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2008

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Articles 2431 - 2460 of 15507

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Wrl Newsletter October 2008, Maryke Barber Oct 2008

Wrl Newsletter October 2008, Maryke Barber

WRL Newsletters

No abstract provided.


A Study Of Early Stage Game Design And Prototyping, Brien Colwell, Richard C. Davis, James A. Landay Oct 2008

A Study Of Early Stage Game Design And Prototyping, Brien Colwell, Richard C. Davis, James A. Landay

Research Collection School Of Computing and Information Systems

Computer games and simulations can be valuable teaching and communication tools, and they are a powerful form of self-expression. Unfortunately, creating games requires programming, and programming requires time and skill. Some tools facilitate game creation to motivate novice programmers, but programming is still necessary. Other systems require less programming, but they are narrowly focused. To enable faster, simpler, and more expressive tools for professionals and amateurs, we have explored the processes and tools used in the early stages of game and simulation design. Interviews with educators clarified the uses of simulations in the classroom, while interviews with professional game designers …


Undue Influence And The Law Of Wills: A Comparative Analysis, Ronald J. Scalise Jr. Oct 2008

Undue Influence And The Law Of Wills: A Comparative Analysis, Ronald J. Scalise Jr.

Duke Journal of Comparative & International Law

No abstract provided.


Is It Safe To Drink The Water?, James Salzman Oct 2008

Is It Safe To Drink The Water?, James Salzman

Duke Environmental Law & Policy Forum

No abstract provided.


The Dirt On International Environmental Law Regarding Soils: Is The Existing Regime Adequate?, Alexandra M. Wyatt Oct 2008

The Dirt On International Environmental Law Regarding Soils: Is The Existing Regime Adequate?, Alexandra M. Wyatt

Duke Environmental Law & Policy Forum

No abstract provided.


Si Cycle In The Cariaco Basin, Venezuela: Seasonal Variability In Silicate Availability And The Si:C:N Composition Of Sinking Particles, Robert Thunell, Claudia R. Benitez-Nelson, Frank Muller-Karger, Laura Lorenzoni, Kent Fanning, Mary Scranton, Ramon Varela, Yrene Astor Oct 2008

Si Cycle In The Cariaco Basin, Venezuela: Seasonal Variability In Silicate Availability And The Si:C:N Composition Of Sinking Particles, Robert Thunell, Claudia R. Benitez-Nelson, Frank Muller-Karger, Laura Lorenzoni, Kent Fanning, Mary Scranton, Ramon Varela, Yrene Astor

Faculty Publications

[1] A 9‐year time series of water column and sediment trap measurements was used to examine silicon cycling within the anoxic Cariaco Basin. The dynamic hydrographic regime within Cariaco Basin results in strong seasonal changes in nutrient availability and the Si:C:N of sinking particles. Upwelling in early winter injects silicic acid (Si(OH)4= ) and nitrate (NO3−) rich waters into the photic zone which stimulates primary production and results in opal fluxes in excess of 4 mmol Si m−2 d−1. However, even during upwelling, surface waters tend to be depleted (μM) in both Si(OH)4= and NO3− as a result …


At The Watershed: Preparing For Research Data Management And Stewardship At The University Of Minnesota Libraries, Leslie M. Delserone Oct 2008

At The Watershed: Preparing For Research Data Management And Stewardship At The University Of Minnesota Libraries, Leslie M. Delserone

University of Nebraska-Lincoln Libraries: Faculty Publications

Like many research universities, the University of Minnesota (UMN), and its Libraries, attempts to understand the nature and intensity of data produced by its researchers, and address the management and stewardship of its institutional research output. The recent activities of the Libraries, in support of and in conjunction with campus-wide efforts, illustrate a set of approaches that show the Libraries to be at the watershed, integrated into and contributing leadership to the growing river of campus-wide exploration and planning of cyberinfrastructure needs. This brief article highlights the hiring of the “science librarian cohort,” the Libraries’ study concerning the needs and …


Ultraviolet And Pulsed Electric Field Treatments Have Additive Effect On Inactivation Of E. Coli In Apple Juice, T. K. Gachovska, Saurabh Kumar, Harshanardhan Thippareddi, F. Williams Oct 2008

