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2007

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Articles 11101 - 11130 of 12223

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Evolutionary Theory And Political Leadership: Why Certain People Do Not Trust Decision Makers, Kevin Smith, Christopher W. Larimer, Levente Littvay, John Hibbing Jan 2007

Evolutionary Theory And Political Leadership: Why Certain People Do Not Trust Decision Makers, Kevin Smith, Christopher W. Larimer, Levente Littvay, John Hibbing

Department of Political Science: Faculty Publications

Central to social systems are the attitudes of the rank and file toward those who make political decisions (leaders), and attitudes toward leaders are known to be characterized by two fundamental features. First, the modal attitude is acceptance of the necessity of leaders coupled with acute aversion to leaders who are believed to be motivated by ambition and avarice; second, people are highly variable with some being markedly more sensitive than others to the traits of leaders. But the theoretical basis for these empirical facts has yet to be fully elucidated. In this article, we offer such a theory by …

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Differential Engagement Of Tim-1 During Activation Can Positively Or Negatively Costimulate T Cell Expansion And Effector Function, Vijay K. Kuchroo, Sheng Xiao, Nader Najafian, Jay Reddy, Monica Albin, Chen Zhu, Eric Jensen, Jaimie Imitola, Thomas Korn, Ana C. Anderson, Zheng Zhang, Cristina Gutierrez, Thomas Moll, Raymond A. Sobel, Dale T. Umetsu, Hideo Yagita, Hisaya Akiba, Terry Strom, Mohamed H. Sayegh, Rosemarie H. Dekruyff, Samia J. Khoury Jan 2007

Differential Engagement Of Tim-1 During Activation Can Positively Or Negatively Costimulate T Cell Expansion And Effector Function, Vijay K. Kuchroo, Sheng Xiao, Nader Najafian, Jay Reddy, Monica Albin, Chen Zhu, Eric Jensen, Jaimie Imitola, Thomas Korn, Ana C. Anderson, Zheng Zhang, Cristina Gutierrez, Thomas Moll, Raymond A. Sobel, Dale T. Umetsu, Hideo Yagita, Hisaya Akiba, Terry Strom, Mohamed H. Sayegh, Rosemarie H. Dekruyff, Samia J. Khoury

School of Veterinary and Biomedical Sciences: Faculty Publications

It has been suggested that T cell immunoglobulin mucin (Tim)-1 expressed on T cells serves to positively costimulate T cell responses. However, crosslinking of Tim-1 by its ligand Tim-4 resulted in either activation or inhibition of T cell responses, thus raising the issue of whether Tim-1 can have a dual function as a costimulator. To resolve this issue, we tested a series of monoclonal antibodies specifi c for Tim-1 and identifi ed two antibodies that showed opposite functional effects. One anti–Tim-1 antibody increased the frequency of antigen-specifi c T cells, the production of the proinfl ammatory cytokines IFN-γ and IL-17, …

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A Protein Encoded By The Bovine Herpesvirus 1 Latency-Related Gene Interacts With Specific Cellular Regulatory Proteins, Including Ccaat Enhancer Binding Protein Alpha, Florencia Meyer, Sandra Perez, Vicki Geiser, Mark Sintek, Melissa Inman, Clinton J. Jones Jan 2007

A Protein Encoded By The Bovine Herpesvirus 1 Latency-Related Gene Interacts With Specific Cellular Regulatory Proteins, Including Ccaat Enhancer Binding Protein Alpha, Florencia Meyer, Sandra Perez, Vicki Geiser, Mark Sintek, Melissa Inman, Clinton J. Jones

Nebraska Center for Virology: Faculty Publications

Following acute infection, bovine herpesvirus 1 establishes latency in sensory neurons of trigeminal ganglia (TG). Reactivation from latency occurs periodically, resulting in the shedding of infectious virus. The latency-related (LR) RNA is abundantly expressed in TG of latently infected calves, and the expression of LR proteins is necessary for dexamethasone-induced reactivation from latency. Previously published studies also identified an alternatively spliced LR transcript which is abundantly expressed in TG at 7 days after infection and has the potential to encode a novel LR fusion protein. Seven days after infection is when extensive viral gene expression is extinguished in TG and …

