Digital Commons Network^™

Repeat Organic Dust Exposure–Induced Monocyte Inflammation Is Associated With Protein Kinase C Activity, Jill A. Poole, Todd A. Wyatt, Susanna G. Von Essen, John Hervert, Conrad Parks, Tracy Mathisen, Debra J. Romberger

United States Public Health Resources

Background: Organic dust exposure results in an inflammatory response that attenuates over time, but repetitive exposures can result in chronic respiratory diseases. Mechanisms underlying this modulated response are not clear.
Objective: This study investigated the effects of repeat versus single organic dust exposure–induced inflammatory mediators and protein kinase C (PKC) activity in monocytes.
Methods: Settled organic dust was obtained from swine confinement facilities. Promonocytic THP-1 cells and human peripheral blood monocytes were pretreated with or without dust extract and then restimulated. Culture supernatants were evaluated for TNF-α, IL-6, CXCL8, and IL-10. Responses were compared with endotoxin-depleted dust, LPS, and peptidoglycan. …

News From Hope College, Volume 39.1: August, 2007, Hope College

News from Hope College

No abstract provided.

A Functional Analysis Of The Mechanically And Metabolically Sensitive Components Of The Skeletal Muscle Exercise Pressor Reflex In Hypertension, Anna Katherine Leal

Bioengineering Theses - Archive

Background - In hypertension, physical activity creates a risk for adverse cardiac events by causing exaggerated increases in mean arterial pressure (MAP) and heart rate (HR). One physiological mechanism responsible for this cardiovascular hyperactivity is the exercise pressor reflex (EPR). The EPR is a neural pathway originating in skeletal muscle that contributes to cardiovascular regulation during exercise. The EPR is composed of two afferent arms: one is comprised of mostly mechanically sensitive, group III afferent fibers that respond to muscle stretch and pressure, and the other is predominantly metabolically sensitive, group IV afferent fibers that respond to the chemical milieu …

Specters Of Haiti: Race, Fear, And The American Gothic, 1789-1855, Gretchen Judith Woertendyke

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Ensemble Methods For Classification With Applications To Genomics, Melissa Jane Fazzari

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

On (Non)Factivity, Clausal Complementation And The Cp-Field, Carlos Francisco De Cuba

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Testes-Specific Genes Are Evolving Faster Than Their Broadly Expressed Paralogs Due To Reduced Expression Level And Relaxed Functional Constraint, Seiji Kumagai

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Nietzsche's Unconscious And Nineteenth-Century Thought, Joseph Anthony Kranak

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Foreign Body Reactions To Neural Implants In The Brain, Parisa Lotfi

Bioengineering Theses - Archive

Neural implants have been used and studied for many decades. They are applied to record neural signals or to locally deliver drugs. Unfortunately, foreign body reaction and accompanied glial scar formation often lead to implant failure. The lack of knowledge about the molecular mechanism governing foreign body reactions in the brain significantly hinders the development of brain implantable devices with improved safety and biocompatibility. To study the immune responses to brain implants, a novel animal model has been developed and used for the following investigation. Our studies have established cell recruitment time courses of astrocytes, microglial cells, lymphocytes, monocytes and …

Functionalized Nanoparticles For The Selective Killing Of Cancer Cells, Paul Todd Thevenot

Bioengineering Theses - Archive

The use of nanoparticles for cancer imaging and drug delivery has produced some success in improving the efficacy and safety of cancer chemotherapy. It is generally believed that the efficiency of nanoparticle-based cancer therapy would be greatly improved if such particles could be designed to directly interact with and eradicate tumor. Many recent studies have revealed that surface functionality plays an important role in particle:cell interactions. Using titanium dioxide (TiO2) nanoparticles (21 nm diameter) as test subjects, nanoparticles with different functional groups, hydroxyl (-OH), amine (-NH2), and carboxyl (-COOH) were produced and used in this investigation. An in vitro cell …

Jefferson Medical College Annual Report, 2007, Thomas J. Nasca

Jefferson Medical College Administrative Documents and Reports

No abstract provided.

