Digital Commons Network^™

Type 1 Pili Mediated Bacterial Adherence To The Canine Bladder, Darcie A. Ohlman

Graduate Theses and Dissertations

No abstract provided.

Human Interaction As Manifested Through The Body: The Socially Experienced Self And The Dialogical Construction Of Eating Disorders, Laura Dawn Russell

Graduate Theses and Dissertations

No abstract provided.

Characteristics Of Ohio Schools With Adequate Yearly Progress For Students With Disabilities, Patricia Ellis Hoyle

Graduate Theses and Dissertations

No abstract provided.

The Relationship Among Stress, Support, Depression, And Academic Performance For Rural Adolescents, Sandra Ann Hartings

Graduate Theses and Dissertations

The constructs of stress, support, depression, and academic performance have been mostly addressed on an individual basis. Stress research with children and adolescents has not been as rigorous as research with adults. There are also a number of gaps in the research literature related to support. The decrease in age of the first onset of depressive episodes, along with the high prevalence of depression in adolescence, emphasizes the need to expand research in this area. Also, few studies have attempted to identify interpersonal variables that may serve as antecedents of school achievement. The purpose of this study was to examine …

Opportunities For Undergraduate Research Experiences (Oure) Research Papers 2006-2007 Vol. I, Ryan Abington, Sunil Aggarwal, Emily Bahram-Ahi, Lia Raquel Otal Bartnicki, Navarre Bartnz, Matthew Beyer, Devin Boyle, Joshua Bunch, Adam Bunton, Joshua Cardenzana, Joshua Carey, Brandi Clark, Cary Cooper, Ryan Dusheke, Agatha Dwilewicz, Joshua Eads, Josiah Elliott, Justin Enderle, David Erdos, Tyler Fears, Nathaniel Goss

Opportunities for Undergraduate Research Experience Program (OURE)

No abstract provided.

Growth Of Mc3t3-El Pre-Osteoblasts On Borate Containing Glasses & Growth Of Osteoblastic Cells On 13-93 Glass Scaffolds, Agatha Dwilewicz

Opportunities for Undergraduate Research Experience Program (OURE)

Three borate-based glasses, compositions designated 1B, 2B, and 3B, with B₂0₃ levels of 15, 31, and 46 mole percent (Table 1), respectively, were tested for their effects on the growth of MC3T3-El mouse pre-osteoblastic cells under physiological fluid conditions. Silicate type 45S5 glass was used as a control for comparison. Independently, the biocompatibility of recently developed silicate-based porous 13-93 bioactive glass scaffolds was tested; Saos-2 human osteosarcoma cell line was used. Tests performed for the two studies included: contact assays of cell growth at the glass interface, chemical analysis of borate released into the culture medium, quantitative …

A Broad Perspective On Current And Future Research On Urban Coyotes, John A. Shivik, Kathleen Fagerstone

United States Department of Agriculture Wildlife Services: Staff Publications

A change in wildlife management appears to be occurring. Previous efforts needed to be focused on producing more game species or endangered animals; now, however, tools and training must resolve issues of overabundance and conflict with predators, especially species such as coyotes (Canis latrans) in urban areas. Urban conflicts with coyotes may be growing because of urban development of land and human intrusion, but alteration of habitats that attract coyotes is also a likely factor. Research that will describe basic coyote biology in urban areas will be needed, but managers will also need applied research and development of …

Dna: Modeling Structure And Function, Jennifer A. R. Smith, Cynthia J. Martin

Iowa Science Teachers Journal

This article presents a developmentally appropriate approach to introduce high school biology students to the structure of DNA and illustrate how its structure and function are related. We address the importance of beginning instruction with a concrete representation of DNA, and using it to scaffold to several important biological concepts. We also make clear the teacher's crucial role in this scaffolding process. This article promotes National Science Education Content Standards C and G, and Iowa Teaching Standards 1, 2, 3, 4, and 7.

