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The Guardian, May 30, 2007, Wright State University Student Body

The Guardian Student Newspaper

Twenty-six page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

The Kinesin-13 Proteins Kif2a, Kif2b, And Kif2c/Mcak Have Distinct Roles During Mitosis In Human Cells, Amity L. Manning, Neil J. Ganem, Samuel F. Bakhoum, Michael Wagenbach, Linda Wordeman, Duane A. Compton

Dartmouth Scholarship

The human genome has three unique genes coding for kinesin-13 proteins called Kif2a, Kif2b, and MCAK (Kif2c). Kif2a and MCAK have documented roles in mitosis, but the function of Kif2b has not been defined. Here, we show that Kif2b is expressed at very low levels in cultured cells and that GFP-Kif2b localizes predominately to centrosomes and midbodies, but also to spindle microtubules and transiently to kinetochores. Kif2b-deficient cells assemble monopolar or disorganized spindles. Chromosomes in Kif2b-deficient cells show typical kinetochore-microtubule attachments, but the velocity of movement is reduced ∼80% compared with control cells. Some Kif2b-deficient cells attempt anaphase, but the …

Albumin-Binding Paracest Agents, M. Meser Ali, Mark Woods, Eul Hyun Suh, Zoltan Kovacs, Gyula Tircsó, Piyu Zhao, Vikram D. Kodibagkar, A. Dean Sherry

Chemistry Faculty Publications and Presentations

Lanthanide complexes (Eu³⁺, Gd³⁺ and Yb³⁺) of two different 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid tetraamide derivatives containing two (2) and four (3) O-benzyl-L-serine amide substituents were synthesized and their chemical exchange saturation transfer (CEST) and relaxometric properties were examined in the presence and absence of human serum albumin (HSA). Both Eu2 and Eu3 display a significant CEST effect from a single slowly exchanging Eu³⁺-bound water molecule, making these PARACEST complexes potentially useful as vascular MRI agents. Yb2 also showed a detectable CEST effect from both the Yb³⁺-bound water protons and the …

Faculty Institute On Teaching And Learning (Fitl) Presentations (2007), Fitl Conference

RIT Digital Archives

The speakers this year included not only your RIT colleagues, but we welcomed keynote speaker Steve Cohen and Dr. Stanley McKenzie. Day One featured a variety of concurrent sessions on a large number of subjects. Day Two was introduced by Lynn Wild and ended early in the afternoon.

Soybean Fgam Synthase Promoters Useful In Nematode Control: U.S. Patent No. Us 7,223,901 B2, Sally Ann Mackenzie, Zarir Vaghchhipawala

Department of Plant Pathology: Faculty Publications

The subject invention relates to nematode responsive domains obtained from soybean promoters for phosphoribosylformylglycinamidine ribonucleotide (FGAM) synthase paralogs. The nematode responsive domains can be used in promoters that are linked to heterologous DNA. Such constructs can be expressed in transfected or transformed soybean and used in the control of nematode infection of soybean.

Apres Le Deluge: Microbial Landscape Of New Orleans After The Hurricanes, Fred C. Dobbs

OES Faculty Publications

No abstract provided.

Parasites Alter Community Structure, Chelsea L. Wood, James E. Byers, Kathryn L. Cottingham, Irit Altman

Dartmouth Scholarship

Parasites often play an important role in modifying the physiology and behavior of their hosts and may, consequently, mediate the influence hosts have on other components of an ecological community. Along the northern Atlantic coast of North America, the dominant herbivorous snail Littorina littorea structures rocky intertidal communities through strong grazing pressure and is frequently parasitized by the digenean trematode Cryptocotyle lingua. We hypothesized that the effects of parasitism on host physiology would induce behavioral changes in L. littorea, which in turn would modulate L. littorea's influence on intertidal community composition. Specifically, we hypothesized that C. lingua …

Independent- May 29, 2007, Duncan Macnab

The Independent (1988-present)

No abstract provided.

