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2006

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Inhibition Of Inducible Nitric Oxide Synthase By A Mustard Gas Analog In Murine Macrophages, Min Qui, Victor M. Paromov, Hongsong Yang, Milton Smith, William L. Stone Nov 2006

Inhibition Of Inducible Nitric Oxide Synthase By A Mustard Gas Analog In Murine Macrophages, Min Qui, Victor M. Paromov, Hongsong Yang, Milton Smith, William L. Stone

ETSU Faculty Works

Background: 2-Chloroethyl ethyl sulphide (CEES) is a sulphur vesicating agent and an analogue of the chemical warfare agent 2,2′-dichlorodiethyl sulphide, or sulphur mustard gas (HD). Both CEES and HD are alkylating agents that influence cellular thiols and are highly toxic. In a previous publication, we reported that lipopolysaccharide (LPS) enhances the cytotoxicity of CEES in murine RAW264.7 macrophages. In the present investigation, we studied the influence of CEES on nitric oxide (NO) production in LPS stimulated RAW264.7 cells since NO signalling affects inflammation, cell death, and wound healing. Murine macrophages stimulated with LPS produce NO almost exclusively via inducible nitric …

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The Montclarion, November 30, 2006, The Montclarion Nov 2006

The Montclarion, November 30, 2006, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

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The East Texan, 2006-11-30, Texas A&M University-Commerce Nov 2006

The East Texan, 2006-11-30, Texas A&M University-Commerce

All Issues

Volume 91, number 13 of The East Texan, a student newspaper published at Texas A&M University-Commerce.

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The Influence Of Membrane Lipid Order On Cell Shape And Microvesiculation In Human Erythrocytes, Laurie Jackson Gonzalez Nov 2006

The Influence Of Membrane Lipid Order On Cell Shape And Microvesiculation In Human Erythrocytes, Laurie Jackson Gonzalez

Theses and Dissertations

Exposure of human erythrocytes to elevated intracellular calcium causes alterations in cell shape and stimulates shedding of the cell membrane in the form of microvesicles. We hypothesized that both the shape transition and microvesiculation are influenced by microscopic membrane physical properties such as lipid order. To test this hypothesis, membrane properties were manipulated by varying the experimental temperature, membrane cholesterol content, and the internal ionic environment. Changes in membrane order were assessed using steady-state fluorescence spectroscopy with an environment-sensitive probe, laurdan. Our observations led us to the following conclusions: 1) the modest temperature dependence of membrane structure observed with laurdan …

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Montana Kaimin, November 30, 2006, Students Of The University Of Montana, Missoula Nov 2006

Montana Kaimin, November 30, 2006, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

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Value-Based Coverage Policy In The United States And The United Kingdom: Different Paths To A Common Goal, Wilhelmine Miller Nov 2006

Value-Based Coverage Policy In The United States And The United Kingdom: Different Paths To A Common Goal, Wilhelmine Miller

National Health Policy Forum

This background paper traces the development within American health care of two interrelated trends and activities: an evidence-based approach to medical practice and the critical evaluation of new technologies with respect to their costs and effectiveness. Over the past 35 years each of these developments has increasingly shaped the coverage decisions of public and private health insurers, and their importance for coverage policy is certain to grow. The paper also contrasts the different approaches to such “evidence-” or “value-based” coverage policy in the mixed public and private U.S. health care enterprise with the approach taken in Great Britain’s single-payer National …

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A Long-Term Perspective On Drought In The Great Plains And West, Sherilyn C. Fritz Nov 2006

A Long-Term Perspective On Drought In The Great Plains And West, Sherilyn C. Fritz

Nebraska Water Center: Faculty Publications

Management of water resources requires an understanding of the full range of natural variability and its consequences. The weather record, which spans the last 100 years or so, provides a snapshot of the contemporary history of drought and its impacts, but this record is relatively short and is inadequate for understanding long-term trends or for evaluating the magnitude of human impacts. A variety of so-called paleoclimatic records - such as tree rings, lake sediments, and sand dunes - record the history of the environment and can be used to extend the record of climatic variation to older intervals of time. …

