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2006

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Saudi Medical Journal. Maintaining The Previous, Achieving More Progress, Saleh M. Al-Deeb Jan 2006

Saudi Medical Journal. Maintaining The Previous, Achieving More Progress, Saleh M. Al-Deeb

Saudi Medical Journal

No abstract provided.

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Molecular Basis Of Breast Cancer, Layla J. Al-Mansouri, Majed S. Alokail Jan 2006

Molecular Basis Of Breast Cancer, Layla J. Al-Mansouri, Majed S. Alokail

Saudi Medical Journal

Breast cancer is the most frequent cancer in women and represents the second leading cause of cancer death among women after lung cancer. A common phenotypic abnormality of breast cancer cells is dysregulation of cell cycle control. The transformation of normal cell to a cancer cell appears to depend on mutation in genes that normally control cell cycle progression, thus leading to loss of the regulatory cell growth. We summarize here the molecular regulation of mammary carcinoma with regards to the most prominent oncogenes and tumor suppressor genes and their outcome in terms of cellular prognosis, and tumor development.

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Echocardiographic Study Of Aortic Root Diameter In Healthy Children, Piraye Kervancioglu, Mehmet Kervancioglu, Cudi M. Tuncer Jan 2006

Echocardiographic Study Of Aortic Root Diameter In Healthy Children, Piraye Kervancioglu, Mehmet Kervancioglu, Cudi M. Tuncer

Saudi Medical Journal

OBJECTIVE: Echocardiography is commonly used to measure the internal diameter of aortic root, which provides the evaluation of aortic root dilatation. Aortic root dilatation provide information concerning prognosis of aortic regurgitation and predisposition to aortic root dissection or rupture. The purpose of the study was to create normal values for aortic root diameters by using echocardiography in healthy children. METHODS: We obtained the aortic root diameters in 229 normal children, aged one day to 15 years by using M-mode echocardiography. We performed the echocardiograms from the Department of Pediatric Echocardiography Laboratory, Medical Faculty, Dicle University, Turkey. We divided the children …

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Evaluation Of A New Dot Blot Assay For Confirmation Of Human Immunodeficiency Virus Type 1 And 2 Infections Using Recombinant P24, Gp41, Gp120 And Gp36 Antigens, Mehrdad Ravanshad, Farzaneh Sabahi, Fereidoun Mahboudi, Anoshirvan Kazemnejad Jan 2006

Evaluation Of A New Dot Blot Assay For Confirmation Of Human Immunodeficiency Virus Type 1 And 2 Infections Using Recombinant P24, Gp41, Gp120 And Gp36 Antigens, Mehrdad Ravanshad, Farzaneh Sabahi, Fereidoun Mahboudi, Anoshirvan Kazemnejad

Saudi Medical Journal

OBJECTIVE: A sensitive and accurate dot blot assay using recombinant p24 (gag), gp41 and gp120 (env) proteins of HIV-1 and also recombinant gp36, the specific HIV-2 antigen was developed to confirm the presence of antibodies in sera reactive in screening enzyme-linked immunosorbent assays. METHODS: We collected sera from Iranian 125 confirmed HIV positive Iranian samples (seropositive group) from AIDS patients, asymptomatic HIV-infected subjects, HIV-infected intravenous drug users and also hemophilic infected subjects. The samples were obtained from the AIDS Specimen Bank, Pasture Institute, Iran during 2002 to 2003. We also obtained 180 samples (seronegative group) from healthy blood donors. Recombinant …

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Prevalence Of Extended-Spectrum Beta-Lactamases Among Enterobacteriaceae Isolated From Blood Culture In A Tertiary Care Hospital, Noura A. El-Khizzi, Saadia M. Bakheshwain Jan 2006

Prevalence Of Extended-Spectrum Beta-Lactamases Among Enterobacteriaceae Isolated From Blood Culture In A Tertiary Care Hospital, Noura A. El-Khizzi, Saadia M. Bakheshwain