Workshop On The Nuclear War Legacy To Be Held For College Professors, Sherry Wallace

News and Events (Discontinued Series)

No abstract provided.

Dielectrophoretic Tweezers For Examining Particle-Surface Interactions Within Microfluidic Devices, S W. Lee, Haibo Li, Rashid Bashir

Birck and NCN Publications

The authors present dielectrophoresis (DEP)-based tweezers that can be used to characterize the interactions between a particle and the surface it is attached to, within a microfluidic device. As a proof of concept, 5.4 mu m polystyrene beads functionalized by carboxyl group were attached on a bare and poly-L-lysine functionalized oxide surface. Negative dielectrophoresis force was generated using interdigitated electrodes and the peak dielectrophoresis voltage where the beads were repelled away from the surface was used to characterize the strength of interaction between the particle and the surface. Electric field and DEP force calculation were used to corroborate the measured …

May 28, 2007 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

'Architectural Gaits': Architectures As Technologies And Techniques, Katrine Lotz

Nordes Conference Series

Attempts to describe and define ‘the role of the architect’ or the notion of architecture ‘itself’, often inherit a displacement between the interests in processes and the interests in interpretations of, or preceptions for either the results as ‘good quality’ or for the practise as ‘good conduct’. They tend to produce rigid models of the design-process, sociologically reducing explanations or mere ethical judgements. (Lawson, Cuff, Lundequist, Effekt:42) With this blurred and blurring difference as a point of departure, the interest in the competencies and strategies performed in the processes gets difficult conditions. The quests for the essences of either ‘Architecture’ …

The Patient As Skilled Practitioner, Jacob Buur, Kyle Kilbourn

Nordes Conference Series

We challenge the limiting view imposed on interaction design by the concept of usability because we hope to bring more awareness of and sensitivity toward skilled practitioners to the forefront of the design process. This article draws upon empirical research examples of patients who ‘do’ home hemodialysis and asks what happens when patients are considered skilled practitioners rather than as victims? In this article we argue for a change of perspective, from users to skilled practitioners in the design of technological devices. We advocate to design tools for enskilment, allowing for a sense of empowerment.

2007 Rose-Hulman Institute Of Technology : One-Hundred And Twenty-Ninth Commencement, Rose-Hulman

Commencement Programs

No abstract provided.

Mechanisms Causing Ferric Staining In The Secondary Water System Of Brigham City, Utah, Robert Derring Wallace

Theses and Dissertations

Water from Mantua reservoir has, during some years, exhibited reddish-brown staining when used by Brigham City for irrigation. I propose that seasonal fluctuations in the reservoir chemistry create an environment conducive to dissolving iron from the iron-rich sediments, which subsequently precipitate during irrigation, resulting in a staining event. These conditions are produced by chemical and biological decomposition of organic matter, coupled with isolation of the hypolimnetic waters, which results in seasonal low concentrations of dissolved oxygen in these waters. Under these specific circumstances, anaerobic conditions develop creating a geochemical environment that causes iron and manganese reduction from Fe(III) to Fe(II) …

On The Green Vol. 37 No. 13 May 25, 2007, Gallaudet University

2001-2010

On the Green is an internal publication of Gallaudet College, which later became Gallaudet University. It notified employees of updates around the campus and in the broader community, including new construction and the establishment of new academic programs. Running until 2010, it was supplanted by various forms of online mass communications across multiple audiences.

