and human ecology of climate change. Twenty prominent field ecologists participated in this study. Interviews with ecologists were transcribed and analyzed using a hermeneutic phenomenological methodology. Eight experiential themes emerged through the process of data analysis, and these themes provide the structure for presenting narratives of ecologists’ experiences. The eight themes are: thinking ecologically, the …

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An Examination Of Environmental Collective Identity Development Across Three Life-Stages: The Contribution Of Social Public Experiences At Zoos, John Robert Fraser Jan 2009

An Examination Of Environmental Collective Identity Development Across Three Life-Stages: The Contribution Of Social Public Experiences At Zoos, John Robert Fraser

Antioch University Dissertations & Theses

This research breaks ground toward a revised theory of how collective environmental identity is associated with pro-environmental behaviors. My research comprises three activities that examined the experiences of three groups of people who claim zoo visiting as an important part of their life-story. The three studied groups were; conservation biologists who describe zoo experiences as having significant formative role in their childhood development of environmental values; parents who prioritize zoo visits as an important cultural experiences for their children; and a active zoo volunteers. This research also investigated whether the group experiences these participants had at zoos contributed to the …

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Dispersion Of Large-Seeded Tree Species By Two Forest Primates: Primate Seed Handling, Microhabitat Variability, And Post-Dispersal Seed Fate, Nicole D. Gross-Camp Jan 2009

Dispersion Of Large-Seeded Tree Species By Two Forest Primates: Primate Seed Handling, Microhabitat Variability, And Post-Dispersal Seed Fate, Nicole D. Gross-Camp

Antioch University Dissertations & Theses

I describe the relative effectiveness of two primates in dispersing large-seeded tree seeds (> 0.5 cm) in the Nyungwe National Park (NNP), Rwanda. My objectives are three-fold: (1) to describe the relative effectiveness of primates in dispersing the seeds of five large-seeded tree species, (2) to evaluate the influence of primate seed-handling method on seed fate, and (3) to determine the influence of deposition site on seed fate. I employed focal tree observations, day-follows of habituated primate groups, in situ monitoring of primate-dispersed seeds, and experimental plots to achieve these objectives. Data were collected over the course of one year …

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Flame, Furnace, Fuel: Creating Kansas City In The Nineteenth Century, Twyla Dell Jan 2009

Flame, Furnace, Fuel: Creating Kansas City In The Nineteenth Century, Twyla Dell

Antioch University Dissertations & Theses

Though this work is a fuel and energy history of Kansas City from 1820 to 1920, it also provides a tool to describe and analyze fuel and energy transitions. The four parts follow the rise and fall of wood, coal and oil as their use grows to a peak and, in the case of wood, declines. The founding and growth of Kansas City as an “instant city” that grew from zero population to over three hundred twenty thousand in a hundred years embodies the increased use of fuels and energy in an urban setting and serves as a case study. …

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Historical Review Of Elk-Agriculture Conflicts In And Around Riding Mountain National Park, Manitoba, Canada, Ryan K. Brook Jan 2009

Historical Review Of Elk-Agriculture Conflicts In And Around Riding Mountain National Park, Manitoba, Canada, Ryan K. Brook

Human–Wildlife Interactions

Conflicts between elk (Cervus elaphus) and farmers have been occurring since the 1880s when agriculture began around what is now Riding Mountain National Park (RMNP). Initially, the conflicts were related to low elk numbers caused primarily by unregulated harvest of elk. The creation of RMNP in 1930 and the associated ban on hunting allowed elk numbers to reach critically high levels. Since farming began, elk have been associated with considerable damage to fences and crops around RMNP, with annual damage often >$240,000. Hunting on agricultural lands has been the most common approach to mitigating elk impacts, despite its …

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Factors Contributing To The Success Of A Single-Shot, Multiyear Pzp Immunocontraceptive Vaccine For White-Tailed Deer, Lowell A. Miller, Kathleen A. Fagerstone, Donald C. Wagner, Gary J. Killian Jan 2009

Factors Contributing To The Success Of A Single-Shot, Multiyear Pzp Immunocontraceptive Vaccine For White-Tailed Deer, Lowell A. Miller, Kathleen A. Fagerstone, Donald C. Wagner, Gary J. Killian

Human–Wildlife Interactions

We evaluated 6 different porcine zona pellucida (PZP) preparations used as a single-shot vaccine for multiyear contraception of captive white-tailed deer (Odocoileus virginianus). The study compared 2 PZP preparation technologies from ImmunoVaccine Technologies™ (IVT) and National Wildlife Research Center (NWRC) over a 7-year period. The study compared both the use of oil in an emulsion and in suspension delivery, as well as replacement of the oil with an alum adjuvant. The study demonstrated that the oil emulsion adjuvant provided the longest lasting response. PZP isolated by the IVT provides a longer-lasting response than the preparation used by NWRC. …

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A Tribute To Richard A. Dolbeer Richard A. Dolbeer: Scientist, Innovator, Manager, And Mentor, Bradley F. Blackwell, Travis L. Devault Jan 2009

A Tribute To Richard A. Dolbeer Richard A. Dolbeer: Scientist, Innovator, Manager, And Mentor, Bradley F. Blackwell, Travis L. Devault

Human–Wildlife Interactions

No abstract provided.

