Digital Commons Network^™

Empirical Processes And Roc Curves With An Application To Linear Combinations Of Diagnostic Tests, Costel Chirila

University of Kentucky Doctoral Dissertations

The Receiver Operating Characteristic (ROC) curve is the plot of Sensitivity vs. 1- Specificity of a quantitative diagnostic test, for a wide range of cut-off points c. The empirical ROC curve is probably the most used nonparametric estimator of the ROC curve. The asymptotic properties of this estimator were first developed by Hsieh and Turnbull (1996) based on strong approximations for quantile processes. Jensen et al. (2000) provided a general method to obtain regional confidence bands for the empirical ROC curve, based on its asymptotic distribution.

Since most biomarkers do not have high enough sensitivity and specificity to …

Effect Of The SmartstepTm Stabilization System On Balance In Older Adults In An Independent Living Residence, Ann L. Livengood

University of Kentucky Doctoral Dissertations

An increase in postural sway is one of the risk factors that have been linked to an increased incidence of falls in the older adult population. Researchers have shown that peripheral sensation is crucial in maintaining a static posture for adults of all ages. It has been reported that older adults have decreased tactile sensation of the plantar surface of their feet. and when the sensory feedback was increased older adults had improved postural control. It was hypothesized that facilitation of the sole of the foot with the use of a semirigid foot orthotic would result in improved postural stability …

Matrix Decomposition For Data Disclosure Control And Data Mining Applications, Jie Wang

University of Kentucky Doctoral Dissertations

Access to huge amounts of various data with private information brings out a dual demand for preservation of data privacy and correctness of knowledge discovery, which are two apparently contradictory tasks. Low-rank approximations generated by matrix decompositions are a fundamental element in this dissertation for the privacy preserving data mining (PPDM) applications. Two categories of PPDM are studied: data value hiding (DVH) and data pattern hiding (DPH). A matrix-decomposition-based framework is designed to incorporate matrix decomposition techniques into data preprocessing to distort original data sets. With respect to the challenge in the DVH, how to protect sensitive/confidential attribute values without …

A Precision Instrument For Research Into Nanolithographic Techniques Using Field-Emitted Electron Beams, King-Fu Hii

University of Kentucky Doctoral Dissertations

Nanomanufacturing is an active research area in academia and industry due to the ever-growing demands for precision surface modifications of thin films or substrates with nanoscale features. Conventional lithographic techniques face many challenges as they approach their fundamental limits. Consequently, new nanomanufacturing tools, fabrication techniques, and precision instruments are being explored and developed to meet these challenges. It has been hypothesized that direct-write nanolithography might be achieved by using a field-emitted electron beam for nanomachining. This dissertation moves this research one step closer by developing a precision instrument that can enable the integration of direct-write nanolithography by a field-emitted electron …

The Role Of Spiders In The Detrital Food Web Of An Eastern Deciduous Forest, Erin Elizabeth Hladilek

University of Kentucky Doctoral Dissertations

Historically, terrestrial food web research has focused on describing the structure of aboveground grazing webs, and determining how interactions among plants, herbivores and higher trophic levels influence primary productivity. Detrital food webs however, play a significant role in regulation of ecosystem dynamics through direct impacts on decomposition. Unraveling the complex nature of detrital food web structure is critical to developing a better understanding of ecosystem function. Therefore the primary objective of this research was to describe the structure of the leaf-litter food web in a temperate deciduous forest, with emphasis on interactions between a community of generalist predators, the forest-floor …

A Novel Class Of Immunoproteasome Catalytic Subunit Lmp2 Inhibitor And Its Therapeutic Potentials In Cancer, Yik Khuan (Abby) Ho

University of Kentucky Doctoral Dissertations

The immunoproteasome, known to play an important role in MHC class I antigen processing and presentation, have been linked to neurodegenerative diseases and hematological cancers. However, the pathophysiological functions of the immunoproteasome in these diseases are still not very well established. This can be attributed mainly to the lack of appropriate molecular probes that selectively target the immunoproteasome catalytic subunits. Herein, we report the development of a small molecular inhibitor (AM) that selectively targets the major catalytic subunit, LMP2, of the immunoproteasome. We show that the compound covalently modifies the LMP2 subunit with high specificity in human prostate …