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Semiparametric Regression Of Multi-Dimensional Genetic Pathway Data: Least Squares Kernel Machines And Linear Mixed Models, Dawei Liu, Xihong Lin, Debashis Ghosh Nov 2006

Semiparametric Regression Of Multi-Dimensional Genetic Pathway Data: Least Squares Kernel Machines And Linear Mixed Models, Dawei Liu, Xihong Lin, Debashis Ghosh

The University of Michigan Department of Biostatistics Working Paper Series

SUMMARY. We consider a semiparametric regression model that relates a normal outcome to covariates and a genetic pathway, where the covariate effects are modeled parametrically and the pathway effect of multiple gene expressions is modeled parametrically or nonparametrically using least squares kernel machines (LSKMs). This unified framework allows a flexible function for the joint effect of multiple genes within a pathway by specifying a kernel function and allows for the possibility that each gene expression effect might be nonlinear and the genes within the same pathway are likely to interact with each other in a complicated way. This semiparametric model …

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Campus Chronicle, Jeremy Harmsen, Kelly Cheney, Malina Doke, Malin Cheney, Jeni Gieseke, Jesi Landwier, Megan Lyon, Alex Middleton, Aleah Christianson, Megan Harrison, Rick Farlow, Julie Roosa Nov 2006

Campus Chronicle, Jeremy Harmsen, Kelly Cheney, Malina Doke, Malin Cheney, Jeni Gieseke, Jesi Landwier, Megan Lyon, Alex Middleton, Aleah Christianson, Megan Harrison, Rick Farlow, Julie Roosa

Campus Chronicle

No abstract provided.

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Ke Alakai, Vol. 76, No. 13 (2006-11-29), Brigham Young University Hawaii Nov 2006

Ke Alakai, Vol. 76, No. 13 (2006-11-29), Brigham Young University Hawaii

Ke Alaka'i

No abstract provided.

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11-29-2006 Senior Biology Students Presenting Poster Presentations At Swosu, Southwestern Oklahoma State University Nov 2006

11-29-2006 Senior Biology Students Presenting Poster Presentations At Swosu, Southwestern Oklahoma State University

THE BARK ARCHIVE 2006

Seven senior biology students at Southwestern Oklahoma State University will present their term papers as poster presentations this Monday and Tuesday, December 4-5, on the Weatherford campus.

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The Lumberjack, November 29, 2006 Nov 2006

The Lumberjack, November 29, 2006

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

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Daily Eastern News: November 29, 2006, Eastern Illinois University Nov 2006

Daily Eastern News: November 29, 2006, Eastern Illinois University

November

No abstract provided.

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Central Florida Future, Vol. 39 No. 41, November 29, 2006 Nov 2006

Central Florida Future, Vol. 39 No. 41, November 29, 2006

Central Florida Future

No abstract provided.

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The Hilltop 11-29-2006, Hilltop Staff Nov 2006

The Hilltop 11-29-2006, Hilltop Staff

The Hilltop: 2000 - 2010

No abstract provided.

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Water Optimizer: A Tool For Decision Support And Policy Analysis, Derrel L. Martin, Ray Supalla Nov 2006

Water Optimizer: A Tool For Decision Support And Policy Analysis, Derrel L. Martin, Ray Supalla

Department of Agricultural Economics: Presentations, Working Papers, and Gray Literature

Water Optimizer is a tool for analyzing alternative water management strategies when the available water supply is limited. It can be used by producers to determine the profit maximizing crops to produce and the optimum amount of water to apply to each crop, given a particular water supply. It can also be used to evaluate the economic consequences of public policies which expand or reduce the amount of irrigation.

The Water Optimizer model can compute the profit maximizing strategy for producers located in any county in Nebraska where there is significant irrigation. This can be done for three different soil …

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The Bg News November 29, 2006, Bowling Green State University Nov 2006

The Bg News November 29, 2006, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. November 29, 2006. Volume 97-Issue 66.