Ultraviolet And Pulsed Electric Field Treatments Have Additive Effect On Inactivation Of E. Coli In Apple Juice, T. K. Gachovska, Saurabh Kumar, Harshanardhan Thippareddi, F. Williams

P. F. (Paul Frazer) Williams Publications

Apple juice inoculated with Escherichia coli ATCC 23472 was processed continuously using either ultraviolet (UV), high-voltage pulsed electric field (PEF), or a combination of the PEF and UV treatment systems. Apple juice was pumped through either of the systems at 3 flow rates (8, 14, and 20 mL/min). E. coli was reduced by 3.46 log CFU/mL when exposed in a 50 cm length of UV treatment chamber at 8 mL/min (2.94 s treatment time with a product temperature increase of 13 °C). E. coli inactivation of 4.87 log CFU/mL was achieved with a peak electric field strength of 60 kV/cm …


Effects Of Psychotropic Drugs On The Thrombin-Induced Liberation Of Arachidonate In Human Platelets, Ramadhan Oruch, Ian F. Pryme, Holm Holmsen Oct 2008

Effects Of Psychotropic Drugs On The Thrombin-Induced Liberation Of Arachidonate In Human Platelets, Ramadhan Oruch, Ian F. Pryme, Holm Holmsen

Saudi Medical Journal

OBJECTIVE: To compare the effects of chlorpromazine (CPZ), prochlorperazine (PCP), trifluoperazine (TFP), clozapine (CLO), haloperidol (HPD), quetiapine (QTP), pimozide (PMZ), and olanzapine (OLP) as well as the tricyclic antidepressants amitriptyline AMI, imipramine IMI, and nortriptyline NTP on thrombin-induced liberation of arachidonic acid AA in platelets. METHODS: This work was carried out at the Department of Biomedicine, University of Bergen, Norway in 2006-2007. Human platelets pre labelled with [3H] arachidonate were incubated with thrombin in the absence and presence of the drugs, and the amount of free [3H] arachidonate liberated was determined. Myosin light chain (MLC) phosphorylation was determined in [32P] …


Are Endoscopic Grading And Scoring Systems In Inflammatory Bowel Disease The Same?, Shen Jun, Ran Z. Hua, Tong J. Lu, Chen Xiang, Xiao S. Dong Oct 2008

Are Endoscopic Grading And Scoring Systems In Inflammatory Bowel Disease The Same?, Shen Jun, Ran Z. Hua, Tong J. Lu, Chen Xiang, Xiao S. Dong

Saudi Medical Journal

OBJECTIVE: To assess the correlation and difference between various endoscopic grades and indices for assessment of endoscopic disease activity in inflammatory bowel disease (IBD). METHODS: Eighty consecutive patients with ulcerative colitis (UC), and 31 patients with Crohn9s disease (CD) were evaluated based on multiple endoscopic criteria between June 2006 and February 2007 at the Department of Gastroenterology of Renji Hospital, Shanghai, China. Two experienced endoscopists evaluated the endoscopic findings using various systems independently. Data were analyzed using Kendall9s coefficient of concordance and Spearman correlations. RESULTS: For the systems of UC and CD, Kendall9s coefficients of concordance were 0.714 (p<0.001) and 0.342 (p<0.001). There was no significant difference between the 2 systems of UC (all p<0.01). However, no statistically significant concordances were found between Chinese Grading System of Crohn9s Disease (CGSCD) and Crohn9s Disease Endoscopic Index of Severity (CDEIS) (rs=0.323, p=0.076). Significant differences in frequencies were detected among endoscopic systems for UC (p=0.001). CONCLUSION: It was suggested in our study that endoscopic grading and scoring systems of UC had satisfactory concordance, and CGSCD showed room for improvement. However, the modified Baron scale was tend to severe category, while Jeroen classification was tend to mild category.


