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2007

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Articles 13531 - 13560 of 14126

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The Relationship Of Risk For Unintentional Injury And Externalizing Behavior In Childhood., Elizabeth B. Bowling Jan 2007

The Relationship Of Risk For Unintentional Injury And Externalizing Behavior In Childhood., Elizabeth B. Bowling

All ETDs from UAB

No abstract provided.


Proteolysis And The Growth Hormone Receptor: Identification And Characterization Of Ghr As A Γ-Secretase Substrate, Jon Walter Cowan Jan 2007

Proteolysis And The Growth Hormone Receptor: Identification And Characterization Of Ghr As A Γ-Secretase Substrate, Jon Walter Cowan

All ETDs from UAB

No abstract provided.


An Evaluation Of Neighborhood Context And Health Lifestyles: Implications For Obesity Outcomes Among Children, Akilah Dulin Jan 2007

An Evaluation Of Neighborhood Context And Health Lifestyles: Implications For Obesity Outcomes Among Children, Akilah Dulin

All ETDs from UAB

No abstract provided.


Acute Effects Of Ambient Ozone On Daily Hospital Admissions And Daily Mortality For Respiratory And Cardiovascular Diseases Among Residents Of Bangkok, Thailand, Kannika Ruangdej Jan 2007

Acute Effects Of Ambient Ozone On Daily Hospital Admissions And Daily Mortality For Respiratory And Cardiovascular Diseases Among Residents Of Bangkok, Thailand, Kannika Ruangdej

All ETDs from UAB

No abstract provided.


Prepubertal Bisphenol A Exposure In The Rat Mammary Gland: Mechanism Of Action For Carcinogenesis, Nandini Raghuraman Jan 2007

Prepubertal Bisphenol A Exposure In The Rat Mammary Gland: Mechanism Of Action For Carcinogenesis, Nandini Raghuraman

All ETDs from UAB

No abstract provided.


Maternal Characteristics Associated With Language Outcomes Of Children Born At Less Than 32 Weeks Gestational Age, Richard V. Rector Jan 2007

Maternal Characteristics Associated With Language Outcomes Of Children Born At Less Than 32 Weeks Gestational Age, Richard V. Rector

All ETDs from UAB

No abstract provided.


Dysregulated Enac And Nhe Function In Cilium-Deficient Renal Collecting Duct Cell Monolayers, A Model Of Polycystic Kidney Disease, Dragos S. Olteanu Jan 2007

Dysregulated Enac And Nhe Function In Cilium-Deficient Renal Collecting Duct Cell Monolayers, A Model Of Polycystic Kidney Disease, Dragos S. Olteanu

All ETDs from UAB

No abstract provided.


Sturctural And Functional Analysis Of Klf4, Ashka Y. Pandya Jan 2007

Sturctural And Functional Analysis Of Klf4, Ashka Y. Pandya

All ETDs from UAB

No abstract provided.


Sunscreen Fluorescence In Skin, Skin Cells, And Dielectric Nanospheres: A New Method To Evaluate Sunscreen In A Novel Model System For Skin, Rajagopal Krishnan Jan 2007

Sunscreen Fluorescence In Skin, Skin Cells, And Dielectric Nanospheres: A New Method To Evaluate Sunscreen In A Novel Model System For Skin, Rajagopal Krishnan

All ETDs from UAB

No abstract provided.


Role Of Trip6 In Lpa-Induced Cell Migration, Yun-Ju Lai Jan 2007

Role Of Trip6 In Lpa-Induced Cell Migration, Yun-Ju Lai

All ETDs from UAB

No abstract provided.


Influence Of Cyp2c9 And Vkorc1 Genotypes On Warfarin Response In African-American And European American Patients, Nita A. Limdi Jan 2007

Influence Of Cyp2c9 And Vkorc1 Genotypes On Warfarin Response In African-American And European American Patients, Nita A. Limdi

All ETDs from UAB

No abstract provided.


Role Of Hypoxia In Epithelial Gene Regulation, Jennifer S. Guimbellot Jan 2007

Role Of Hypoxia In Epithelial Gene Regulation, Jennifer S. Guimbellot

All ETDs from UAB

No abstract provided.


Mechanisms Of P53-Mediated Apoptosis, Kelly Lynn Harms Jan 2007

Mechanisms Of P53-Mediated Apoptosis, Kelly Lynn Harms

All ETDs from UAB

No abstract provided.


