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2006

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The Effect Of Adding Drag-Reducing Polymers To Resuscitation Fluid During Hemorrhagic Shock On Skeletal Muscle Microcirculation, Geoffrey C. Alexander Jan 2006

The Effect Of Adding Drag-Reducing Polymers To Resuscitation Fluid During Hemorrhagic Shock On Skeletal Muscle Microcirculation, Geoffrey C. Alexander

Theses and Dissertations

Previous studies have shown an increase in survival when a minute amount of drag-reducing polymers were added to a resuscitation fluid. The purpose of this investigation was to examine the effect of adding a minute amount of the drag-reducing polymer polyethylene glycol to a resuscitation fluid, on the microcirculation of skeletal muscle during a volume-controlled hemorrhage model. The spinotrapezius muscle in twelve male Sprague Dawley rats was exteriorized for microvascular measurements of the arterioles. The diameters of the three levels of arterioles, interstitial fluid PO2, and RBC velocity in the feed arteriole were measured. Flow in the feed arteriole was …

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The Ins And Outs Of School Provider Literature: A Multi-Year Content Analysis On Lgbt Youth, Caitlin Conor Ryan Jan 2006

The Ins And Outs Of School Provider Literature: A Multi-Year Content Analysis On Lgbt Youth, Caitlin Conor Ryan

Theses and Dissertations

This study is based on a content analysis of two primary sources: 1) literature published on lesbian, gay, bisexual and transgender (LGBT) youth in professional journals for school providers (school counselors, nurses, psychologists and social workers) over more than a 30-year period; and 2) materials developed for school providers on LGBT youth by states with laws, regulations and professional policies related to sexual orientation and/or gender identity in schools. Fifteen professional journals were identified that serve as primary and secondary journals for school providers. A total of 41 articles were published in these journals on LGBT youth between 1937 and …

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Medications That Should Not Be Crushed, K. Shaver, Joseph A. Woelfel Jan 2006

Medications That Should Not Be Crushed, K. Shaver, Joseph A. Woelfel

School of Pharmacy Faculty Articles

No abstract provided.

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Over-The-Counter Supplements For Cholesterol Lowering, K. M. Shields, Joseph A. Woelfel Jan 2006

Over-The-Counter Supplements For Cholesterol Lowering, K. M. Shields, Joseph A. Woelfel

School of Pharmacy Faculty Articles

No abstract provided.

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Topical Treatment Of Chronic Wounds, Joseph A. Woelfel Jan 2006

Topical Treatment Of Chronic Wounds, Joseph A. Woelfel

School of Pharmacy Faculty Articles

No abstract provided.

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Intercellular Spreading Of Porphyromonas Gingivalis Infection In Primary Gingival Epithelial Cells, Özlem Yilmaz, Philippe Verbeke, Richard J. Lamont, David M. Ojcius Jan 2006

Intercellular Spreading Of Porphyromonas Gingivalis Infection In Primary Gingival Epithelial Cells, Özlem Yilmaz, Philippe Verbeke, Richard J. Lamont, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Porphyromonas gingivalis, an important periodontal pathogen, is an effective colonizer of oral tissues. The organism successfully invades, multiplies in, and survives for extended periods in primary gingival epithelial cells (GECs). It is unknown whether P. gingivalis resides in the cytoplasm of infected cells throughout the infection or can spread to adjacent cells over time. We developed a technique based on flow cytofluorometry and fluorescence microscopy to study propagation of the organism at different stages of infection of GECs. Results showed that P. gingivalis spreads cell to cell and that the amount of spreading increases gradually over time. There was a …

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Bs News Jan 2006

Bs News

Building Services Engineering

No abstract provided.

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Angiotensin Ii And Aldosterone Increase With Fasting In Breeding Adult Male Northern Elephant Seals (Mirounga Angustirostris), Rudy M. Ortiz, Daniel E. E. Crocker, Dorian S. Houser, Paul M. Webb Jan 2006

Angiotensin Ii And Aldosterone Increase With Fasting In Breeding Adult Male Northern Elephant Seals (Mirounga Angustirostris), Rudy M. Ortiz, Daniel E. E. Crocker, Dorian S. Houser, Paul M. Webb