Saudi Medical Journal

OBJECTIVE: To determine the prevalence of extended spectrum beta-lactamase among Enterobacteriaceae isolated from blood culture in a tertiary care hospital. METHODS: We carried out this study at the Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia during the period between January 2003-December 2004. We tested a total of 601 isolates of the family Enterobacteriaceae from blood culture for the prevalence of extended spectrum beta-lactamase (ESBL) production by the standardized disc diffusion method and confirmed by the ESBL E test strips. RESULTS: Ninety-five (15.8%) of the isolates were ESBL producers. Among these, 48.4% were Klebsiella pneumoniae (K. pneumoniae) followed by15.8% of …

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A Study Of Bacterial Isolates From Corneal Specimens And Their Antibiotic Resistance Profile, Nurun N. Begum, Abdulaziz S. Al-Khattaf, Samir M. Al-Mansouri, Edward A. Yeboah, Abdel-Mageed M. Kambal Jan 2006

A Study Of Bacterial Isolates From Corneal Specimens And Their Antibiotic Resistance Profile, Nurun N. Begum, Abdulaziz S. Al-Khattaf, Samir M. Al-Mansouri, Edward A. Yeboah, Abdel-Mageed M. Kambal

Saudi Medical Journal

OBJECTIVE: We aim to examine the spectrum of bacteria causing corneal infections and their antibiotic susceptibility patterns. This will serve as a guideline for empiric therapy of corneal infections. METHODS: We conducted the study over a period of 18 months from March 2001 through December 2002 in King Abdul-Aziz University Hospital, Riyadh, Kingdom of Saudi Arabia. Corneal specimens taken from 200 patients were inoculated directly onto different types of media. The isolates were identified and then tested against the appropriate topical or systemic antibiotics. RESULTS: Sixty-seven (33.5%) of the total specimens were culture positive and 133 (66.5%) were culture negative. …

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Ventilator-Associated Pneumonia In Surgical Emergency Intensive Care Unit, Bulent M. Ertugrul, Ayse Yildirim, Pinar Ay, Serkan Oncu, Atahan Cagatay, Nahit Cakar, Cemalettin Ertekin, Halit Ozsut, Haluk Eraksoy, Semra Calangu Jan 2006

Ventilator-Associated Pneumonia In Surgical Emergency Intensive Care Unit, Bulent M. Ertugrul, Ayse Yildirim, Pinar Ay, Serkan Oncu, Atahan Cagatay, Nahit Cakar, Cemalettin Ertekin, Halit Ozsut, Haluk Eraksoy, Semra Calangu

Saudi Medical Journal

OBJECTIVE: To investigate the incidence, risk factors and the etiology of ventilator-associated pneumonia (VAP) in surgical emergency intensive care unit (ICU) patients. METHODS: We conducted this prospective cohort study in the surgical emergency ICU of Istanbul Medical Faculty between December 1999 and May 2001. We included 100 mechanically ventilated patients in this study. We diagnosed VAP according to the current diagnostic criteria. We identified the etiology of VAP cases by both quantitative cultures of endotracheal aspiration and blood cultures. To analyze the predisposing factors for the development of VAP, we recorded the following variables: age, gender, acute physiology and chronic …

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A Serological Survey Of Measles, Mumps And Rubella Immunity Among School Aged Children In Western Saudi Arabia, Soad M. Jaber Jan 2006

A Serological Survey Of Measles, Mumps And Rubella Immunity Among School Aged Children In Western Saudi Arabia, Soad M. Jaber

