Digital Commons Network^™

Mechanistic Studies On The Electrochemistry Of Glutathione And Homocysteine, Olufemi Oyesanya

Theses and Dissertations

This research work has investigated the electrochemistry of glutathione (GSH)and homocysteine (HCSH) in order to develop sensors for these biological thiols.Ru(bpy)₃³⁺ and IrCl₆²⁻ have been used as mediators for the electrooxidation of GSH andHCSH because direct oxidation of these thiols is slow at most conventional electrodes.The electrochemical detection of GSH and HCSH has been pursued because of their biological roles.

Concerted proton electron transfer (CPET) and stepwise proton electron transfer(PT/ET) pathways have been observed in the electrooxidation of GSH and HCSH.Oxidation of GSH by Ru(bpy)₃³⁺ carried out in deuterated and undeuterated buffered (pH= pD …

The Current Volume 18 : Issue 25, Nova Southeastern University

Student Newspapers

No abstract provided.

The Collegian (2008-04-21), Isis Lopez

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 60, No. 27

The Free Press Vol. 39, No. 21, 04-21-2008, Sarah Trent

Free Press, The

Making the list - Uncovering the budget - 4th annual Thinking Matters symposium - Words + Images published without images - The economy $ucks (Part 2 of 3) - Darfur refugee says “enough” isn’t enough - Students lay down their arms, and their bodies - News - Campus Events - Perspectives - Breaking Tradition: Personal Politics - Letter From Your Student Body President - From the Right: Corporate world is not the enemy - Arts & Entertainment - Students protest Husky Film Fest - The Bachelor of Fine Arts student show (Part 1 of 2) - Not your grandmother's classical …

A Central Function For Perlecan In Skeletal Muscle And Cardiovascular Development, Jason J. Zoeller, Angela Mcquillan, John Whitelock, Shiu-Ying Ho, Renato V. Iozzo

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Perlecan's developmental functions are difficult to dissect in placental animals because perlecan disruption is embryonic lethal. In contrast to mammals, cardiovascular function is not essential for early zebrafish development because the embryos obtain adequate oxygen by diffusion. In this study, we use targeted protein depletion coupled with protein-based rescue experiments to investigate the involvement of perlecan and its C-terminal domain V/endorepellin in zebrafish development. The perlecan morphants show a severe myopathy characterized by abnormal actin filament orientation and disorganized sarcomeres, suggesting an involvement of perlecan in myopathies. In the perlecan morphants, primary intersegmental vessel sprouts, which develop through angiogenesis, fail …

Expression Of Nicotinic Acetylcholine Receptor Mrna As A Function Of Age In Whole Hippocampus Preparations From Wistar Rats, Kasey C. Welch

Theses and Dissertations

Whole hippocampus preparations, isolated bilaterally, from untreated Wistar rats at various ages (10-90 days old) were analyzed for the mRNA expression of the alpha 2, alpha 3, alpha 4, alpha 5, alpha 7, beta 2, beta 3, and beta 4 neuronal nicotinic acetylcholine receptor subunits. To do so, RNA was isolated from acutely isolated hippocampal samples, converted to cDNA by means of a reverse transcription reaction, then analyzed with quantitative real-time PCR to determine the relative levels of the mRNAs the cells were expressing at the age when the samples were obtained. The relative expression of the levels of RNA …

On The Role Of Mitochondria In The Regulation Of Calcium In Motor Nerve Terminals During Repetitive Stimulation, Luis E. Garcia-Chacon

Open Access Dissertations

During repetitive stimulation of motor nerve terminals, mitochondrial Ca2+ uptake limits increases in free cytosolic [Ca2+] and helps ensure faithful neuromuscular transmission. Changes in cytosolic [Ca2+] and in mitochondrial [Ca2+] as well as changes in mitochondrial membrane potential (Psi m) were studied in mouse motor nerve terminals using Ca2+ sensitive indicator and potentiometric dyes, respectively. Trains of action potentials (APs) at 50 to 100 Hz produced a rapid increase in mitochondrial [Ca2+] followed by a plateau which usually continued beyond the end of stimulation. After stimulation, mitochondrial [Ca2+] decayed back to baseline over the course of tens of seconds to …

Development Of An In Vivo Fundus Imaging And Retinal Optical Coherence Tomography System For The Mouse, Omer Pars Kocaoglu

Open Access Dissertations

The purpose of this project is to develop a retinal imaging system suitable for routine examination or screening of mouse models that acquires fundus and Optical Coherence Tomography (OCT) images. The imaging system is composed of a digital camera with an objective for biomicroscopic examination of the fundus, an OCT interferometer, an OCT beam delivery system designed for the mouse eye, and a mouse positioning stage. The image acquisition is controlled with software that displays the fundus and OCT images in real-time, and allows the user to control the position of the OCT beam spot on the fundus image display. …