Arts & Sciences Faculty Publications

The renin‐angiotensin‐aldosterone system (RAAS) appears to contribute significantly to osmoregulation of fasting northern elephant seal (Mirounga angustirostris) pups; however, RAAS has not been characterized in fasting adult seals. Therefore, this study examined the contribution of RAAS to water turnover rates in fasting adult male northern elephant seals. Blood samples were obtained twice during their breeding fast at an interval of 6.5 wk, and water efflux rate was estimated by isotopic dilution during the same period. Serum electrolytes (Na+, K+, Cl−) and osmolality were unaltered between the two sampling periods, indicating ionic and …

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Sinking Poor Decision-Making With Best Practices: A Case Study Of Artificial Reef Decision-Making In The Florida Keys, Thomas Wayne Williams Jan 2006

Sinking Poor Decision-Making With Best Practices: A Case Study Of Artificial Reef Decision-Making In The Florida Keys, Thomas Wayne Williams

Theses and Dissertations

The natural reefs of the world are experiencing higher use and pressures, resulting in anthropogenic impacts that are deteriorating many coral stands and creating poor water quality. The Florida Keys rely primarily on the reef system that surrounds the archipelago for their socioeconomic health and successful future. The Florida Keys shares the symbiotic relationship of the terrestrial and marine realms with many other states and countries and the experience of higher demand on the resource. Artificial reefs could provide a substitute to the natural reefs for commercial and recreational users. An increased demand for derelict vessels of the U.S. Navy …

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Characterization And Functional Analysis Of A Newly Identified Human Mt5-Mmp Transcript Variant Isolated From Multipotent Nt2 Cells, Heather Hamilton Ross Jan 2006

Characterization And Functional Analysis Of A Newly Identified Human Mt5-Mmp Transcript Variant Isolated From Multipotent Nt2 Cells, Heather Hamilton Ross

Theses and Dissertations

Membrane-type 5 matrix metalloproteinase (MT5-MMP) is unique among MMP family members as it is predominately expressed in the CNS. Its expression is ubiquitous during brain development and restricted to regions of neurogenesis and neuroplasticity in the adult. MT5-MMP is a mediator of pericellular proteolysis and is thought to have a functional impact on neurite outgrowth. The studies presented in this work were designed to examine MT5-MMP expression in cultured NT2 cells, a model of newogenesis and neuronal differentiation, and in adult neurogenic brain regions. We further sought to overexpress MT5-MMP and test the hypothesis that it plays a role in …

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An Evaluation Of Hospital Capital Investment After The Balanced Budget Act, Tae Hyun Kim Jan 2006

An Evaluation Of Hospital Capital Investment After The Balanced Budget Act, Tae Hyun Kim

Theses and Dissertations

Capital investments in the latest medical equipment and the replacement of aging facilities are important hospital decisions because they may have a significant influence on operating efficiencies and quality of care. However, hospitals experienced a minimal growth rate in capital expenditures which contributed to the aging of the hospital industry's asset base during the late 1990's and early 2000's. One of the underlying reasons behind this lack of growth might be the financial stresses that hospitals were facing after the Balanced Budget Act (BBA) of 1997, which significantly reducedMedicare reimbursement and had an adverse impact on the financial viability of …

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Developmental Expression Of Calcium-Binding Proteins In The Avcn And Mntb Of Normal Hearing And Congenitally Deaf Mice, John L. Roebel Jan 2006

Developmental Expression Of Calcium-Binding Proteins In The Avcn And Mntb Of Normal Hearing And Congenitally Deaf Mice, John L. Roebel

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This experiment analyzes synaptic differences in the central auditory pathway between normal hearing and congenitally deaf (dn/dn) mice, and provides valuable insight into central changes that correspond with human congenital deafness. Specifically, this experiment analyzes developmental expression of the Calcium (Ca2+)-binding proteins Calretinin (CR), Calbindin D-28k (CB) and Parvalbumin (PV) in large excitatory synapses in the anteroventral cochlear nucleus (AVCN) and the medial nucleus of the trapezoid body (MNTB) of normal and dn/dn mice. Immunofluorescence imaging with primary antibodies detecting CR, CB or PV was used to analyze the expression of each at 9 days, 13 days, 20 days, 30 …

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In Vitro Toxicity Assessment Of Silver Nanoparticles In Rat Alveolar Macrophages, Cataleya Carlson Jan 2006

In Vitro Toxicity Assessment Of Silver Nanoparticles In Rat Alveolar Macrophages, Cataleya Carlson