Forage News [2007-08], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• UK All Commodity Field Day
• 8^th Kentucky Grazing Conference
• Hay Hotline Helps Farmers in Search of Forage
• Beware of Hay Payment Scam
• Judge Amends Roundup Ready Alfalfa Ruling
• Corn Acres Soar, Soy Acres Plunge
• Relative Feed Value (RFV) and Relative Forage Quality (RFQ)
• KFGC Awards
• Forage Spokesman Nominations
• Upcoming Events

African Americans And The Struggle For Opportunity In Florida Public Higher Education, 1947–1977, Larry Johnson, Deirdre Cobb-Roberts, Barbara Shircliffe

Educational and Psychological Studies Faculty Publications

In the decades following World War II, access to higher education became an important vehicle for expanding opportunity in the United States. The African American–led Civil Rights Movement challenged discrimination in higher education at a time when state and federal government leaders saw strengthening public higher education as necessary for future economic growth and development. Nationally, the 1947 President’s Commission on Higher Education report Higher Education for American Democracy advocated dismantling racial, geographic, and economic barriers to college by radically expanding public higher education, to be accomplished in large part through the development of community colleges. Although these goals ere …

Species-Specific Visitation And Removal Of Baits For Delivery Of Pharmaceuticals To Feral Swine, Tyler A. Campbell, David B. Long

United States Department of Agriculture Wildlife Services: Staff Publications

Within the domestic swine industry there is growing trepidation about the role feral swine (Sus scrofa) play in the maintenance and transmission of important swine diseases. Innovative disease management tools for feral swine are needed. We used field trials conducted in southern Texas from February to March 2006 to compare species-specific visitation and removal rates of fish-flavored and vegetable-flavored baits with and without commercially available raccoon (Procyon lotor/) repellent (trial 1) and removal rates of baits deployed in a systematic and cluster arrangement (trial 2). During trial 1, 1) cumulative bait removal rates after four nights …

Recovery In A Cynical Time—With Apologies To Eric Arthur Blair, Dale D. Goble

Washington Law Review

The drafters of the Endangered Species Act envisioned a process in which a species at risk of extinction would be protected while the threats it faces are removed so that it recovers. Over the first three decades of experience with the Act, implementation has proved to be far more complex. Recovering at-risk species imposes two different types of requirements. Biologically, recovery is a demographic problem: the species's population must have increased in numbers and dispersed geographically to a point at which nature's random risks have been reduced so that the species is no longer in danger of extinction. The risk-management …

High-Resolution/High-Contrast Mri Of Human Articular Cartilage Lesions., Shadi F. Othman, Jun Li, Osama Abdullah, Jessy J. Moinnes, Richard L. Magin, Carol Muehleman

All Faculty Articles - School of Engineering and Computer Science

BACKGROUND: Magnetic resonance microscopy (MRM) is an important experimental tool in the identification of early cartilage lesions.

METHODS: Normal and degenerated cartilage samples were imaged at 11.74 T using a standard spin echo sequence. Quantitative MR measurements for T1, T2, and ADC were obtained and mapping for T2 and ADC was performed. The bi-exponential model for T2 relaxation was also explored. Histology was carried out for comparison with MR images.

RESULTS: MR images of cartilage samples displaying early stages of degeneration were positively correlated to their histological appearance in 23-microm high-resolution images and also with much shorter imaging times at …

Derivation Of The Lineage And Function In Tumor Angiogenesis Of Bone Marrow-Derived Endothelial Cells, Daniel Joseph Nolan

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Physical Exercise Increases Hippocampal Cell Loss In A Model Of Epilepsy, Nefta Ayisha Mitchell

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Mmp-7 Modulates The Transition Of Normal Pancreatic Acinar Cells To Metaplastic Ducts Associated With The Neoplastic Epithelium Of Pancreatic Ductal Adenocarcinoma, Johnny Johnson

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Acceptance Of Evolution And Knowledge Of Related Scientific Tenets: A Survey Of Science Center Visitors, Dustin Growick

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Structure-Function Studies On Mammalian Mitochondrial Dna Polymerase, Zhixin Chen

