Digital Commons Network^™

Immunologic Memory To Polysaccharide Antigens, Tetyana V. Obukhanych

Student Theses and Dissertations

Immunologic memory is the ability of the immune system to generate an enhanced antibody response against previously encountered antigens. The clonal selection theory of acquired immunity attributes immunologic memory to the formation of an expanded compartment of quiescent antigen-specific memory B cells that are capable of rapid activation upon secondary antigen encounter. Whereas protein antigens are known to elicit memory B cells, it is not known whether polysaccharide antigens do. Here we report that polysaccharide antigens elicit memory B cells that are phenotypically distinct from those elicited by protein antigens. We show that antigen affinity of the B cell receptor …

Medicine@Yale March/April 2006 Volume 2, Issue 2, Yale School Of Medicine Office Of Communications

Medicine@Yale - development newsletter

Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.

Amino Acid Sequence Determination Of Protein Biomarkers Of Campylobacter Upsaliensis And C. Helveticus By “Composite” Sequence Proteomic Analysis, Clifton K. Fagerquist

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

We have identified the protein biomarkers observed in the matrix-assisted laser desorption/ionization time-of-flight mass spectra (MALDI-TOF-MS) of cell lysates of five strains of Campylobacter upsaliensis and one strain of C. helveticus by “bottom-up” proteomic techniques. Only one C. upsaliensis strain had previously been genomically sequenced. The significant findings are as follows: (1) The protein biomarkers identified were: 10 kD chaperonin, protein of unknown function (DUF465), phnA protein, probable periplasmic protein, D-methionine-binding lipoprotein MetQ, cytochrome c family protein, DNA-binding protein HU, thioredoxin, asparigenase family protein, helix-turn-helix domain protein, as well as several ribosomal and conserved hypothetical proteins. (2) Amino acid substitutions …

Norming The Mad-As To The Staxi-2 In A Hypertensive Population , Robert J. Liskowicz

PCOM Psychology Dissertations

Development of the Mahan and DiTomasso Anger Scale (MAD-AS) provided a valid and preferable alternative to the existing, lengthy tests of anger which are currently available. However, the MAD-AS was developed on a clinical, psychiatric population, and only one other study to date has attempted to utilize this test on a normal population. With strong links between anger and adverse physical health, and an ongoing controversy over whether anger expression versus anger suppression contributes more highly to the development and maintenance of hypertension, a prospective study measuring anger with established hypertensive subjects is being proposed utilizing both the MAD-AS, as …

Rrh Library Newsletter, January 2006, Libraries At Rochester Regional Health

Rochester Regional Health authored publications and proceedings

Newsletter sections include: Pandemic

Medical Education Digest, Vol. 8 No. 1 (January/February 2006), Nova Southeastern University

Medical Education Digest

No abstract provided.

F1rst Look 2006, Nova Southeastern University

First Look

No abstract provided.

Health Professions Division Catalog 2006-2007, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Evaluation Of A Cancer Awareness Campaign: Experience With A Selected Population In Karachi, Tazeen S. Ali, Sanah Baig

School of Nursing & Midwifery

The incidence and prevalence of cancer is rapidly increasing in both developed and developing countries. The most common cancers reported in Pakistan are breast and cervical cancers in females, and lung and oral cancers in males. Public awareness of cancer can play a vital role in its prevention, early diagnosis and treatment. A pilot survey conducted by the Cancer Support Group (CSG) of Aga Khan University Hospital from 2001 till 2004 to gauge the public awareness of cancer in Pakistan revealed that people were afraid of cancer and had little knowledge about its prevention and early detection. The survey also …

Hiv-1 Subtype A Infection In A Community Of Intravenous Drug Users In Pakistan, Saeed Khan, Mohammad A. Rai, Mohammad R. Khanani, Muhammad N. Khan, Syed H. Ali

Department of Biological & Biomedical Sciences

Background: Data on the subtypes of HIV in a population help in predicting the potential foci of epidemic, tracking the routes of infection and following the patterns of the virus' genetic divergence. Globally, the most prevalent HIV infection is the HIV-1 subtype C. In Asia, predominant subtypes of HIV-1 are B, C, and CRF-01AE. During the last few years, HIV prevalence in Pakistan has taken the form of a concentrated epidemic in at least two high risk groups, namely, Intravenous Drug Users (IDUs) and Male Sex Workers (MSWs). Factors that have facilitated the proliferation of HIV infection include transmission through …

Responses To Terrorism Scenarios: Event Features, Individual Characteristics, And Subjective Evaluations, Clinton Michael Jenkin

Doctoral Dissertations

The extensive research into responses to terrorism has focused on the effects of individual characteristics on reactions to past terrorism events. This literature has largely omitted two issues: the impact of terrorism event features, and reactions to possible future terrorism events. The first purpose of this dissertation was to account for the effects of event features as well as subjective evaluations on responses to terrorism events. The second purpose of this dissertation was to compare reactions to past and future terrorism scenarios.