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The Market Acceptance And Welfare Impacts Of ‘Terminator’ Technology, Marianna Khachaturyan, Amalia Yiannaka Nov 2006

The Market Acceptance And Welfare Impacts Of ‘Terminator’ Technology, Marianna Khachaturyan, Amalia Yiannaka

Cornhusker Economics

An Intellectual Property Rights (IPRs) system is effective when infringers can be identified, successfully sued for damages and deterred from further infringement. The effectiveness of IPRs in plant varieties is limited due to high detection costs of unauthorized use of seed that embodies intellectual property (e.g., genetically modified (GM) seed) and high enforcement costs. Seed companies have traditionally performed limited research and development (R&D) in self-pollinating plants mainly because seed saving limits their ability to recoup their investment.1

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The Diagnosis Of Adrenal Insufficiency In The Critically Ill Patient: Does It Really Matter?, Paul E. Marik Nov 2006

The Diagnosis Of Adrenal Insufficiency In The Critically Ill Patient: Does It Really Matter?, Paul E. Marik

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

No abstract provided.

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Factors Influencing Off-Flavor In Beef, Jennie Marie James Hodgen Nov 2006

Factors Influencing Off-Flavor In Beef, Jennie Marie James Hodgen

Department of Animal Science: Dissertations, Theses, and Student Research

Projects were conducted to increase knowledge of liver-like off-flavor origins in muscles from the beef chuck and round. Effects of cooking rate and holding time on off-flavor of various steaks from ten carcasses were determined. Off-flavor from these muscles was lowest when the steaks were cooked slowly (on a 149°C grill versus a 249°C grill) and when held for one hour prior to evaluation. The M. infraspinatus had the least off-flavor, and the M. vastus intermedius had the most intense off-flavor. These data suggest a carcass with one off-flavored muscle is likely to have other off-flavored muscles in the chuck …

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Montana Kaimin, November 29, 2006, Students Of The University Of Montana, Missoula Nov 2006

Montana Kaimin, November 29, 2006, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

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Semiparametric Regression Of Multi-Dimensional Genetic Pathway Data: Least Squares Kernel Machines And Linear Mixed Models, Dawei Liu, Xihong Lin, Debashis Ghosh Nov 2006

Semiparametric Regression Of Multi-Dimensional Genetic Pathway Data: Least Squares Kernel Machines And Linear Mixed Models, Dawei Liu, Xihong Lin, Debashis Ghosh

Harvard University Biostatistics Working Paper Series

No abstract provided.

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Rotunda - Vol 85, No 11 - Nov 28, 2006, Longwood University Nov 2006

Rotunda - Vol 85, No 11 - Nov 28, 2006, Longwood University

Rotunda

No abstract provided.

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November 28, 2006, Faculty Senate Nov 2006

November 28, 2006, Faculty Senate

Minutes

No abstract provided.

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Suppression Of Spontaneous Genome Rearrangements In Yeast Dna Helicase Mutants, Kristina H. Schmidt, Richard D. Kolodner Nov 2006

Suppression Of Spontaneous Genome Rearrangements In Yeast Dna Helicase Mutants, Kristina H. Schmidt, Richard D. Kolodner

Molecular Biosciences Faculty Publications

Saccharomyces cerevisiae mutants lacking two of the three DNA helicases Sgs1, Srs2, and Rrm3 exhibit slow growth that is suppressed by disrupting homologous recombination. Cells lacking Sgs1 and Rrm3 accumulate gross-chromosomal rearrangements (GCRs) that are suppressed by the DNA damage checkpoint and by homologous recombination-defective mutations. In contrast, rrm3, srs2, and srs2 rrm3 mutants have wild-type GCR rates. GCR types in helicase double mutants include telomere additions, translocations, and broken DNAs healed by a complex process of hairpin-mediated inversion. Spontaneous activation of the RadS3 checkpoint kinase in the rrm3 mutant depends on the Mec3/Rad24 DNA damage sensors and results from …

