Digital Commons Network^™

Marine Proteomics, Bl Nunn, At Timperman

Faculty & Staff Scholarship

No abstract provided.

Testing Drugs Versus Testing For Drug Use: Private Risk Management In The Shadow Of Criminal Law, Robert J. Maccoun

DePaul Law Review

No abstract provided.

High-Resolution Vascular Imaging Of The Rat Spine Using Liposomal Blood Pool Mr Agent, K B Ghaghada, K H J Bockhorst, S Mukundan, A V Annapragada, P A Narayana

Faculty, Staff and Student Publications

BACKGROUND AND PURPOSE: High-resolution, vascular MR imaging of the spine region in small animals poses several challenges. The small anatomic features, extravascular diffusion, and low signal-to-noise ratio limit the use of conventional contrast agents. We hypothesize that a long-circulating, intravascular liposomal-encapsulated MR contrast agent (liposomal-Gd) would facilitate visualization of small anatomic features of the perispinal vasculature not visible with conventional contrast agent (gadolinium-diethylene-triaminepentaacetic acid [Gd-DTPA]). METHODS: In this study, high-resolution MR angiography of the spine region was performed in a rat model using a liposomal-Gd, which is known to remain within the blood pool for an extended period. The imaging …

Predictive Oncology: A Review Of Multidisciplinary, Multiscale In Silico Modeling Linking Phenotype, Morphology And Growth, Sandeep Sanga, Hermann B. Frieboes, Xiaoming Zheng, Robert Gatenby, Elaine L. Bearer, Vittorio Cristini

Faculty, Staff and Student Publications

Empirical evidence and theoretical studies suggest that the phenotype, i.e., cellular- and molecular-scale dynamics, including proliferation rate and adhesiveness due to microenvironmental factors and gene expression that govern tumor growth and invasiveness, also determine gross tumor-scale morphology. It has been difficult to quantify the relative effect of these links on disease progression and prognosis using conventional clinical and experimental methods and observables. As a result, successful individualized treatment of highly malignant and invasive cancers, such as glioblastoma, via surgical resection and chemotherapy cannot be offered and outcomes are generally poor. What is needed is a deterministic, quantifiable method to enable …

Computer Simulation Of Glioma Growth And Morphology, Hermann B. Frieboes, John S Lowengrub, S Wise, X Zheng, Paul Macklin, Elaine L. Bearer, Vittorio Cristini

Faculty, Staff and Student Publications

Despite major advances in the study of glioma, the quantitative links between intra-tumor molecular/cellular properties, clinically observable properties such as morphology, and critical tumor behaviors such as growth and invasiveness remain unclear, hampering more effective coupling of tumor physical characteristics with implications for prognosis and therapy. Although molecular biology, histopathology, and radiological imaging are employed in this endeavor, studies are severely challenged by the multitude of different physical scales involved in tumor growth, i.e., from molecular nanoscale to cell microscale and finally to tissue centimeter scale. Consequently, it is often difficult to determine the underlying dynamics across dimensions. New techniques …

Grand Canyon Reveals Nautiloid Mass Kill Event (Faith & Science Update), John T. Baldwin

Perspective Digest

No abstract provided.

Academic Writing And Theological Inquiry, Terry Dwain Robertson

Faculty Publications

A comparison of two approaches to academic writing and research pedagogies demonstrates that, for Vyhmeister, truth is to be found outside and above us--it is a process of discovery, while Hamilton's approach focuses on the spiritual formation of the writer and can be understood as reflecting a process of spiritual growth. A third approach, which I develop in this article, views academic writing and theological inquiry as a ministry, in which the writer is served by and, in turn, serves the community of faith for the purpose of building a corporate knowledge of God. Research is service and the dissemination …

The Effect Of Gm Label Variation On Perceptions Of Genetically Modified Foods, Alexandra Jane Costello

School of Psychology Theses

This thesis investigates the factors which are suggested to affect perceptions of genetically modified (GM) foods. It first tests the extent to which the components of the Theory of Planned Behaviour and perceived `outrage' are able to predict intentions towards buying GM foods using linear regression. It then focuses on how GM label design characteristics and linguistic variations influence perceptions of GM foods including measures of hazard perception and purchase intention using ANOVA repeated measures. Modelling is then used to identify whether label variations affect the components of the Theory of Planned Behaviour, namely attitudes, subjective norms and perceived behavioural …

Enhanced Fire Retardancy Of Vinyl Ester Resins By Combination Of Additives, Grace Chigwada, Charles A. Wilkie

Chemistry Faculty Research and Publications

In pursuit of fire-retardant materials, vinyl ester resins were combined with commercially available fire retardants at lower loadings than that at which they are usually effective when used alone. The thermal stability and flammability of the various combinations of fire retardants were evaluated by thermogravimetric analysis and cone calorimetric analysis. With some combinations, the 50% degradation temperature was improved by about 5-10ºC Different additives affected the flammability to varying extents and some combinations resulted in an enhanced fire retardancy compared to the additives used alone. The combinations that showed the best reductions in the peak heat release rate (PHRR) were …