Linking The Structure And Mechanical Behavior Of Nanoporous Gold, Ye Sun

University of Kentucky Doctoral Dissertations

The structure of nanoporous gold (np-Au) provides a very limited volume for deformation to occur, and thus offers an opportunity to study the role of defects such as dislocations in nanoscale metal volumes. A practical goal is to understand mechanical properties of np-Au so that it can be can produced in stable form, for use in applications that require some mechanical integrity. Bulk and thin film np-Au have been fabricated and studied here.

Bulk np-Au was prepared by electrochemically dealloying Au-Ag alloys with 25 and 30 at.% Au. In the lower Au content material, cracks always formed during dealloying. When …

The Interaction Of Haptic Imagery With Haptic Perception For Sighted And Visually Impaired Consumers, Shannon Bridgmon Rinaldo

University of Kentucky Doctoral Dissertations

Consumers evaluate products in the market place using their senses and often form mental representations of product properties. These mental representations have been studied extensively. Imagery has been shown to interact with perception within many perceptual modalities including vision, auditory, olfactory, and motor. This dissertation draws on the vast visual imagery literature to examine imagery in the haptic, or touch, modality. Two studies were undertaken to examine the relationship between haptic imagery and haptic perception The first study is based on studies from cognitive psychology that have used similar methods for examining visual imagery and visual perception. In study 1, …

Consumer Protection In The Americas: A Second Wave Of American Revolutions?, Antonio F. Perez

Scholarly Articles

This article, which draws on the author's experience as a member of the Inter-American Juridical Committee of the Organization of American States, focuses on the problem of crafting an appropriate hemispheric regime for the protection of consumer rights. The subject is now a major element in the agenda of the OAS Specialized Conference on Private International Law (know also under its Spanish acronym as the CIDIP process), in part because of the increased salience of the issue in light of increasing e-commerce. The article, based on the author's presentation at a symposium at the St. Thomas School of Law in …

Back From Wonderland: A Linguistic Approach To Duties Arising From Threats Of Physical Violence, A.G. Harmon

Scholarly Articles

No abstract provided.

A Gift Worth Dying For?: Debating The Volitional Nature Of Suicide In Personal Property Law, Adam J. Macleod

Scholarly Articles

This article examines the debate in personal property law over the question whether suicide is ever a volitional act and the attendant issue whether a gift causa mortis ought to be enforced when made conditional upon an act of suicide. Scholars have missed substantial doctrinal changes in the law of gifts causa mortis during the last thirty-three years. These changes bear upon other contested, legal issues, such as the wisdom of legalizing assisted suicide.The article tests the modern rule that all gifts made in contemplation of suicide are enforceable and the assumption on which this rule is predicated, namely that …

Milk Teeth And Jet Planes: Kin Relations In Families Of Sri Lanka’S Transnational Domestic Servants, Michele Ruth Gamburd

Anthropology Faculty Publications and Presentations

This essay examines the confluence of local and global dynamics, exploring how transnational migration affects and is affected by gender roles, kinship relations, intergenerational obligations, and ideologies of parenthood. Journeying to the Middle East repeated on two-year labor contracts, many of Sri Lanka’s migrant housemaids leave behind their husbands and children. Women’s long-term absences reorganize and disrupt widely accepted gendered attributions of parenting roles, with fathers and female relatives taking over household tasks. Migrants say that economic difficulties prompt migration, and assess commitment to kin in financial terms. The government also benefits from remittances. Nevertheless, stakeholders (villagers, politicians, and the …

Large Domestic Pits On The Northwest Coast Of North America, Kenneth M. Ames, Cameron M. Smith, Alexander Bourdeau

Anthropology Faculty Publications and Presentations

Excavations of prehistoric and contact-period houses on the southern Northwest Coast of North America have exposed very large interior pit complexes. The complexes are either long trenches or rows of pits beneath the house floors. They are associated with substantial permanently occupied houses dated to between 300 CAL B.G. and A.D. 1830. The pits add significantly to the storage potentials of these houses and suggest surplus production.