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Who, If I Cry Out, Would Hear Me Among The Angels, Hsiu-Hsiu Chang

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Chemical Signature Of A Sewage Plume From A Cesspool, Long Island, New York, Xuan Xu

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Modeling Biotic Causes Of Extinction: Vertebrate Case Studies At The Intersection Of Evolutionary Ecology, Paleontology, And Conservation Biology., Jeffrey Vincent Yule

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

[to be added]

Never Alone: A "Look" At Imaginal Companions, Mary Koegel

Masters Theses & Specialist Projects

American culture tends to consider imaginary friends (or imaginal companions, as I refer to them) as a folk belief belonging in the realm of childhood. If an adult believes in imaginal companions, they are potentially subject to the social stigma of psychological labeling. The mass media reflects this perception of reality and influences social interactions regarding experiences and beliefs in imaginal companions. Fear of this social stigma limits folk group size, which potentially creates an issue with informant group size. I gathered my informants from a group of friends, whom I interviewed over a one-year period. Although there is a …

Seed Toughness In Persea Americana (Lauraceae) And Dioclea Reflexa (Papilionaceae) And Feeding Behavior In Agoutis (Dasyprocta Punctata), 2007, Maria Peterson

Monteverde Institute: Tropical Ecology and Conservation

Agoutis are a common study subject because of their caching behavior and for their role in seed dispersal in the tropics (Wainwright 2002). This study examined the relationship between the hardness of seed coats and their rate of consumption by conducting trials at eight known agouti territories in Monteverde, Costa Rica using softened and untreated seeds. Trials were conducted separately for each seed species. A significant difference was found between the number of hard and soft seeds of Persea americana and Dioclea reflexa left behind at the sites. According to statistical tests, agoutis seem to prefer softer seeds of P. …

Typed Document: Classroom Notes, Edna Louise Saffy

Saffy Collection - All Textual Materials

Dr. Saffy's notes for classes held 8:00 Tuesday and Thursday, August 30-September 25, 2007.

Extended Visions, July/August 2007

Extended Visions Newsletter (ARDC)

Contents:
ARDC Director's Comments
ARDC FEATURE UNIT - Agronomy Research Area
About the People
Agronomy Research at the ARDC
Sweet Sorghum, the Sugarcane of the Midwest
Bringing It Into Focus
Calendar of Events
Controlling Tomato Leaf Spot Diseases
Drought Conditions Under a Tent
Extension Summer Intern
Late Season Crop Management Diagnostic Clinic - Aug. 24
Saunders County Fair Schedule

Exogenous Farnesol Interferes With The Normal Progression Of Cytokine Expression During Candidiasis In A Mouse Model, Dhammika H. M. L. P. Navarathna, Kenneth W. Nickerson, Gerald E. Duhamel, Thomas R. Jerrels, Thomas M. Petro

Papers in Microbiology

Candida albicans, a dimorphic fungus composed of yeast and mycelial forms, is the most common human fungal pathogen. Th1 cytokines such as interleukin-2 (IL-2), gamma interferon (IFN-γ), and tumor necrosis factor alpha (TNF-α), which are induced by macrophage IL-12, are critical to resistance against systemic candidiasis, while Th2 cytokines such as IL-4 and IL-5 are less critical. Farnesol is a quorum-sensing molecule produced by C. albicans that controls the formation of mycelia but is also a virulence factor. To determine whether farnesol enhances the virulence of C. albicans by modulating the production of Th1 and Th2 cytokines, mice were …

The Spitfire Grill, Otterbein University Theatre And Dance Department

2007 Summer Theatre

After being released from jail, Percy Talbott travels to a town in Maine looking for a new beginning. When she arrives, she finds work at a restaurant owned by the crabby Hannah. She also befriends a waitress named Shelby and begins a romance with an attractive local named Joe. But when Hannah falls ill and Percy plans to help her sell the restaurant, Shelby's husband becomes suspicious of her intentions. https://en.wikipedia.org/wiki/The_Spitfire_Grill_(musical)