Stem Cell Transplantation In Hematological Disorders. A Developing Country Experience-Impact Of Cost Considerations, Maha M. El-Zimaity, Essam A. Hassan, Nazek A. Mahmoud, Amal M. Elafifi, Mohamed M. Moussa, Ghada M. El-Gohary, Mona M. Hagras, Nadia M. Mowafy Oct 2008

Stem Cell Transplantation In Hematological Disorders. A Developing Country Experience-Impact Of Cost Considerations, Maha M. El-Zimaity, Essam A. Hassan, Nazek A. Mahmoud, Amal M. Elafifi, Mohamed M. Moussa, Ghada M. El-Gohary, Mona M. Hagras, Nadia M. Mowafy

Saudi Medical Journal

OBJECTIVE: To describe the experience in setting up a bone marrow transplant program at Ain Shams University, Cairo, Egypt. METHODS: Sixteen patients were transplanted at Ain Shams University Bone Marrow Transplantation unit from March 2005 to January 2008. RESULTS: Sixteen patients were transplanted with a median age of 25 years. Indications for transplantation were chronic myeloid leukemia, acute myeloid leukemia, aplastic anemia, acute lymphoblastic leukemia, and aggressive lymphoma. Seven donors and 6 patients were positive for cytomegalovirus immunoglobulin G (IgG) antibody (Ab) pretransplant. Only one patient was positive for toxoplasma IgG Ab and another had a high titre for toxoplasma …


Historic And Recent Distributions Of Elk In Nebraska, Kent A. Fricke, Michael A. Cover, Scott E. Hygnstrom, Hugh H. Genoways, Scott R. Groepper, Kit Hams, Kurt C. Vercauteren Oct 2008

Historic And Recent Distributions Of Elk In Nebraska, Kent A. Fricke, Michael A. Cover, Scott E. Hygnstrom, Hugh H. Genoways, Scott R. Groepper, Kit Hams, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Elk (Cervus elaphus) were historically found throughout North America but were extirpated from Nebraska and much of the Great Plains in the 1880s due to consumptive uses by settlers, miners, market hunters, and others. Elk began to reappear in Nebraska in the 1950s and 1960s, and established a stable, nonmigratory population that currently consists of seven herds and an estimated 1,400 individuals throughout western and central Nebraska. The reappearance and subsequent persistence of elk in Nebraska suggests there is adequate habitat to support a self-sustaining population. The general movement of elk eastward may lead to an eventual statewide …


A New Species Of Lentiella (Cestoda: Anoplocephalidae) From Proechimys Simonsi (Rodentia: Echimyidae) In Bolivia = Una Especie Nueva De Lentiella (Cestoda: Anoplocephalidae) De Proechimys Simonsi (Rodentia: Echimyidae) En Bolivia, Terry R. Haverkost, Scott Lyell Gardner Oct 2008

A New Species Of Lentiella (Cestoda: Anoplocephalidae) From Proechimys Simonsi (Rodentia: Echimyidae) In Bolivia = Una Especie Nueva De Lentiella (Cestoda: Anoplocephalidae) De Proechimys Simonsi (Rodentia: Echimyidae) En Bolivia, Terry R. Haverkost, Scott Lyell Gardner

Harold W. Manter Laboratory of Parasitology: Faculty Publications

During a biodiversity survey of mammals and their parasites in the Beni, Bolivia in the summer of 2000, several spiny rats, Proechimys simonsi Thomas, 1900, were collected and examined for parasites. Herein we describe Lentiella lamothei n. sp. from one of these hosts. This species is can be distinguished from L. machadoi Rêgo, 1964 by having a greater total length but smaller maximum width, a greater number of segments, a smaller cirrus sac, a smaller scolex diameter, and in the eggs, a larger pyriform apparatus. In addition, we formally validate the genus Lentiella Rêgo, 1964, that had been placed in …


Endoparasites Of Fat-Tailed Mouse Opossums (Thylamys: Didelphidae) From Northwestern Argentina And Southern Bolivia, With The Description Of A New Species Of Tapeworm, F. Agustin Jimenez Ruiz, Janet K. Braun, Mariel Campbell, Scott Lyell Gardner Oct 2008

Endoparasites Of Fat-Tailed Mouse Opossums (Thylamys: Didelphidae) From Northwestern Argentina And Southern Bolivia, With The Description Of A New Species Of Tapeworm, F. Agustin Jimenez Ruiz, Janet K. Braun, Mariel Campbell, Scott Lyell Gardner

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The parasite fauna of two species of fat-tailed mouse opossums from northwestern Argentina is herein presented. Five species of helminths were found, i.e., Pterygodermatites kozeki, Hoineffia simplispicula, Oligacanthorhynchus sp., and a new species of tapeworm, Mathevotaenia sanmartini n. sp. (Cyclophyllidea: Anoplocephalidae). The new species is characterized by a calyciform scolex, relatively few testes (32), and a long cirrus sac; it occurs in fat-tailed mouse opossums at localities above 4,000 m. Those characters make it different from 6 species known to occur in marsupials from the New World, and from other species occurring in armadillos and bats. Didelphoxyuris thylamisis …