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Modulation Of Cd4 Co-Receptor Limits Spontaneous Autoimmunity When High-Affinity Transgenic Tcr Specific For Self-Antigen Is Expressed On A Genetically Resistant Background, Zsolt Illés, Hanspeter Waldner, Jay Reddy, Ana C. Anderson, Raymond A. Sobel, Vijay K. Kuchroo Jan 2007

Modulation Of Cd4 Co-Receptor Limits Spontaneous Autoimmunity When High-Affinity Transgenic Tcr Specific For Self-Antigen Is Expressed On A Genetically Resistant Background, Zsolt Illés, Hanspeter Waldner, Jay Reddy, Ana C. Anderson, Raymond A. Sobel, Vijay K. Kuchroo

Jay Reddy Publications

Myelin proteolipid protein (PLP) 139–151 is an immunodominant peptide that induces experimental autoimmune encephalomyelitis (EAE) in H-2s SJL/J mice. While PLP 139–151-specific TCR transgenic (tg) 4E3 mice develop fulminant spontaneous disease on the susceptible SJL/J background, spontaneous EAE is dramatically reduced on the H-2s congenic B10.S background. On this resistant background, we observed a high frequency of positively selected tg CD42CD82 (DN) thymocytes and peripheral DN tg T cells. Splenic DN tg T cells responded to anti-CD3 stimulation similarly to CD41 cells, but proliferative and cytokine responses to PLP 139–151 were blunted, implying that CD4 coreceptor down-regulation modulated …

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Su.32. Myelin-Specific Regulatory T Cells Accumulate In The Central Nervous System, But Fail To Suppress Pathogenic Effector T Cells At The Peak Of Autoimmune Inflammation [Abstract Only], Thomas Korn, Mohamed Oukka, Jay Reddy, Estelle Betelli, Amit Awasthi, Raymond Sobel, Kai Wucherpfennig, Vijay K. Kuchroo Jan 2007

Su.32. Myelin-Specific Regulatory T Cells Accumulate In The Central Nervous System, But Fail To Suppress Pathogenic Effector T Cells At The Peak Of Autoimmune Inflammation [Abstract Only], Thomas Korn, Mohamed Oukka, Jay Reddy, Estelle Betelli, Amit Awasthi, Raymond Sobel, Kai Wucherpfennig, Vijay K. Kuchroo

Jay Reddy Publications

Treatment with ex vivo generated regulatory T cells (Treg) has been regarded as highly attractive therapeutic approach for autoimmune diseases. However, the dynamics and function of T-reg in autoimmunity are not well understood. Thus, we developed Foxp3gfp “knock-in” mice and myelin oligodendrocyte glycoprotein (MOG)35–55/IAb tetramers to track autoantigen-specific effector T cells (T-eff) and T-reg in vivo during experimental autoimmune encephalomyelitis, an animal model for multiple sclerosis. Following immunization with the encephalitogenic peptide MOG35–55 emulsified in complete Freund's adjuvant, MOG35–55-tetramer-reactive, Foxp3+ T-reg expanded in the peripheral lymphoid compartment and readily accumulated in the central nervous system (CNS), but did not prevent …

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Species-Specific Visitation And Removal Of Baits For Delivery Of Pharmaceuticals To Feral Swine, Tyler A. Campbell, David B. Long Jan 2007

Species-Specific Visitation And Removal Of Baits For Delivery Of Pharmaceuticals To Feral Swine, Tyler A. Campbell, David B. Long

United States Department of Agriculture Wildlife Services: Staff Publications

Within the domestic swine industry there is growing trepidation about the role feral swine (Sus scrofa) play in the maintenance and transmission of important swine diseases. Innovative disease management tools for feral swine are needed. We used field trials conducted in southern Texas from February to March 2006 to compare species-specific visitation and removal rates of fish-flavored and vegetable-flavored baits with and without commercially available raccoon (Procyon lotor) repellent (trial 1) and removal rates of baits deployed in a systematic and cluster arrangement (trial 2). During trial 1, 1) cumulative bait removal rates after four nights …

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Review Of Infectious Diseases Of Wild Rodents By Dennis Padovan, Robert G. Mclean Jan 2007