Nitrite Conversion To Nitric Oxide: Biological Mechanisms And Therapeutic Implications, T Scott Isbell Jan 2007

Nitrite Conversion To Nitric Oxide: Biological Mechanisms And Therapeutic Implications, T Scott Isbell

All ETDs from UAB

No abstract provided.


Quantitative Magnetic Resonance: Validation Of The Echomri 3-In-1 Composition Analyzer, Angela S. Jones Jan 2007

Quantitative Magnetic Resonance: Validation Of The Echomri 3-In-1 Composition Analyzer, Angela S. Jones

All ETDs from UAB

No abstract provided.


Regulation Of Gene Expression In Response To Continuous Low Intensity Direct Current Electrical Fields, Jessica Amber Jennings Jan 2007

Regulation Of Gene Expression In Response To Continuous Low Intensity Direct Current Electrical Fields, Jessica Amber Jennings

All ETDs from UAB

No abstract provided.


Effects Of Pulsed Electromagnetic Stimulation On Cultured Dermal Fibroblasts From Diabetic And Non-Diabetic Rats, Cara Rouse Davis Jan 2007

Effects Of Pulsed Electromagnetic Stimulation On Cultured Dermal Fibroblasts From Diabetic And Non-Diabetic Rats, Cara Rouse Davis

All ETDs from UAB

Diabetes is a disease affecting an increasing number people each year. The medical costs of patients with diabetes are substantial due to the many complications associated with the disease. Dermal wounds are one of these complications and are often very difficult to properly heal. Pulsed Electromagnetic Fields (PEMFs) have been introduced as a method by which to speed the healing of dermal wounds. In this study, a device (provided by Biomet/EBI, Parsippany, NJ) for supplying PEMFs in vitro was used to stimulate dermal fibroblasts, one of the key cells in wound healing. These cells were isolated from the genetically diabetic …


Barrier Membranes For Ridge Augmentation - Is There An Optimal Pore Size?, Rajesh Gutta Jan 2007

Barrier Membranes For Ridge Augmentation - Is There An Optimal Pore Size?, Rajesh Gutta

All ETDs from UAB

Background: - Alveolar bone loss is often a sequelae of edentulism. However, several reconstruction procedures with bone grafts and barrier membranes are used to restore the lost bony architecture. The value of titanium mesh barriers has been shown to be reliable both in vertical and horizontal ridge augmentation procedures. However, there is a paucity of literature supporting the role of pore size of barrier membranes in preventing soft tissue ingrowth during ridge augmentation procedures. There are multiple reports describing a layer of soft tissue with varying thickness beneath the mesh and adhering to the newly regenerated bone. The objective of …


Metal-Tissue Interactions In Early Stage Biocorrosion Of Metallic Stents, Dina Halwani Jan 2007

Metal-Tissue Interactions In Early Stage Biocorrosion Of Metallic Stents, Dina Halwani

All ETDs from UAB

In-vivo corrosion of endovascular stents presents two main risks; release of toxic metallic ions and deterioration of the mechanical properties of the stents which may lead to fracture. Several studies have reported corrosion of nickel-titanium stent wires as well as stainless steel sternal wires. It has been suggested that when corrosion occurs on the surface of implants, an amount of metallic ions equivalent to the corroded volumes is released into surrounding tissue. The purpose of this study was to analyze explanted metallic stents for corrosion. The focus was on the detection of metallic ions released into surrounding vascular tissue as …


Acetylcholinesterase In The Sea Urchin Lytechinus Variegatus : Characterization And Developmental Expression In Larvae, Natalie A. Jennings Jan 2007

Acetylcholinesterase In The Sea Urchin Lytechinus Variegatus : Characterization And Developmental Expression In Larvae, Natalie A. Jennings

All ETDs from UAB

Acetylcholinesterase (AChE) in a deuterostome invertebrate, the echinoid Lytechinus variegatus, has been characterized. Kinetic parameters Vmax, Km, Kss, and b were 453 ± 183 μM ATCh hydrolyzed/minute, 185 ± 11 μM, 308 ± 100 mM, and 0.2, respectively for the substrate acetylthiocholine (ATCh) and 3.1 ± 1.2 μM BTCh hydrolyzed/minute, 654 ± 424 μM, 36 ± 31 mM, and 0.6, respectively for substrate butyrylthiocholine (BTCh). Pharmacologic analyses were performed with four inhibitors of cholinesterases, physostigmine, BW284c51, ethopropazine, and iso-OMPA, and yielded IC50 values of 106 ± 4 nM, 718 ± 118 nM, 2.57 ± 0.6 mM, and > 0.0300 M, respectively. …