Does Place Explain Racial Health Disparities? Quantifying The Contribution Of Residential Context To The Black/White Health Gap In The United States, Brian K. Finch, D. Phuong Do, Ricardo Basurto-Davila, Chloe E. Bird, José J. Escarce, Nicole Lurie Oct 2008

Does Place Explain Racial Health Disparities? Quantifying The Contribution Of Residential Context To The Black/White Health Gap In The United States, Brian K. Finch, D. Phuong Do, Ricardo Basurto-Davila, Chloe E. Bird, José J. Escarce, Nicole Lurie

Faculty Publications

The persistence of the black health disadvantage has been a puzzling component of health in the United States in spite of general declines in rates of morbidity and mortality over the past century. Studies that have focused on well-established individual-level determinants of health such as socio-economic status and health behaviors have been unable to fully explain these disparities. Recent research has begun to focus on other factors such as racism, discrimination, and segregation. Variation in neighborhood context - socio-demographic composition, social aspects, and built environment - has been postulated as an additional explanation for racial disparities, but few attempts have …


Breast Cancer Survival Among Economically Disadvantaged Women: The Influences Of Delayed Diagnosis And Treatment On Mortality, Emily Rose Smith, Swann Arp Adams, Irene Prabhu Das, Matteo Bottai, Jeanette Fulton, James R. Hébert Oct 2008

Breast Cancer Survival Among Economically Disadvantaged Women: The Influences Of Delayed Diagnosis And Treatment On Mortality, Emily Rose Smith, Swann Arp Adams, Irene Prabhu Das, Matteo Bottai, Jeanette Fulton, James R. Hébert

Faculty Publications

Breast cancer affects thousands each year in the United States, and disproportionately affects certain subgroups. For example, the incidence of breast cancer in South Carolina is lower in African American compared with European American women by ~12% to 15%, but their mortality rate is twice as high as in European American women. The purpose of the study was to assess factors associated with breast cancer mortality between African American and European American women. Participants (n = 314) in South Carolina's Breast and Cervical Cancer Early Detection Program (SCBCCEDP), which provides breast cancer screening and treatment services, during the years …


Convergence Of Agriculture And Energy: Iii. Considerations In Biodiesel Production, Jon Van Gerpen, Allan Gray, Brent H. Shanks, Beth Calabotta, Drew Kershen, Alan Weber, Richard Joost, Todd A. Peterson Oct 2008

Convergence Of Agriculture And Energy: Iii. Considerations In Biodiesel Production, Jon Van Gerpen, Allan Gray, Brent H. Shanks, Beth Calabotta, Drew Kershen, Alan Weber, Richard Joost, Todd A. Peterson

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Concern about rising prices and unstable sources of petroleum fuels is driving the search for U.S. domestically produced, renewable transportation fuels, such as biodiesel. Federal incentives of up to $1.10 per gallon have been supplemented by additional incentives and mandated biodiesel use in many states. The Renewable Fuel Standard in the Energy Independence and Security Act of 2007 requires the domestic use of 1 billion gallons of biomass-based diesel fuel by 2012, most of which likely will be biodiesel.
U.S. biodiesel production is primarily from soybean oil, but recent high prices have forced many producers to use lower-cost feedstocks such …


Patient-Tailored Medicine, Part One: The Impact Of Race And Genetics On Medicine, Corrine Parver Oct 2008

Patient-Tailored Medicine, Part One: The Impact Of Race And Genetics On Medicine, Corrine Parver

Scholarly Articles in Law Reviews & Journals

One of the more controversial elements of advancing technology is the use of race and genetics to help create more specific types of medicines that will help combat diseases and conditions that appear to be more prevalent within certain races or ethnic groups than in others. Considering the history of discrimination and inadequate treatment of individuals on the bases of race and gender in the United States, there is justifiable concern that race or gender-based treatment could be used to legitimate discrimination. On the other hand, there is substantial proof that the current method of creating medicines for the general …


New Book Chapter Reviewing Mojave Desert Revegetation Practices Is Forthcoming, Scott R. Abella Oct 2008

New Book Chapter Reviewing Mojave Desert Revegetation Practices Is Forthcoming, Scott R. Abella

Public Policy and Leadership Faculty Research

I was invited to write a chapter for a forthcoming book on Arid Environments to be published by Nova Science Publishers. This book is anticipated to appear in late 2008 or early 2009, and we will be able to provide additional details about the entire book at that time. I co-authored our chapter on revegetation with Alice Newton, Vegetation Manager at Lake Mead National Recreation Area. We systematically reviewed 23 published studies of planting or seeding native species in the Mojave Desert.