Browse all Theses and Dissertations

The present study was conducted to assess the toxicity of nanosized silver particles (Ag-15nm, 30nm and 55nm) in rat alveolar macrophages. For toxicity evaluations, cellular morphology, mitochondrial function (MTT assay), membrane leakage (LDH assay) and reactive oxygen species generation (ROS) were assessed after a 24h under control and exposed conditions. The morphological appearance of control and exposed cells were observed by an inverted, phase contrast microscope and the uptake of nanoparticles was observed using the CytoViva Ultra Resolution Imaging (URI) system. Morphological images captured at 100x magnification demonstrated that nanoparticle-exposed cells at higher doses became abnormal in size, and most …

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Clinical Presentation Of Acute Coronary Syndrome: Does Age Make A Difference? Implications For Emergency Nursing, Iesiah M. Harris Jan 2006

Clinical Presentation Of Acute Coronary Syndrome: Does Age Make A Difference? Implications For Emergency Nursing, Iesiah M. Harris

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Accurately recognizing symptoms of Acute Coronary Syndrome (ACS) presents a challenge to Emergency Department (ED) nurses and physicians. Due to the variety of clinical presentations in patients, ACS is frequently missed diagnosed. Studies demonstrate that many patients present with atypical symptoms and presentation varies based on gender. There is, however, a paucity of studies on the presentation of ACS in the elderly. With the older American population growing at exponential rates, it is imperative that studies are conducted to better comprehend ACS clinical presentation in the elderly. By 2020, it is anticipated, that 20% of the population will be 65 …

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Successful Social Movements And Political Outcomes: A Case Study Of The Women's Movement In Italy: 1943-48, Francesca Luciana Rubino Jan 2006

Successful Social Movements And Political Outcomes: A Case Study Of The Women's Movement In Italy: 1943-48, Francesca Luciana Rubino

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This thesis examines the definition of civil society, social movements and success and then analyzes these variables through a historical case study. It looks at the role of two women’s groups in Italy from 1943-48 as they worked to achieve three political goals (women’s suffrage, greater representation in politics, and the new constitution). The thesis will look at whether the variables necessary to social movement success were present in the movement in helping Italian women in the movement who mobilized and organized to achieve their said goals and objectives. It will conclude with remarks as to the lessons learned from …

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The Relationship Between Lactic Acid, Reactive Oxygen Species And The Hypoxia-Induced Acidification Seen In Chemosensitive Neurons Of The Nucleus Tractus Solitarius (Nts), Trevor Downing Jan 2006

The Relationship Between Lactic Acid, Reactive Oxygen Species And The Hypoxia-Induced Acidification Seen In Chemosensitive Neurons Of The Nucleus Tractus Solitarius (Nts), Trevor Downing

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The NTS is one of many sites of chemoreception meaning that it responds to changes in CO2 and pH. NTS neurons also acidify approximately 0.13 pH units in response to hypoxia. Experiments involved brainstem slices exposed to a control hypoxic bout followed by hypoxia in conjunction with different drugs. The drugs included fluorocitrate, 4-hydroxycinnamate, oxygen-glucose deprivation and iodoacetate. Iodoacetate produced the strongest blunting of the hypoxia-induced acidification and decreased the response by ~53%. Results from the studies using the superoxide probe DHE showed an increase in the levels of ROS during the hypoxic exposure prior to reoxygenation. Two ROS scavengers …

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Phenotypic Characterization Of Escherichia Coli Strains Taken From Human Intestinal And Urinary Tracts, Kruthi Murthy Jan 2006

Phenotypic Characterization Of Escherichia Coli Strains Taken From Human Intestinal And Urinary Tracts, Kruthi Murthy

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Escherichia coli (E. coli) is a gram negative bacterium commonly found as a commensal in the intestinal tract of humans and other warm blooded animals. The commensal strains of E. coli are non-pathogenic and do not cause an infection in the host. However, some strains of E. coli are pathogenic and can cause several diseases in humans that include neonatal meningitis, intestinal infections and urinary tract infections. Almost 80-85% of the uncomplicated urinary tract infections are caused by uropathogenic E. coli. Our project involved the characterization of 12 strains of E. coli, isolated from humans in health and disease. These …

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Models Of Disordered Media And Predictions Of Associated Hydraulic Conductivity, L. Aaron Blank Jr. Jan 2006

Models Of Disordered Media And Predictions Of Associated Hydraulic Conductivity, L. Aaron Blank Jr.