Using Genetic Admixture And Lipo Protein Lipase Polymorphisms To Explain Variations In Plasma Triglycerides And High Density Lipoprotein Cholesterol In Premenopauasal African And European American Females, Nihal Omar Natour Jan 2007

Using Genetic Admixture And Lipo Protein Lipase Polymorphisms To Explain Variations In Plasma Triglycerides And High Density Lipoprotein Cholesterol In Premenopauasal African And European American Females, Nihal Omar Natour

All ETDs from UAB

Although African Americans (AA) are well known to be more obese and more in-sulin resistant than European Americas (EA), several studies have shown that AA have lower plasma triglyceride (TG) and higher high density lipoprotein cholesterol (HDL-C). The reasons for these levels of TG and HDL-C are not understood, and scientists have suggested a role of lipoprotein lipase (LPL), a key regulator of TG rich lipoproteins me-tabolism that is also thought to indirectly affect HDL-C metabolism. To investigate the extent to which these observed differences in TG and HDL-C are due to genetic makeup, we investigated the role of genetic …


In Vitro Compressive Fracture Resistance Of The Human Maxillary First Premolar With Different Mod Cavity Design And Restorative Materials, Wen-Chou Wu Jan 2007

In Vitro Compressive Fracture Resistance Of The Human Maxillary First Premolar With Different Mod Cavity Design And Restorative Materials, Wen-Chou Wu

All ETDs from UAB

Cuspal failures of MOD (mesial-occlusal-distal) restored teeth have been constantly observed in clinic especially those restored with amalgam. As the pulpal depth and isthmus width of the preparation increases, the strength decreases. A number of studies have investigated the adhesive technique which is intended to increase the fracture resistance by bonding the tooth structure. The results of the studies are controversial because of the differences of research design among studies. The purpose of this study is to evaluate the fracture resistance of the human maxillary first premolar restored with condensable composite (Surefil, Dentsply) and CEREC 3D ProCAD leucite-reinforced ceramic inlays …


Depressive Symptomatology And Suicide Attempts In Adolescents With Mobility Limitations, Ann I. Alriksson-Schmidt Jan 2007

Depressive Symptomatology And Suicide Attempts In Adolescents With Mobility Limitations, Ann I. Alriksson-Schmidt

All ETDs from UAB

Adolescents with mobility limitations may be at increased risk of certain adverse outcomes because of unique or exacerbated pre-existing challenges. The current study examined the relationships among mobility limitations, depressive symptomatology, and suicidal behaviors. Moreover, it was examined if pain and perceived social support mod-erated the relationships between severity of mobility limitations and the three outcome variables, and whether depressive symptomatology mediated the relationships between mobility limitations and suicidal behaviors. Secondary analyses of the AddHealth data set were performed. The sample was 49.18% female, 16.02% African-American, 65.46% Caucasian, 12.20% Hispanic, and 6.33% coded as Other. The mean age was 15.96 …


The Role Of Cd5 In Experimental Autoimmune Encephalitomyelitis, Robert C. Axtell Jan 2007

The Role Of Cd5 In Experimental Autoimmune Encephalitomyelitis, Robert C. Axtell

All ETDs from UAB

The regulation of activation, differentiation and persistence of effector T-cells are critical for the development of Experimental Autoimmune Encephalomyelitis (EAE), the animal model of Multiple Sclerosis. Until now, the function of CD5 was accepted to be a negative regulator of T-cell activation. This dissertation reports that CD5 has an addi-tional role in T-cell responses, which is to promote cell survival. Observations from EAE experiments revealed that mice deficient in CD5 exhibited decreased disease severity which was associated with the inability of activated T-cells to survive. Moreover, block-ing the engagement of CD5 in mice led to enhanced activation induced cell death …


Cd8+ T-Lymphocytes And The Control Of Cytomegalovirus Infection Of The Newborn Central Nervous System, Glenn Robert Burgner Bantug Jan 2007

Cd8+ T-Lymphocytes And The Control Of Cytomegalovirus Infection Of The Newborn Central Nervous System, Glenn Robert Burgner Bantug

All ETDs from UAB

Congenital HCMV infection of the developing brain is the leading viral cause of mental retardation and sensorineural hearing loss. To elucidate the pathogenesis of congenital HCMV CNS infections, we developed a small animal model of CMV infection where newborn Balb/c mice are peripherally inoculated with murine cytomegalovirus. In this model we observed transient deficits in cerebellar/hindbrain development as well as the recruitment of peripheral immune effector cells to the CNS parenchyma. CD8+ T-lymphocytes were the predominant mononuclear cellular infiltrates in the brain and immune-depletion of CD8+ cells resulted in increased viral genome copy numbers in the CNS. CD8+ T-lymphocytes exhibited …