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Fabrication Of Gold Electrode Array Based On Co2 Laser Ablation, Wei Zhang, Jiang-Qun Xiao, Yong-Liang Zhou Nov 2006

Fabrication Of Gold Electrode Array Based On Co2 Laser Ablation, Wei Zhang, Jiang-Qun Xiao, Yong-Liang Zhou

Journal of Electrochemistry

A rapid process is described to produce single or multiple electrodes of any shape based on CO2 laser ablation for microfluidic chip.The method is as follow: coating a kind of material as sacrifice layer on a piece of glass with sputtered Cr and Au;designing the needed pattern on a computer;selecting proper parameters and ablating with CO2 laser;wiping of Au/Cr and sacrifice layer,and obtain electrodes at last.The microfluidic chip was gotten by reversely bonding with a piece of PDMS,and sealing around with PDMS prepolymer.The mask' effect is the main factor that influencing electrode quality.The width of electrodes could be …

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Deep Treatment Of Pulping Wastewater Using Three Phase Fluidized Bed Electrode Reactor, Dan Wu, Qi-Cai Shi, Ji-Ti Zhou, Bao-Jun Jia Nov 2006

Deep Treatment Of Pulping Wastewater Using Three Phase Fluidized Bed Electrode Reactor, Dan Wu, Qi-Cai Shi, Ji-Ti Zhou, Bao-Jun Jia

Journal of Electrochemistry

Treatment of pulping wastewater by using a novel electrochemical reactor,i.e.the three phase fluidized bed electrode,reactor were invesigated.The effects of air flow rate,applied voltage,pH value and FeSO4 concentration on electrolysis efficiency were investigated.It was clearly shown that the 20 V of voltage,0.3 m3·h-1 of air flow rate,1000 mg L-1 of FeSO4 concentration and pH≈2.5 were its best conditions.COD removal could be 70.1% under these conditions.

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Deposition Of Metallic Nanoparticles On Carbon Nanotubes Via A Fast Evaporation Process, Guoqiang Ren, Yangchuan Xing Nov 2006

Deposition Of Metallic Nanoparticles On Carbon Nanotubes Via A Fast Evaporation Process, Guoqiang Ren, Yangchuan Xing

Chemical and Biochemical Engineering Faculty Research & Creative Works

A new technique was developed for the deposition of colloidal metal nanoparticles on carbon nanotubes. It involves fast evaporation of a suspension containing sonochemically functionalized carbon nanotubes and colloidal nanoparticles. It was demonstrated that metallic nanoparticles with different sizes and concentrations can be deposited on the carbon nanotubes with only a few agglomerates. the technique does not seem to be limited by what the nanoparticles are, and therefore would be applicable to the deposition of other nanoparticles on carbon nanotubes. PtPd and CoPt3 alloy nanoparticles were used to demonstrate the deposition process. It was found that the surfactants used to …

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Current And Historical Aquatic Food Webs Of The Middle Rio Grande, Nm, Melanie S. Edwards Nov 2006

Current And Historical Aquatic Food Webs Of The Middle Rio Grande, Nm, Melanie S. Edwards

Biology ETDs

The Rio Grande has been identified as one of the most endangered rivers in the United States by American Rivers. Biologically, the consequences of the massive anthropogenic alterations of this river have been substantial. The overall aim of this study was to characterize the ecological implications of these alterations in the aquatic food web of the middle Rio Grande (MRG) of New Mexico. Our approach was to analyze the stable isotope composition of current food web components and of historical museum preserved fish specimens. After determining that we could use stable isotope analyses of historical museum preserved fish specimens (chapter …

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Volume 44, Number 28: November 28, 2006, University Of North Dakota Nov 2006

Volume 44, Number 28: November 28, 2006, University Of North Dakota

University Letter Archive

No abstract provided.

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