Saudi Medical Journal

OBJECTIVE: To evaluate the adequacy of measles, mumps and rubella (MMR) vaccination among children and to assess risk of outbreak in Jeddah, Kingdom of Saudi Arabia (KSA). METHODS: We recruited a total of 527 children from schools located at different urban regions, and preschool children from those attending the well baby clinics in Jeddah, KSA. We tested for MMR viruses antibodies using ELISA technique. RESULTS: Approximately 99% of children received MMR vaccine. Overall seropositivity for measles antibodies was 71%, mumps 65% and rubella 90%, which were elevated in vaccinated versus non-vaccinated children (p<0.000). In vaccinated children, percentage of seropositivity for MMR was higher in public school children versus private (p<0.01) or those who did not attend school (p<0.01) and in Saudi versus non-Saudi children (p<0.000). In vaccinated children, percentage of seropositivity obtained according to age groups of 4-6 years for measles was 73.7%, for mumps 66.7% and for rubella 91.7%. As for 7-11 years age group, seropositivity for measles was 72.6%, for mumps 68.1% and for rubella 93%, while for the 12-14 years, seropositivity for measles was 66.4%, mumps 59.1% and for rubella 86.1%. The prevalence of seropositivity against the above-mentioned viruses decreased with progression of age. CONCLUSION: Measles, mumps and rubella mass vaccination program achieved high coverage rate among children, in Jeddah, KSA. However, there is still a high level of sera negative children among vaccinated ones for measles and mumps. Seropositivity decreased with age, which might raise possibility of outbreaks among adolescent. Additional doses of vaccine against measles and mumps are recommended and evaluation of new MMR protocol should be made.

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Spectrum Of General Surgical Problems In The Developmentally Disabled Adults, Kamran Khalid, Saleh M. Al-Salamah Jan 2006

Spectrum Of General Surgical Problems In The Developmentally Disabled Adults, Kamran Khalid, Saleh M. Al-Salamah

Saudi Medical Journal

OBJECTIVE: This study highlights the spectrum of general surgical problems necessitating admission on intellectually disabled adult patients. Problems encountered in the management and the ways to overcome various difficulties are highlighted. METHODS: Prospective collection of data on 63 consecutive developmentally disabled adult patients admitted to the Department of General Surgery, Riyadh Medical Complex (RMC), Riyadh, Kingdom of Saudi Arabia for various indications from January 2000 through December 2004. Demographic details, clinical presentation, diagnostic modalities, associated physical and neurological disabilities, coexisting medical condition, treatment options, morbidity and mortality were analyzed. Various difficulties encountered during the management and mean to overcome these …

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Associated Risk Factors With Ante-Partum Intra-Uterine Fetal Death, Lamia A. Shaaban, Rihab A. Al-Saleh, Buthina M. Alwafi, Rajaa M. Al-Raddadi Jan 2006

Associated Risk Factors With Ante-Partum Intra-Uterine Fetal Death, Lamia A. Shaaban, Rihab A. Al-Saleh, Buthina M. Alwafi, Rajaa M. Al-Raddadi

Saudi Medical Journal

OBJECTIVE: To determine ante-partum maternal risk factors for intrauterine fetal death. METHODS: We carried out a case control retrospective study, at the Maternity and Children9s Hospital, Jeddah, Kingdom of Saudi Arabia. We included all pregnant women diagnosed as singleton intra-uterine fetal death in the third trimester with fetal weight of 1500 gm and more, admitted to the hospital over a 2-year (2001-2002) period (study group). We examined the following risk factors: diabetes, hypertension, abruptio-placenta, age, gestational age, parity, trauma, sepsis, booking, chromosomal abnormality, previous history of intra-uterine fetal death (IUFD) and intra-uterine growth restriction (IUGR). We compared the results to …

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The Persian Version Of The Cardiff Acne Disability Index. Reliability And Validity Study, Shahin Aghaei, Nazila Mazharinia, Peyman Jafari, Zahra Abbasfard Jan 2006

The Persian Version Of The Cardiff Acne Disability Index. Reliability And Validity Study, Shahin Aghaei, Nazila Mazharinia, Peyman Jafari, Zahra Abbasfard