On The Use Of Emg-Ratios To Assess The Coordination Of Back Muscles, Christian Larivière, A. Bertrand Arsenault

Études primaires

No abstract provided.

The Assessment Of Back Muscle Capacity Using Intermittent Static Contractions. Part I: Validity And Reliability Of Electromyographic Indices Of Fatigue, Christian Larivière, Denis Gagnon, Denis Gravel, A. Bertrand Arsenault

Études primaires

No abstract provided.

Paleogene Mirelands Of The Upper Mississippi Embayment, Western Kentucky, Jennifer Marie Klein O'Keefe

University of Kentucky Doctoral Dissertations

Detailed petrography, geochemistry, and palynology together describe the depositional environments and paleoecology of an abandoned meander-fill system in western Kentucky. Oriented block petrography reveals alternating clay-rich and attrinite-rich zones of variable thickness. Woody tissues, where present, do not show dessication features and deflation layers could not be identified. Overall, petrography is indicative of a topogenous mire. Mire palyno-assemblages are less diverse than assemblages reported from clays in the region. Castanea-Cupuliferoidaepollenites assemblages dominate the entire system and other tree pollen are common; fungal spores are relatively uncommon. Weighted statistical analyses reveal ecological groupings beyond this dominance and define botanical succession within …

20081104.9: Buildings And Grounds, 1973-2006, Buildings And Grounds

Guides to University Archives

These items include materials from what is now known as Physical Plant and Facilities at Marshall University from 1973-2006. Items were received in 2008 and include notable materials about the Robert C. Byrd Biotechnology Science Center construction, Men's health and physical education building, Marshall University's "White House", and MU Acquisitions Program. This is not an exhaustive list, but the attached inventory will give a broad overview of what is contained in each of the boxes.

2008114.11: Buildings And Grounds, 1916-2004, Buildings And Grounds

Guides to University Archives

These items include materials from what is now known as Physical Plant and Facilities at Marshall University from 1966-2003. Items were received in 2008 and include notable materials about the John R. Hall Center for Academic Excellence, Program Dedication of Northcott Science Hall, Fairfield Stadium Dedication, and the John Marshall Statue dedication and John Deaver Drinko Library schedule. This is not an exhaustive list, but the attached inventory will give a broad overview of what is contained in each of the boxes.

2008114.10: Buildings And Grounds, 1966-2003, Buildings And Grounds

Guides to University Archives

These items include materials from what is now known as Physical Plant and Facilities at Marshall University from 1966-2003. Items were received in 2008 and include notable materials about Harless Dining Hall, Biotech Science Center Pedestrian Bridge, MU Building for the future, and Marshall University Campus Design 21st Century. This is not an exhaustive list, but the attached inventory will give a broad overview of what is contained in each of the boxes.

Avoidance Of Hydrolyzed Casein By Mice, Kristin L. Field, Bruce A. Kimball, Julie A. Mennella, Gary K. Beauchamp, Alexander A. Bachmanov

United States Department of Agriculture Wildlife Services: Staff Publications

When casein, a milk protein, is hydrolyzed, it renders human foods that contain it (e.g., hypoallergenic infant formula, cheeses) distasteful to many people. This rejection of hydrolyzed casein (HC)-containing foods has recently been found to also occur in a non-human species (deer, Odocoileus spp.). Identifying other animals that avoid HC would facilitate understanding how and why HC-containing food is often rejected. This study determined whether HC-containing food is avoided by Mus musculus and whether consumption patterns were sensitive to testing conditions, specifically food form (powder, pellet or dough) and food access (ad libitum or 1.5 h/day following 6 h …

Evaluation Of Stop-Level Vs. Route-Level Breeding Bird Survey Counts For Modeling The Influence Of Land Use And Climate On Breeding Blackbird Abundance In North Dakota, Michelle L. Petersen, George M. Linz, Greg Forcey, Wayne Thogmartin, William J. Bleier

