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Governing Guns, Opposing Opium: A Theory Of Internationally Regulated Goods, Asif Efrat

Cornell Law Faculty Working Papers

The paper examines a significant phenomenon overlooked by the trade literature: internationally regulated goods. Contrary to the general trend of trade liberalization, specific goods, such as drugs, small arms, and antiquities, have come under increasing international control in recent decades through a set of global regulatory agreements. I argue that these goods are unique in that they involve transnational negative externalities. Whereas certain countries benefit from the trade in these goods, the trade inflicts negative effects on other countries. Examples of such negative externalities include fatalities and refugee flows resulting from rampant gun violence, high crime rates associated with widespread …

Results Of A Twenty-Two Year Old Progeny Test Of A Pinus Sylvestris Plantation In Eastern Nebraska, Adam D. Rupe, Tala Awada

RURALS: Review of Undergraduate Research in Agricultural and Life Sciences

The goal of this study was to examine the performance and adaptability of a 22-year-old Pinus sylvestris L. (Scots pine) full-sibling progeny plantation representing genetic material from seven European countries (Spain, France, Russia, Ex-Yugoslavia, Italy, Greece, and Germany), to the Great Plains environment. The study site was located at the University of Nebraska Agricultural Research and Development Center near Mead, NE. A total of 92 individuals originating from 23 crosses were studied for the following growth parameters: specific leaf area (SLA, cm²g^-1), needle length (cm), canopy width (m), and tree height (m). Analysis of variance and …

Is A Chest Tube Necessary Prior To Air Medical Transport Of Patients With Pneumothorax?, Gregory Pirkl, Darren Braude

Undergraduate Medical Student Research

Objective: It is conventionally thought that patients with pneumothoraces (PTX) require tube thoracostomy prior to air medical transport (AMT), especially in un-pressurized rotor-wing aircraft, to prevent deterioration from expansion of the pneumothorax and possible development of tension pneumothorax. We hypothesized that patients with pneumothorax(ces) transported without prior tube thoracostomy tolerate AMT without serious deterioration. Methods: We conducted a retrospective case-series of trauma patients transported via helicopter with radiographically confirmed PTX between September 2002 and September 2005. Charts were evaluated for signs of deterioration including hypotension, hypoxemia, respiratory distress, intubation, needle thoracostomy or cardiac arrest during transport. In addition, duration of …

The Murray State News, August 22, 2008, The Murray State News

Murray State University Collection

No abstract provided.

The Bees Of Greater Puerto Rico (Hymenoptera: Apoidea: Anthophila), Julio A. Genaro, Nico M. Franz

Insecta Mundi

The bee fauna of the Greater Puerto Rico area was studied. A review of the previous relevant studies is presented. An annotated catalog and information about the origin and distributional patterns are also provided. Thirty-nine species of bees occur in Puerto Rico and adjacent islands. This fauna is composed of four elements: exclusive Puerto Rican endemics (26.5%); Antillean endemics occurring on multiple islands (76.5%); continental species that have also colonized the Antilles (23.5%); and species introduced through human activity (12.8%). The bee fauna was both low in its diversity and showed the highest level of disharmony in relation to other …

The Tonality, Timbre, Affect, And Mood Of Postmodern Drama, Or, Blues Music In Tennessee Williams's A Streetcar Named Desire, Matthew L. Wohlgemuth

Electronic Theses and Dissertations

No abstract provided.

The Echo: August 22, 2008, Taylor University

2008-2009 (Volume 96)

Off-Campus housing comes closer to home – Taylor ranked No. 1 again – Get connected – TU welcomes new staff – Carpe walké: Seize the walk – Top nine: [Things I wish I knew as a freshman] – Summer’s seven—The $50 I spent at the movies – You seemed more pious on Facebook – Putting the ‘chool’ back in ‘school’ – Wanted: Your brains – Quite the balancing act – Men’s soccer hard at work in 2008 – Trojan Sports – Recruitment aims for athletic progress – Athlete of the Week

The Healthy Solitary Person, Laurel Lynn Shortell

Theses, Dissertations, and Projects

This thesis explored the concept of the healthy solitary person who prefers to spend time alone and pursue activities independently and whose independent way of life serves as a source of strength and pleasure. Despite the American ideal of the rugged individualist, the solitary person is often pathologized, seen as being in a transitional state, or not considered at all by much of the psychological literature and by American society at large. This paper examined the societal role played by solitude and drew from self psychology and object relations theory to answer the following question: how can a solitary lifestyle …

