Digital Commons Network^™

Ils En Ont Parle, Mary Elizabeth Roe

Honors Theses

The Dreyfus Affair, which began in 1894. was not only a political clash. It also engulfed the social and cultural worlds of France during the nineteenth and twentieth centuries. From the highest politician to the average French citizen, people from ever}' background were aware of the Dreyfus Affair and its implications for France. This Affair divided the people of France in every way possible and impressed itself upon every walk of French life for over a decade. With the aid of modem mass media, the Affair spread to every corner of France. By causing divisions in its cultural, social, and …

Ecocritism And The Renaissance: A Study In Shakespeare And More, Melissa Levert Smith

Honors Theses

This study draws on ideas from the emerging field of literary criticism known as ecocriticism and extends its basic assumptions back to the Renaissance works of Thomas More and William Shakespeare. The research therefore includes primary Renaissance texts, current ecocritical works, and selections from the twentieth-century criticism from which ecocriticism developed. I investigate in detail More’s Utopia and Shakespeare’s A Midsummer Night’s Dream and King Lear. The study takes into account the disparity between Renaissance attitudes towards the environment and current concerns about pollution and scarcity of resources, but I suggest that the questions asked by ecocritical scholars today, when …

Cotton And Compromise: Charles Pinckney And The Political Unification Of South Carolina 1788-1808, Hunter Glenn Upchurch

Honors Theses

This project surveys the life and times of South Carolinian Charles Pinckney after he participated in the Constitutional Convention of 1787. My objective was to discern how Pinckney’s political career both mirrored and contributed to South Carolina’s gradual shift away from Federalism towards Jeffersonian-Republicanism, as the western “Up-Country” region slowly took power from the more traditional, coastal “Low- Country.” To achieve this goal, I examined hundreds of pages of primary sources, including Pinckney’s extant speeches, his published articles or pamphlets, and many of his personal letters. To augment my factual and historiographical knowledge of the early national period of United …

Improving Group Work: Voices Of Students, Brian K. Payne, Elizabeth Monk-Turner, Donald Smith, Melvina Sumter

Sociology & Criminal Justice Faculty Publications

Group work is increasingly being used in a variety of college courses. A number of strengths have driven the increase in the use of this form of collaborative learning. Still, a number of problems potentially limit the use of group projects. In this study, we report on research in which we examined how students recommended changing group projects. Results are categorized into student-centered themes and faculty-centered themes. Implications are provided.

Isolation And Characterization Of Toxin A-Negative, Toxin B-Positive Clostridium Difficile In Dublin, Ireland, Denise Drudy, N. Harnedy, S. Fanning, R. O’Mahony, L. Kyne

Articles

Clostridium difficile is a major cause of infectious diarrhoea in hospitalised patients. Most pathogenic C. difficile strains produce two toxins, A and B; however, clinically relevant toxin A-negative, toxin Bpositive (A– B+ ) strains of C. difficile that cause diarrhoea and colitis in humans have been isolated worldwide. The aims of this study were to isolate and characterise A– B+ strains from two university hospitals in Dublin, Ireland. Samples positive for C. difficile were identified daily by review of ELISA results and were cultured on selective media. Following culture, toxin-specific immunoassays, IMR-90 cytotoxicity assays and PCR were used to analyse …

High-Level Resistance To Moxifloxacin And Gatifloxacin Associated With A Novel Mutation In Gyrb In Toxin-A-Negative, Toxin-B-Positive Clostridium Difficile, Denise Drudy, T. Quinn, R. O'Mahony, L. Kyne, P. O'Gaora, S. Fanning

Articles

OBJECTIVES:

To determine the mechanism of high-level resistance to fluoroquinolone antimicrobials in toxin-A-negative, toxin-B-positive (A- B+) Clostridium difficile isolates.

METHODS:

Following culture 16-23S PCR ribotyping was used to determine genomic relationships between A- B+ C. difficile isolates. Antimicrobial susceptibilities were determined using Etests in the presence and absence of the efflux pump inhibitors reserpine (20 microg/mL), L-phenylalanine-L-arginine-beta-naphthylamide (PAbetaN; 20 microg/mL) and verapamil (100 microg/mL). Genomic regions including the quinolone-resistance-determining-region (QRDR) of gyrA and gyrB were amplified and characterized.

RESULTS:

PCR ribotyping profiles identified one major cluster of A- B+ C. difficile, universally resistant to the fluoroquinolones tested (ofloxacin, ciprofloxacin, levofloxacin, …

Characterization Of A Collection Of Enterobacter Sakazakii Isolates From Environmental And Food Sources., Denise Drudy, Michele O'Rourke, Mary Murphy, Niall Mullane, Rebecca O'Mahony, Lorainne Kelly, Matthias Fischer, Suhad Sanjag, Pauline Shannon, Patrick Wall, Micheál O'Mahony, Paul Whyte, Séamus Fanning

Articles

No abstract provided.