United States Department of Agriculture Wildlife Services: Staff Publications

The Red-winged Blackbird (Agelaius phoeniceus), Yellow-headed Blackbird (Xanthocephalus xanthocephalus), and Common Grackle (Quiscalus quiscula) are the three most abundant blackbird species (Icteridae) found in North Dakota and comprise almost 10% of its avian population (Stewart and Kantrud 1972). Blackbird abundance combined with their food habitats make them significant agricultural pests on sunflower. Cost estimates for blackbird damage to sunflower in the North Dakota are likely over $10 million dollars annually (Kleingartner, pers. comm). Because of this economic impact blackbirds have on agriculture, it is important to understand land use and climatic factors influencing blackbird …

Development Of Polymorphic Microsatellite Loci For The Common Vampire Bat, Desmodus Rotundus (Chiroptera: Phylostomidae), Antoinette J. Piaggio, John J. Johnston, Susan L. Perkins

United States Department of Agriculture Wildlife Services: Staff Publications

The common vampire bat (Desmodus rotundus) is one of three haematophagous species of bats and the only species in this genus. These New World bats prey on mammals and create significant economic impacts through transmission of rabies in areas where livestock are prevalent. Furthermore, in some portions of their range, it is not uncommon for them to prey upon humans. It is critical to the management of this species and for understanding the spread of bat rabies that detailed studies of D. rotundus population structure be conducted. To further such studies, we have characterized 12 microsatellite loci for …

Isolation Of Microsatellite Loci From The Coqui Frog, Eleutherodactylus Coqui, Maureen B. Peters, Karen H. Beard, Cris Hagen, Eric M. O'Neill, Karen E. Mock, William Pitt

United States Department of Agriculture Wildlife Services: Staff Publications

Thirteen microsatellite loci were isolated from the coqui frog (Eleutherodactylus coqui) and optimized for future research. The loci were screened across 37 individuals from two Puerto Rican populations. Loci were variable with the number of alleles per locus ranging from three to 38. Polymorphic information content ranged from 0.453 to 0.963 and observed heterozygosity for each population ranged from 0.320 to 0.920.

Evaluation Of An Electrified Mat As A White-Tailed Deer (Odocoileus Virginianus) Barrier, Thomas W. Seamans, David A. Helon

United States Department of Agriculture Wildlife Services: Staff Publications

White-tailed deer (Odocoileus virginianus) pose economic and safety problems for agricultural and transportation industries. We tested an electronic mat to determine if it would reduce deer crossing through fence openings. We measured deer intrusions and corn consumption at five sites with charged mats and five sites with non-charged mats. Weekly intrusions at treated sites decreased an average of 95% from pre-treatment. Weekly intrusions at control sites were reduced 60% during weeks 1 and 2 and increased to 10% reduction by week 6. Weekly corn consumption at treated sites decreased from pretreatment through all treatment weeks. Weekly corn consumption …

Estimating The Efficacy Of Drc-1339-Treated Rice Bait In Blackbird Staging Areas In North Dakota Using A Bioenergetics Simulation, Randal S. Stahl, John J. Johnston, George M. Linz

United States Department of Agriculture Wildlife Services: Staff Publications

DRC-1339 is a pesticide used to induce mortality in pest birds and is being used successfully to reduce bird damage to a variety of agricultural products. The feasibility of using live decoy traps baited with DRC-1339-treated rice baits is being evaluated for reducing blackbird damage to sunflower in North Dakota. To estimate the take associated with the use of the DRC-1339-treated rice baits, we developed a bioenergetics simulation to estimate bait consumption by red-winged blackbirds, yellow-headed blackbirds and common grackles. This simulation incorporates a module to estimate mortality based on the amount of treated bait eaten by individual birds and …

Managing Deer Damage In Nebraska, Scott E. Hygnstrom, Stephen M. Vantassel, Bruce D. Trindle, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Deer browse a variety of plants, especially when densities are high or forage is limited. This browsing can damage trees, plants, vines, and fruit. This guide discusses how to recognize, manage, and minimize deer damage.