Review Of Infectious Diseases Of Wild Rodents By Dennis Padovan, Robert G. Mclean

United States Department of Agriculture Wildlife Services: Staff Publications

Infectious Diseases of Wild Rodents is a collection of reference material on a wide variety of infectious diseases documented in rodent species throughout the world. Editorially, this was a massive undertaking to provide a comprehensive and systematic coverage of the information on so many rodent species and infectious diseases in one volume. Although the information is not presented in much detail, the breadth of coverage makes this a good reference book for those interested in rodent diseases throughout the world. The information is presented in two different formats: disease information in the first part of the book is arranged by …

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Grassland Composition Affects Season Shifts In Seed Preference By Pogonomyrmex Barbatus (Hymenoptera: Myrmicinae) In The Edwards Plateau, Texas, Nancy Nicolai, Jerry L. Cook, Fred E. Smeins Jan 2007

Grassland Composition Affects Season Shifts In Seed Preference By Pogonomyrmex Barbatus (Hymenoptera: Myrmicinae) In The Edwards Plateau, Texas, Nancy Nicolai, Jerry L. Cook, Fred E. Smeins

Department of Agronomy and Horticulture: Faculty Publications

The effects of season and community composition as generated by livestock herbivory of differing intensity on seed species preference by Pogonomyrmex barbatus (F. Smith) were studied in a semiarid savanna on the Edward’s Plateau, TX. Seasonal differences in nutrient requirements of the colony could lead to differential preferences for seeds harvested in spring and fall. Field cafeteria studies were conducted to test the hypothesis that late successional species, with their high nutrient content, would be chosen regardless of grazing intensity or season. Commercial seeds of known nutrient content were used to test the hypothesis that high protein levels would be …

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World Agriculture And Environment: A Commodity-By-Commodity Guide To Impacts And Practices [Book Review], Charles A. Francis Jan 2007

World Agriculture And Environment: A Commodity-By-Commodity Guide To Impacts And Practices [Book Review], Charles A. Francis

Department of Agronomy and Horticulture: Faculty Publications

This comprehensive reference book provides a good overview of global agriculture at the end of the millennium. In the introduction, author Jason Clay brings his long experience—in farming, teaching, and government service—into the presentation of a balanced perspective on how production must be balanced with concern for the environment. Now with World Wildlife Fund, he couples a background in economics, anthropology and geography with considerable professional experience in aquaculture and cooperation in the private sector to explore multiple aspects of agriculture and food production. He is particularly effective in discussing the economic and environmental sustainability of the food system, although …

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The Ripple Effect: Biofuels, Food Security, And The Environment, Rosamond L. Naylor, Adam Liska, Marshall B. Burke, Walter P. Falcon, Joanne C. Gaskell, Scott D. Rozelle, Kenneth G. Cassman Jan 2007

The Ripple Effect: Biofuels, Food Security, And The Environment, Rosamond L. Naylor, Adam Liska, Marshall B. Burke, Walter P. Falcon, Joanne C. Gaskell, Scott D. Rozelle, Kenneth G. Cassman

Department of Agronomy and Horticulture: Faculty Publications

The integration of the agricultural and energy sectors caused by rapid growth in the biofuels market signals a new era in food policy and sustainable development. For the first time in decades, agricultural commodity markets could experience a sustained increase in prices, breaking the long-term price decline that has benefited food consumers worldwide. Whether this transition occurs—and how it will affect global hunger and poverty—remain to be seen. Will food markets begin to track the volatile energy market in terms of price and availability? Will changes in agricultural commodity markets benefit net food producers and raise farm incomes in poor …

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Plant Species Richness In Relation To Pasture Position, Management, And Scale, John A. Guretzky, Kenneth J. Moore, C. Lee Burras, E. Charles Brummer Jan 2007

Plant Species Richness In Relation To Pasture Position, Management, And Scale, John A. Guretzky, Kenneth J. Moore, C. Lee Burras, E. Charles Brummer