When Molecular Worlds Collide: Developing The Conceptual Groundwork Needed To Understand Molecular Motion, Scott M. Moore Jr., Kara Victorsen

Iowa Science Teachers Journal

The activity described in this article introduces students to the concept of molecular motion and how it is affected by temperature using two simple ingredients: water and food coloring. In the hands of a highly effective science teacher, this activity will promote student inquiry, creative and critical thinking, effective communication, and cooperative learning. This activity is appropriate for use in both physical science and chemistry. The activity described here promotes National Science Education Content Standards A, B, and G, and Iowa Teaching Standards 1, 2, 3, and 5.

Synergistic Relationships: Why Effective Teaching Is Complex, Michael P. Clough

Iowa Science Teachers Journal

The crucial role of teachers in creating powerful learning environments has been a consistent feature of editorials and articles appearing in ISTJ under my editorship. Research makes clear that what teachers do significantly impacts their students' achievement, interest in a field of study, and attitude toward schooling in general. The cognitive and affective climate of classrooms is influenced by the learning and behavioral expectations set by teachers, the activities and instructional strategies they choose, the behaviors they exhibit when interacting with students, and many other important teacher decisions.

How Are We Stacking Up?: Current Reforms In Science Education Twelve Years After Publication Of The National Science Education Standards, Robert E. Yager

Iowa Science Teachers Journal

In education Science-Technology-Society (STS) is commonly viewed as another add-on to a course or the curriculum. This view portrays STS as being plagued with the same problems as traditional teaching of science and technology; information is transmitted to students by lecture, verification laboratories, or textbooks and other written materials. This article presents the case that STS instruction, when effectively implemented, captures more broadly key aspects of both science and technology, and does not succumb to the common problems of traditional instruction. Essential characteristics of effective science teaching are presented.

The Big One, Edward A. Parson

Reviews

Richard Posner's Catastrophe: Risk and Response (Oxford University Press, 2004) examines four risks whose worst cases could end advanced human civilization or worse: asteroid impacts, a catastrophic chain reaction initiated in high-energy particle accelerators, global climate change, and bioterrorism. He argues that these all warrant more thought and response than they are receiving, and that they can usefully be assessed using a simple analytic framework based on cost-benefit analysis. This essay reviews knowledge of these risks and critically examines Posner's claims for a consistent analytic approach. While the conclusions that each risk merits more thought and effort appear persuasive, these …

The Role Of The Fda In Innovation Policy, Rebecca S. Eisenberg

Michigan Telecommunications & Technology Law Review

This Article reexamines the role of FDA regulation in motivating investment in biopharmaceutical innovation. I begin by challenging the standard story that it is the patent system that makes drug development profitable, and drug regulation that makes it costly, by showing how patents add to costs and how drug regulation works in tandem with patents to protect profits. I then compare FDA-administered exclusive rights to patents as a means of fortifying drug development incentives, suggesting ways that FDA-administered rights might be preferable both from the perspective of policy makers and from the perspective of firms. In the remainder of the …

Diversifying Without Discriminating: Complying With The Mandates Of The Trips Agreement, Graeme B. Dinwoodie, Rochelle C. Dreyfuss

Michigan Telecommunications & Technology Law Review

Since the Patent Act was revised in 1952, patent law has expanded to cover an array of novel endeavors--new fields of technology (notably computer science and business methods) as well as the activities of researchers engaged in fundamental scientific discovery. These changes have been accompanied by shifts in the organizational structure of the technological community, with smaller firms and universities emerging as important players in the patent system, and by new marketplace expectations arising from consumer demand for interoperable technology and converging functionality. As a result of these developments, structural flaws in the legal order have become evident. Although the …

Restoring The Genetic Commons: A Common Sense Approach To Biotechnology Patents In The Wake Of Ksr V. Teleflex , Anna Bartow Laakmann

Michigan Telecommunications & Technology Law Review

In this Article, I argue that a new approach to biotechnology patenting is necessary to fully realize the tremendous potential of recent advances in our understanding of the human genome. Part I places the gene patenting debate in context by highlighting the key landmarks that have shaped the biotechnology industry and outlining the products and stakeholders that comprise the industry. Part II describes the current state of the law on biotechnology patents, summarizing the Federal Circuit's application of the various doctrines that collectively define the patent landscape's parameters. In this Part, I explain how the Federal Circuit's jurisprudence is tied …