Angiographic Assessment Of Flow Divertors As Treatment For Cerebral Aneurysms: Results In The Rabbit Elastase-Induced Aneurysm Model, Chandramouli Sadasivan

Open Access Dissertations

Cerebral aneurysms are abnormal focal dilations of the cerebral vasculature that may rupture and cause a hemorrhagic stroke. More than a decade after seminal experimental studies showed the feasibility of successfully treating cerebral aneurysms by flow diversion, the potential of this modality is gradually being recognized in the clinical arena. A flow divertor is a metallic meshed tube that has its porosity (ratio of metal-free surface area to total surface area) and pore density (number of pores per unit surface area) optimized to facilitate occlusion of aneurysms. An appropriately designed flow divertor severely attenuates the flow exchange between the parent …

Occurrence And Fate Of Pesticides In Four Contrasting Agricultural Settings In The United States, Gregory V. Steele, Henry M. Johnson, Mark W. Sandstrom, Paul D. Capel, Jack E. Barbash

United States Geological Survey: Staff Publications

Occurrence and fate of 45 pesticides and 40 pesticide degradates were investigated in four contrasting agricultural settings—in Maryland, Nebraska, California, and Washington. Primary crops included corn at all sites, soybeans in Maryland, orchards in California and Washington, and vineyards in Washington. Pesticides and pesticide degradates detected in water samples from all four areas were predominantly from two classes of herbicides—triazines and chloroacetanilides; insecticides and fungicides were not present in the shallow ground water. In most samples, pesticide degradates greatly exceeded the concentrations of parent pesticide. In samples from Nebraska, the parent pesticide atrazine [6-chloro-N-ethyl-N′-(1-methylethyl)-1,3,5-triazine-2,4- diamine] was about the same concentration …

The Murray Ledger And Times, April 19, 2008, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Volume 43 - Issue 23 - Friday, April 18, 2008, Rose Thorn Staff

The Rose Thorn Archive

The Rose Thorn, Rose-Hulman's independent student newspaper.

Sixteenth Annual Student Research And Creative Activities Symposium - April 18, 2008, Symposium Steering Committee

Student Research and Creative Activities Symposium 1993-2018

Participants - College of Arts and Sciences, College of Business and Management, College of Education, Graduate College, University Honors Program, McNair Scholars Program

Reporter - April 18th 2008, Rit Reporter Staff

University Publications

No abstract provided.

The Tiger Vol. 102 Issue 12 2008-04-18, Clemson University

Tiger Newspapers

No abstract provided.

Altered Signaling By Fibronectin Fragments Creates A Potent Chondrolytic State, Lei Ding

Theses and Dissertations

It has been shown that fibronectin fragments (Fn-fs) greatly augment cartilage proteoglycan (PG) depletion by up-regulating matrix metalloproteinases (MMPs) and catabolic cytokines. The activities of three different Fn-fs have been studied: an amino terminal 29-kDa which is most potent with a weak affinity to the α5β1, integrin, the receptor for native fibronetin (Fn); a 50-kDa gelatin-binding Fn-f with no known interaction with Fn receptor; and a 140-kDa Fn-f which is the least potent and has a RGDS sequence which can bind to the α5β1 integrin. Confocal studies showed that Fn-fs caused diffusion of α5β 1 integrin clusters which were seen …

Light Induced Changes In The Photoreceptor Outer Segments, Vikram Palamalai

Theses and Dissertations

Light induced retinal degeneration in animals has been used to study human retinal degenerative disorders. Apoptosis is the final common pathway for photoreceptor degeneration in both the experimental model and human disease but the mechanism is unknown. Oxidative stress plays a role because antioxidants have been shown to be protective against experimental degeneration. Inhibitors of nitric oxide synthases (NOS) are also protective suggesting a role for nitric oxide. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) a key enzyme in glycolysis was identified as one of the proteins undergoing significant nitration in our studies on light induced retinal degeneration. This study focuses on the changes …

Regulation Of Pro-Inflammatory Responses By Ligands Of The Nuclear Receptor Pparγ, Andrew P. Woster

Theses and Dissertations

Inflammation-related neurotoxicity is evident in a number of different models neurodegenerative conditions, including Alzheimer's and Parkinson's diseases, Multiple Sclerosis, and HIV-associated dementia. Peroxisome proliferator-activated receptor gamma (PPARγ) agonists inhibit a number of select pro-inflammatory changes in models of CNS and systemic inflammation. Recent reports suggest that these anti-inflammatory effects are due to mechanisms other than canonical nuclear receptor-mediated transcriptional alteration. Results reported here demonstrate that rosiglitazone, a PPARγ-activating thiazolidinedione, decreases tumor necrosis factor α (TNFα) secretion in both primary microglia and the monocytic cell line, THP-1. Cells were pretreated with various PPARγ ligands, including rosiglitazone, prior to stimulation with lipopolysaccharide …

Central Florida Future, Vol. 40 No. 41, April 18, 2008

Central Florida Future

A call to help; Summit looks at U.S. economy; Speaker addresses Fla. conservation; Trying to find balance.