Department of Agronomy and Horticulture: Faculty Publications

The objective of this research was to describe how landscape position, grazing management, and scale affected overall plant species richness and species richness per functional group in temperate pastures located in the central United States. The effects and interactions of summit, backslope, and toeslope positions and continuous, rotational, and nongrazed stocking systems on species richness were examined at sample scales of 0.18 m2 and 4.5 m2. Landscape position explained 40–63% of species richness variation at 0.18 m2 compared to 3–26% at 4.5 m2 for overall, perennial, perennial grass, vegetative-spreading grass, perennial herb, and perennial N …

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Oral Treatment Of Hemophilia, Oral Alpan, Tirumalai Kamala, Polly Matzinger, William Hugold Velander Jan 2007

Oral Treatment Of Hemophilia, Oral Alpan, Tirumalai Kamala, Polly Matzinger, William Hugold Velander

Department of Chemical and Biomolecular Engineering: Faculty Publications

Disclosed herein is a simple method for the treatment of antigen-deficiency diseases, by orally administering to a subject a therapeutically effective amount of the deficient antigen, wherein the antigen is not present in a liposome. In one embodiment, the method increases hemostasis in a subject having hemophilia A or B, by orally administering to the hemophiliac a therapeutically effective amount of the appropriate clotting factor other than in a liposome, sufficient to induce oral tolerance and supply exogenous clotting factor to the subject.

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Barcsoysnp23: A Panel Of 23 Selected Snps For Soybean Cultivar Identification, M. S. Yoon, Q.J. Song, I. Y. Choi, James E. Specht, D. L. Hyten, P. B. Cregan Jan 2007

Barcsoysnp23: A Panel Of 23 Selected Snps For Soybean Cultivar Identification, M. S. Yoon, Q.J. Song, I. Y. Choi, James E. Specht, D. L. Hyten, P. B. Cregan

Department of Agronomy and Horticulture: Faculty Publications

This report describes a set of 23 informative SNPs (BARCSoySNP23) distributed on 19 of the 20 soybean linkage groups that can be used for soybean cultivar identification. Selection of the SNPs to include in this set was made based upon the information provided by each SNP for distinguishing a diverse set of soybean genotypes as well as the linkage map position of each SNP. The genotypes included the ancestors of North American cultivars, modern North American cultivars and a group of Korean cultivars. The procedure used to identify this subset of highly informative SNP markers resulted in a significant increase …

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A “Sprinkler” Vegetative Treatment System, Jason Gross, Chris G. Henry Jan 2007

A “Sprinkler” Vegetative Treatment System, Jason Gross, Chris G. Henry

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

Vegetative Treatment Systems have historically been a practice for the treatment and utilization of open lot livestock wastes. Use of these systems has been rejuvenated in recent years. A “sprinkler” vegetative treatment area (VTA) has been designed and developed as a proof of concept for addressing challenges experienced with small and medium Animal Feeding Operations. The focus of this paper is to report on the design, economics, challenges and the lessons learned on the development of this system. Cost data shows the cost of a “sprinkler” VTS to range between $31 to $63/head, compared to $51 to $170/head for a …

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Protection With Recombinant Clostridium Botulinum C1 And D Binding Domain Subunit (Hc) Vaccines Against C And D Neurotoxins, Robert P. Webb, Theresa J. Smith, Patrick M. Wright, Vicki A. Montgomery, Michael M. Meagher, Leonard A. Smith Jan 2007

Protection With Recombinant Clostridium Botulinum C1 And D Binding Domain Subunit (Hc) Vaccines Against C And D Neurotoxins, Robert P. Webb, Theresa J. Smith, Patrick M. Wright, Vicki A. Montgomery, Michael M. Meagher, Leonard A. Smith

Michael Meagher Publications

Recombinant botulinum Hc (rBoNT Hc) vaccines for serotypes C1 and D were produced in the yeast Pichia pastoris and used to determine protection against four distinct BoNT C and D toxin subtypes. Mice were vaccinated with rBoNT/C1 Hc, rBoNT/D Hc, or with a combination of both vaccines and challenged with BoNT C1, D, C/D, or D/C toxin. Mice receiving monovalent vaccinations were partially or completely protected against homologous toxin and not protected against heterologous toxin. Bivalent vaccine candidates completely survived challenges from all toxins except D/C toxin. These results indicate the recombinant C1 and D Hc vaccines are not only …