The Patent End Game: Evaluating Generic Entry Into A Blockbuster Pharmaceutical Market In The Absence Of Fda Incentives, Jeremiah Helm

Michigan Telecommunications & Technology Law Review

Generic drugs play an important role in the American system of health care. Most anticipate that the entry of these drugs into the market will lower prices and thereby increase treatment options for consumers. To stimulate generic entry, the Food and Drug Administration currently offers a period of marketing exclusivity to the first firm that gains approval for a generic version of a branded drug. During this 180-day period, only two firms can sell versions of the drug: the original, branded drug maker and the first approved generic firm. After the period of exclusivity expires, other generic firms are free …

Fda Approval Of Generic Biologics: Finding A Regulatory Pathway, Kathleen R. Kelleher

Michigan Telecommunications & Technology Law Review

Biologics are becoming increasingly important for the potential treatment of widespread diseases such as cancer, anemia, and diabetes. As hundreds of biologics are going off-patent, the market has become ripe for the introduction of generic biologics. A regulatory pathway for biogenerics, however, is virtually nonexistent. The purpose of this paper is thus to analyze how a successful legislative pathway for generic biologics might be designed. The current regulatory scheme, economic concerns, health and safety concerns, and the need to provide proper incentives for innovation are analyzed. Finally, recent Congressional bills are outlined and critiqued, through which the structure of a …

Front Matter

Michigan Telecommunications & Technology Law Review

No abstract provided.

Uab Magazine - Fall 2007, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

Recovery In A Cynical Time - With Apologies To Eric Arthur Blair, Dale Goble

Articles

No abstract provided.

The Use Of Drug Testing To Police Sex And Gender In The Olympic Games, Haley K. Olsen-Acre

Michigan Journal of Gender & Law

Part I of this Article discusses the history and development of sex testing and drug testing and argues that the two are both historically and ideologically linked. Part II examines the current Code in detail and argues that the Code's focus on hormone-based controls acts to police sex and gender in Olympic athletes, thereby extending historical sex testing practices to a new era. This Article ultimately concludes that without recognizing and addressing the need for further research into the role of "sex" hormones in the body and the interplay of social context and biological circumstances, the IOC cannot maintain an …

Compensation For Porperty Under The European Convention On Human Rights, Tom Allen

Michigan Journal of International Law

This Article asks whether the right to property, as a human right, serves the same general purpose as other human rights. The Article does so by examining the standards relating to compensation for deprivations of property under the European human rights system. If the system protects property for similar reasons as other fundamental rights, the interpretation of the right to property should draw upon the principles developed in relation to the interpretation of other rights. However, if the right to property is distinct from other human rights, then perhaps guidance on its interpretation should come from comparative law, specifically in …

Relationships, Income Support And Decision Making: A Qualitative Synopsis, Angie Logan, Kevin Meir

Journal of Family Strengths

This qualitative study of one midwestern state’s child protective services addresses whether an income support measure for poor biological caregivers reduces the length of time that their children spend in foster care. The overall findings suggest that workers do value the worker-family relationship. However, some view the immediate worker-client relationship as secondary to the inclusion of extended familial supports particularly as related to sustained more long-term outcome achievement. Most workers additionally agree that client involvement during all phases of the reunification process is critical.

Lida: A Computational Model Of Global Workspace Theory And Developmental Learning, S. Franklin, U. Ramamurthy, S. Mello, L. Mccauley, A. Negatu, R. Silva, V. Datla

CCRG Papers

No abstract provided.