Saudi Medical Journal

OBJECTIVE: The Cardiff Acne Disability Index (CADI) assesses the impact of acne on a patients life. The aim of the present study was to translate the CADI into Persian language and to validate the Persian version. METHODS: Using standard forward-backward translation, 2 bilinguals translated the CADI into Persian language. We back translated it into English and the final version was provided. We conducted this study from February through December 2004 on 100 patients with acne attending the Department of Dermatology, Jahrom Medical School, Jahrom, Iran who completed the Persian version of the CADI questionnaire. We carried out all statistical analyses …

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Treatment Of Acne Vulgaris With 2% Topical Tea Lotion, Khalifa E. Sharquie, Ihsan A. Al-Turfi, Wathik M. Al-Shimary Jan 2006

Treatment Of Acne Vulgaris With 2% Topical Tea Lotion, Khalifa E. Sharquie, Ihsan A. Al-Turfi, Wathik M. Al-Shimary

Saudi Medical Journal

OBJECTIVE: To use 2% tea lotion as natural plant remedy in the treatment of acne vulgaris. METHODS: We conducted this study in the Department of Dermatology and Venereology in Baghdad Teaching Hospital, Iraq during the period between October 2002 and October 2004. In this single blind randomly controlled therapeutic study, we enrolled 60 patients, their ages ranged from 14-22 years. There were 35 females and 25 males. We divided the patients equally into 2 groups; we instructed group A to use freshly prepared 2% tea lotion twice daily for 2 months, while group B used a control solution. We graded …

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Epidemiology Of Travel-Related Malaria In A Non-Malarious Area In Saudi Arabia, Jaffar A. Al-Tawfiq Jan 2006

Epidemiology Of Travel-Related Malaria In A Non-Malarious Area In Saudi Arabia, Jaffar A. Al-Tawfiq

Saudi Medical Journal

OBJECTIVE: The study describes the epidemiology of malaria in the Eastern Province of Saudi Arabia and the species of Plasmodium causing the disease and the associated factors. METHODS: This is a retrospective study of the epidemiology of malaria at Saudi Aramco Medical Services Organization in Dhahran, Eastern Province of Saudi Arabia. The study included all patients with malaria from January 1994 to June 2005. We retrieved the cases from the archive epidemiology records on all notifiable diseases. The medical records of patients were reviewed and the following information was collected: age, gender, nationality, year and month of acquisition, travel history …

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Antimony-Induced Cerebellar Ataxia, Ammar E. Ahmed, Ahmed M. Musa, Muna H. Hussein Jan 2006

Antimony-Induced Cerebellar Ataxia, Ammar E. Ahmed, Ahmed M. Musa, Muna H. Hussein

Saudi Medical Journal

Visceral leishmaniasis VL, caused by Leishmania donovani is endemic over several parts of Sudan. The disease is fatal if not treated. Although sodium stibogluconate Pentostam, a pentavalent antimonial is not free from toxicity, it has been in use for treatment of VL for the last 50 years. Like other infectious diseases, neurological manifestations of VL and sodium stibogluconate have been documented. In this report, we present 2 cases of cerebellar ataxia most likely induced by Pentostam, and explain the probable cause.

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Vulvar Basal Cell Carcinoma Misdiagnosed For 4 Years, Iqbal A. Bukhari, Amina J. Khalid Jan 2006

Vulvar Basal Cell Carcinoma Misdiagnosed For 4 Years, Iqbal A. Bukhari, Amina J. Khalid

Saudi Medical Journal

Vulvar basal cell carcinoma is a rare cutaneous neoplasm occurring mainly in white postmenopausal females. It can be misdiagnosed due to its nonspecific physical appearance. Here, we report a 59-year-old white female who had vulvar basal cell carcinoma misdiagnosed for 4 years.