Evolution Of Symbiotic Bacteria In The Distal Human Intestine, Jian Xu, Michael A. Mahowald, Ruth E. Lay, Catherine A. Lozupone, Micah Hamady, Eric C. Martens, Bernard Henrissat, Pedro M. Coutinho, Patrick Minx, Philippe Latreille, Holland Cordum, Andrew Van Brunt, Kyung Kim, Robert S. Fulton, Lucinda A. Fulton, Sandra W. Clifton, Richard K. Wilson, Robin D. Knight, Jeffrey I. Gordon

Open Access Publications

No abstract provided.

Psychometric Properties Of Dsm Assessments Of Illicit Drug Abuse And Dependence: Results From The National Epidemiologic Survey On Alcohol And Related Conditions (Nesarc), M. T. Lynskey, A. Agrawal

Open Access Publications

No abstract provided.

A Gambling Paradox: Why An Origin-Neutral 'Zero-Quota' Is Not A Quota Under Gats Article Xvi, Donald H. Regan

Articles

In US-Gambling, the Appellate Body held that an origin-neutral prohibition on remote gambling (which is how they mostly viewed the United States law) was "in effect" a "zero-quota", and that such a "zero-quota" violated GATS Article XVI:2. That holding has been widely criticized, especially for what critics refer to as the Appellate Body's "effects test". This article argues that the Appellate Body's "in effect" analysis is not an "effects test" and is not the real problem. The real mistake is regarding a so-called "zero-quota" as a quota under Article XVI. That is inconsistent with the ordinary meaning of the word …

State Of Utah, By And Through Its Engineering Commission, D. H. Whittenburg, Chariman, H. J. Corleissen And Layton Maxfield, Members Of The Engineering Commission V. Burton F. Peek And Charles D. Wiman, Trustees Under The Will And Of The Estate Of Charles H. Deere, Deceased : Brief Of Appellant, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

APPELLANTS' BRIEF.

State Of Utah V. Ronald Richard Rodrigues : Brief Of Appellant, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

Appeal from Amended Restitution Order entered after judgment on August 15, 2007. the Honorable Robin Reese, Judge, Third District Court, Salt Lake County. State of Utah, presiding.

State Of Utah V. Ronald Richard Rodrigues : Brief Of Respondent, Utah Supreme Court

Utah Supreme Court Briefs (2000–2020)

Supplemental Brief of Respondent Appeal from an amended restitution order following a guilty plea to criminal nonsupport, in the Third Judicial District Court of Utah, Salt Lake County, the Honorable Robin W. Reese presiding.

Book Review: No Place To Hide, Gary C. Kessler

Publications

This document is Dr. Kessler's review of No Place to Hide, by Robert O'Harrow, Jr. Free Press, 2006. ISBN 0-7432-8705-3.

Multiphoton Response Of Retinal Rod Photoreceptors, Vasilios Alexiades, Harihar Khanal

Publications

Phototransduction is the process by which light is converted into an electrical response in retinal photoreceptors. Rod photoreceptors contain a stack of (about 1000) disc membranes packed with photopigment rhodopsin molecules, which absorb the photons. We present computational experiments which show the profound effect on the response of the distances (how many discs apart) photons happen to be absorbed at. This photon-distribution effect alone can account for much of the observed variability in response.

Permanent Establishment In The Digital Age: Improving And Stimulating Debate Through An Access To Markets Proxy Approach, Benjamin Hoffart

Northwestern Journal of Technology and Intellectual Property

No abstract provided.

Well Duh: Obviousness, Gas Pedals, And The Teaching-Suggestion-Motivation Test, Randall J. Hirsch , M.D.

Northwestern Journal of Technology and Intellectual Property

No abstract provided.

Global Intellectual Property Rights And Economic Growth, Linda Y. Yueh

Northwestern Journal of Technology and Intellectual Property

This article argues that the global intellectual property rights regime will affect the economic growth prospects of developing countries. The trade-related aspects of intellectual property rights (TRIPS) provisions under the WTO articles will eventually cover all of its member countries, currently at around 150 and representing 95% of world trade. It is a significant change in the global legal system with implications for economic growth. One of the key mechanisms generating convergence in global economic growth rates is the transfer of technology from developed to developing countries. According to the neoclassical models of growth, technology is embodied within the capital …

Law And Economics After Behavioral Economics, Grant M. Hayden, Stephen E. Ellis

Hofstra Law Faculty Scholarship

This paper assesses the current state of law and economics, standard and behavioral, and proposes an additional element to the basic belief-desire apparatus of economic theory in order to create a more unified theory of behavior.