Standing Closest To The Flame: Community Wildfire Planning And The Healthy Forest Act, William E. Fleeger

Doctoral Dissertations

Recently, national fire policy has been redirected from a primary focus on suppression towards a more integrated and comprehensive approach developed at the community level. As part of this policy shift, Congress passed the Healthy Forest Restoration Act (P.L. 108-148) in 2003 encouraging communities to develop community wildfire protection plans (CWPPs) to guide fuel reduction and wildfire mitigation efforts on both federal and nonfederal lands. This research examines U.S. Forest Service (USFS) and community collaboration in the development of CWPPs through a case study analysis of four communities in two western states. The social and decision-making processes used in the …

Parental Emotion Coaching: How Does It Relate To Attachment, Anger, Assertiveness, And Conflict Management?, Ines S. Cofrin

Doctoral Dissertations

This study investigated the relationship between participants' retrospective reports of parental emotion coaching (EC) and emotion dismissing (ED) and participants' anger, romantic attachment, assertiveness, and conflict management. EC and ED were assessed by a retrospective self-report developed by the author (RECS; Kroll, 2002), based on Gottman's theory (Gottman, Katz, & Hooven, 1996). Results suggested that for most analyses, EC and ED correlated significantly with all outcome variables, even after controlling for attachment and caregiver emotional stability. Retrospective EC and ED were also assessed directly from primary caregivers through a mailed survey, and correlated with participants' reports of EC and ED. …

Resolving The 150 Year Debate Over The Ecological History Of The Common Periwinkle Snail, Littorina Littorea, In Northeast North America, April M H Blakeslee

Doctoral Dissertations

Littorina littorea (common periwinkle snail) is highly abundant in both Europe and North America. A known native of Europe, its presence in North America has been the subject of a one-hundred year debate. Prior published work attempting to resolve its cryptogenic (=uncertain origin) status with historical, archaeological, ecological and/or genetic data were not successful. I therefore included novel parasite and molecular evidence to definitively resolve L. littorea's North American cryptogenic status.

First, I explored trematode species richness patterns in European versus North American L. littorea and two co-occurring native congeners, L. saxatilis and L. obtusata. Through extensive field and literature …

Interactions Between Two Invasive Crab Predators, Carcinus Maenas And Hemigrapsus Sanguineus, And Consequences For The Native Community, Blaine David Griffen

Doctoral Dissertations

With continued globalization, species are being transported and introduced into novel habitats at an accelerating rate. As invasive species become more common, interactions between invasive species will also increase and may alter the way that these species impact invaded communities. The European green crab Carcinus maenas is an aggressive predator that was introduced to the east coast of North America in the mid 1800s and often has detrimental impacts on prey communities. A newer invasive predator, the Asian shore crab Hemigrapsus sanguineus, was first discovered on the Atlantic coast in the 1980s, and now inhabits many of the same regions …

Valence And Structure Relationships In Oligonucleotides, Carrie Ann May

Doctoral Dissertations

There are many models that can be used to estimate the degree of shielding and predict the valence of a nucleic acid. Here, Counter-ion Condensation theory and Grand Canonical Monte Carlo simulations are compared with an experimental approach. Membrane-Confined Electrophoresis was used to measure the effective valence of several nucleic acid oligomers. The Debye-Huckel-Henry equation was then utilized to calculate the valence of these oligomers. The valence was determined to be -17.86 (+/- 1.03) for a 20 base-pair double-stranded DNA oligomer in 93 mM KCl and 10 mM Tris HCl, pH 8. This experimental value agrees well with rigorous Grand …

Fullerene-Acene Chemistry: Part I Studies On The Regioselective Reduction Of Acenes And Acene Quinones; Part Ii Progress Toward The Synthesis Of Large Acenes And Their Diels-Alder Chemistry With [60]Fullerene, Andreas John Athans

Doctoral Dissertations

The regioselective reduction of acenes and acene quinones has been studied. Using hydriodic acid (HI) in acetic acid (HOAc) as reductant, it was found that acenes smaller than five rings reduce in a regioselective fashion. It was also found that phenyl substituted acenes with as many as seven rings will reduce regioselectively to leave the internal terphenyl moieties intact. In the cases of 6,13-diphenylpentacene and 5,7,12,14-tetraphenylheptacene quinone, reduction occurs at alternating rings such that the end rings and the internal terphenyl moieties were left intact. When large unsubstituted acenes are reduced, the reduction occurs with no selectivity resulting in complex …