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Pregnancy Complicated By Superior Vena Cava Thrombosis And Pulmonary Embolism In A Patient With Behcet Disease And The Use Of Heparin For Treatment, Ahmet Kale, Levent Akyildiz, Nurten Akdeniz, Ebru Kale Jan 2006

Pregnancy Complicated By Superior Vena Cava Thrombosis And Pulmonary Embolism In A Patient With Behcet Disease And The Use Of Heparin For Treatment, Ahmet Kale, Levent Akyildiz, Nurten Akdeniz, Ebru Kale

Saudi Medical Journal

Behcet disease is a multisystemic vasculitis of unknown origin. Vascular involvement has been considered to result from systemic vasculitis, occurs in 5-10% of these patients. We report a 34-year-old pregnant woman complicated by superior vena cava thrombosis, and pulmonary embolism in a patient with Behcet disease.

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Rupture Of Spleen In A Mechanically Ventilated Patient With Falciparum Malaria Admitted With Pulmonary Edema, Wanis H. Ibrahim, Ahmed Kamha, Wisam Ghadban, Abdulatif Alkhal Jan 2006

Rupture Of Spleen In A Mechanically Ventilated Patient With Falciparum Malaria Admitted With Pulmonary Edema, Wanis H. Ibrahim, Ahmed Kamha, Wisam Ghadban, Abdulatif Alkhal

Saudi Medical Journal

Rupture of the spleen in malaria may constitute a diagnostic challenge to many clinicians particularly in non-endemic areas where experience with malaria is limited. Our aim is to increase the awareness among clinicians from non-endemic areas of serious malarial complications. We present a young American military man who was admitted to Hamad General Hospital and had 2 serious malarial complications, namely, acute pulmonary edema and rupture of the spleen. He was unusual compared with what was published previously in 4 main points: 1. The rupture of spleen occurred while the patient on mechanical ventilation and under the effect of sedation, …

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The Use Of Endovascular Stent-Grafts For The Treatment Of Common Carotid-Internal Jugular Fistula, Mohammed A. Bawazeer, Mohammed S. Al-Jared, Khalid A. Al-Brekeit, Wedad M. Al-Harbi Jan 2006

The Use Of Endovascular Stent-Grafts For The Treatment Of Common Carotid-Internal Jugular Fistula, Mohammed A. Bawazeer, Mohammed S. Al-Jared, Khalid A. Al-Brekeit, Wedad M. Al-Harbi

Saudi Medical Journal

We report a case of a fistula between the common carotid artery and the internal jugular vein due to a hemodialysis catheter insertion. We managed the fistula by the insertion of a covered-stent at the common carotid artery, and completely sealed the fistula without immediate complications. We present this case to highlight this new successful method of treatment.

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Acute Disseminated Encephalomyelitis In An Adult Patient . Magnetic Resonance And Diffusion-Weighted Imaging Findings, Mehmet H. Atalar Jan 2006

Acute Disseminated Encephalomyelitis In An Adult Patient . Magnetic Resonance And Diffusion-Weighted Imaging Findings, Mehmet H. Atalar

Saudi Medical Journal

Acute disseminated encephalomyelitis ADEM is an uncommon inflammatory disease of the central nervous system and can be defined strictly as scattered focal or multifocal disseminated inflammation of brain or spinal cord, or both. An ADEM usually reveals patchy demyelinated lesions with a high signal on T2-weighted sequences. Here, we report a case of a 39-year-old man with ADEM. Echo-planar trace diffusion magnetic resonance imaging revealed high signal intensity changes at the lesion sites on b=1000 s/mm2 images, initially suggesting restricted diffusion. On corresponding apparent diffusion coefficient ADC maps, however, the lesions have a high signal intensity and high ADC values, …

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Toxic Epidermal Necrolysis Due To Co-Trimoxazole, M. Taifour Suliman Jan 2006

Toxic Epidermal Necrolysis Due To Co-Trimoxazole, M. Taifour Suliman

Saudi Medical Journal

No abstract provided.