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Evolutionary Dynamics Of Eukaryotic Selenoproteomes: Large Selenoproteomes May Associate With Aquatic Life And Small With Terrestrial Life, Alexei Lobanov, Dmitri E. Fomenko, Yan Zhang, Aniruddha Sengupta Jan 2007

Evolutionary Dynamics Of Eukaryotic Selenoproteomes: Large Selenoproteomes May Associate With Aquatic Life And Small With Terrestrial Life, Alexei Lobanov, Dmitri E. Fomenko, Yan Zhang, Aniruddha Sengupta

Vadim Gladyshev Publications

Background: Selenocysteine (Sec) is a selenium-containing amino acid that is co-translationally inserted into nascent polypeptides by recoding UGA codons. Selenoproteins occur in both eukaryotes and prokaryotes, but the selenoprotein content of organisms (selenoproteome) is highly variable and some organisms do not utilize Sec at all.

Results: We analyzed the selenoproteomes of several model eukaryotes and detected 26 and 29 selenoprotein genes in the green algae Ostreococcus tauri and Ostreococcus lucimarinus, respectively, five in the social amoebae Dictyostelium discoideum, three in the fly Drosophila pseudoobscura, and 16 in the diatom Thalassiosira pseudonana, including several new selenoproteins. Distinct …

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Pigeons And People Select Efficient Routes When Solving A One-Way “Traveling Salesperson” Task, Brett M. Gibson, Edward A. Wasserman, Alan C. Kamil Jan 2007

Pigeons And People Select Efficient Routes When Solving A One-Way “Traveling Salesperson” Task, Brett M. Gibson, Edward A. Wasserman, Alan C. Kamil

Papers in Behavior in Biological Sciences

The authors presented people (Experiment 1) and pigeons (Experiments 2 and 3) with a large number of 1-way traveling salesperson problems that consisted of 3, 4, and 5 identical stimuli (nodes) on a computer monitor. The sequence of nodes that each traveler selected was recorded, and the distance of the route was subsequently determined. The routes the pigeons and people selected were reliably more efficient than those used by a Monte Carlo model given the same problems. The pigeons’ routes were significantly less efficient than a nearest neighbor model of performance, however. In Experiment 3, pigeons were required to select …

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Expression, Processing, And Glycosaminoglycan Binding Activity Of The Recombinant Human 315-Kda Hyaluronic Acid Receptor For Endocytosis (Hare), Ed Harris, Svetlana V. Kyosseva, Janet A. Weigel, Paul H. Weigel Jan 2007

Expression, Processing, And Glycosaminoglycan Binding Activity Of The Recombinant Human 315-Kda Hyaluronic Acid Receptor For Endocytosis (Hare), Ed Harris, Svetlana V. Kyosseva, Janet A. Weigel, Paul H. Weigel

Department of Biochemistry: Faculty Publications

The hyaluronic acid (HA) receptor for endocytosis (HARE; also designated stabilin-2 and FEEL-2) mediates systemic clearance of glycosaminoglycans from the circulatory and lymphatic systems via coated pit-mediated uptake. HARE is primarily found as two isoforms (315- and 190-kDa) in sinusoidal endothelial cells of the liver, lymph node, and spleen. Here we characterize the ligand specificity and function of the large stably expressed 315-HARE isoform in Flp-In 293 cell lines. Like human spleen sinusoidal endothelial cells, Flp-In 293 cell lines transfected with a single cDNA encoding the full-length 315-HARE express both the 315-kDa and the proteolytically truncated 190-kDa isoforms in a …

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A New Strategy For Assessing Selenoprotein Function: Sirna Knockdown/Knock-In Targeting The 3'-Utr, Min-Hyuk Yoo, Xue-Ming Xu, Anton A. Turanov, Bradley A. Carlson, Vadim N. Gladyshev, Dolph L. Hatfield Jan 2007

A New Strategy For Assessing Selenoprotein Function: Sirna Knockdown/Knock-In Targeting The 3'-Utr, Min-Hyuk Yoo, Xue-Ming Xu, Anton A. Turanov, Bradley A. Carlson, Vadim N. Gladyshev, Dolph L. Hatfield