Comparative Phylogenomics Of Clostridium Difficile Reveals Clade Specificity And Microevolution Of Hypervirulent Strains., Denise Drudy

Articles

No abstract provided.

Chapter Four: A New Storm Gathers

Rosalie Rendu

No abstract provided.

Chapter Eight: Expansion Of The Works Of Rue De L'Épée-De-Bois

Rosalie Rendu

No abstract provided.

Chapter Six: At The Service Of The Poor Of The Mouffetard District

Rosalie Rendu

No abstract provided.

Chapter Thirteen: Limitations On Sister Rosalie's Apostolic Activity

Rosalie Rendu

No abstract provided.

Chapter Ten: Sister Rosalie's Network Of Charity

Rosalie Rendu

No abstract provided.

Mapping Concepts In Medical Error Taxonomies, Min Zhu, Yong Huang, Yang Gong, Juliana J. Brixey, Jiajie Zhang, James P. Turley

Faculty, Staff and Student Publications

No abstract provided.

Construction Of Improved Temperature-Sensitive And Mobilizable Vectors And Their Use For Constructing Mutations In The Adhesin-Encoding Acm Gene Of Poorly Transformable Clinical Enterococcus Faecium Strains, Sreedhar R Nallapareddy, Kavindra V Singh, Barbara E Murray

Faculty, Staff and Student Publications

Inactivation by allelic exchange in clinical isolates of the emerging nosocomial pathogen Enterococcus faecium has been hindered by lack of efficient tools, and, in this study, transformation of clinical isolates was found to be particularly problematic. For this reason, a vector for allelic replacement (pTEX5500ts) was constructed that includes (i) the pWV01-based gram-positive repAts replication region, which is known to confer a high degree of temperature intolerance, (ii) Escherichia coli oriR from pUC18, (iii) two extended multiple-cloning sites located upstream and downstream of one of the marker genes for efficient cloning of flanking regions for double-crossover mutagenesis, (iv) transcriptional terminator …

Dose-Response Characteristics Of Methylphenidate On Locomotor Behavior And On Sensory Evoked Potentials Recorded From The Vta, Nac, And Pfc In Freely Behaving Rats, Pamela B Yang, Alan C Swann, Nachum Dafny

Faculty, Staff and Student Publications

BACKGROUND: Methylphenidate (MPD) is a psychostimulant commonly prescribed for attention deficit/hyperactivity disorder. The mode of action of the brain circuitry responsible for initiating the animals' behavior in response to psychostimulants is not well understood. There is some evidence that psychostimulants activate the ventral tegmental area (VTA), nucleus accumbens (NAc), and prefrontal cortex (PFC).

METHODS: The present study was designed to investigate the acute dose-response of MPD (0.6, 2.5, and 10.0 mg/kg) on locomotor behavior and sensory evoked potentials recorded from the VTA, NAc, and PFC in freely behaving rats previously implanted with permanent electrodes. For locomotor behavior, adult male Wistar-Kyoto …

Chronic Exposure To Mdma (Ecstasy) Elicits Behavioral Sensitization In Rats But Fails To Induce Cross-Sensitization To Other Psychostimulants, Gunjan M Modi, Pamela B Yang, Alan C Swann, Nachum Dafny

Faculty, Staff and Student Publications

BACKGROUND: The recreational use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) among adolescents and young adults has become increasingly prevalent in recent years. While evidence suggests that the long-term consequences of MDMA use include neurodegeneration to serotonergic and, possibly, dopaminergic pathways, little is known about susceptibility, such as behavioral sensitization, to MDMA.

METHODS: The objectives of this study were to examine the dose-response characteristics of acute and chronic MDMA administration in rats and to determine whether MDMA elicits behavioral sensitization and whether it cross-sensitizes with amphetamine and methylphenidate. Adult male Sprague-Dawley rats were randomly divided into three MDMA dosage groups (2.5 mg/kg, 5.0 …

Second Step: A Violence Prevention Curriculum, Pam Dell Fitzgerald, Leihua Van Schoiack Edstrom

Faculty Publications - Doctor of Psychology (PsyD) Program

Second Step: A Violence Prevention Curriculum is a school-based program developed to reduce and prevent aggressive behavior. Three separate age-appropriate curricula are available for preschool through middle school classrooms (preschool/kindergarten level, elementary level, and middle school/junior high level). The curricula are designed to be teacher-friendly and convenient for classroom use. Their primary purpose is to decrease children's aggressive behaviors by helping children develop habits of prosocial behavior and thought. The curricula employ evidence-based strategies that are built on a broad and solid foundation of research. Each of the three curricula have been evaluated and found to reduce aggression and increase …

The Quest For A Biblical Trinity: Ellen White's "Heavenly Trio" Compared To The Traditional Doctrine, Jerry Moon

Journal of the Adventist Theological Society

No abstract provided.