The first part of the paper assesses the current status of standard economic theory. While standard models have had their successes, a large and growing body of empirical evidence reveals that people often fail to live up its rational-actor ideal. In response, economists usually stick with standard consumer theory and attempt to explain the anomalous results by referring to some overlooked input (e.g., some …

Relationships Between Body Size And Abundance In Ecology, Ethan P. White, S.K. Morgan Ernest, A. J. Kerkoff, B. J. Enquist

Biology Faculty Publications

Body size is perhaps the most fundamental property of an organism and is related to many biological traits, including abundance. The relationship between abundance and body size has received much attention, both to quantify the form of the relationship and to understand the processes that generate it. However, progress is impeded by the underappreciated fact that there are four distinct, but inter-related, relationships between size and abundance that are often confused in the literature. Here, we review and distinguish between these four patterns, and discuss the linkages between them. We argue that a synthetic understanding of size and abundance relationships …

Challenges In The Application Of Geometric Constraint Models, C. R. Mcclain, Ethan P. White, A. H. Hurlbert

Biology Faculty Publications

Discerning the processes influencing geographic patterns of species richness remains one of the central goals of modern ecology. Traditional approaches to exploring these patterns have focused on environmental and ecological correlates of observed species richness. Recently, some have suggested these approaches suffered from the lack of an appropriate null model that accounts for species’ ranges being constrained to occur within a bounded domain. Proponents of these null geometric constraint models (GCMs), and the mid-domain effect these models produce, argue their utility in identifying meaningful gradients in species richness. This idea has generated substantial debate. Here we discuss what we believe …

The Irrelevance, And Central Relevance, Of The Boundary Between Science And Non-Science In The Evaluation Of Expert Witness Reliability, D. Michael Risinger

Villanova Law Review (1956 - )

No abstract provided.

Motives For Idealizing The Pragmatic, Lewis H. Larue

Villanova Law Review (1956 - )

No abstract provided.

The Molecular Biology Of Temperature-Dependent Sex Determination In Reptiles, Keela Dodd

All ETDs from UAB

Temperature-dependent sex determination (TSD) is a type of environmental sex determination in which the egg’s incubation temperature determines the sex of the embryo. The exact physiology of TSD is not yet understood. Hormones and temperaturetriggered genes have been hypothesized to play a role. This study evaluates putative male and female factors that may play a role in TSD. Regarding female factors, this study evaluates clutch sensitivity to estradiol-17β and an aromatase inhibitor, and estradiol- 17β’s potential role in müllerian duct differentiation. Regarding male factors, this study also quantifies SOX9 mRNA during TSD in untreated and estradiol-17β treated embryos. In the …

Pneumococcal Choline-Binding Protein A: Its Role In Virulence And Its Utility As A Streptococcus Pneumoniae Vaccine Antigen, David Tawayne Glover

All ETDs from UAB

Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. S. pneumoniae is a leading cause of pneumonia, meningitis, septicemia, and otitis media. Although all age groups can be affected, children and the elderly are espccially susceptible to infection. Currently there is a conjugate vaccine available for use, but this vaccine only contains capsular polysaccahride antigens from the seven most prevelant S. pneumoniae serotypes. The use of the conjugate vaccine has led to serotype shift, with more disease being caused by non-vaccine serotype bacteria. The studies presented in this dissertation identify and characterize a novel S. penumoniae vaccine candidate …

On The Dynamical, Geometric, And Arithmetic Properties Of Euclidean Lattices, Lee Michael Goswick

All ETDs from UAB

This dissertation consists of three papers concerning certain aspects of Euclidean lattices. The first two examine dynamical properties of 2D billiards in the lattices Z2 and Z2 ∪(1/2, 1/2) + Z2. The third explores arithmetic and geometric properties of Z3 by exploiting the algebraic structure of the quaternions and the Gaussian integers.

Localization Properties For The Unitary Anderson Model, Eman F. Hamza

All ETDs from UAB

We study a unitary version of the one-dimensional Anderson model, given by a five diagonal deterministic unitary operator multiplicatively perturbed by a random phase matrix. This operator models the time evolution of an electron in a one-dimensional metal ring subject to a magnetic field that linearly increases with time. We fully characterize positivity and vanishing of the Lyapunov exponent for this model for arbitrary distributions of the random phases. This includes Bernoulli distributions, where in certain cases a finite number of critical spectral values, with vanishing Lyapunov exponent, exists. Thus, we prove that for all non-trivial distributions the model has …

Competition In Multistable Vision Is Attribute-Specific, Jon K. Grossmann

All ETDs from UAB

Ambiguous figures are visual stimuli with multiple competing interpretations. The different possible interpretations are mutually exclusive, and perception fluctuates from one interpretation to the next over time. Natural scenes are inherently ambiguous as well. A pair of two-dimensional retinal images does not instantaneously provide sufficient information to deduce the full three-dimensional layout and identities of objects in the scene. We investigate how the visual system uses internally stored models of objects and scenes to interpret and understand visual information. Ambiguous figures provide an experimental microdomain in which to investigate this top-down process in vision. In one set of experiments, we …