Department of Biochemistry: Faculty Publications

Selenocysteine insertion into protein in mammalian cells requires RNA elements in the 3'-untranslated regions (3'-UTRs) of selenoprotein genes. The occurrence of these conserved sequences should make selenoproteins particularly amenable for knockdown/knock-in strategies to examine selenoprotein functions. Herein, we utilized the 3'-UTR of various selenoproteins to knock down their expression using siRNAs and then knock in expression using constructs containing mutations within the target region. Thioredoxin reductase 1 (TR1) knockdown in a mouse kidney cell line resulted in the cells growing about 10% more slowly, being more sensitive to UV radiation, and having increased apoptosis in response to UV than control …

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A Practical Approach To Phylogenomics: The Phylogeny Of Ray-Finned Fish (Actinopterygii) As A Case Study, Chenhong Li, Guillermo Ortí, Gong Zhang, Guoqing Lu Jan 2007

A Practical Approach To Phylogenomics: The Phylogeny Of Ray-Finned Fish (Actinopterygii) As A Case Study, Chenhong Li, Guillermo Ortí, Gong Zhang, Guoqing Lu

School of Biological Sciences: Faculty Publications

Background: Molecular systematics occupies one of the central stages in biology in the genomic era, ushered in by unprecedented progress in DNA technology. The inference of organismal phylogeny is now based on many independent genetic loci, a widely accepted approach to assemble the tree of life. Surprisingly, this approach is hindered by lack of appropriate nuclear gene markers for many taxonomic groups especially at high taxonomic level, partially due to the lack of tools for efficiently developing new phylogenetic makers. We report here a genome-comparison strategy to identifying nuclear gene markers for phylogenetic inference and apply it to the …

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Habitat Area Affects Arthropd Communities Directly And Indirectly Through Top Predators, Örjan Östman, Nicholas W. Griffin, Jared L. Strasburg, Jennifer A. Brisson, Alan R. Templeton, Tiffany M. Knight, Jonathan M. Chase Jan 2007

Habitat Area Affects Arthropd Communities Directly And Indirectly Through Top Predators, Örjan Östman, Nicholas W. Griffin, Jared L. Strasburg, Jennifer A. Brisson, Alan R. Templeton, Tiffany M. Knight, Jonathan M. Chase

School of Biological Sciences: Faculty Publications

Both habitat area and predators are known to affect the diversity and composition of species that live in a locality. In addition, habitat area can influence the presence of predators, indirectly affecting the diversity of prey. Thus, habitat area may influence species diversity directly and indirectly through the presence of top predators. Here we examine the effects of habitat area and predators on the species richness and composition of a foliage living arthropod community in a fragmented complex of glades (small grassland patches within a forested matrix) in the Ozark Plateau, Missouri. We find that a top predator, the eastern …

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Germ-Line Chimerism And Paternal Care In Marmosets (Callithrix Kuhlii), C. N. Ross, J. A. French, Guillermo Ortí Jan 2007

Germ-Line Chimerism And Paternal Care In Marmosets (Callithrix Kuhlii), C. N. Ross, J. A. French, Guillermo Ortí

School of Biological Sciences: Faculty Publications

The formation of viable genetic chimeras in mammals through the transfer of cells between siblings in utero is rare. Using microsatellite DNA markers, we show here that chimerism in marmoset (Callithrix kuhlii) twins is not limited to blood-derived hematopoietic tissues as was previously described. All somatic tissue types sampled were found to be chimeric. Notably, chimerism was demonstrated to be present in germ-line tissues, an event never before documented as naturally occurring in a primate. In fact, we found that chimeric marmosets often transmit sibling alleles acquired in utero to their own offspring. Thus, an individual that contributes …

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Origin Of The Bacterial Set Domain Genes: Vertical Or Horizontal?, Raul Alvarez-Venegas, Monther Sadder, Alexander Tikhonov, Zoya Avramova Jan 2007

Origin Of The Bacterial Set Domain Genes: Vertical Or Horizontal?, Raul Alvarez-Venegas, Monther Sadder, Alexander Tikhonov, Zoya Avramova