Sanctuary Principles For The Successful Church Community, Roy E. Gane

Journal of the Adventist Theological Society

No abstract provided.

China's Acquisitions Abroad - Global Ambitions, Domestic Effects, Nicholas C. Howson

Articles

In the past year or so, the world has observed with seeming trepidation what appears to be a new phenomenon-China's "stepping out" into the world economy. The move, labeled the "Going Out Strategy" by Chinese policy makers, sees China acting in the world not just as a trader of commodities and raw materials, or the provider of inexpensively-produced consumer goods for every corner of the globe, but as a driven and sophisticated acquirer of foreign assets and the equity interests in the legal entities that control such assets. The New Yorker magazine, ever topical and appropriately humorous, highlighted this attention …

The (Legal) Pains Of Vioxx: Why Product Liability Can Make Products More Dangerous, Omri Ben-Shahar

Articles

Comparing the experience of Vioxx and Celebrex leads Omri Ben-Shahar to think that stiff product liability has the perverse effect of inducing manufacturers of defective products to leave these products on the market, rather than withdraw them.

Justice In The Balance: An Evaluation Of One Clinic's Ability To Harmonize Teaching Practical Skills, Ethics And Professionalism With A Social Justice Mission, Lauren Carasik

Faculty Scholarship

A number of developments have firmly established the role of clinics in legal education, allowing law school clinicians greater latitude in designing programs consistent with law school curricular values and priorities. Consequently, current law school clinical offerings are comprised of richly varied structures and goals. A myriad of goals fall under the general rubric of clinical legal education. Among the most widely cited goals are providing practical skills training in a real world context, instilling a public interest ethos in students, advancing social justice, encouraging the critique of the law and legal institutions, inculcating high standards of ethics and professionalism …

A Patient-Centered Approach To Health Care Fraud Recovery, Joan H. Krause

Faculty Publications

No abstract provided.

Impact On Washington State's Budget Of Allowing Same-Sex Couples To Marry, M.V. Lee Badgett, R. Bradley Sears, Elizabeth Kukura, Holning S. Lau, The Williams Institute

Faculty Publications

No abstract provided.

The Enumeration Of Rights: "Let Me Count The Ways", John V. Orth

Faculty Publications

No abstract provided.

The Market Participant Doctrine And The Clear Statement Rule, David S. Bogen

Seattle University Law Review

When the state acts as a market regulator, the dormant Commerce Clause invalidates discriminatory regulation without the need for an order against the state. The courts simply refuse to enforce the state law on the ground that it is unconstitutional. When the state acts as a market participant, however, the court would have to direct its order against the state or its officials to negate the discrimination. This produces a direct confrontation with the state, the same kind of confrontation the clear statement rule was designed to avoid. Part II of this article examines the theory of the dormant Commerce …

Circular 230 Opinion Standards, Legal Ethics And First Amendment Limitations On The Regulation Of Professional Speech By Lawyers, David T. Moldenhauer

Seattle University Law Review

Part II of this Article discusses the background, scope, and requirements of the Circular 230 rules. Part III discusses the ethical rules applicable to tax opinions, compares these rules to the Circular 230 opinion standards, and concludes that the Circular 230 standards impose substantially greater requirements on practitioners than, and in certain respects conflict with, the ethical rules. Part IV discusses First Amendment case law and commentary regarding professional speech, and proposes that professional speech regulations be analyzed by a model that defines permissible regulation of professional speech by reference to the role of the profession in society and accepted …

The Value Of Government Tort Liability: Washington State's Journey From Immunity To Accountability, Debra L. Stephens, Bryan P. Harnetiaux

Seattle University Law Review

Part I of this Article traces Washington's history with the common law doctrine of government immunity from tort liability. It also identifies other distinct common law immunities protecting executive, legislative, and judicial functions-immunities that lay dormant during the reign of sovereign immunity. Part II discusses the legislature's broad waiver of sovereign immunity in 1961 and the legislature's subsequent reaffirmation of the waiver. It also notes isolated instances in which the legislature has partially restored immunity or otherwise limited tort liability. Part III addresses the development of case law interpreting the scope of government tort liability in light of the legislative …

Learning To Live And Living To Learn: An Exploration Of Human Relations In The Classroom, Stephanie Lynn Orth

Honors Program Theses

Teaching human relations in schools is the only way to insure egocentrism is left for altruism. That is, to insure that people start to think of others instead of only themselves (Lane, 109). Many people have lost any obligation to serve anyone beyond themselves (Damon, 38). Students feel less responsible for their actions today, than in the past. Teaching students a sense of altruism is the only way to ensure that both new and current world knowledge of facts, concepts, and inventions are used to relieve suffering, as President Truman described, and not to cause it (Lane, 89).

Therefore, human …