The Single-Shot Gnrh Immunocontraceptive Vaccine (GonaconTm ) In White-Tailed Deer: Comparison Of Several Gnrh Preparations, Lowell A. Miller, James P. Gionfriddo, Kathleen A. Fagerstone, Jack C. Rhyan, Gary J. Killian

United States Department of Agriculture Wildlife Services: Staff Publications

Problem: An effective, single-injection, multi-year, GnRH contraceptive agent is needed to control reproduction in overabundant white-tailed deer populations.

Method of study: Two GnRH conjugates, GonaCon^TM (GnRH–KLH) and GonaCon-B^TM (GnRH–blue protein), were prepared in emulsion form as one-injection and two-injection immunocontraceptive vaccine formulations. In addition, the GnRH–KLH protein conjugate was lyophilized and suspended in AdjuVac^TM adjuvant to produce a fifth vaccine formulation. Each formulation was administered to a group of five captive adult female white-tailed deer. Reproductive performance of treated female deer was monitored for 5 years to determine the comparative efficacy of the various treatments.

Results: The …

Deer Impact On Vegetation In Natural Areas In Southeastern Nebraska, Joseph Gubanyi, Julie A. Savidge, Scott E. Hygnstrom, Kurt C. Vercauteren, Gary W. Garabrandt, Seth Korte

United States Department of Agriculture Wildlife Services: Staff Publications

We studied the effect of browsing by white-tailed deer (Odocoileus virginianus Zimmerman) on vegetation at three sites with high densities of deer and six sites with low densities of deer along the Missouri and Platte Rivers in southeastern Nebraska in 1995-1996. Vegetation volume from 0-1 m high was similar between sites with high and low deer densities (P > 0.05). From 1-2 m high, vegetation volume was less at sites with more deer in both years (P < 0.05). Densities for eight of 11 small woody plant categories (< 3 cm dbh) were less common at sites with high densities of deer (P < 0.05). Overall densities of small trees (3-15 cm dbh) were similar between sites with high and low densities of deer. However, small hackberry trees (Celtis occidentalis L.) were more common (P = 0.03), while all other small trees were less common (P = 0.038), at sites with …

An Integrated Vehicle-Mounted Telemetry System For Vhf Telemetry Applications, Jason Gilsdorf, Kurt C. Vercauteren, Scott E. Hygnstrom, W. David Walter, Justin Boner, Greg Clements

United States Department of Agriculture Wildlife Services: Staff Publications

We designed and developed a vehicle-mounted very high frequency–based telemetry system that integrated an on-board antenna, receiver, electronic compass, Global Positioning System, computer, and Geographic Information System. The system allows users to accurately and quickly obtain fixes, estimate and confirm locations of radio-marked animals, and immediately record data into an electronic spreadsheet or database. The total cost of materials to build the system was $7,349 (United States currency). Mean error angle of 2.63 ± 12.1° (SD; range =-33.7–42.2°) and mean location error distance of 128 ± 91.3 m (SD; range = 0–408 m) suggested precision and accuracy of our system …

Livestock Protection Dogs For Deterring Deer From Cattle And Feed, Kurt C. Vercauteren, Michael J. Lavelle, Gregory Phillips

United States Department of Agriculture Wildlife Services: Staff Publications

Disease transmission between wildlife and livestock is a worldwide issue. Society needs better methods to prevent interspecies transmission to reduce disease risks. Producers have successfully used livestock protection dogs (LPDs) for thousands of years to reduce predation. We theorized that LPDs raised and bonded with cattle could be used to also reduce risk of bovine tuberculosis (Myobacterium bovis; TB) transmission between white-tailed deer (Odocoileus virginianus) and cattle by minimizing contact between the 2 species and use of cattle feed by deer. We evaluated 4 LPDs over 5 months, utilizing 2 data collection methods (direct observation and …