School of Biological Sciences: Faculty Publications

The presence of Supressor of variegation-Enhanser of zeste-Trithorax (SET) domain genes in bacteria is a current paradigm for lateral genetic exchange between eukaryotes and prokaryotes. Because a major function of SET domain proteins is the chemical modification of chromatin and bacteria do not have chromatin, there is no apparent functional requirement for the existence of bacterial SET domain genes. Consequently, their finding in only a small fraction of pathogenic and symbiotic bacteria was taken as evidence that bacteria have obtained the SET domain genes from their hosts. Furthermore, it was proposed that the products of the genes would, most likely, …

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The Arabidopsis Homologs Of Trithorax (Atx1) And Enhancer Of Zeste (Clf) Establish ‘Bivalent Chromatin Marks’ At The Silent Agamous Locus, Abdelaty Saleh, Ayed Al-Abdallat, Ivan Ndamukong, Raul Alvarez-Venegas, Zoya Avramova Jan 2007

The Arabidopsis Homologs Of Trithorax (Atx1) And Enhancer Of Zeste (Clf) Establish ‘Bivalent Chromatin Marks’ At The Silent Agamous Locus, Abdelaty Saleh, Ayed Al-Abdallat, Ivan Ndamukong, Raul Alvarez-Venegas, Zoya Avramova

School of Biological Sciences: Faculty Publications

Tightly balanced antagonism between the Polycomb group (PcG) and the Trithorax group (TrxG) complexes maintain Hox expression patterns in Drosophila and murine model systems. Factors belonging to the PcG/TrxG complexes control various processes in plants as well but whether they participate in mechanisms that antagonize, balance or maintain each other’s effects at a particular gene locus is unknown. CURLY LEAF (CLF), an Arabidopsis homolog of enhancer of zeste (EZ) and the ARABIDOPSIS HOMOLOG OF TRITHORAX (ATX1) control the expression of the flower homeotic gene AGAMOUS (AG). Disrupted ATX1 or CLF function results in misexpression of AG, recognizable …

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Virgin Birth In A Hammerhead Shark, Demian D. Chapman, Mahmood S. Shivji, Ed Louis, Julie Sommer, Hugh Fletcher, Paulo A. Prodöhl Jan 2007

Virgin Birth In A Hammerhead Shark, Demian D. Chapman, Mahmood S. Shivji, Ed Louis, Julie Sommer, Hugh Fletcher, Paulo A. Prodöhl

School of Biological Sciences: Faculty Publications

Parthenogenesis has been documented in all major jawed vertebrate lineages except mammals and cartilaginous fishes (class Chondrichthyes: sharks, batoids and chimeras). Reports of captive female sharks giving birth despite being held in the extended absence of males have generally been ascribed to prior matings coupled with long-term sperm storage by the females. Here, we provide the first genetic evidence for chondrichthyan parthenogenesis, involving a hammerhead shark (Sphyrna tiburo). This finding also broadens the known occurrence of a specific type of asexual development (automictic parthenogenesis) among vertebrates, extending recently raised concerns about the potential negative effect of this type …

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Geographic Distribution: Ramphotyphlops Braminus (Brahminy Blindsnake). Usa: Florida: Volusia Co, Louis A. Somma, Paul E. Skelley Jan 2007

Geographic Distribution: Ramphotyphlops Braminus (Brahminy Blindsnake). Usa: Florida: Volusia Co, Louis A. Somma, Paul E. Skelley

Papers in Herpetology

RAMPHOTYPHLOPS BRAMINUS (Brahminy Blindsnake). USA: FLORIDA: VOLUSIA Co.: New Smyrna Beach. 23Septernber 2006. Collected by Stacy Simmons. Verified by Kenneth L. Krysko, Florida Museum ofN atural History, University of Florida. One individual found on floor of residence. UF 151313. First county record. Originally turned in to Division of Plant Industry (DPI) , Florida Department of Agriculture and Consumer Services, Gainesville, Florida, as a "worm for ID" on 27 September 2006; Entomology Log No. 6879. It is not clear if this single specimen indicates an established breeding colony in this county. However, this invasive, parthenogenic exotic is established in other Florida …

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Genome-Enabled Hitchhiking Mapping Identifies Qtls For Stress Resistance In Natural Drosophila, Sergey V. Nuzhdin, Lawrence G. Harshman, M. Zhou, K. Harmon Jan 2007