Dicamba Resistance: Enlarging And Preserving Biotechnology-Based Weed Management Strategies, Mark Behrens, Nedim Mutlu, Sarbani Chakraborty, Razvan Dumitru, Wen Zhi Jiang, Bradley J. Lavallee, Patricia L. Herman, Thomas E. Clemente, Donald P. Weeks

Center for Plant Science Innovation: Faculty Publications

The advent of biotechnology-derived, herbicide-resistant crops has revolutionized farming practices in many countries. Facile, highly effective, environmentally sound, and profitable weed control methods have been rapidly adopted by crop producers who value the benefits associated with biotechnology-derived weed management traits. But a rapid rise in the populations of several troublesome weeds that are tolerant or resistant to herbicides currently used in conjunction with herbicide-resistant crops may signify that the useful lifetime of these economically important weed management traits will be cut short. We describe the development of soybean and other broadleaf plant species resistant to dicamba, a widely used, inexpensive, …

2007 Commencement Program, Whittier College

Commencement Programs

Whittier College's One Hundred Fourth Commencement, May 25, 2007

Commencement Address: The Honorable Antonio Villaraigosa, Mayor of City of Los Angeles

Supplement file includes Spring Honors Convocation, May 8, 2007

Crystal Structure Of Formate Dehydrogenase H: Catalysis Involving Mo, Molybdopterin, Selenocysteine, And An Fe4S4 Cluster, Jeffrey C. Boyington, Vadim Gladyshev, Sergei V. Khangulov, Thressa C. Stadtman, Peter D. Sun

Vadim Gladyshev Publications

Formate dehydrogenase H from Escherichia coli contains selenocysteine (SeCys), molybdenum, two molybdopterin guanine dinucleotide (MGD) cofactors, and an Fe₄S₄ cluster at the active site and catalyzes the two-electron oxidation of formate to carbon dioxide. The crystal structures of the oxidized [Mo( VI), Fe₄S_4(ox)] form of formate dehydrogenase H (with and without bound inhibitor) and the reduced [Mo(IV ), Fe₄S_4(red)] form have been determined, revealing a four-domain ab structure with the molybdenum directly coordinated to selenium and both MGD cofactors. These structures suggest a reaction mechanism that directly involves SeCys …

P53 Activation By Knockdown Technologies, Mara E. Robu, Jon D. Larson, Aidas Nasevicius, Soraya Beiraghi, Charles Brenner

Dartmouth Scholarship

Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to study gene function by sequence-specific knockdown. Both technologies, however, can elicit undesirable off-target effects. We have used several model genes to study these effects in detail in the zebrafish, Danio rerio. Using the zebrafish embryo as a template, correct and mistargeting effects are readily discernible through direct comparison of MO-injected animals with well-studied mutants. We show here indistinguishable off-targeting effects for both maternal and zygotic mRNAs and for both translational and splice-site targeting MOs. The major off-targeting effect is mediated through p53 activation, as detected …

Um Paleontologist Honored By Chinese University, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Electrophysiological And Morphological Heterogeneity Of Slow Firing Neurons In Medial Septal/Diagonal Band Complex As Revealed By Cluster Analysis, E. R. Garrido-Sanabria, M. G. Perez, C. Banuelos, T. Reyna, S. Hernandez, María Teresa Castañeda Licón, Luis V. Colom

Health & Biomedical Sciences Faculty Publications

Slow firing septal neurons modulate hippocampal and neocortical functions. Electrophysiologically, it is unclear whether slow firing neurons belong to a homogeneous neuronal population. To address this issue, whole-cell patch recordings and neuronal reconstructions were performed on rat brain slices containing the medial septum/diagonal band complex (MS/DB). Slow firing neurons were identified by their low firing rate at threshold (< 5Hz) and lack of time-dependent inward rectification (Ih). Unsupervised cluster analysis was used to investigate whether slow firing neurons could be further classified into different subtypes. The parameters used for the cluster analysis included latency for first spike, slow afterhyperpolarizing potential, maximal frequency and action potential (AP) decay slope. Neurons were grouped into three major subtypes. The majority of neurons (55%) were grouped as cluster I. Cluster II (17% of neurons) exhibited longer latency for generation of the first action potential (246.5±20.1 ms). Cluster III (28% of neurons) exhibited higher maximal firing frequency (25.3±1.7 Hz) when compared to cluster I (12.3±0.9 Hz) and cluster II (11.8±1.1 Hz) neurons. Additionally, cluster III neurons exhibited faster action potentials at suprathreshold. Interestingly, cluster II neurons were frequently located in the medial septum whereas neurons in cluster I and III appeared scattered throughout all MS/DB regions. Sholl’s analysis revealed a more complex dendritic arborization in cluster III neurons. Cluster I and II neurons exhibited characteristics of “true” slow firing neurons whereas cluster III neurons exhibited higher frequency firing patterns. Several neurons were labeled with a cholinergic marker, Cy3-conjugated 192 IgG (p75NTR), and cholinergic neurons were found to be distributed among the three clusters. Our findings indicate that slow firing medial septal neurons are heterogeneous and that soma location is an important determinant of their electrophysiological properties. Thus, slow firing neurons from different septal regions have distinct functional properties, most likely related to their diverse connectivity.

Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for May 24, 2007

Western News, May 24, 2007, Western Michigan University

Western News (1972-2018)

Story highlights: New office supports transfer students, veterans; Moser travels to Madagascar; Rubin receives Humboldt fellowship; On Campus with Michael Deblecourt.

Interview With Eddie Hill, O.T. Walter Professor Of Biology, Eddie Hill

Biology Department Oral Histories

No abstract provided.

Faculty Retirement Recognition Dinner 2007, Western Michigan University

Faculty Recognition

Faculty Retirement Recognition Dinner Program

May 24, 2007

Honored Guests:

• Michael B. Atkins
• Robert M. Beam
• Andrew A. Brogowicz
• William M. Cremin
• Ronald W. Davis
• Stuart J. Dybek
• Jorge M. Febles
• M. Arthur Garmon
• Marie F. Gates
• Thomas L. Gossman
• Philip J. Guichelaar
• Arlen R. Gullickson
• John M. Hanley
• Thomas R. Holmes
• Elaine A. Jayne
• Linda L. Law
• Charles Bruce MacQueen
• Bettina S. Meyer
• Daniel P. Mihalko
• Richard O'Hearn
• Paul E. Ponchillia
• Eldor C. Quandt
• Charlene Renner
• Visho Sharma
• Subhash R. Sonnad
• Judith F. Stone
• Charles Stroh
• Daniel L. Stufflebeam
• Paul E. Szarmach
• Larry J. ten Harmsel
• Thomas L. Van …

Pt-Ru Nanoparticles Supported On Carbon Nanotubes As Methanol Fuel Cell Catalysts, Liang Li, Yangchuan Xing

Chemical and Biochemical Engineering Faculty Research & Creative Works

Bimetallic Pt - Ru alloy catalysts have been demonstrated to be more active than pure Pt catalysts in the electrooxidation of methanol. We report here a study on Pt - Ru nanoparticle catalysts supported on sonochemically functionalized carbon nanotubes. the catalysts were prepared by directly reducing the corresponding salts, K2PtCl4 and K 2RuCl5, in an ethylene glycol aqueous solution containing dispersed carbon nanotubes. Three catalysts of different Pt to Ru atomic ratios, namely, Pt53Ru47, Pt69Ru31, and Pt77Ru23, were prepared for investigation of the compositional effects, It was shown that highly dispersed bimetallic Pt - Ru alloy nanoparticles with no agglomeration …

Daily Eastern News: May 24, 2007, Eastern Illinois University

May

No abstract provided.

Pedigree Tool, Madhumalar Panneerselvam

Theses

Collecting the family history to find the inheritance of trait is the fundamental concept in human genetics. The collected information on the family can be presented in an easily readable chart called Pedigree. Hand-drawn pedigrees become difficult when there is a large collection of known individuals in the family. Hence "Pedigree tool "was developed which automatically creates the Ancestor tree and Descendant tree. This tool also has an option to find the unrelated individuals. Inserting individual details into the database can also be done using this tool. Thus this user-friendly java based application can help researchers and genetic counselors to …

Lucrative Adoption Racket Threatened As U.S. And Guatemala Ratify Hague Convention, Mike Leffert

NotiCen

No abstract provided.