Green Tea Polyphenols Are Associated With Changes In Genetic And Epigenetic Anti-Cancer Mechanisms In Vitro And In Vivo, Joel Bradford Berletch Jan 2007

Green Tea Polyphenols Are Associated With Changes In Genetic And Epigenetic Anti-Cancer Mechanisms In Vitro And In Vivo, Joel Bradford Berletch

All ETDs from UAB

Human chromosomes are protected from degradation associated with cell division by hexameric repeats of 5’-TTAGGG-3’ termed telomeres. During cellular replication human chromosomes undergo the loss of up to 300 bp of DNA with each division, reaching a critical length which leads to senescence and apoptosis. Most cancer cells bypass this lifespan regulatory mechanism by the expression of telomerase, a protein complex that adds telomeres through the reverse transcriptase activity of its catalytic subunit, hTERT. Approximatly 90% of all cancers express the hTERT gene making it an attractive target for novel cancer therapies. The objective of this dissertation was to help …


Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta Jan 2007

Impact Of Immunosuppression On The Incidence And Clearance Of Human Papillomavirus In Hiv-Infected Women In Alabama, Madhav P. Bhatta

All ETDs from UAB

Persistent infection with certain “high-risk” types of human papillomavirus (HPV) infection is central to the development of cervical cancer. Human immunodeficiency virus (HIV)-infected women are at a higher risk of HPV infection, high grade cervical intraepithelial lesions, and cervical cancer. This study examined type-specific distribution of prevalent and incident HPV infections, clearance rates, and associated factors using novel molecular assays for HPV detection and genotyping in a cohort of 280 HIVinfected women in Alabama. First, we described the cohort’s sociodemographic characteristics and behavioral risk profile for HIV and other sexually transmitted infections, and assessed the factors associated with HIV-1 viral …


Understanding The Local Livelihood System In Resource Management: The Pelagic Longline Fishery In Gouyave, Grenada, Sandra C. Grant, Fikret Berkes, John Brierley Jan 2007

Understanding The Local Livelihood System In Resource Management: The Pelagic Longline Fishery In Gouyave, Grenada, Sandra C. Grant, Fikret Berkes, John Brierley

Gulf and Caribbean Research

There is a need to include social objectives in fisheries management, and this paper focuses on one set of social considerations, those regarding livelihood. We pay particular attention to sustainable livelihood strategies, the importance of commercial pelagic longline fishing for the entire community livelihood system, and implications for management. Field data were obtained between December 2002 and March 2004 in Gouyave, Grenada, using participant observation, semi-structured interviews, and a quantitative survey. The economic base (fishing and agriculture) of the community is both unpredictable and seasonal, therefore individuals and households engage in diverse strategies to secure their livelihood. Three livelihood strategies …


Whale Sharks Of The Western Caribbean: An Overview Of Current Research And Conservation Efforts And Future Needs For Effective Management Of The Species, Rachel T. Graham Jan 2007

Whale Sharks Of The Western Caribbean: An Overview Of Current Research And Conservation Efforts And Future Needs For Effective Management Of The Species, Rachel T. Graham

Gulf and Caribbean Research

Whale sharks (Rhincodon typus) are seasonal visitors to four sites in the Western Caribbean, 3 of which are encompassed by the Mesoamerican Barrier Reef. Predictable encounters with the world's largest fish have raised this species' profile globally and led to several research and conservation efforts that aim to elucidate the need for information for the species management and balance the growing demand for highly lucrative encounter tourism. Tagging studies have demonstrated that the whale shark population is relatively small and likely forms a single population. Individuals move throughout the region between 3 of 4 known feeding sites and …


Good Things Come In Small Packages: Tiny Plankton Producing Oxygen Near Dead Zone, Abbie Basile Jan 2007

Good Things Come In Small Packages: Tiny Plankton Producing Oxygen Near Dead Zone, Abbie Basile

Libraries Faculty & Staff Publications

(First paragraph) For many, the words “Lake Erie” bring to mind large things: big sport fish, sprawling waterfront homes, and an enormous body of water bordering four states and two countries. Similarly, much of the Lake Erie research of which the public is aware deals with larger biological organisms—larger algae and zooplankton, the small fish that eat the zooplankton, and the large fish that feed on those smaller fish. Over the years, the smaller lake life have been somewhat overlooked.