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Prilocaine Induced Methemoglobinemia, Sahender G. Aygencel, Emine Akinci, Gul Pamukcu Jan 2006

Prilocaine Induced Methemoglobinemia, Sahender G. Aygencel, Emine Akinci, Gul Pamukcu

Saudi Medical Journal

No abstract provided.

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Intraligamentary Solid-Cystic Neoplasia With Histomorphological Features Of Sclerosing Stromal Tumor, Zuhal Gucin Jan 2006

Intraligamentary Solid-Cystic Neoplasia With Histomorphological Features Of Sclerosing Stromal Tumor, Zuhal Gucin

Saudi Medical Journal

No abstract provided.

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The Factors Of Arteriovenous Fistula Failure In Hemodialysis Patient, Abdolhassan Talaiezadeh, Faramarz Paziar Jan 2006

The Factors Of Arteriovenous Fistula Failure In Hemodialysis Patient, Abdolhassan Talaiezadeh, Faramarz Paziar

Saudi Medical Journal

No abstract provided.

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Dark-Lumen Magnetic Resonance Colonography, Mathias Goyen, Waleed Ajaj, Thomas Lauenstein Jan 2006

Dark-Lumen Magnetic Resonance Colonography, Mathias Goyen, Waleed Ajaj, Thomas Lauenstein

Saudi Medical Journal

No abstract provided.

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The Use Of Etoricoxib In Patients With Bronchial Asthma Associated With Aspirin Sensitivity, Ibrahim K. Nahar, Abdulaziz T. Muqim, Bassmah I. Al-Qhouti, Adeeba A. Al-Herz, Diaa K. Shehab, Singh S. Uppal, Mousa E. Khadadah Jan 2006

The Use Of Etoricoxib In Patients With Bronchial Asthma Associated With Aspirin Sensitivity, Ibrahim K. Nahar, Abdulaziz T. Muqim, Bassmah I. Al-Qhouti, Adeeba A. Al-Herz, Diaa K. Shehab, Singh S. Uppal, Mousa E. Khadadah

Saudi Medical Journal

No abstract provided.

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Diagnostic Value Of Mr Imaging In Meniscal Tears Of The Knee, Khalilollah Nazem, Khashayar Jabalameli, Farhad Iranpour Jan 2006

Diagnostic Value Of Mr Imaging In Meniscal Tears Of The Knee, Khalilollah Nazem, Khashayar Jabalameli, Farhad Iranpour

Saudi Medical Journal

No abstract provided.

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Intramuscular Artemether In The Treat-Ment Of Uncomplicated Plasmodium Falciparum Malaria In Sudanese Patients, Ayda R. Mohammed-Ali, Musa M. Kheir, Ishag Adam Jan 2006

Intramuscular Artemether In The Treat-Ment Of Uncomplicated Plasmodium Falciparum Malaria In Sudanese Patients, Ayda R. Mohammed-Ali, Musa M. Kheir, Ishag Adam

Saudi Medical Journal

No abstract provided.

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Validity And Reliability Of The Turkish Version Of The Ferrans And Powers Quality Of Life Index Diabetes Version, Zeynep C. Ozer Jan 2006

Validity And Reliability Of The Turkish Version Of The Ferrans And Powers Quality Of Life Index Diabetes Version, Zeynep C. Ozer

Saudi Medical Journal

No abstract provided.

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Falls And Depression In The Elderly Population, Mustafa Afifi, Nezire Kose Jan 2006

Falls And Depression In The Elderly Population, Mustafa Afifi, Nezire Kose

Saudi Medical Journal

No abstract provided.

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The Diagonal Ear-Lobe Crease. As Sign Of Some Diseases, Damir Fabijanic, Dinko Miric, Mislav Radic, Meltem Bahcelioglu, Birol Demirel Jan 2006

The Diagonal Ear-Lobe Crease. As Sign Of Some Diseases, Damir Fabijanic, Dinko Miric, Mislav Radic, Meltem Bahcelioglu, Birol Demirel

Saudi Medical Journal

No abstract provided.

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