A Comparative Study Of Chinese And American Address Terms, Shiqi Hao, Shaoan Zhang, Fan Zhu Oct 2008

A Comparative Study Of Chinese And American Address Terms, Shiqi Hao, Shaoan Zhang, Fan Zhu

Journal of Praxis in Multicultural Education

In cross-cultural situations, choices of address terms often reflect cultural differences. Although a good number of studies have discussed address terms in mono-linguistic settings, literature directly related to cross-cultural address terms is scarce. The current study intends to investigate common forms of address terms in Chinese and American cultures. Two hypotheses are examined: 1) Differences between Americans and Chinese in their choices of address terms are governed by cultural norms such as politeness, as well as by contexts or styles, and 2) The Chinese students in the U.S., who are undergoing the process of assimilation and acculturation, tend to accommodate …


Inside Unlv, Diane Russell, Shane Bevell, Jennifer Vaughan Oct 2008

Inside Unlv, Diane Russell, Shane Bevell, Jennifer Vaughan

Inside UNLV

No abstract provided.


Mojave Applied Ecology Notes Fall 2008, Alice Miller, Joshua Hoines, Scott R. Abella Oct 2008

Mojave Applied Ecology Notes Fall 2008, Alice Miller, Joshua Hoines, Scott R. Abella

Mojave Applied Ecology Notes

Effects of wildfires in Joshua Tree National Park, Blackbrush masting volunteer seed collection effort, new book chapter on Mojave revegetation, Natural Areas Association presentations.


Unlv Magazine, Holly Ivy De Vore, Tony Allen, Barbara Cloud, Erin O'Donnell, Matthew K. Jacobsen, Gian Galassi, Michelle Mouton, Afsha Bawany, Shane Bevell Oct 2008

Unlv Magazine, Holly Ivy De Vore, Tony Allen, Barbara Cloud, Erin O'Donnell, Matthew K. Jacobsen, Gian Galassi, Michelle Mouton, Afsha Bawany, Shane Bevell

UNLV Magazine

No abstract provided.


A Study Of The Biblical Worldview Of K-12 Christian School Educators, Mark Kelly Wood Oct 2008

A Study Of The Biblical Worldview Of K-12 Christian School Educators, Mark Kelly Wood

Doctoral Dissertations and Projects

Abstract Mark K. Wood. A STUDY OF THE BIBLICAL WORLDVIEW OF K-12 CHRISTIAN SCHOOL EDUCATORS. (Under the direction of Dr. Ellen Lowrie Black) School of Education, November, 2008. This study was designed to investigate the influence of six factors on the biblical Christian worldview of Christian school educators as measured by The Nehemiah Institute’s PEERS (2003) worldview assessment. The study sample consisted of 141 Christian school educators from six different Christian schools; three Association of Christian Schools International (ACSI) located in Idaho, and three Association of Classical & Christian Schools (ACCS) located in Idaho, Ohio, and Pennsylvania. A causal-comparative design …


Personality Characteristics Of Counseling Students At A Midwest Evangelical Seminary As Correlates Of Success, Satisfaction, And Self-Perceived Effectiveness, Keith Edward Marlett Oct 2008

Personality Characteristics Of Counseling Students At A Midwest Evangelical Seminary As Correlates Of Success, Satisfaction, And Self-Perceived Effectiveness, Keith Edward Marlett

Doctoral Dissertations and Projects

his study examined the question of how well personality traits as assessed by the MMPI-2 (clinical and L, F, K validity scales) and the NEO PI-R (domain scales) predict useful post-graduation markers of success in Master's level counselor education students. The subjects were 74 graduates of a seminary counselor education program in the Midwest. Participants completed the MMPI-2 (first 370 questions) and the NEO PI-R prior to admission and a post-graduation self-report questionnaire. Significant correlation between several personality traits and post-graduation markers of success emerged, but after Bonferroni adjustment, did not retain statistical significance and are therefore noted as trends …