Browse all Theses and Dissertations

In the late 20th century there was a spill of Technetium in eastern Washington State at the US Department of Energy Hanford site. Resulting contamination of water supplies would raise serious health issues for local residents. Therefore, the ability to predict how these contaminants move through the soil is of great interest. The main contribution to contaminant transport arises from being carried along by flowing water. An important control on the movement of the water through the medium is the hydraulic conductivity, K, which defines the ease of water flow for a given pressure difference (analogous to the electrical conductivity). …

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Development Of An Audio Visual Tool For Medical Training At Kennedy Space Center, Rimawi, Nidal El Jan 2006

Development Of An Audio Visual Tool For Medical Training At Kennedy Space Center, Rimawi, Nidal El

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As part of an effort to improve efficiency of space-flight medical support at Kennedy Space Center, a training video was created to replace a series of lectures given before a launch or landing of the Space Shuttle. The video was designed to familiarize volunteer physicians from around the country with the specific emergency response protocols for a Space Shuttle launch or landing emergency at Kennedy Space Center. The methods used were consistent with standard film making techniques as outlined in several film making texts. The Production was divided into three phases; A pre-production phase wherein the research, screenwriting and production …

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Coronary Heart Disease Risk Stratification In Full-Time Miami Valley Hospital Employees, Vicki K. Streng Jan 2006

Coronary Heart Disease Risk Stratification In Full-Time Miami Valley Hospital Employees, Vicki K. Streng

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Heart disease is the number one killer in the United States (American Heart Association, 2005). The purpose of this study was to demonstrate the results of a twelve-week exercise program on coronary heart disease risk factors in full-time hospital employees. Methods: The participants were given cardiovascular, weight training, and flexibility recommendations to follow during a twelve-week period. The main heart disease risk factors measured before and after the completion of the exercise program were blood pressure, total cholesterol, HDL-cholesterol, and body mass index. The information was put into the Framingham Heart Score to estimate the participants’ 10-year risk of developing …

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Anti-System Parties:Policy Choices For Democracies A Study Of India's Bharatiya Janata Party And Austria's Freedom Party, Kristina M. Teater Jan 2006

Anti-System Parties:Policy Choices For Democracies A Study Of India's Bharatiya Janata Party And Austria's Freedom Party, Kristina M. Teater

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In the decades following WWII, countries across the globe witnessed the rise of anti-system parties. Political scientists have attributed their success to economic conditions, electoral systems, party systems and the electorate’s disaffection with mainstream parties. The analysis also suggests the influence of global factors. While the causes for success have been examined, effective policy choices for democracies have not been equally explored. This study makes the argument that by including anti-system parties in government, states are able to lessen the threat they pose to democracy. The analysis of India’s Bharatiya Janata Party and Austria’s Freedom party suggest that anti-system parties …

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Pyrrole Carboxamides As Potential Carbonic Anhydrase Inhibitors, Nishrin Ismailbhai Marketwala Jan 2006

Pyrrole Carboxamides As Potential Carbonic Anhydrase Inhibitors, Nishrin Ismailbhai Marketwala

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Carbonic anhydrases (CAs) are metalloenzymes that catalyze the reversible interconversion of CO2 and bicarbonate. We recently initiated a screen of a broad range of indoles and pyrroles possessing acyl-, carboxyl-, amido-, sulfonyl-, sulfamyl- and oxime- functionalities as potential inhibitors of á-CA II isozyme. As slight inhibition was observed in the case of 2-carboxamido-1-(phenylsulfonyl)pyrrole, and aware that pyrrole carboxamide derived sulfonamides had been previously demonstrated to possess CA inhibition, we sought to prepare a series of 1-(phenylsulfonyl)pyrrole-2-carboxamides but lacking a sulfonamide moiety to ascertain if the activity in our case might be due to a hitherto unrecognized pyrrole pharmacophore. To this …

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Kinetics And Passive Protection Efficacy Induced By Purified Ava Human Immunoglobulin G In Rabbits Against A Bacillus Anthracis Aerosol Challenge, Jennifer Lee Plahovinsak Jan 2006

Kinetics And Passive Protection Efficacy Induced By Purified Ava Human Immunoglobulin G In Rabbits Against A Bacillus Anthracis Aerosol Challenge, Jennifer Lee Plahovinsak

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The present study was conducted to determine the half-life, assess the toxicity, and passive protection efficacy of purified immunoglobulin G (IgG) from Anthrax Vaccine Adsorbed (AVA) vaccinated human donors. Half-life determinations were calculated from the reportable values obtained using the anti-PA ELISA assay and the Centers for Disease Control's (CDC) "ELISA for Windows" software. For toxicity evaluations animals were observed clinical for one hour post administration and for 14-days post-treatment. The protection efficacy was determined based upon the mortality results from a lethal Bacillus anthracis aerosol challenge. While no protection was achieved in this delayed exposure scenario, the study yielded …