Gamma-Synuclein As A Marker Of Retinal Ganglion Cells, Irina Surgucheva, Alejandra D. Weisman, Jeffrey L. Goldberg, Alexander A. Shnyra, Andrei Surguchov

Faculty and Staff Publications

Purpose: Previous studies have described gamma-synuclein as a protein highly expressed in retinal ganglion cells (RGCs), and a loss of RGCs correlates with a downregulation of gamma-synuclein gene expression in glaucoma. Here we asked whether gamma-synuclein expression in the retina can be considered a specific marker of RGCs.

Methods: gamma-Synuclein expression was examined with immunohistochemistry in retinal sections from normal and glaucomatous human eyes. Primary cultures of RGCs from Sprague-Dawley rats purified by sequential immunopanning using a monoclonal antibody to Thy1-1, cultures of A7 immortalized optic nerve astrocytes from newborn rats, and the immortalized RGC-5 cell line were studied using …

The Bg News August 22, 2008, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. August 22, 2008. Volume 99-Issue 1.

Identification Of Mitogen-Activated Protein Kinase Docking Sites In Enzymes That Metabolize Phosphatidylinositols And Inositol Phosphates, Marcos Sosa, Kevin Caldwell, Colin Buckley

Undergraduate Medical Student Research

Background: Reversible interactions between the components of cellular signaling pathways allow for the formation and dissociation of multimolecular complexes with spatial and temporal resolution and, thus, are an important means of integrating multiple signals into a coordinated cellular response. Several mechanisms that underlie these interactions have been identified, including the recognition of specific docking sites, termed a D-domain and FXFP motif, on proteins that bind mitogen-activated protein kinases (MAPKs). We recently found that phosphatidylinositol-specific phospholipase C-γ1 (PLC-γ1) directly binds to extracellular signal-regulated kinase 2 (ERK2), a MAPK, via a D-domain-dependent mechanism. In addition, we identified D-domain sequences in several other …

An Sp1/Sp3 Binding Polymorphism Confers Methylation Protection, Yanis A. Boumber, Yutaka Kondo, Xuqi Chen, Lanlan Shen, Yi Guo, Carmen Tellez, Marcos R H Estécio, Saira Ahmed, Jean-Pierre J. Issa

Faculty, Staff and Student Publications

Hundreds of genes show aberrant DNA hypermethylation in cancer, yet little is known about the causes of this hypermethylation. We identified RIL as a frequent methylation target in cancer. In search for factors that influence RIL hypermethylation, we found a 12-bp polymorphic sequence around its transcription start site that creates a long allele. Pyrosequencing of homozygous tumors revealed a 2.1-fold higher methylation for the short alleles (P<0.001). Bisulfite sequencing of cancers heterozygous for RIL showed that the short alleles are 3.1-fold more methylated than the long (P<0.001). The comparison of expression levels between unmethylated long and short EBV-transformed cell lines showed no difference in expression in vivo. Electrophorectic mobility shift assay showed that the inserted region of the long allele binds Sp1 and Sp3 transcription factors, a binding that is absent in the short allele. Transient transfection of RIL allele-specific transgenes showed no effects of the additional Sp1 site on transcription early on. However, stable transfection of methylation-seeded constructs showed gradually decreasing transcription levels from the short allele with eventual spreading of de novo methylation. In contrast, the long allele showed stable levels of expression over time as measured by luciferase and approximately 2-3-fold lower levels of methylation by bisulfite sequencing (P<0.001), suggesting that the polymorphic Sp1 site protects against time-dependent silencing. Our finding demonstrates that, in some genes, hypermethylation in cancer is dictated by protein-DNA interactions at the promoters and provides a novel mechanism by which genetic polymorphisms can influence an epigenetic state.

A Generic Approach And Framework For Managing Complex Information, Essam Mansour

Doctoral

Several application domains, such as healthcare, incorporate domain knowledge into their day-to-day activities to standardise and enhance their performance. Such incorporation produces complex information, which contains two main clusters (active and passive) of information that have internal connections between them. The active cluster determines the recommended procedure that should be taken as a reaction to specific situations. The passive cluster determines the information that describes these situations and other descriptive information plus the execution history of the complex information. In the healthcare domain, a medical patient plan is an example for complex information produced during the disease management activity from …

The Daily Gamecock, Thursday, August 21, 2008, University Of South Carolina, Office Of Student Media

August

No abstract provided.