Improving Student Engagement: Use Of The Interactive Whiteboard As An Instructional Tool To Improve Engagement And Behavior In The Junior High School Classroom, Georgia Lyn Morgan Oct 2008

Improving Student Engagement: Use Of The Interactive Whiteboard As An Instructional Tool To Improve Engagement And Behavior In The Junior High School Classroom, Georgia Lyn Morgan

Doctoral Dissertations and Projects

This study examined the impact of interactive whiteboard use on student engagement and appropriate at-task behaviors of junior high school students. Two hundred twenty-six students at two public schools in northeast Florida were observed during the second quarter of the school year. Data were collected using an at-task checklist, and students completed an attitude survey regarding their perception of their own engagement and enjoyment with interactive whiteboard use. Significant differences were noted in student behavior between instruction without interactive whiteboard use and instruction with interactive whiteboard use. No significant correlations were found between the variables gender and ethnicity and improved …


Rethinking The Digital Remix: Mashups And The Metaphysics Of Sound Recording, David J. Gunkel Oct 2008

Rethinking The Digital Remix: Mashups And The Metaphysics Of Sound Recording, David J. Gunkel

Faculty Articles, Papers, and Other Scholarship

Critical evaluations of audio mash-ups and remixes tend to congregate around two poles. On the one hand, these often clever recombinations of recorded music are celebrated as innovative and creative interventions in the material of bland commodity culture. On the other hand, they are often reviled as derivative, inauthentic, and illegal because they do nothing more than appropriate and reconfigure the intellectual property of others. This essay does not side with either position but identifies and critiques the common understanding and fundamental assumptions that make these two, opposed positions possible in the first place. The investigation of this matter is …


The Economic Value Of Water Quality, W. Kip Viscusi, Joel Huber, Jason Bell Oct 2008

The Economic Value Of Water Quality, W. Kip Viscusi, Joel Huber, Jason Bell

Vanderbilt Law School Faculty Publications

Stated preference values for water quality ratings based on the US Environmental Protection Agency National Water Quality Inventory ratings provide an operational basis for benefit assessment. Iterative choice survey results for a very large, nationally representative, Web-based panel imply an average valuation of $32 for each percent increase in lakes and rivers in the region for which water quality is rated “Good.” Valuations are skewed, with the mean value more than double the median. Sources of heterogeneity in benefit values include differences in responses to average water quality information and the base level of water quality. Conjoint estimates are somewhat …


Heightened Enablement In The Unpredictable Arts, Sean B. Seymore Oct 2008

Heightened Enablement In The Unpredictable Arts, Sean B. Seymore

Vanderbilt Law School Faculty Publications

A bedrock principle of patent law is that an applicant must sufficiently disclose the invention in exchange for the right to exclude. The essential facet of the disclosure requirement is enablement, which compels a patent applicant to enable a person having ordinary skill in the art (PHOSITA) how to make and use the full scope of the claimed invention without undue experimentation. Enablement problems may arise when the applicant claims an invention broadly with a dearth of supporting data or examples. This is problematic in unpredictable fields like chemistry because a PHOSITA often needs a specific and detailed teaching in …


Resonance Raman Spectroscopic Studies Of Hydroperoxo Derivatives Of Cobalt-Substituted Myoglobin, Piotr J. Mak, James R. Kincaid Oct 2008

Resonance Raman Spectroscopic Studies Of Hydroperoxo Derivatives Of Cobalt-Substituted Myoglobin, Piotr J. Mak, James R. Kincaid

Chemistry Faculty Research and Publications

Recent progress in generating and stabilizing reactive heme protein enzymatic intermediates by cryoradiolytic reduction has prompted application of a range of spectroscopic approaches to effectively interrogate these species. The impressive potential of resonance Raman spectroscopy for characterizing such samples has been recently demonstrated in a number of studies of peroxo- and hydroperoxo-intermediates. While it is anticipated that this approach can be productively applied to the wide range of heme proteins whose reaction cycles naturally involve these peroxo- and hydroperoxo-intermediates, one limitation that sometimes arises is the lack of enhancement of the key intraligand ν(O–O) stretching mode in the native …