A series of actual and hypothetical written scenarios were presented to undergraduate psychology students, and various responses measured. …

Relief For Wanderers: The Transient Service In Kansas, 1933-35, Peter Fearon

Great Plains Quarterly (through 2013)

Located at the crossroads of America, Kansas had long experience of interstate migrants. For many decades armies of workers had entered the state to pursue the harvest of a number of crops, or to pick up whatever work was available on their way west in pursuit of a more rewarding life. The U.S. population was highly mobile and migration played an essential role in a vigorously expanding economy. Ailing transients, especially tubercular cases, had as their destination the pure, dry air of the Southwest. To these we can add indeterminate numbers of seasonal workers, ex-veterans, homeless boys, peddlers, beggars, and …

A Study Of Machine Learning Performance In The Prediction Of Juvenile Diabetes From Clinical Test Results, Shibendra Pobi

USF Tampa Graduate Theses and Dissertations

Two approaches to building models for prediction of the onset of Type 1 diabetes mellitus in juvenile subjects were examined. A set of tests performed immediately before diagnosis was used to build classifiers to predict whether the subject would be diagnosed with juvenile diabetes. A modified training set consisting of differences between test results taken at different times was also used to build classifiers to predict whether a subject would be diagnosed with juvenile diabetes. Neural networks were compared with decision trees and ensembles of both types of classifiers. Support Vector Machines were also tested on this dataset. The highest …

Abstracts Of Presentations, Colby College

Undergraduate Research Symposium (UGRS)

No abstract provided.

Upper Extremities Function In Patients Undergoing Hemodialysis Treatment, Bilge B. Calik, Nesrin Yagci, Ugur Cavlak

Neurosciences

OBJECTIVE: To determine the effects of hemodialysis treatment on upper extremities functional ability. METHODS: This study was carried out from June 2003 to March 2004 at Pamukkale University School of Physical Therapy, Denizli, Turkey. One hundred patients with chronic renal failure (CRF) undergoing hemodialysis treatment for at least 2 months participated in the study, and were compared with a control group (N=40 healthy subjects). The 100 patients were divided into 4 groups according to the length of hemodialysis duration: 19 patients dialyzing for less than one year (Group 1); 42 patients dialyzing for 1-4 years (Group 2); 21 patients dialyzing …

Exploring Current Practices In Pediatric Arv Rollout And Integration With Early Childhood Programs In South Africa: A Rapid Situation Analysis, Desiree Michaels, Brian Eley, Lewis Ndhlovu, Naomi Rutenberg

HIV and AIDS

This Horizons program report describes the status of pediatric HIV treatment in selected sites in South Africa, identifies gaps in service delivery, and proposes recommendations for strengthening services and expanding children’s access to treatment. The study provides much needed information on critical issues of pediatric HIV care, especially regarding health service and contextual issues surrounding the expansion of access to treatment for HIV-infected children, and key factors that facilitate sustainability of treatment by young children. The aims of the study were to identify successful program strategies in pediatric HIV treatment in South Africa and to determine priority knowledge gaps to …

Literature Cited, Studies In Avian Biology

Studies in Avian Biology

No abstract provided.

Literature Cited, Studies In Avian Biology

Studies in Avian Biology

No abstract provided.

Informed Consent In Hiv Prevention Trials: Report Of An International Workshop, C. Elizabeth Mcgrory, Barbara Friedland, Cynthia Woodsong, Kathleen M. Macqueen

HIV and AIDS

This report summarizes key themes and issues on informed consent in HIV prevention trials as part of an international workshop co-hosted by Population Council and Family Health International in May 2005.

A Group M Consensus Envelope Glycoprotein Induces Antibodies That Neutralize Subsets Of Subtype B And C Hiv-1 Primary Viruses, Hua-Xin Lin, Laura L. Sutherland, Shi-Mao Xia, Mary E. Brock, Richard M. Scearce, Stacie Vanleeuwen, S. Munir Alam, Mildred Mcadams, Eric A. Weaver, Zenaido T. Camacho, Ben-Jiang Ma, Yingying Li, Julie M. Decker, Gary J. Nabel, David C. Montefiori, Beatrice H. Hahn, Bette T. Korber, Feng Gao, Barton F. Haynes

Nebraska Center for Virology: Faculty Publications

HIV-1 subtype C is the most common HIV-1 group M subtype in Africa and many parts of Asia. However, to date HIV-1 vaccine candidate immunogens have not induced potent and broadly neutralizing antibodies against subtype C primary isolates. We have used a centralized gene strategy to address HIV-1 diversity, and generated a group M consensus envelope gene with shortened consensus variable loops (CON-S) for comparative studies with wildtype (WT) Env immunogens. Our results indicate that the consensus HIV-1 group M CON-S Env elicited cross-subtype neutralizing antibodies of similar or greater breadth and titer than the WT Envs tested, indicating the …

When And Why Does What Belong To Whom - A Proposed Model For The International Protection Of Human Donors Of Biological Material, Melanie Baird

Canada-United States Law Journal

No abstract provided.