Lonely Sounds: Recorded Popular Music And American Society, 1949–1979, Chris R. Rasmussen

Department of History: Dissertations, Theses, and Student Research

Abstract: Lonely Sounds: Popular Recorded Music and American Society, 1949-1979 Lonely Sounds: Popular Recorded Music and American Society, 1949-1979 examines the relationship between the experience of listening to popular music and social disengagement. It finds that technological innovations, the growth of a youth culture, and market forces in the post-World War II era came together to transform the normal musical experience from a social event grounded in live performance into a consumable recorded commodity that satisfied individual desires. The musical turn inward began in the late 1940s. Prior to the postwar era, the popular music experience was communal, rooted in …

Sandspur, Vol 114, No 22, April 18, 2008, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

The Murray State News, April 18, 2008, The Murray State News

Murray State University Collection

No abstract provided.

Neural Characteristics Of Affectionate Communicators: Trait Affection And Asymmetry In The Prefrontal Cortex, Robert Joel Lewis

Theses

Individual differences in thresholds for affectionate communication should be reflected by differences in neurological structure and function. A theoretical schema from several overlapping literatures including evolutionary psychology, social neuroscience, fundamental personality, and communication are examined to make the case that high-affection communicators have greater relative electrical activity in the left prefrontal cortex (PFC) versus the right PFC reflected in asymmetrical baseline EEG recordings. Participants (N=16) reported trait-affection levels using Floyd?s (2002) TAS-G, which measures an individual?s threshold for expressing affection. Participants? baseline electrical activity was then recorded. Asymmetry was operationalized as the difference between microvolt (μV) values of laterally opposed …

Toward A New Perspective In Literary Criticism: Transgenerational Psychoanalysis And Anasemic Procedures, Gustav Arnold

Theses and Dissertations

This dissertation—Toward a New Perspective in Literary Criticism: Transgenerational Psychoanalysis and Anasemic Procedures"—is a contribution to literary criticism. It offers a new perspective in psychoanalytical criticism on how characters in literary narratives can be interpreted. By examining key concepts in psychoanalysis, which have been used in the humanities for decades, the present inquiry draws on transgenerational psychology, as elaborated by German and French theorists, and anasemic interpretations generated by M. Torok and N. Abraham's psychoanalytical approach. Based on the assumption that a character's psychic life is determined by factors that cannot be confined to intrapsychic processes alone, the transgenerational perspective …

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for April 17, 2008

Commonwealth Times 2008-04-17

Commonwealth Times, 1969-

No abstract provided.

Prospectus, April 17, 2008, Kathleen Serino, Briana Stodden, Chuck Shepherd, Aaron Geiger, Beth Voigt, Jason Hardimon, Shane Swearingen, Gavin J. Dow

Prospectus 2008

No abstract provided.

Ua12/2/1 College Heights Herald, Vol. 83, No. 48, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. Articles:

• Siders, Neil. Student Government Association Bill Pushes for Free Music – Ruckus
• Coulter, Amber. No Horsing Around: Pre-Veterinary Students – Agriculture, Jenks Britt
• Day, Michelle. Students May Suffer from Federal Loan Cuts – Student Financial Aid
• Ryan, Eileen. Barak Obama Campaign Opens Local Office – Elections
• Powers, Mary. A Thousand Words – Ting Ting Zhao, Yu-Pin Cheng, Po-Chien Cheng, International Students
• Chester L. Davis, Former Professor Dies at 84
• Student Charged with Indecent Exposure – Marreon Allen
• Assault Reported in Cravens Library – Addison James, William Pape
• Rowell, …

R.I.T. News & Events - April 17, 2008, University News Services, Rochester Institute Of Technology

University Publications

High Falls Film Festival to showcase students work; State gives $12M to Golisano Institute; McKenzie selected as 2008 Convocation speaker;Big Shot to shine on Erie Canal; NTIDs Dyer Arts hosts Rochester Artech 2008; Saunders College lauds Hammer; Border Patrol images,human essence focus of photo exhibits and discussion; Palmer honored as engineer of the year; News media talk kicks off lecture series; Communication conference $1.12 million for NTID draws students from four states;

Montana Kaimin, April 17, 2008, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.