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Active Regulation Of Speed During A Simulated Low-Altitude Flight Task: Altitude Matters!, April M. Bennett Jan 2006

Active Regulation Of Speed During A Simulated Low-Altitude Flight Task: Altitude Matters!, April M. Bennett

Browse all Theses and Dissertations

This study examined active regulation of speed during a low-altitude flight task as a function of global optical flow rate, speed, and the presence or absence of a concurrent altitude disturbance. The results showed that altitude clearly had an impact on speed control; specifically, control of speed was much more difficult when altitude disturbances were present. Even in the no altitude disturbance conditions, performance tended to be best at lower altitudes. Consistent with previous research, the results suggest that speed and altitude changes have additive effects on speed judgments. This is inconsistent with the simple global optical flow rate hypothesis …

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Topology Optimization Of Engine Exhaust-Washed Structures, Mark A. Haney Jan 2006

Topology Optimization Of Engine Exhaust-Washed Structures, Mark A. Haney

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Aircraft structure subjected to elevated temperature and acoustic loading present a challenging design environment. Thermal stress in a structural component has typically been alleviated by allowing thermal expansion. However, very little work has been done which directly addresses the situation where such a prescription is not possible. When a structural component has failed due to thermally-induced tensile stresses, the answer to the question of how best to stiffen the structure is far from trivial. In this work, we demonstrate that conventional stiffening techniques, for example, those which add material to the thickness of a failing panel, may actually increase the …

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Multi-Attribute Optimization Based On Conjoint Analysis, Hemanth K. Amarchinta Jan 2006

Multi-Attribute Optimization Based On Conjoint Analysis, Hemanth K. Amarchinta

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Over the last thirty years, there were tremendous advances in multidisciplinary design optimization in reducing computational cost, developing algorithms for efficient sensitivity analysis in reaching an optimum. Most of these efforts assumed a single objective (attribute) function and a multitude of constraints. Very little work has been done in including the designer's preferences as part of the optimization scheme and in addressing the ability to handle multiple attributes simultaneously. This need to develop a systematic method for including designer's preferences is the main focus of this research work. The concept of modeling preferences among multi-attribute alternatives is prevalent in consumer …

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Trademarks And The Landscape Of Imagination, Alan L. Durham Jan 2006

Trademarks And The Landscape Of Imagination, Alan L. Durham

Articles

No abstract provided.

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Thomas Aquinas And The Metaphysics Of Law, William S. Brewbaker Iii Jan 2006

Thomas Aquinas And The Metaphysics Of Law, William S. Brewbaker Iii

Articles

Despite modernity's longstanding aversion to metaphysics, legal scholars are increasingly questioning whether law can be understood in isolation from wider questions about the nature of reality. This Article examines perhaps the most famous of metaphysical legal texts—Thomas Aquinas's still widely read Treatise on Law—with a view toward tracing the influence of Thomas's metaphysical presuppositions. This Article shows that Thomas's account of human law cannot be fully understood apart from his metaphysics. Attention to Thomas's hierarchical view of reality exposes tensions between Thomas's “top-down” account of law and his sophisticated “bottom-up” observations. For example, Thomas grounds human law's authority in its …

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Tending To The Spirit: A Proposal For Healing The Hearts Of Black Children In Poverty Black Children And Their Families In The 21st Century: Surviving The American Nightmare Or Living The American Dream, Steven H. Hobbs, Shenavia Baity Jan 2006

Tending To The Spirit: A Proposal For Healing The Hearts Of Black Children In Poverty Black Children And Their Families In The 21st Century: Surviving The American Nightmare Or Living The American Dream, Steven H. Hobbs, Shenavia Baity

Articles

No abstract provided.

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History Belongs To The Winners: The Bazelon-Leventhal Debate And The Continuing Relevance Of The Process/Substance Dichotomy In Judicial Review Of Agency Action Administrative Law Discussion Forum, Ronald J. Krotoszynski Jr. Jan 2006

History Belongs To The Winners: The Bazelon-Leventhal Debate And The Continuing Relevance Of The Process/Substance Dichotomy In Judicial Review Of Agency Action Administrative Law Discussion Forum, Ronald J. Krotoszynski Jr.

Articles

No abstract provided.

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