Board Of Regents Meeting Materials, March 21, 2006, Eastern Michigan University

Board of Regents Meeting Materials

No abstract provided.

Human Rights In Cuba, Susan Kemp

Human Rights & Human Welfare

In 1959, Fidel Castro established a Cuban socialist state closely aligned with the Soviet Union. The Soviet Union's collapse brought an end to Soviet economic support which, combined with the U.S. embargo, created an economic crisis in the early 1990s. The Cuban government's instability and desire to maintain control overrides the individual rights of its citizens. These events are the background for the lack of fundamental human rights in Cuba today.

Guantanamo And U.S. Law, Joseph C. Sweeney

Fordham International Law Journal

This Article deals with the United States' presence at Guantanamo Bay, Cuba, the domestic and international law issues that have arisen, and the nature of the jurisdiction exercised there by the United States. It does not deal with the operation of the prison facility. Guantanamo Bay is near the eastern end of Cuba, 628 miles (1000 km) from the capital, Havana. It is a deep-water harbor, protected by hills from the extremes of Caribbean weather; but it has an unhealthy tropical climate. The forty-five square miles of the Guantanamo Naval Base have been occupied by the United States since the …

Bioterrorism Or Avian Influenza: California, The Model State Emergency Health Powers Act, And Protecting Civil Liberties During A Public Health Emergency, N. Pieter M. O'Leary

California Western Law Review

No abstract provided.

An Investigation Into The Effects Of Social Network Strength And Stress Level On Cardiovascular Responses In Colleges Students, Amy R. Levitt

Modern Psychological Studies

The present study investigated the effects of strength of social network on physiological stress during a cognitive task. Participants were randomly assigned to a timed or untimed word search task. The dependent variables were heart rate and participants' perceptions of the difficulty of their word search task. Participants in the high stress condition reported performing significantly worse on the word search task than those in the low stress condition. Participants perceived the task to be less difficult when in the high social network group as compared to the low social network group. While there were no significant findings for the …

Cutaneous And Presumed Visceral Leishmaniasis In A Soldier Deployed To Afghanistan, James P. Woodrow, Joshua D. Hartzell, Jim Czarnik, David Brett-Major, Glenn Wortmann

Journal Articles: Epidemiology

Leishmaniasis has been frequently diagnosed in US military personnel returning from duty in Southwest Asia. The majority of cases have demonstrated cutaneous disease, although a few cases of visceral disease have been documented. We present the case of an immunocompetent, HIV-negative, US Army soldier who suffered both visceral and cutaneous manifestations of leishmaniasis after returning from deployment in Afghanistan. Overlap of cutaneous and visceral involvement is rare and has not been reported in our cohort. Latent Plasmodium vivax infection may have been an exacerbating cofactor. We discuss this case and present a review of the literature.

Laboratory Diagnosis Of Tuberculosis In Primary Care, David Brett-Major, Thomas E. Walsh

Journal Articles: Epidemiology

No abstract provided.

The Science Of Prevention Strategies, Rachel Abrishami, Jeffery A. Goad

Pharmacy Faculty Articles and Research

"From newborn screening for Phenylkentonurea (PKU) and the birth dose of Hepatitis B vaccine to prostate and breast cancer screening and pneumococcal immunization for older adults, the science of health maintenance is multi-tiered and spans the lifetime of an individual. Primary, secondary, and tertiary prevention strategies are used in concert with each other to enable healthcare professionals and their patients to sustain and improve the quality of life."

Otterbein Towers Winter 2006, Otterbein Towers

Towers Magazine

Features: Students Sleep Out for the Homeless; In the Wake of Katrina; Playing for Peace; Regulars: College News: Otterbein Holds Pow Wow; Spirits Fly on Campus! The House that Moe Built; Service Group Finds New Home; Noted Author and Physicist Visits; Otterbein Fully Accredited; Otterbein Selected for Global Learning; Common Book Author Visits; Otterbein Gets a New Logo; Classnotes; Milestones; Investing in Otterbein; The “O” Club; Alumni Notes, etc.