Embodied Practice : Do Social Work Therapists Explore Client Strengths As Expressed In The Lived Experience Of The Body?, Duncan Nichols

Theses, Dissertations, and Projects

This study was undertaken to explore how seven social work therapists attend to client strengths, with an emphasis on embodied experience and embodied strengths where competency and resourcefulness are experienced. Besides asking questions about the obvious markers of a person's physical experience (hobbies, work, etc.), questions about the psychoanalytic concept of body-self and attributes of certain popularized mind/body approaches or techniques social work therapists may use were also posed. Workers, whose practices are in community mental health, inpatient psychiatry, medical and private practice settings, provided experience-near narrative data. Major findings were workers' belief in the clinical value of using a …

A Survey Of Clinicians' Use Of Touch And Body Awareness In Psychotherapy, Anastasia D. Mcrae

Theses, Dissertations, and Projects

A national purposive expert convenience sample of approximately 164 licensed, practicing mental health professionals responded to an anonymous online survey regarding the use of touch and body awareness in their treatment with clients. This study sought to answer the question of the effects of training, whether during the course of study to become a mental health professional or in a specific formalized body-oriented modality, on the attitudes and behavior of clinicians towards their use of touch and body awareness in psychotherapy treatment. The findings showed that training in the use of touch or body awareness does influence positive attitudes toward …

Using Simulation Optimization To Construct Efficient Screening Strategies For Cervical Cancer, Christodoulos Foufoulides

Theses and Dissertations

Cervical cancer is the second most common type of cancer in women worldwide. Because cervical cancer is usually asymptomatic until the disease is in its advanced stages, cervical screening is of central importance towards combating cervical cancer. Alternative screening strategies are evaluated from an economic point of view through cost-effectiveness analysis. In the literature however, studies perform cost-effectiveness analysis on a limited number of de facto or predetermined screening policies. At present, no attempt has been made to construct efficient screening strategies through optimization, before cost-effectiveness analysis is applied. In this study simulation optimization is used to construct efficient screening …

Bolen Faculty Recital Series: August 21, 2008, Sarah Gentry, Paul Borg, Tuyen Tonnu

School of Music Programs

This is the first program of the 2008-2009 season.

Kemp Recital Hall

August 21, 2008

Thursday Evening

7:30 p.m.

Illinois State University Report, August 21, 2008, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

Flavonoids As Modulators Of Amyloid Precursor Protein Metabolism And Alzheimer Disease Pathology, Kavon Rezai-Zadeh

USF Tampa Graduate Theses and Dissertations

Alzheimer disease (AD) is a progressive neurodegenerative disorder pathologically characterized by deposition of ß-amyloid (Aß) peptides as plaques in the brain. Central to this AD pathology is mismetabolism of the amyloid precursor protein (APP). Recent studies suggest that flavonoids, a class of secondary plant metabolites, may be useful for the prevention and treatment of a variety of neurodegenerative diseases. The studies detailed herein, investigate the ability of two such classes of flavonoids, green tea derived catechins and 5,7-dihydroxyflavones, to modulate APP metabolism in "Swedish" mutant APP (APP_sw) models of AD. Studies showed that green tea derived (-)-epigallocatechin-3-gallate (EGCG) …

Energizing Renewable Technology: Policy, Permitting & Politics, Kathleen Drakulich

UNLV Renewable Energy Symposium

The 2008 UNLV Renewable Energy Symposium was presented by the Office of Strategic Energy Programs and co-sponsored by the Division of Research and Graduate Studies on August 20, 2008 on the UNLV campus.

The event focused on renewable energy production in Nevada, the US Southwest, and renewable research projects nationwide. It was a great opportunity for anyone working on renewable projects to collaborate with others in this field and exchange information. Over 230 individuals attended the event this year.