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Forensic Bird-Strike Identification Techniques Used In An Accident Investigation At Wiley Post Airport, Oklahoma, 2008, Carla J. Dove, Nor Faridah Dahlan, Marcy Heacker Jan 2009

Forensic Bird-Strike Identification Techniques Used In An Accident Investigation At Wiley Post Airport, Oklahoma, 2008, Carla J. Dove, Nor Faridah Dahlan, Marcy Heacker

Human–Wildlife Interactions

On March 4, 2008, a Cessna Citation 1 (Model 500) crashed in a wooded area near Wiley Post Airport, Oklahoma, killing all 5 people on board. This paper describes the detailed forensic methods and expertise used by the Smithsonian Institution’s Feather Identification Lab to identify the bird that caused this bird-strike incident. We used standard methods of whole-feather analysis, microscopic examination, and DNA barcoding in this case to identify American white pelican (Pelecanus erythrorhynchos) as the bird species involved in this fatal crash. We also report the importance of proper field investigation and evidence collection for accurate results, …

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What Determines Auditory Similarity? The Effect Of Stimulus Group And Methodology., Kirsteen M. Aldrich, Elizabeth J. Hellier, Judy Edworthy Jan 2009

What Determines Auditory Similarity? The Effect Of Stimulus Group And Methodology., Kirsteen M. Aldrich, Elizabeth J. Hellier, Judy Edworthy

School of Psychology

Two experiments on the internal representation of auditory stimuli compared the pairwise and grouping methodologies as means of deriving similarity judgements. A total of 45 undergraduate students participated in each experiment, judging the similarity of short auditory stimuli, using one of the methodologies. The experiments support and extend Bonebright's (1996) findings, using a further 60 stimuli. Results from both methodologies highlight the importance of category information and acoustic features, such as root mean square (RMS) power and pitch, in similarity judgements. Results showed that the grouping task is a viable alternative to the pairwise task with N > 20 sounds whilst …

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Anticipating Intentional Actions: The Effect Of Eye Gaze Direction On The Judgment Of Head Rotation, Matthew Hudson, Chang Hong Liu, Tjeerd Jellema Jan 2009

Anticipating Intentional Actions: The Effect Of Eye Gaze Direction On The Judgment Of Head Rotation, Matthew Hudson, Chang Hong Liu, Tjeerd Jellema

School of Psychology

No abstract provided.

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Tort Duties Of Landowners: A Positive Theory, Keith N. Hylton Jan 2009

Tort Duties Of Landowners: A Positive Theory, Keith N. Hylton

Faculty Scholarship

One of the most controversial areas of modern tort law is that of the duty of landowners toward people who visit their land. The common law divided land visitors into three types: invitees, licensees, and trespassers. The highest duty of care was owed to the invitee and the lowest to the trespasser. The distinctions led courts to hand down harsh decisions and to draw formal lines between the categories that seemed to defy common sense at times. This paper explains the incentive-based function of the classical landowner duties. I will argue that the classical duties served useful regulatory functions. The …

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Event Based Propagation Approach To Constraint Configuration Problems, Rajhdeep Jandir Jan 2009

Event Based Propagation Approach To Constraint Configuration Problems, Rajhdeep Jandir

Master's Theses

No abstract provided.

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Effects Of Prescribed Burning On Composition Of Serpentine Grassland Vegetation, Debra Thornley Welch Jan 2009

Effects Of Prescribed Burning On Composition Of Serpentine Grassland Vegetation, Debra Thornley Welch

Master's Theses

No abstract provided.

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The Effects On Small Mammal Abundance After A Wildfire In The Warner Mountains, Jesse Rose West Jan 2009

The Effects On Small Mammal Abundance After A Wildfire In The Warner Mountains, Jesse Rose West

Master's Theses

No abstract provided.

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Gender, Status And Shellfish In Precontact Hawaii, Robin Helene Connors Jan 2009

Gender, Status And Shellfish In Precontact Hawaii, Robin Helene Connors

Master's Theses

No abstract provided.

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Uses And Gratifications Of The Food Network, Cori Lynn Hemmah Jan 2009

Uses And Gratifications Of The Food Network, Cori Lynn Hemmah

Master's Theses

No abstract provided.

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Conservation And Pasture Value Of Remnant Trees In A Tropical Agroecosystem, Ariel N. Rivers Jan 2009

Conservation And Pasture Value Of Remnant Trees In A Tropical Agroecosystem, Ariel N. Rivers

Master's Theses

No abstract provided.

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The Effects Of Psychosocial Stress And Social Support On Memory, Dong T. H Nguyen Jan 2009

The Effects Of Psychosocial Stress And Social Support On Memory, Dong T. H Nguyen

Master's Theses

No abstract provided.

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Habitat Selection And Activities Of Non-Native Rio Grande Turkeys In An Open Space Preserve, Sara Ornelas Jan 2009

Habitat Selection And Activities Of Non-Native Rio Grande Turkeys In An Open Space Preserve, Sara Ornelas

Master's Theses

No abstract provided.

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The Box Office Effects Of Casting Celebrities As Replacement Actors On Broadway, Douglas Santana Jan 2009

The Box Office Effects Of Casting Celebrities As Replacement Actors On Broadway, Douglas Santana

Master's Theses

No abstract provided.

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