Genome-Enabled Hitchhiking Mapping Identifies Qtls For Stress Resistance In Natural Drosophila, Sergey V. Nuzhdin, Lawrence G. Harshman, M. Zhou, K. Harmon

Lawrence G. Harshman Publications

Identification of genes underlying complex traits is an important problem. Quantitative trait loci (QTL) are mapped using marker-trait co-segregation in large panels of recombinant genotypes. Most frequently, recombinant inbred lines derived from two isogenic parents are used. Segregation pat-terns are also studied in pedigrees from multiple families. Great advances have been made through creative use of these techniques, but narrow sampling and inadequate power represent strong limi-tations. Here, we propose an approach combining the strengths of both techniques. We established a mapping population from a sample of natural genotypes and applied artificial selection for a com-plex character. Selection changed the …

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Asymmetric Localizations Of Lin-17/Fz And Mig-5/Dsh Are Involved In The Asymmetric B Cell Division In C. Elegans, Mingfu Wu, Michael A. Herman Jan 2007

Asymmetric Localizations Of Lin-17/Fz And Mig-5/Dsh Are Involved In The Asymmetric B Cell Division In C. Elegans, Mingfu Wu, Michael A. Herman

School of Biological Sciences: Faculty Publications

LIN-44/Wnt and LIN-17/Frizzled (Fz) function in a planar cell polarity (PCP)-like pathway to regulate the asymmetric B cell division in Caenorhabditis elegans. We observed asymmetric localization of LIN-17/Frizzled (Fz) and MIG-5/Disheveled (Dsh) during the B cell division. LIN-17∷GFP was asymmetrically localized within the B cell prior to and after the B cell division and correlated with B cell polarity. Asymmetric localization of LIN-17∷GFP was dependent upon LIN-44/Wnt and MIG-5/Dsh function. The LIN-17 transmembrane domain and a portion of the cysteine-rich domain (CRD) were required for LIN-17 function and asymmetric distribution to the B cell daughters, while the conserved KTXXXW …

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Spatiotemporal Variations In Growing Season Exchanges Of Co2, H2o, And Sensible Heat In Agricultural Fields Of The Southern Great Plains, Marc L. Fischer, Dave P. Billesbach, Joseph A. Berry, William J. Riley, Margaret S. Torn Jan 2007

Spatiotemporal Variations In Growing Season Exchanges Of Co2, H2o, And Sensible Heat In Agricultural Fields Of The Southern Great Plains, Marc L. Fischer, Dave P. Billesbach, Joseph A. Berry, William J. Riley, Margaret S. Torn

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Climate, vegetation cover, and management create finescale heterogeneity in unirrigated agricultural regions, with important but not well quantified consequences for spatial and temporal variations in surface CO2, water, and heat fluxes. Eddy covariance fluxes were measured in seven agricultural fields—comprising winter wheat, pasture, and sorghum—in the U.S. Southern Great Plains (SGP) during the 2001–03 growing seasons. Land cover was the dominant source of variation in surface fluxes, with 50%–100% differences between fields planted in winter–spring versus fields planted in summer. Interannual variation was driven mainly by precipitation, which varied more than twofold between years. Peak aboveground biomass and growing season …

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Evolutionary Endocrinology: The Developing Synthesis Between Endocrinology And Evolutionary Genetics, Anthony J. Zera, Lawrence G. Harshman, Tony D. Williams Jan 2007

Evolutionary Endocrinology: The Developing Synthesis Between Endocrinology And Evolutionary Genetics, Anthony J. Zera, Lawrence G. Harshman, Tony D. Williams

Anthony Zera Publications

A productive synthesis of endocrinology and evolutionary genetics has occurred during the past two decades, resulting in the first direct documentation of genetic variation and correlation for endocrine regulators in nondomesticated animals. In a number of insect genetic polymorphisms (dispersal polymorphism in crickets, butterfly wing-pattern polymorphism), blood levels of ecdysteroids and juvenile hormone covary with morphology, development, and life history. Genetic variation in insulin signaling may underlie life history trade-offs in Drosophila. Vertebrate studies identified variation in brain neurohormones, bone-regulating hormones, and hormone receptor gene sequences that underlie ecologically important genetic polymorphisms. Most work to date has focused on genetically …

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