The Way We Speak Affects Our Reality : Why Speaking From The Values Of Racial Justice Begins The Creation Of A Racially Just World, Katherine Alice Hornowski

Theses, Dissertations, and Projects

This theoretical study is a declaration that speaking and acting from a place outside of opposition is powerful in creating a more racially just world. To explore this declaration, this thesis first reviews the language used in racial justice work today and the values that underlie this language. It then examines a different way of framing, one that seeks to come from a value system of acceptance of reality and working towards a more racially just world, rather than a value system rooted in opposition to reality and working against injustice. There is little to no literature on this topic. …

Parental Death : Grieving Loss Of Life While Sustaining A Relationship, Maisie Lasher Ketron

Theses, Dissertations, and Projects

This study explored how an adult whose parent died during childhood understands their ongoing relationship with that parent and whether rituals or practices are integral to observing that ongoing relationship. Psychodynamic theory first examined the grieving process as a linear, time-limited experience. The field of grief and bereavement studies has become polarized around traditional psychodynamic theorists who have examined pathological bereavement and post-modern continuing bonds theorists whose focus is the nature of the ongoing relationship to the deceased. There is limited research exploring bereavement in childhood and particularly the process of mourning and relating to the deceased parent over time. …

Nucleoside Diphosphate Kinase Isoforms Associated With Mitochondria In Rat And Human., Dean Allen Frolich

Theses and Dissertations

Nucleoside diphosphate kinases (NDP kinases) are a family of enzymes that transfer the gamma-phosphate group from a NTP (nucleoside triphosphate) to a NDP (nucleoside diphosphate). The reaction follows a ping-pong mechanism in which the enzyme is transiently phosphorylated on a conserved histidine residue. In the cell, activity appears to be ubiquitous as it is associated with the cytosol, nucleus, mitochondria and plasma membrane. NDP kinase enzymatic activity has been demonstrated in a variety of tissues. The classical role proposed for NDP kinase in mitochondrial matrix is the transfer of a phosphoryl group from GTP (produced in the TCA cycle) to …

Development Of A Definition, Classification System, And Model For Cultural Geology., Lloyd W. Mitchell Iii

Theses and Dissertations

The concept for this study is based upon a personal interest by the author, an American Indian, in promoting cultural perspectives in undergraduate college teaching and learning environments. Most academicians recognize that merged fields can enhance undergraduate curricula. However, conflict may occur when instructors attempt to merge social science fields such as history or philosophy with geoscience fields such as mining and geomorphology. For example, ideologies of Earth structures derived from scientific methodologies may conflict with historical and spiritual understandings of Earth structures held by American Indians. Specifically, this study addresses the problem of how to combine cultural studies with …

The Spinnaker Vol. 32 No. 3, University Of North Florida

Spinnaker

Student newspaper for the UNF community.

Staphylococcus Aureus Pbp4 Is Essential For Β-Lactam Resistance In Community-Acquired Methicillin-Resistant Strains, G Memmi, S R. Filipe, M G. Pinho, Z Fu, Ambrose Cheung

Dartmouth Scholarship

Recent cases of infections caused by community-acquired methicillin-resistant Staphylococcus aureus (MRSA) (CA-MRSA) strains in healthy individuals have raised concerns worldwide. CA-MRSA strains differ from hospital-acquired MRSAs by virtue of their genomic background and increased virulence in animal models.

National Clean Energy Panel Presentations

National Clean Energy Summit

Panel presentations, 206 PowerPoint slides

Characterization Of Escherichia Coli Populations From Gulls, Landfill Trash, And Wastewater Using Ribotyping, M. Nelson, Stephen H. Jones, C. Edwards, J. C. Ellis

Jackson Estuarine Laboratory

Due to their opportunistic and gregarious nature, gulls may be important reservoirs and vectors for anthropogenically derived fecal pathogens in coastal areas. We used ribotyping, a genotypic bacterial source tracking method, to compare populations of Escherichia coli among herring gulls Larus argentatus, great black-backed gulls L. marinus, wastewater, and landfill trash in New Hampshire and Maine, USA. Concentrations of E. coli in gull feces varied widely among individuals, but were generally high (6.0 × 101 to 2.5 × 109 g–1 wet weight). Of 39 E. coli isolates from L. argentatus, 67% had banding patterns that were ≥90% similar to those …

Understanding Animal Welfare, David Fraser

Assessment of Animal Welfare Collection

In debates about the welfare of animals, different people have tended to emphasize different concerns. Some emphasize the basic health and functioning of animals, especially freedom from disease and injury. Others emphasize the "affective states" of animals – states like pain, distress and pleasure that are experienced as positive or negative. Others emphasize the ability of animals to live reasonably natural lives by carrying out natural behaviour and having natural elements in their environment. These concerns constitute different criteria that people use to assess animal welfare. The criteria overlap substantially but are sufficiently independent that the single- minded pursuit of …